Publications

Dec 2022

Inhibitory Siglec-sialic acid interactions in balancing immunological activation and tolerance during viral infections. Saini P, Adeniji OS, Abdel-Mohsen M. EBioMedicine. 2022 Dec;86:104354. doi: 10.1016/j.ebiom.2022.104354. Epub 2022 Nov 10. PMID: 36371982
Stereospecific antiseizure activity in mouse and rat epilepsy models by a pyridinium inhibitor of TNFα/NFκB signaling. Pollard BS, Wen Z, Jacobson KA, Pollard JR. Eur J Med Chem Rep. 2022 Dec;6:100065. doi: 10.1016/j.ejmcr.2022.100065. Epub 2022 Jun 8. PMID: 36003949
Chimeric antigen receptor T-cell therapy yields similar outcomes in patients with and without cytokine release syndrome. Bhaskar ST, Patel VG, Porter DL, Schuster SJ, Nastoupil LJ, Perales MA, Alarcon Tomas A, Bishop MR, McGuirk JP, Maziarz RT, Chen A, Bachanova V, Maakaron J, Riedell PA, Oluwole OO. Blood Adv. 2022 Dec 12:bloodadvances.2022008937. doi: 10.1182/bloodadvances.2022008937. Online ahead of print. PMID: 36508286
Expression of inducible factors reprograms CAR-T cells for enhanced function and safety. Smole A, Benton A, Poussin MA, Eiva MA, Mezzanotte C, Camisa B, Greco B, Sharma P, Minutolo NG, Gray F, Bear AS, Baroja ML, Cummins C, Xu C, Sanvito F, Goldgewicht AL, Blanchard T, Rodriguez-Garcia A, Klichinsky M, Bonini C, June CH, Posey AD Jr, Linette GP, Carreno BM, Casucci M, Powell DJ Jr. Cancer Cell. 2022 Dec 12;40(12):1470-1487.e7. doi: 10.1016/j.ccell.2022.11.006. PMID: 36513049
Aedes aegypti Malpighian tubules are immunologically activated following systemic Toll activation. Sneed SD, Dwivedi SB, DiGate C, Denecke S, Povelones M. Parasit Vectors. 2022 Dec 15;15(1):469. doi: 10.1186/s13071-022-05567-2. PMID: 36522779
Monitoring Therapeutic Response to Anti-FAP CAR T Cells Using [18F]AlF-FAPI-74. Lee IK, Noguera-Ortega E, Xiao Z, Todd L, Scholler J, Song D, Liousia M, Lohith K, Xu K, Edwards KJ, Farwell MD, June CH, Albelda SM, Puré E, Sellmyer MA. Clin Cancer Res. 2022 Dec 15;28(24):5330-5342. doi: 10.1158/1078-0432.CCR-22-1379. PMID: 35972732

Nov 2022

Human galectin-9 promotes the expansion of HIV reservoirs in vivo in humanized mice. Yuan Z, Giron LB, Hart C, Gyampoh A, Koshy J, Hong KY, Niki T, Premeaux TA, Ndhlovu LC, Deleage C, Montaner LJ, Abdel-Mohsen M. AIDS 2022 Nov 28. Online ahead of print. PMID: 36460646
HIV-1 Vpu restricts Fc-mediated effector functions in vivo. Prévost J, Anand SP, Rajashekar JK, Zhu L, Richard J, Goyette G, Medjahed H, Gendron-Lepage G, Chen HC, Chen Y, Horwitz JA, Grunst MW, Zolla-Pazner S, Haynes BF, Burton DR, Flavell RA, Kirchhoff F, Hahn BH, Smith AB 3rd, Pazgier M, Nussenzweig MC, Kumar P, Finzi A. Cell Rep. 2022 Nov 8;41(6):111624. doi: 10.1016/j.celrep.2022.111624. PMID: 36351384
Evasion of cGAS and TRIM5 defines pandemic HIV. Zuliani-Alvarez L, Govasli ML, Rasaiyaah J, Monit C, Perry SO, Sumner RP, McAlpine-Scott S, Dickson C, Rifat Faysal KM, Hilditch L, Miles RJ, Bibollet-Ruche F, Hahn BH, Boecking T, Pinotsis N, James LC, Jacques DA, Towers GJ. Nat Microbiol. 2022 Nov;7(11):1762-1776. doi: 10.1038/s41564-022-01247-0. Epub 2022 Oct 26. PMID: 36289397
