People
Prinicipal Investigator (PI)
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Read More about D. Kacy Cullen
D. Kacy Cullen
Professor of Neurosurgery & Bioengineering
dkacy@pennmedicine.upenn.edu
Ph.D., Biomedical Engineering, Georgia Institute of Technology (2005)
M.S., Mechanical Engineering, Georgia Institute of Technology (2002)
B.S., Mechanical Engineering, Georgia Institute of Technology (2000)
Faculty
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Read More about John C. O'Donnell, Ph.D.
John C. O'Donnell, Ph.D.
Research Assistant Professor of Neurosurgery
Email John C. O'Donnell, Ph.D.
John C. O'Donnell, Ph.D.
Research Assistant Professor of Neurosurgery
john.charles.odonnell@gmail.com
Projects
Improving Recovery from Moderate-to-Severe Traumatic Brain Injury
Coma and Disorders of Consciousness
Neurocritical Care (e.g., intracranial hypertension)
Tissue Engineered Glial Constructs
Human Tissue Engineered TestbedsAwards & Fellowships
VA RR&D CDA2, Translational Modeling of Brain Injury Rehabilitation to Maximize Recovery (2021-2026)
NIH NRSA F32 Fellowship, Modeling Disorders of Consciousness (2017-2020)Degrees
Ph.D., Neuropharmacology, University of Pennsylvania (2016)
M.S., Biology, Towson University (2009)
B.A., Biology, LaSalle University (2004) -
Read More about Suradip Das, Ph.D.
Suradip Das, Ph.D.
Research Assistant Professor of Neurosurgery
suradip@pennmedicine.upenn.edu
Projects
Tissue-Engineered Neural Constructs for Neuromuscular Injury RepairDegrees
Ph.D., Biosciences & Bioengineering, Indian Institute of Technology Guawahati (2016)
Lab Management
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Read More about Kevin D. Browne, B.A.
Kevin D. Browne, B.A.
Research Project Manager/Lab Manager
kbrowne@pennmedicine.upenn.edu
Projects
Development of a Large Animal Model of Neurointensive Care and Recovery
Plasmalemmal Permeability and Cell Death after Non-Impact Head Trauma and Blast Injury
In Vivo Efficacy Testing of Tissue-Engineered Nerve Grafts for Peripheral Nerve Injury
Micro-Tissue Engineered Neural Networks to Restore Brain Circuitry -
Read More about Elizabeth Krizman (Liz)
Elizabeth Krizman (Liz)
Center Research Coordinator (Lab Mom)
elizabeth.Krizman@pennmedicine.upenn.edu
Glia Team Lead
Professional Mission Statement
I am committed to helping the next generation of scientists by offering guidance and leveraging my expertise to help advance their careers and research.
Research Associates
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Read More about Dimple Chouhan, Ph.D.
Dimple Chouhan, Ph.D.
dimple.chouhan@pennmedicine.upenn.edu
Projects
Biofabricatioon of nigrostriatal pathway for the treatment of Parkinson's disease
Tissue-engineered nigrostriatal pathway as test-bed for evaluating axonal pathophysiology in Parkinson's diseaseDegrees
Ph.D., Biosciences & Bioengineering, Indian Institute of Technology Guwahati, India (2019)
B.Tech., Electronics and Communication, Rajasthan Technical University, India (2012) -
Read More about Mykhailo Tatarchuk
Mykhailo Tatarchuk
Research Project Manager
mykhailo.Tatarchuk@pennmedicine.upenn.edu
Projects
Focusing on pioneering the development of next-generation technologies that enable rapid recovery after nerve injury. Nerve Coupler device. Nerve Tape. Tissue Engineered Neural Networks for Spinal Cord Injury Repair.
Degrees
MD. National Medical University, Kyiv, Ukraine (2005)
Ph.D., National Academy of Medical Sciences, Kyiv, Ukraine (2015)
Neurosurgeon, 15 years peripheral nerves surgery work experience
Postdoctoral Fellows
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Read More about Jay Dave, Ph.D.
Jay Dave, Ph.D.
