Lab Members


Faculty

D. Kacy Cullen

D. Kacy Cullen

Principal Investigator
 dkacy@pennmedicine.upenn.edu

Ph.D., Biomedical Engineering, Georgia Institute of Technology (2005)

M.S., Mechanical Engineering, Georgia Institute of Technology (2002)

B.S., Mechanical Engineering, Georgia Institute of Technology (2000)


Postdoctoral Fellows

Kathryn L. Wofford, Ph.D.

Kathryn L. Wofford, Ph.D.

 kwofford@pennmedicine.upenn.edu

Projects
Understanding and Employing the Innate Immune System to Promote Regeneration Following Traumatic Brain Injury

Awards & Fellowships
Brain Injury Training Grant “Understanding and Exploiting Innate Immune Cell Infiltration into the Brain Following Trauma” NIH NRSA T32.

Degrees
Ph.D., Biomedical Engineering, Drexel University (2019)
M.S., Biomedical Engineering, Drexel University (2015)
B.A., Biophysics and Psychology with Honors, Austin College (2012)

Robert B. Shultz, Ph.D.

Robert B. Shultz, Ph.D.

 bob.b.shultz@gmail.com

Projects
Tissue-Engineered Axon Fusion for Immediate Recovery Following Nerve Injury

Awards & Fellowships
NIH NRSA T32 Fellowship (2019-2021); T32 Title: “Training Without Borders: Translating Research in Regenerative Medicine”, lead organization: Rutgers University (PI: Joachim Kohn)

Degrees
Ph.D., Biomedical Engineering, Drexel University (2019)
B.S., Biomedical Engineering, Rutgers University (2012)

Suradip Das, Ph.D.

Suradip Das, Ph.D.

 suradip@pennmedicine.upenn.edu

Projects
Tissue-Engineered Neural Constructs for Neuromuscular Injury Repair

Degrees
Ph.D., Biosciences & Bioengineering, Indian Institute of Technology Guawahati (2016)

John C. O'Donnell, Ph.D.

John C. O'Donnell, Ph.D.

 john.charles.odonnell@gmail.com

Projects
Modeling Disorders of Consciousness
Tissue-Engineered Living Scaffolds for Neuroregeneration
Hippocampal Circuitry Disruption Following Mild Traumatic Brain Injury

Awards & Fellowships
NIH NRSA F32 Fellowship, Modeling Disorders of Consciousness(2016-2019)

Degrees
Ph.D., Neuropharmacology, University of Pennsylvania (2016)
M.S., Biology, Towson University (2009)
B.A., Biology, LaSalle University (2004)


Research Specialists

Kevin D. Browne, B.A.

Kevin D. Browne, B.A.

 kbrowne@pennmedicine.upenn.edu

Projects
Development of a Large Animal Model of Neurointensive Care and Recovery
Plasmalemmal Permeability and Cell Death after Non-Impact Head Trauma and Blast Injury
In Vivo Efficacy Testing of Tissue-Engineered Nerve Grafts for Peripheral Nerve Injury
Micro-Tissue Engineered Neural Networks to Restore Brain Circuitry


Graduate Students

Dayo O. Adewole, M.S.E.

Dayo O. Adewole, M.S.E.

Doctoral Candidate - Bioengineering
 oadewole@seas.upenn.edu

Projects
The Application of Micro-Tissue Engineered Neural Networks as Living Electrodes for Sensorimotor Information

Awards & Fellowships
NIH NRSA T32 Fellowship (2018 - 2020)
NSF Graduate Research Fellowship, Micro-Tissue Engineered Neural Networks as "Living Electrodes" to Relay Sensory Information for a Brain-Machine Interface(2015-2018)

Degrees
M.S.E., Robotics, University of Pennsylvania (2015)
B.S.E., Bioengineering, University of Pennsylvania (2015)

Carolyn E. Keating, B.A.

Carolyn E. Keating, B.A.

Doctoral Candiate - Neuroscience
 ckeating@pennmedicine.upenn.edu

Projects
Acute Permeability & Synucleinopathy in TBI and 3D Neural Cell Culture

Degrees
B.A., Neuroscience, Colgate University (2012)

 

Wisberty J. Gordián-Vélez, B.S.

Wisberty J. Gordián-Vélez, B.S.