"Visualization" of pain using cerebral ¹⁸F-FDG PET/CT following surgical treatment of lumbar disc herniation. Støttrup CC, Mortensen CH, Piri R, Khosravi M, Newberg A, Andersen MØ, Alavi A, Grupe P, Høilund-Carlsen PF. Eur Spine J. 2022 Nov 13. doi: 10.1007/s00586-022-07442-1. Online ahead of print.PMID: 36371750
The Selective Estrogen Receptor Modulator, Raloxifene, Is Protective Against Renal Ischemia-reperfusion Injury. Hernandez P, O'Brien C, Concors SJ, Wang Z, Ge G, Hancock WW, Levine MH. Transplantation. 2022 Nov 1;106(11):2166-2171. doi: 10.1097/TP.0000000000004194. Epub 2022 Oct 21. PMID: 35655356
Pre-clinical investigation of astatine-211-parthanatine for high-risk neuroblastoma. Makvandi M, Samanta M, Martorano P, Lee H, Gitto SB, Patel K, Groff D, Pogoriler J, Martinez D, Riad A, Dabagian H, Zaleski M, Taghvaee T, Xu K, Lee JY, Hou C, Farrel A, Batra V, Carlin SD, Powell DJ Jr, Mach RH, Pryma DA, Maris JM. Commun Biol. 2022 Nov 17;5(1):1260. doi: 10.1038/s42003-022-04209-8. PMID: 36396952

Oct 2022

A boost with SARS-CoV-2 BNT162b2 mRNA vaccine elicits strong humoral responses independently of the interval between the first two doses. Tauzin A, Gong SY, Chatterjee D, Ding S, Painter MM, Goel RR, Beaudoin-Bussières G, Marchitto L, Boutin M, Laumaea A, Okeny J, Gendron-Lepage G, Bourassa C, Medjahed H, Goyette G, Williams JC, Bo Y, Gokool L, Morrisseau C, Arlotto P, Bazin R, Fafard J, Tremblay C, Kaufmann DE, De Serres G, Richard J, Côté M, Duerr R, Martel-Laferrière V, Greenplate AR, Wherry EJ, Finzi A. Cell Rep. 2022 Oct 5:111554. doi: 10.1016/j.celrep.2022.111554. Online ahead of print. PMID: 36244343
SARS-CoV-2 infections elicit higher levels of original antigenic sin antibodies compared with SARS-CoV-2 mRNA vaccinations. Anderson EM, Li SH, Awofolaju M, Eilola T, Goodwin E, Bolton MJ, Gouma S, Manzoni TB, Hicks P, Goel RR, Painter MM, Apostolidis SA, Mathew D, Dunbar D, Fiore D, Brock A, Weaver J, Millar JS, DerOhannessian S; UPenn COVID Processing Unit, Greenplate AR, Frank I, Rader DJ, Wherry EJ, Bates P, Hensley SE. Cell Rep. 2022 Oct 18;41(3):111496. doi: 10.1016/j.celrep.2022.111496. PMID: 36261003
Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics. Giles JR, Ngiow SF, Manne S, Baxter AE, Khan O, Wang P, Staupe R, Abdel-Hakeem MS, Huang H, Mathew D, Painter MM, Wu JE, Huang YJ, Goel RR, Yan PK, Karakousis GC, Xu X, Mitchell TC, Huang AC, Wherry EJ. Nat Immunol. 2022 Oct 21. doi: 10.1038/s41590-022-01338-4. Online ahead of print. PMID: 36271148
PPT1 inhibition enhances the antitumor activity of anti-PD-1 antibody in melanoma. Sharma G, Ojha R, Noguera-Ortega E, Rebecca VW, Attanasio J, Liu S, Piao S, Lee JJ, Nicastri MC, Harper SL, Ronghe A, Jain V, Winkler JD, Speicher DW, Mastio J, Gimotty PA, Xu X, Wherry EJ, Gabrilovich DI, Amaravadi RK. JCI Insight. 2022 Oct 24;7(20):e165688. doi: 10.1172/jci.insight.165688. PMID: 36278493
