LAG-3 and PD-1 Synergize on CD8+ T Cells to Drive T-cell Exhaustion and Hinder Autocrine IFN-γ-dependent Anti-tumor Immunity

Andrews LP, Butler SC, Cui J, Cillo AR, Cardello C, Liu C, Brunazzi EA, Baessler A, Xie B, Kunning SR, Ngiow SF, Huang YJ, Manne S, Sharpe AH, Delgoffe GM, Wherry EJ, Kirkwood JM, Bruno TC, Workman CJ, Vignali DAA.

Cell. 2024 Aug 8;187(16):4355-4372.e22. PMID: 39121848