faculty photo

Raymond Edward Soccio, MD, PhD

Adjunct Assistant Professor of Medicine
Department: Medicine

Contact information
5906 Ryland Drive
Bethesda, MD 20817
Education:
BA (Biochemical Sciences, summa cum laude)
Harvard University, Cambridge, MA, 1997.
PhD (Biomedical Sciences)
Rockefeller University, New York, NY, 2004.
MD
Weill Medical College of Cornell University, New York, NY, 2005.
Post-Graduate Training
Intern and Resident in Internal Medicine, Physician-Scientist Pathway, Hospital of the University of Pennsylvania, Philadelphia, PA, 2005-2007.
Fellow in Endocrinology, Diabetes, and Metabolism, Hospital of the University of Pennsylvania, Philadelphia, PA, 2007-2011.
Senior Research Fellow in Medicine, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA, 2011-2012.
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Description of Clinical Expertise

Obesity, Metabolic Syndrome

Description of Research Expertise

Nuclear Receptors, Genetics of Gene Regulation, Lipid Metabolism

Selected Publications

Bi X, Kuwano T, Lee PC, Millar JS, Li L, Shen Y, Soccio RE, Hand NJ, Rader DJ: ILRUN, a Human Plasma Lipid GWAS Locus, Regulates Lipoprotein Metabolism in Mice. Circ Res 127(11): 1347-1361, Nov 2021 Notes: doi: 10.1161/CIRCRESAHA.120.317175.

Soccio Raymond E: Galectin-3 in NAFLD: Therapeutic Target or Noncausal Biomarker? J Clin Endocrinol Metab 106(9): e3773-e3774, August 2021 Notes: doi: 10.1210/clinem/dgab363.

Jiao X, Tian L, Zhang Z, Balcerek J, Kossenkov AV, Casimiro MC, Wang C, Liu Y, Ertel A, Soccio RE, Chen ER, Liu Q, Ashton AW, Tong W, Pestell RG: : Pparγ1 Facilitates ErbB2-Mammary Adenocarcinoma in Mice. Cancers (Basel) 13(9): 2171, April 2021 Notes: doi: 10.3390/cancers13092171.

Shen Y, Su Y, Silva FJ, Weller AH, Sostre-Colón J, Titchenell PM, Steger DJ, Seale P, Soccio RE: Shared PPARα/γ Target Genes Regulate Brown Adipocyte Thermogenic Function. Cell Reports 30(9): 3079-3091, March 2020 Notes: doi: 10.1016/j.celrep.2020.02.032.

Soccio, RE: Chapter 28: Hepatic Nuclear Receptors. The Liver: Biology and Pathobiology, Sixth Edition. John Wiley & Sons Ltd. 2020.

Benson, Kiara K; Hu, Wenxiang; Weller, Angela H; Bennett, Alexis H; Chen, Eric R; Khetarpal, Sumeet A; Yoshino, Satoshi; Bone, William P; Wang, Lin; Rabinowitz, Joshua D; Voight, Benjamin F; Soccio, Raymond E.: Natural human genetic variation determines basal and inducible expression of PM20D1, an obesity-associated gene. Proc Natl Acad Sci U S A 116(46): 23232-23242, Nov 2019 Notes: doi: 10.1073/pnas.1913199116. Epub 2019 Oct 28.

Yachen Shen, Yvonne Su, Angela Weller, Raymond Soccio: PPARα and PPARγ gene regulation in brown fat thermogenesis. Cold Spring Harbor Mechanisms of Metabolic Signalling Meeting, NY May 2019.

Kiara K. Benson, Wenxiang Hu, Angela H. Weller, Alexis H. Bennett, Eric R. Chen, Sumeet A. Kheterpal, Satoshi Yoshino, Wang L, Joshua D. Rabinowitz, Benjamin F. Voight, Mitchell A. Lazar, Raymond E. Soccio: Natural Genetic Variation in Humans Determines Basal and Inducible Expression of PM20D1, a Putative Thermogenic Gene. Endocrine Society Annual Meeting, New Orleans, LA March 2019.

Hu Wenxiang, Jiang Chunjie, Guan Dongyin, Dierickx Pieterjan, Zhang Rong, Moscati Arden, Nadkarni Girish N, Steger David J, Loos Ruth J F, Hu Cheng, Jia Weiping, Soccio Raymond E, Lazar Mitchell A: Patient Adipose Stem Cell-Derived Adipocytes Reveal Genetic Variation that Predicts Antidiabetic Drug Response. Cell stem cell 24(2): 299-308.e6, Feb 2019.

Zhang Xuan, Xue Chenyi, Lin Jennie, Ferguson Jane F, Weiner Amber, Liu Wen, Han Yumiao, Hinkle Christine, Li Wenjun, Jiang Hongfeng, Gosai Sager, Hachet Melanie, Garcia Benjamin A, Gregory Brian D, Soccio Raymond E, Hogenesch John B, Seale Patrick, Li Mingyao, Reilly Muredach P: Interrogation of nonconserved human adipose lincRNAs identifies a regulatory role of in adipocyte metabolism. Science translational medicine 10(446), Jun 2018.

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Last updated: 04/05/2022
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