Assessing Coronary Artery and Aortic Calcification in Patients with Prostate Cancer Using 18F-Sodium Fluoride PET/Computed Tomography. Raynor WY, Borja AJ, Zhang V, Kothekar E, Lau HC, Ng SJ, Seraj SM, Rojulpote C, Taghvaei R, Jin KY, Werner TJ, Høilund-Carlsen PF, Alavi A, Revheim ME. PET Clin. 2022 Oct;17(4):653-659. doi: 10.1016/j.cpet.2022.07.009. PMID: 36229106
Feasibility of Global Assessment of Bone Metastases in Prostate Cancer with 18F-Sodium Fluoride-PET/Computed Tomography. Koa B, Raynor WY, Park PSU, Borja AJ, Singhal S, Kuang A, Zhang V, Werner TJ, Alavi A, Revheim ME. PET Clin. 2022 Oct;17(4):631-640. doi: 10.1016/j.cpet.2022.07.007. PMID: 36229105
Methadone use is associated with increased levels of sCD14, immune activation, and inflammation during suppressed HIV infection. Azzoni L, Giron LB, Vadrevu S, Zhao L, Lalley-Chareczko L, Hiserodt E, Fair M, Lynn K, Trooskin S, Mounzer K, Abdel-Mohsen M, Montaner LJ. J Leukoc Biol. 2022 Oct;112(4):733-744. doi: 10.1002/JLB.4A1221-678RR. Epub 2022 Aug 2. PMID: 35916053
Whole-Brain Perfusion via Right Common Carotid Artery With Type 2 Proatlantal Intersegmental Artery. Zuflacht JP, Liang C, Burkhardt JK, Favilla CG. Stroke. 2022 Aug 12:101161STROKEAHA122040239. doi: 10.1161/STROKEAHA.122.040239. Online ahead of print. PMID: 35959680
National Survey on Flow-Diverting Stents for Intracranial Aneurysms in the United States. Salem MM, Elfil M, Aboutaleb PE, Dmytriw AA, Thomas AJ, Hassan AE, Mascitelli JR, Kan P, Jankowitz BT, Burkhardt JK. World Neurosurg. 2022 Oct;166:e958-e967. doi: 10.1016/j.wneu.2022.07.144. Epub 2022 Aug 8. PMID: 35953041
Alterations in the respiratory tract microbiome in COVID-19: current observations and potential significance. Merenstein C, Bushman FD, Collman RG. Microbiome. 2022 Oct 5;10(1):165. doi: 10.1186/s40168-022-01342-8. PMID: 36195943
Author Correction: Long-term safety and efficacy of lentiviral hematopoietic stem/progenitor cell gene therapy for Wiskott-Aldrich syndrome. Magnani A, Semeraro M, Adam F, Booth C, Dupré L, Morris EC, Gabrion A, Roudaut C, Borgel D, Toubert A, Clave E, Abdo C, Gorochov G, Petermann R, Guiot M, Miyara M, Moshous D, Magrin E, Denis A, Suarez F, Lagresle C, Roche AM, Everett J, Trinquand A, Guisset M, Bayford JX, Hacein-Bey-Abina S, Kauskot A, Elfeky R, Rivat C, Abbas S, Gaspar HB, Macintyre E, Picard C, Bushman FD, Galy A, Fischer A, Six E, Thrasher AJ, Cavazzana M. Nat Med. 2022 Oct;28(10):2217. doi: 10.1038/s41591-022-01985-y. PMID: 35945284
Protection of regulatory T cells from fragility and inactivation in the tumor microenvironment. Zhang H, Tomar VS, Li J, Basavaraja R, Yan F, Gui J, McBrearty N, Costich TL, Beiting DP, Blanco MA, Nefedova Y, Conejo-Garcia JR, Saggu G, Berger AJ, Gabrilovich DI, Fuchs SY. Cancer Immunol Res. 2022 Oct 18:CIR-22-0295. doi: 10.1158/2326-6066.CIR-22-0295. Online ahead of print. PMID: 36255418
The lncRNA ALPHA specifically targets chikungunya virus to control infection. Basavappa MG, Ferretti M, Dittmar M, Stoute J, Sullivan MC, Whig K, Shen H, Liu KF, Schultz DC, Beiting DP, Lynch KW, Henao-Mejia J, Cherry S. Mol Cell. 2022 Oct 6;82(19):3729-3744.e10. doi: 10.1016/j.molcel.2022.08.030. Epub 2022 Sep 26. PMID: 36167073