Postdoctoral Researcher (co-advised by Dr. Suradip Das)
jay.dave2@pennmedicine.upenn.edu
Projects:
3D printing human-scale muscle tissue with preformed axonal and vascular network.Degrees:
Ph.D. Biotechnology, Savitribai Phule Pune University (2024)
M.Sc. Biotechnology, Savitribai Phule Pune University (2017)
B.Sc. Biotechnology, Savitribai Phule Pune University (2015)
Doctoral Students
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Read More about Dimitris Boufidis
Dimitris Boufidis
Doctoral Student - Bioengineering (Co-advised by Dr. Flavia Vitale)
Email Dimitris Boufidis
Dimitris Boufidis
Doctoral Student - Bioengineering (Co-advised by Dr. Flavia Vitale)
boufidis@engineering.upenn.edu
Co-advised by Dr. Flavia Vitale
Awards & Fellowships:
Alexander S. Onassis Foundation (2023), A.G. Leventis Foundation (2024)Education:
B.Eng., Bioengineering, University of Sheffield, UK
MS, Bioengineering, University of Pennsylvania, USA -
Read More about Saarang Karandikar
Saarang Karandikar
Doctoral Student - Bioengineering
saarangk@sas.upenn.edu
Projects
Upscaling of Micro-Tissue Engineered Neural Networks for Sensorimotor "Living Electrode" ApplicationsDegrees
B.A.S., Neuroscience, University of Pennsylvania (2020) -
Read More about Viviana (vivi) Alpizar Vargas
Viviana (vivi) Alpizar Vargas
Doctoral Student - Bioengineering
valpizar@seas.upenn.edu
Project: Engineering Multi-Modal Axon-Based Living Electrodes to Investigate Human Neural Circuit Function
Awards & Fellowships: Fontaine Fellowship
Education:
B.S., Bioengineering, University of Maryland
B.S., Neuroscience, University of Maryland -
Read More about Yihan Xie
Yihan Xie
Doctoral Student - Bioengineering
Yihan.Xie1@pennmedicine.upenn.edu
Degrees
B.S. Brain and Cognitive Science; B.A. Mathematics University of Rochester (2022) -
Read More about Pantea Vafaei
Pantea Vafaei
Doctoral Student - Bioengineering
vafaei@engineering.upenn.edu
Education: B.S., Bioengineering, University of Maryland
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Read More about Chunghsun Lin
Chunghsun Lin
Doctoral Student - Bioengineering (Co-advised by Dr. Suradip Das)
cxlin@engineering.upenn.edu
Co-advised by Dr. Kacy Cullen and Dr. Suradip Das
Project: Engineering a 3D Skeletal Muscle Triculture Platform Toward Disease Modeling
Degree: M.S.E, Bioengineering, University of Pennsylvania
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Read More about Will Dunne
Will Dunne
Doctoral Student - Bioengineering (Co-advised by Dr. Flavia Vitale)
wdunne@engineering.upenn.edu
Degrees: B.S., Biomedical Engineering, Georgia Institute of Technology
Undergraduate Students
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Read More about Mustafo Mustafokulov
Mustafo Mustafokulov
Undergraduate Student - Finance and Biology (2027)
mustafo@sas.upenn.edu
Project: Tissue Engineered Muscular Units and Electrospun Nanofiber Materials
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Read More about Chantal van Dongeren
Chantal van Dongeren
Undergraduate Student - Bioengineering (2028)
cvandong@seas.upenn.edu
Project:
Towards a Functional In Vitro Model of Hippocampal Circuitry (under Dr. Cybelle Smith)
Technicians
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Read More about David Clizbe
David Clizbe
Research Specialist
David.Clizbe@pennmedicine.upenn.edu
Projects:
Peripheral Nerve Regeneration Team and Spinal Cord Regeneration TeamDegrees:
BS and MS from the University of Delaware -
Dan Han
Dan Han
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Adam Weissman
Adam Weissman
Lab Affiliates
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Read More about JoonHyung Park, Ph.D.
JoonHyung Park, Ph.D.
Postdoctoral Researcher (Lee Lab)
joonhyung.park@pennmedicine.upenn.edu
Projects
Tissue Engineered Nerve Grafts (TENG) with temporal and spatial regulation of neurogenic factors
Vascularized, Innervated Tissue Engineered Muscle (V-InTEM) implants for regeneration following nerve compressionAwards & Fellowship
VA T-TERM Fellowship (2026-2027)Education
Ph.D., Pathobiology, Columbia University (2025)
M.A., Pathobiology, Columbia University (2021)
M.Phil., Pathobiology, Columbia University (2021)B.A., Neuroscience, University of Pennsylvania (2016)
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Read More about Robert B. Shultz, Ph.D.
