Proof That COVID Vaccines Work Is Easy to Find

President Trump recently questioned the effectiveness of COVID vaccines, but research demonstrates they continue to have a significant impact. Between late 2023 and August 2024, the vaccines prevented more than 107,000 hospitalizations and nearly 7,000 deaths in the United States. E. John Wherry, PhD, the Richard and Barbara Schiffrin President’s Distinguished Professor and chair of Systems Pharmacology and Translational Therapeutics, noted that although the most recent vaccines are about 45 percent effective against hospitalization, they still substantially reduce disease burden and health care costs.