Single-cell transcriptomics reveals skewed cellular communication and phenotypic shift in pulmonary artery remodeling. Crnkovic S, Valzano F, Fließer E, Gindlhuber J, Thekkekara Puthenparampil H, Basil M, Morley MP, Katzen J, Gschwandtner E, Klepetko W, Cantu E, Wolinski H, Olschewski H, Lindenmann J, Zhao YY, Morrisey EE, Marsh LM, Kwapiszewska G. JCI Insight. 2022 Oct 24;7(20):e153471. doi: 10.1172/jci.insight.153471. PMID: 36099047
Epidemiology, risk factors, and outcomes of lung retransplantation: An analysis of the International Society for Heart and Lung Transplantation Thoracic Transplant Registry. Harhay MO, Cherikh WS, Toll AE, Christie JD, Stehlik J, Chambers D, Hayes D Jr, Cantu E. J Heart Lung Transplant. 2022 Oct;41(10):1478-1486. doi: 10.1016/j.healun.2022.06.022. Epub 2022 Jul 5. PMID: 35933297
TEMPOL inhibits SARS-CoV-2 replication and development of lung disease in the Syrian hamster model. Maio N, Cherry S, Schultz DC, Hurst BL, Linehan WM, Rouault TA. iScience. 2022 Oct 21;25(10):105074. doi: 10.1016/j.isci.2022.105074. Epub 2022 Sep 6. PMID: 36093377
Modulation of BCL-2 in Both T Cells and Tumor Cells to Enhance Chimeric Antigen Receptor T-cell Immunotherapy against Cancer. Lee YG, Guruprasad P, Ghilardi G, Pajarillo R, Sauter CT, Patel R, Ballard HJ, Hong SJ, Chun I, Yang N, Amelsberg KV, Cummins KD, Svoboda J, Gill S, Chong EA, North K, Church SE, Fraietta JA, Chang WJ, Lacey SF, Lu XM, Zhang Y, Whig K, Schultz DC, Cherry S, Gerson J, Schuster SJ, Porazzi P, Ruella M. Cancer Discov. 2022 Oct 5;12(10):2372-2391. doi: 10.1158/2159-8290.CD-21-1026. PMID: 35904479
Neutrophils in the periodontium: Interactions with pathogens and roles in tissue homeostasis and inflammation. Uriarte SM, Hajishengallis G. Immunol Rev. 2022 Oct 22. doi: 10.1111/imr.13152. Online ahead of print. PMID: 36271881
The role of neutrophils in trained immunity. Kalafati L, Hatzioannou A, Hajishengallis G, Chavakis T. Immunol Rev. 2022 Oct 3. doi: 10.1111/imr.13142. Online ahead of print. PMID: 36190144
Complement Is Required for Microbe-Driven Induction of Th17 and Periodontitis. Wang H, Ideguchi H, Kajikawa T, Mastellos DC, Lambris JD, Hajishengallis G. J Immunol. 2022 Oct 1;209(7):1370-1378. doi: 10.4049/jimmunol.2200338. Epub 2022 Aug 26. PMID: 36028293
Dll1-Mediated Notch Signaling Drives Tumor Cell Cross-talk with Cancer-Associated Fibroblasts to Promote Radioresistance in Breast Cancer. Nandi A, Debnath R, Nayak A, To TKJ, Thacker G, Reilly M, Gumber S, Karagounis I, Li N, Lengner CJ, Haldar M, Welm AL, Blanco AM, Thomas C, Chakrabarti R. Cancer Res. 2022 Oct 17;82(20):3718-3733. doi: 10.1158/0008-5472.CAN-21-1225.PMID: 36007109
Multiple health-related behaviours among Fly-In Fly-Out workers in the mining industry in Australia: A cross-sectional survey during the COVID-19 pandemic. Asare BY, Thomas E, Affandi JS, Schammer M, Harris C, Kwasnicka D, Powell D, Reid CM, Robinson S. PLoS One. 2022 Oct 27;17(10):e0275008. doi: 10.1371/journal.pone.0275008. eCollection 2022. PMID: 36301801