Robert B. Shultz, Ph.D.
bob.b.shultz@gmail.com
Projects
Tissue-Engineered Axon Fusion for Immediate Recovery Following Nerve InjuryAwards & Fellowships
NIH NRSA T32 Fellowship (2019-2021); T32 Title: “Training Without Borders: Translating Research in Regenerative Medicine”, lead organization: Rutgers University (PI: Joachim Kohn)Degrees
Ph.D., Biomedical Engineering, Drexel University (2019)
B.S., Biomedical Engineering, Rutgers University (2012) -
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Lab Alumni
Prior Predoctoral Trainees:
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Kiera Yankson |
Bioengineering, UPenn |
Optically Controlled Living Electrodes for Biologically-Based Neuromodulation |
2020 – 2026 |
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Kyndall Nicholas |
Neuroscience, UPenn |
Bioactive Lipid Engineering for Neuroprotection in TBI |
2021 – 2026 |
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Melanie Hilman |
Bioengineering, UPenn |
Role of Innervation in Engineered Muscle |
2021 – 2025 |
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Erin Purvis*
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Neuroscience, UPenn |
Directing Immature Neuronal Migration to Investigate Cell Fate Determination *NSF Graduate Research Fellow 2019-2023 |
2019 – 2024 |
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Victor Acero* |
Bioengineering, UPenn |
Tissue Engineered Hippocampal Networks *NSF Graduate Research Fellow 2018-2021 |
2018 – 2024 |
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Wisberty J. Gordián Vélez* |
Bioengineering, UPenn |
Implantable Axon Tracts as “Living Electrodes” for Biologically Based Neuromodulation *NSF Graduate Research Fellow 2018-2021 |
2016 – 2022 |
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Michael R. Grovola, PhD |
Biomedical Sciences, Drexel |
Characterization of Neuropathology and Neuroinflammatory Cascades after Mild TBI in Swine |
2016 – 2021 |
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Oladayo O. Adewole*, PhD |
Bioengineering, UPenn |
Microtissue Engineered Neural Networks as Optically-Controlled Living Electrodes for Circuit Modeling and Neuroprosthetics *NSF Graduate Research Fellow 2015-2018 |
2015 – 2021 |
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Justin C. Burrell*, PhD |
Bioengineering, UPenn |
Implantable Micro-Tissue Engineered Nerve Grafts to Maintain Regenerative Capacity and Facilitate Functional Recovery Following Nervous System Injury *T-TERM Fellow |
2017 – 2020 |
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Carolyn E. Keating, PhD |
Neuroscience, UPenn |
Characterizing and Manipulating Neuronal Plasma Membrane Mechanoporation in TBI |
2015 – 2020 |
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Kathryn L. Wofford, PhD |
Biomedical Engineering, Drexel |
Utilizing the Innate Immune System to Mitigate Secondary Injury Following TBI |
2015 – 2019 |
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Laura A. Struzyna*#, PhD |
Bioengineering, UPenn |
Tissue Engineered Nigrostriatal Pathway for Treatment of Parkinson’s Disease *NSF Graduate Research Fellow 2013-2016 #NIH NRSA T32 Fellow 2016-2018 |
2013 – 2019 |
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Kritika S. Katiyar*, PhD |
Biomedical Engineering, Drexel |
Molecular Mediators of Modality-Dependent Axon Facilitated Axon Regeneration Using Novel Tissue Engineered Nerve Grafts *NIH NRSA F31 Fellow 2015-2018 |
2012 – 2018 |
Prior Postdoctoral Trainees:
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Dayo Adewole, PhD |
Bioengineering, UPenn |
Tissue Engineered Living Electrodes for Synaptic-Based Precision Neuromodulation |
2024 – 2026 |
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Cybelle Smith, PhD |
Psychology, Univ. of Illinois at Urbana-Champaign |
Modular Engineered Neural Testbeds Approximating Large-Scale Functional Networks |
2023 – 2026 |
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Mykhailo Tatarchuk, MD, PhD |
Romodanov Neurosurgery Inst., Nat. Acad. of Med. Sci, Dept. of Reconstructive Neurosurgery, Kyiv, Ukraine |
Advanced Neurosurgical Strategies for Peripheral Nerve Repair |
2023 – 2025 |
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Justin Burrell, PhD |
Bioengineering, UPenn |
