David A Wolk
Professor of Neurology
Attending Neurologist, Hospital of the University of Pennsylvania
Faculty, Center for Cognitive Neuroscience, University of Pennsylvania
Fellow, Institute on Aging, University of Pennsylvania
Co-Director, Penn Memory Center
Director, Penn Alzheimer's Disease Research Center
Division Chief, Cognitive Neurology, University of Pennsylvania
Co-Director, Penn Institute on Aging
Department: Neurology
Contact information
Penn Memory Center
Ralston House
#212A
3615 Chestnut Street
Philadelphia, PA 19104
Ralston House
#212A
3615 Chestnut Street
Philadelphia, PA 19104
Office: 215 662-7810
Fax: 215 662-7812
Fax: 215 662-7812
Email:
david.wolk@uphs.upenn.edu
david.wolk@uphs.upenn.edu
Graduate Group Affiliations
Education:
BA (Psychology)
Dartmouth College, 1994.
MD (Medicine)
Johns Hopkins University School of Medicine, 1998.
BA (Psychology)
Dartmouth College, 1994.
MD (Medicine)
Johns Hopkins University School of Medicine, 1998.
Post-Graduate Training
Intern in Internal Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, 1998-1999.
Resident in Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA, 1999-2002.
Fellow in Cognitive Neurology, Brigham and Women's Hospital/Harvard Medical School, Boston, MA, 2002-2004.
Post-doctoral Research Fellow, Harvard University, Cambridge, MA, Brigham and Women's Hospital, Boston, MA, 2003-2006.
Intern in Internal Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, 1998-1999.
Resident in Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA, 1999-2002.
Fellow in Cognitive Neurology, Brigham and Women's Hospital/Harvard Medical School, Boston, MA, 2002-2004.
Post-doctoral Research Fellow, Harvard University, Cambridge, MA, Brigham and Women's Hospital, Boston, MA, 2003-2006.
Certifications
Diplomate of the American Board of Psychiatry And Neurology, Inc. , 2003.
Subspecialty Certification in Behavioral Neurology and Neuropsychiatry by the United Council of Neurologic Subspecialties, 2012.
Permanent linkDiplomate of the American Board of Psychiatry And Neurology, Inc. , 2003.
Subspecialty Certification in Behavioral Neurology and Neuropsychiatry by the United Council of Neurologic Subspecialties, 2012.
Description of Research Expertise
Episodic Memory, Event-related Potentials, transcranial direct current stimulation, MRI, Alzheimer's Disease, Dementia, Memory Disorders, Cognitive Neurology, Aging,Selected Publications
Wolk DA, Dickerson BC : Fractionating verbal episodic memory in Alzheimer's disease. NeuroImage 54(2): 1530-9, Sep 2010.Wolk DA, Dickerson BC: Apolipoprotein E (APOE) genotype has dissociable effects on memory and attentional-executive network function in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America 107(22): 10256-61, Jun 2010 Notes: Featured article in Alzheimer Research Forum: ApoE and Brain Networks—The Anatomy of a Risk Factor, May 28, 2010.
Wolk DA, Dunfee KL, Dickerson BC, Aizenstein HJ, Dekosky ST: A medial temporal lobe division of labor: Insights from memory in aging and early Alzheimer disease. Hippocampus 21(5): 461-6, Mar 2010.
Wolk DA, Price JC, Saxton JA, Snitz BE, James JA, Lopez OL, Aizenstein HJ, Cohen AD, Weissfeld LA, Mathis CA, Klunk WE, DeKosky ST: Amyloid imaging in mild cognitive impairment subtypes. Annals of Neurology 65(5): 557-68, May 2009.
Dickerson BC, Wolk DA: MRI cortical thickness biomarker predicts AD-like CSF and cognitive decline in normal adults. Neurology 78(2): 84-90, Dec 2011 Notes: Featured editorial on manuscript: Resnick SM; Scheltens P. MRI-based biomarkers of preclinical AD: An Alzheimer signature. Neurology: 78(2): 80-81. Featured article in Alzheimer Research Forum. Is Structural MRI Closing In on Preclinical AD Biomarker? December 27, 2011.
Pluta J, Yushkevich P, Das S, Wolk D: In vivo Analysis of Hippocampal Subfield Atrophy in Mild Cognitive Impairment via Semi-Automatic Segmentation of T2-Weighted MRI. Journal of Alzheimer's Disease 31(1): 85-99, Jan 2012.
Wolk DA, Price JC, Madeira C, Saxton JA, Snitz BE, Lopez OL, Mathis CA, Klunk WE, Dekosky ST: Amyloid imaging in dementias with atypical presentation. Alzheimer's & Dementia 8(5): 389-98, Jan 2012.
Wolk DA, Mancuso L, Kliot D, Arnold SE, Dickerson BC: Familiarity-based memory as an early cognitive marker of preclinical and prodromal AD. Neuropsychologia 51(6): 1094-102, Mar 2013.