GRK2 inhibitors, paroxetine and CCG258747, attenuate IgE-mediated anaphylaxis but activate mast cells via MRGPRX2 and MRGPRB2. Thapaliya M, Amponnawarat A, Tesmer JJG, Ali H. Front Immunol. 2022 Oct 6;13:1032497. doi: 10.3389/fimmu.2022.1032497. eCollection 2022.PMID: 36275707

Sept 2022

Building effective collaborations for the study of COVID-19 across the severity spectrum. Agyekum RS, Abramoff BA, Wherry EJ, Meyer NJ. Nat Immunol. 2022 Sep;23(9):1287-1290. doi: 10.1038/s41590-022-01283-2. PMID: 35999396
Atherosclerosis Burdens in Diabetes Mellitus: Assessment by PET Imaging. Høilund-Carlsen PF, Piri R, Madsen PL, Revheim ME, Werner TJ, Alavi A, Gerke O, Sturek M. Int J Mol Sci. 2022 Sep 6;23(18):10268. doi: 10.3390/ijms231810268. PMID: 36142181
Association of Apremilast With Vascular Inflammation and Cardiometabolic Function in Patients With Psoriasis: The VIP-A Phase 4, Open-label, Nonrandomized Clinical Trial. Gelfand JM, Shin DB, Armstrong AW, Tyring SK, Blauvelt A, Gottlieb S, Lockshin BN, Kalb RE, Fitzsimmons R, Rodante J, Parel P, Manyak GA, Mendelsohn L, Noe MH, Papadopoulos M, Syed MN, Werner TJ, Wan J, Playford MP, Alavi A, Mehta NN. JAMA Dermatol. 2022 Sep 21:e223862. doi: 10.1001/jamadermatol.2022.3862. Online ahead of print. PMID: 36129688
Monitoring the Progression of a Calcifying Uterine Leiomyoma: Detection Using 18F-NaF-PET/CT. Resto DA, Park PSU, Werner TJ, Høilund-Carlsen PF, Alavi A. Clin Nucl Med. 2022 Sep 21. doi: 10.1097/RLU.0000000000004395. Online ahead of print. PMID: 36127774
Markers of fungal translocation are elevated during post-acute sequelae of SARS-CoV-2 and induce NF-κB signaling. Giron LB, Peluso MJ, Ding J, Kenny G, Zilberstein NF, Koshy J, Hong KY, Rasmussen H, Miller GE, Bishehsari F, Balk RA, Moy JN, Hoh R, Lu S, Goldman AR, Tang HY, Yee BC, Chenna A, Winslow JW, Petropoulos CJ, Kelly JD, Wasse H, Martin JN, Liu Q, Keshavarzian A, Landay A, Deeks SG, Henrich TJ, Abdel-Mohsen M. JCI Insight. 2022 Sep 22;7(18):e164813. doi: 10.1172/jci.insight.164813.
PMID: 36134654
The microbiome-derived metabolite TMAO drives immune activation and boosts responses to immune checkpoint blockade in pancreatic cancer. Mirji G, Worth A, Bhat SA, El Sayed M, Kannan T, Goldman AR, Tang HY, Liu Q, Auslander N, Dang CV, Abdel-Mohsen M, Kossenkov A, Stanger BZ, Shinde RS. Sci Immunol. 2022 Sep 9;7(75):eabn0704. doi: 10.1126/sciimmunol.abn0704. Epub 2022 Sep 9. PMID: 36083892
The Lung Allograft Microbiome Associates with Pepsin, Inflammation, and Primary Graft Dysfunction. McGinniss JE, Whiteside SA, Deek RA, Simon-Soro A, Graham-Wooten J, Oyster M, Brown MD, Cantu E, Diamond JM, Li H, Christie JD, Bushman FD, Collman RG. Am J Respir Crit Care Med. 2022 Sep 14. doi: 10.1164/rccm.202112-2786OC. Online ahead of print. PMID: 36103583
Debulking different Corona (SARS-CoV-2 delta, omicron, OC43) and Influenza (H1N1, H3N2) virus strains by plant viral trap proteins in chewing gums to decrease infection and transmission. Daniell H, Nair SK, Guan H, Guo Y, Kulchar RJ, Torres MDT, Shahed-Al-Mahmud M, Wakade G, Liu YM, Marques AD, Graham-Wooten J, Zhou W, Wang P, Molugu SK, de Araujo WR, de la Fuente-Nunez C, Ma C, Short WR, Tebas P, Margulies KB, Bushman FD, Mante FK, Ricciardi RP, Collman RG, Wolff MS. Biomaterials. 2022 Sep;288:121671. doi: 10.1016/j.biomaterials.2022.121671. Epub 2022 Jul 18. PMID: 35953331