Regenerative Therapies for Peripheral Nerve Repair |
2021 – 2025 |
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Dimple Chouhan, PhD |
Biosciences & Bioengineering, Indian Institute of Technology |
Advanced Biomanufacturing of Tissue Engineered Nigrostriatal Pathways to Treat Parkinson’s Disease |
2020 – 2025 |
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Michael Grovola, PhD |
Neuroscience, Drexel |
Neuroinflammation in TBI |
2021 – 2025 |
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Erin Purvis, PhD |
Neuroscience, UPenn |
Directing Immature Neuronal Migration to Investigate Cell Fate Determination |
2024 |
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Yohannes Ghenbot, MD |
Neurosurgery, UPenn |
Human Stem Cell Derived Tissue Engineering Spinal Tracts for Treatment of Spinal Cord Injury |
2023 – 2024 |
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Kathryn Wofford*#, PhD |
Biomedical Engineering, Drexel |
Reprogramming Macrophages for Neuroprotection and Plasticity Post-TBI *Fellowship: NIH NRSA “Brain Injury Training Grant” 2019-2020; #NIH NRSA F32 2020-2022; !NIH K99/R00 2022-2027 |
2019 – 2024 |
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Connor Wathen, MD |
Neurosurgery, UPenn |
Tissue Engineering Spinal Tracts for Reconstruction After Spinal Cord Injury |
2022 – 2023 |
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Caroline Blevins, DVM |
Pathobiology, UPenn |
Lipid Engineering to Prevent TBI Associated Neuronal Injury |
2020 – 2021 |
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Robert Schultz*, PhD |
Biomedical Engineering, Drexel |
Tissue Engineered Axon Fusion for Immediate Recovery Following Nerve Injury *Training Without Borders NRSA T32 Fellow 2019-2021 |
2019 – 2021 |
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Elisia Clark*, PhD |
Pharmacology, UPenn |
Tissue Engineered Nigrostriatal Pathway to Study the Pathophysiology of Parkinson's Disease*Clinical and Translational Science Award Fellow 2018-2020 |
2018 – 2020 |
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John O’Donnell*, PhD |
Pharmacology, UPenn |
Modeling Disorders of Consciousness in Swine *NIH NRSA F32 Fellow 2016-2019 |
2016 – 2021 |
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Suradip Das, PhD |
Biosciences & Bioengineering, Indian Institute of Technology |
Motor-Specific Tissue Engineered Nerve Grafts for Major Peripheral Nerve Repair |
2016 – 2021 |
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Chelsea Wallace, DVM |
Pathobiology, UPenn |
Immunosuppressive Therapy to Enhance Efficacy of Tissue Engineered Nerve Grafts |
2016 – 2017 |
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Emory Kuo, MD |
Medicine, PCOM |
Acute Neuroinflammatory Responses in TBI |
2015 – 2016 |
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Dmitriy Petrov*, MD |
Neurosurgery, UPenn |
Micro-Tissue Engineering Neural Networks to Restore Hippocampal Circuitry *Fellowship: Codman Neurotrauma & Critical Care |
2015 – 2016 |
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James Harris*, PhD |
Biomedical Engineering, Case Western Reserve |
Neurodegenerative and Neurophysiological Sequelae in TBI *Fellowship: NIH NRSA “Brain Injury Training Grant” |
2013 – 2015 |
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Joseph Frasca*, PhD |
Molecular Toxicology, Univ. of Rochester |
Alpha-Synuclein Mediated Pathophysiology in TBI *Fellowship: NIH NRSA “Brain Injury Training Grant” |
2012 – 2013 |
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John A. Wolf, PhD |
Neuroscience, UPenn |
Functional Reorganization of Limbic Circuitry After TBI in Swine |
2009 – 2011 |
Other lab alumni:
- Isha Patel
- Kammy Purpura
- Gabrielle Porter
- Asim Handy
- Srijan Kalva
- Eric Muthersbaugh
- Ronit Patel
- Adedotun Bello
- Andrés Garcia-Epelboim
- Sam Lien
- Olivia Rivellini
- Jerry Gao
- Shavon Coulter
- Annette Prah
- Natalia Fedorcza
- Nicholas Paleologos
- Kaila Helm
- Vishal Tian
- Halimulati Kaisaier
- Kate Panzer
- Joseph Maggiore
- Dan Brown, B.S.
- Sanford Roberts, B.A.
- Carla Winter
- Tina Lulla
- Carla Hernandez
- Ryan Zahalka
- Ellie Boyle
- Anthony Parisi
- Joseph Morand, B.S.
- Constance Mietus, B.A
- Matthew Weingard
- Scott Yerganian
- Janid Kiely
- Arshneel Kochar
- Billy Lane
- Jonathan Yu