Perelman School of Medicine at the University of Pennsylvania

Clinical Cell and Vaccine Production Facility (CVPF)

prep room

Publications - DC

T cell adoptive immunity for cancer | Gene-modified T cells for HIV | Dendritic cell vaccines for cancer | Reviews

Publication PMID PMCID
Fesnak AD, Hanley PJ, Levine BL. Considerations in T Cell Therapy Product Development for B CellLeukemia and Lymphoma Immunotherapy. Curr Hematol Malig Rep. 2017 Jul 31;1-9. doi: 10.1007/s11899-017-0395-9. PDF. Review.    
Levine BL, Miskin J, Wonnacott K, Keir C. Global Manufacturing of CAR T Cell Therapy. Mol Ther Methods Clin Dev.2016 Dec 31;4:92-101. doi: 10.1016/j.omtm.2016.12.006. eCollection 2017 Mar 17. Review. 28344995 PMC5363291
Fesnak AD, June CH, Levine BL. Engineered T cells: the promise and challenges of cancer immunotherapy. Nat Rev Cancer. 2016 Aug 23;16(9):566-81. DOI: 10.1038/nrc.2016.97. Review. 27550819  
Fesnak A, Lin C, Siegel DL, Maus MV. CAR-T Cell Therapies From the Transfusion Medicine Perspective. Transfus Med Rev. 2016 Jul;30(3):139-45. doi: 10.1016/j.tmrv.2016.03.001. Epub 2016 Mar 28. 27067907 PMC4914456
Maus MV, Levine BL. Chimeric Antigen Receptor T-Cell Therapy for the Community Oncologist.Oncologist.2016 May;21(5):608-17. doi: 10.1634/theoncologist.2015-0421. Epub 2016 Mar 23. Review. 27009942 PMC4861363
June CH, Levine BL. T cell engineering as therapy for cancer and HIV: our synthetic future. Philos Trans R Soc Lond B Biol Sci. 2015 Oct 19;370(1680):20140374. doi: 10.1098/rstb.2014.0374. Review. 26416683 PMC4634001
Levine BL. Performance-enhancing drugs: design and production of redirected chimeric antigen receptor (CAR) T cells. Cancer Gene Ther. 2015 Mar;22(2):79-84. DOI: 10.1038/cgt.2015.5. Epub 2015 Feb 13. Review. 25675873  
June CH, Maus MV, Plesa G, Johnson LA, Zhao Y, Levine BL, Grupp SA, Porter DL. Engineered T cells for cancer therapy. Cancer Immunol Immunother. 2014 Sep;63(9):969-75. DOI: 10.1007/s00262-014-1568-1. Epub 2014 Jun 19. Review. 24943274 PMC4142345
Melenhorst JJ, Levine BL. Innovation and opportunity for chimeric antigen receptor targeted T cells. Cytotherapy. 2013 Sep;15(9):1046-53. DOI: 10.1016/j.jcyt.2013.02.007. Epub 2013 Apr 2. Review. 23562306  
Paulos CM, Suhoski MM, Plesa G, Jiang T, Basu S, Golovina TN, Jiang S, Aqui NA, Powell DJ Jr, Levine BL, Carroll RG, Riley JL, June CH. Adoptive immunotherapy: good habits instilled at youth have long-term benefits. Immunol Res. 2008;42(1-3):182-96. DOI: 10.1007/s12026-008-8070-9. Review. 18949448 PMC3809041
Powell DJ, Levine BL. Adoptive T-cell therapy for malignant disorders. Haematologica. 2008 Oct;93(10):1452-6. DOI: 10.3324/haematol.13717. 18827263  
Levine, BL. T lymphocyte engineering ex vivo for cancer and infectious disease. Expert Opin Biol Ther. 2008 Apr;8(4):475-89. DOI: 10.1517/14712598.8.4.475. 18352851  
Manilla P, Rebello T, Afable C, Lu X, Slepushkin V, Humeau LM, Schonely K, Ni Y, Binder GK, Levine BL, Macgregor RR, June CH, Dropulic B. Regulatory Considerations for Novel Gene Therapy Products: A Review of the Process Leading to the First Clinical Lentiviral Vector. Hum Gene Ther. 2005 Jan;16(1):17-25. DOI: 10.1089/hum.2005.16.17. Review. 15703485