Altered adipose tissue macrophage populations in people with HIV on integrase inhibitor-containing antiretroviral therapy. Vakili S, Paneru B, Guerrier CM, Miller J, Baumrin E, Forrestel A, Lynn K, Frank I, Lo Re V 3rd, Collman RG, Hill DA. AIDS. 2022 Sep 1;36(11):1493-1500. doi: 10.1097/QAD.0000000000003278. Epub 2022 Jul 8. PMID: 35848549
ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes. Lu Z, McBrearty N, Chen J, Tomar VS, Zhang H, De Rosa G, Tan A, Weljie AM, Beiting DP, Miao Z, George SS, Berger A, Saggu G, Diehl JA, Koumenis C, Fuchs SY. Cell Metab. 2022 Sep 6;34(9):1342-1358.e7. doi: 10.1016/j.cmet.2022.08.007. PMID: 36070682
Defining and targeting patterns of T cell dysfunction in inborn errors of immunity. Campos JS, Henrickson SE. Front Immunol. 2022 Sep 14;13:932715. doi: 10.3389/fimmu.2022.932715. eCollection 2022. PMID: 36189259

August 2022

The effects of limb laterality and age on the inflammation and bone turnover of the acromioclavicular shoulder joint: 18 F-fluorodeoxyglucose and 18 F-sodium-fluoride-PET/computed tomography study. Park PSU, McDonald E, Singh SB, Raynor WY, Werner TJ, Høilund-Carlsen PF, Alavi A. Nucl Med Commun. 2022 Aug 1;43(8):922-927. doi: 10.1097/MNM.0000000000001588. Epub 2022 May 30. PMID: 35634806
The Pennsylvania Postmarket Multicenter Experience With Flow Redirection Endoluminal Device. Salem MM, Kvint S, Hendrix P, Al Saiegh F, Gajjar AA, Choudhri O, Jankowitz BT, Goren O, Gross BA, Jabbour P, Lang M, Schirmer CM, Tjoumakaris SI, Griessenauer CJ, Burkhardt JK. Neurosurgery. 2022 Aug 1;91(2):280-285. doi: 10.1227/neu.0000000000001970. Epub 2022 Apr 12. PMID: 35394453
HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription. Huang P, Peslak SA, Ren R, Khandros E, Qin K, Keller CA, Giardine B, Bell HW, Lan X, Sharma M, Horton JR, Abdulmalik O, Chou ST, Shi J, Crossley M, Hardison RC, Cheng X, Blobel GA. Nat Genet. 2022 Aug 8. doi: 10.1038/s41588-022-01152-6. Online ahead of print. PMID: 35941187
Targeting the EIF2AK1 signaling pathway rescues red blood cell production in SF3B1-mutant myelodysplastic syndromes with ringed sideroblasts. Adema V, Ma F, Kanagal-Shamanna R, Thongon N, Montalban-Bravo G, Yang H, Peslak SA, Wang F, Acha P, Sole F, Lockyer P, Cassari M, Maciejewski JP, Visconte V, Ganan-Gomez I, Song Y, Bueso-Ramos C, Pellegrini M, Tan TM, Bejar R, Carew JS, Halene S, Santini V, Al-Atrash G, Clise-Dwyer K, Garcia-Manero G, Blobel GA, Colla S. Blood Cancer Discov. 2022 Aug 4:BCD-21-0220. doi: 10.1158/2643-3230.BCD-21-0220. Online ahead of print. PMID: 35926182
T-bet B or not T-bet B, is that the question in obesity-related metabolic disease? Cancro MP.Cell Metab. 2022 Aug 2;34(8):1081-1082. doi: 10.1016/j.cmet.2022.07.008.PMID: 35921814
Platelets get particular . Rauova L, Cines DB. Blood. 2022 Aug 4;140(5):413-414. doi: 10.1182/blood.2022016773. PMID: 35925641