Doctoral Candidate - Bioengineering
 wgord@seas.upenn.edu

Projects
Transplantable Axonal Tracts as "Living DBS" for Dopamine Replacement in Parkinson's Disease
Three-Dimensional Human Axon Tracts Derived from Cerebral Organoids

Awards & Fellowships
NSF Graduate Research Fellowship, Light-Mediated Neuromodulation of the Inflammatory Reflex Using Tissue Engineered Interfaces with Living Post-Ganglionic Sympathetic Axon Tracts(2018-2021)

Degrees
B.S., Chemical Engineering, University of Puerto Rico, Mayagüez Campus (2016)

Erin M. Purvis, B.S.

Erin M. Purvis, B.S.

Doctoral Student - Neuroscience
 epurvis@pennmedicine.upenn.edu

Projects
Tissue-Engineered Rostral Migratory Stream for Directed Neuronal Replacement 

Awards & Fellowships
Predoctoral Fellowship, National Science Foundation (GRFP)

Degrees
B.S., Biopsychology, University of California at Santa Barbara (2017)

Justin C. Burrell, M.S.

Justin C. Burrell, M.S.

Doctoral Candidate - Bioengineering
 burrellj@pennmedicine.upenn.edu

Projects
Development of Micro-Tissue Engineered Nerve Grafts to Preserve Peripheral Nerve Regeneration Capacity and Maintain the Distal Nerve Pathway
In Vivo Efficacy Testing of Tissue Engineered Nerve Grafts for Peripheral Nerve Injury
Micro-Tissue Engineered Neural Networks to Restore Brain Circuitry

Degrees
M.S., Neuroscience, Tulane University (2013)
B.S., Psychology, Tulane University (2012)

Victor Acero

Victor Acero

Doctoral Student - Bioengineering
 vacero@seas.upenn.edu

Projects
Engineering an In Vitro Model of Hippocampal Networks

Awards & Fellowships
NSF Graduate Research Fellowship, High-Efficiency Kirigami Vase Water Harvester(2018-2021)
Fontaine Fellowship (2017)

Degrees
B.S., Engineering Science, Pennsylvania State University (2017)

Mike R. Grovola

Mike R. Grovola

Doctoral Candidate - Biomedical Engineering
 mgrovola@pennmedicine.upenn.edu

Projects
Neuroinflammation and Axonal Pathology Associated with Traumatic Brain Injury in Swine

Degrees
M.S., Drexel University
B.A., University of Richmond


Undergraduate Students

Kaila Helm

Kaila Helm

BAS Candidate - Biological Basis of Behavior (2020)
 khelm@sas.upenn.edu

Projects
Tissue-Engineered Living Scaffolds for Neuroregeneration

Nicholas Paleologos

Nicholas Paleologos

BAS Candidate - Biological Basis of Behavior (2020)
 npale@sas.upenn.edu

Projects
Neuroinflammation and Axonal Pathology Associated with Traumatic Brain Injury in Swine

Melanie Hilman

Melanie Hilman

BSE Candidate - Bioengineering (2020)
 mhilman@seas.upenn.edu

Projects
Stretch Grown Tissue-Engineered Muscle for Volumetric Muscle Loss Repair

Saarang Karandikar

Saarang Karandikar

BAS Candidate - Biological Basis of Behavior (2020)
 saarangk@sas.upenn.edu

Projects
Upscaling of Micro-Tissue Engineered Neural Networks for Sensorimotor "Living Electrode" Applications

Lab Alumni

Vishal Tian: Undergraduate Student, Bioengineering, University of Pennsylvania
Project: Optogenetic Stimulation of Motor Neurons in a Tissue Engineered Nerve Graft to Enhance Axonal Outgrowth

Kritika S. Katiyar, Ph.D.: Bioengineering, Drexel University
Projects: Tissue-Engineered Living Scaffolds for Neuroregeneration; Molecular Mechanisms of Axon-Mediated Axon Regeneration; 3-D Neural Cell Culture Techniques

Fellowship: NIH NRSA F31 Fellowship, Mechanisms for Axonal Guidance Using Living Tissue Engineered Scaffolds (2015-2018)

Halimulati Kaisaier: Undergraduate Student, Bioengineering, University of Pennsylvania
Project: Development of Innervated Tissue Engineered Muscle on Aligned Nanofibers for Volumetric Muscle Loss Repair

Laura A. Struzyna, Ph.D.: Bioengineering, University of Pennsylvania
Projects: Tissue-Engineered Biohybrid Neuroprosthetic Interfaces; Micro-Tissue Engineered Neural Networks to Restore Brain Circuitry; Neurophysiological Assessment of Nervous System Repair

Fellowship: NSF Graduate Research Fellowship, Tissue Engineered Constructs for Neural Repair (2013-2016)

Kate Panzer: Undergraduate Student, Bioengineering, University of Pennsylvania
Project: Tissue-Engineered Living Scaffolds for Neuroregeneration

Joseph Maggiore: Undergraduate Student, Bioengineering, University of Pennsylvania
Project: In Vivo Efficacy Testing of Tissue-Engineered Nerve Grafts for Peripheral Nerve Injury

Dan Brown, B.S.: Research Specialist
Projects: In Vivo Efficacy Testing of Tissue-Engineered Nerve Grafts for Peripheral Nerve Injury; Chronic Neurodegenerative and Neurophysiological Sequela in TBI

Chelsea Wallace, D.V.M.: Staff Veterinarian
Project: Effects of FK506 on Host Regeneration Through Tissue-Engineered Allograft and Xenograft Nerve Constructs

Sanford Roberts, B.A.: Medical Student
Project: Evaluation of Polyethylene Glycol as an Agent of Rapid Axonal Fusion Following Nerve Transection

Dmitriy Petrov, M.D.: Neurosurgical Resident
Project: Micro-Tissue Engineered Neural Networks to Restore Brain Circuitry

Fellowship: Codman Neurotrauma & Critical CareResearch Fellowship, Micro-Tissue Engineered Neural Networks to Restore Hippocampal Circuitry (2015-2016)

Carla Winter: Undergraduate Student, Bioengineering, University of Pennsylvania
Project: Tissue-Engineered Living Scaffolds for Neuroregeneration

Tina Lulla: Undergraduate Student
Project: Micro-Tissue Engineered Neural Networks to Restore Brain Circuitry

Jimmy Harris: Postdoctoral Fellow
Project: Chronic Neurodegenerative and Neurophysiological Sequela in TBI & Micro-Tissue Engineered Neural Networks to Restore Brain Circuitry

Carla Hernandez: Undergraduate Student
Project: Histological Techniques to Assess Neurotrauma Pathology and Repair Strategies

Ryan Zahalka: Undergraduate Student
Project: Molecular Mechanisms of Axon-Mediated Axon Regeneration; Environmental Control for Bench-Top Mechanobioreactor

Ellie Boyle: Undergraduate Student
Project: Tissue Engineering Strategies for Nerve Regeneration

Anthony Parisi: Undergraduate Student
Project: Quantitative Neuropathological Analyses of Rodent and Porcine Tissue Following Traumatic Brain Injury

Joseph Morand, B.S.: Research Specialist
Project: In Vivo Efficacy Testing of Tissue Engineered Nerve Grafts for Peripheral Nerve Injury

Emory Kuo, M.S.: Predoctoral Fellow
Project: Tissue Engineering for Neuroregeneration, Chronic Neurodegenerative and Neurophysiological Sequela in TBI

Constance Mietus, B.A: Research Specialist
Project: Neural Cell Biophysical Responses in Blast-Induced Traumatic Brain Injury

Joe Frasca, Ph.D.: Postdoctoral Fellow
Project: Chronic Neurodegenerative and Neurophysiological Sequela of Closed-Head TBI

John A. Wolf, Ph.D.: Postdoctoral Fellow, University of Pennsylvania
Project: Functional Reorganization of Limbic Circuitry After TBI in Swine, Biohybridized Neural Tissue-Engineered Constructs for Electrical Interface with Peripheral Nerve

Matthew Weingard: Medical Student, Tulane
Project: Tissue Engineering with Primary Cortical Neurons

Scott Yerganian: Bioengineering, University of Pennsylvania
Project: Mechanisms of Axon-Mediated Axon Regeneration

Janid Kiely: Biophysics, University of Pennsylvania
Project: Biomechanics of Concussion: Pathobiological Implications of Acute Cellular Damage

Arshneel Kochar: Medical Student, CWRU  
Project: Tissue Engineering Micro-Conduits for Targeted Axonal Tract Reconstruction 

Billy Lane: Pre-Med, Notre Dame
Project: Mechanisms of Axonal Degeneration in a Swine Model of Closed-Head TBI

Jonathan Yu: Biology, Haverford College
Project: Tissue Engineering Micro-Conduits for Targeted Axonal Tract Reconstruction