Renally Excretable Silver Telluride Nanoparticles as Contrast Agents for X-ray Imaging . Nieves LM, Dong YC, Rosario-Berríos DN, Mossburg K, Hsu JC, Cramer GM, Busch TM, Maidment ADA, Cormode DP. ACS Appl Mater Interfaces. 2022 Aug 3;14(30):34354-34364. doi: 10.1021/acsami.2c06190. Epub 2022 Jul 22. PMID: 35867906
Gardnerella vaginalis alters cervicovaginal epithelial cell function through microbe-specific immune responses. Anton L, Ferguson B, Friedman ES, Gerson KD, Brown AG, Elovitz MA. Microbiome. 2022 Aug 4;10(1):119. doi: 10.1186/s40168-022-01317-9. PMID: 35922830
Gardnerella vaginalis induces matrix metalloproteinases in the cervicovaginal epithelium through TLR-2 activation . Gerson KD, Anton L, Ferguson B, Ravel J, Burris HH, Elovitz MA. J Reprod Immunol. 2022 Aug;152:103648. doi: 10.1016/j.jri.2022.103648. Epub 2022 May 23 .PMID: 35679790
Oncolytic Myxoma virus infects and damages the tegument of the human parasitic flatworm Schistosoma mansoni. Rahman MM, McFadden G, Ruthel G, Herbert DR, Freedman BD, Greenberg RM, Bais S. Exp Parasitol. 2022 Aug;239:108263. doi: 10.1016/j.exppara.2022.108263. Epub 2022 May 19. PMID: 35598646
Diagnostic Yield of Cone-beam-Derived Augmented Fluoroscopy and Ultrathin Bronchoscopy Versus Conventional Navigational Bronchoscopy Techniques. DiBardino DM, Kim RY, Cao Y, Andronov M, Lanfranco AR, Haas AR, Vachani A, Ma KC, Hutchinson CT. J Bronchology Interv Pulmonol. 2022 Aug 3. doi: 10.1097/LBR.0000000000000883. Online ahead of print. PMID: 35920067
The role of sex in exhaustion. Henrickson SE. Sci Immunol. 2022 Aug 5;7(74):eade1495. doi: 10.1126/sciimmunol.ade1495. Epub 2022 Aug 5. PMID: 35930655
PD-1 directed immunotherapy alters Tfh and humoral immune responses to seasonal influenza vaccine . Herati RS, Knorr DA, Vella LA, Silva LV, Chilukuri L, Apostolidis SA, Huang AC, Muselman A, Manne S, Kuthuru O, Staupe RP, Adamski SA, Kannan S, Kurupati RK, Ertl HCJ, Wong JL, Bournazos S, McGettigan S, Schuchter LM, Kotecha RR, Funt SA, Voss MH, Motzer RJ, Lee CH, Bajorin DF, Mitchell TC, Ravetch JV, Wherry EJ. Nat Immunol. 2022 Aug;23(8):1183-1192. doi: 10.1038/s41590-022-01274-3. Epub 2022 Jul 28. PMID: 35902637
Multicenter assessment of augmented reality registration methods for image-guided interventions. Li N, Wakim J, Koethe Y, Huber T, Schenning R, Gade TP, Hunt SJ, Park BJ. Radiol Med. 2022 Aug;127(8):857-865. doi: 10.1007/s11547-022-01515-3. Epub 2022 Jun 23. PMID: 35737194
Preintervention Computed Tomography Improves the Performance of Endovascular Intervention in Patients with Abdominopelvic Trauma. McGraw JR, Cannon JW, Nadolski GJ, Hunt SJ, Clark TWI, Gade TPF. J Vasc Interv Radiol. 2022 Aug;33(8):979-986. doi: 10.1016/j.jvir.2022.05.006. Epub 2022 May 19. PMID: 35598852
High-Pressure Synthesis and Physical Properties of a Spinel Compound FeAl₂S₄. Duan L, Wang X, Zhao J, Zhang J, Du S, Feng Y, Zhao Z, Wang S, Jin C. Inorg Chem. 2022 Aug 9. doi: 10.1021/acs.inorgchem.2c02034. Online ahead of print. PMID: 35943140
T cell immunity to COVID-19 vaccines. Wherry EJ, Barouch DH. Science. 2022 Aug 19;377(6608):821-822. doi: 10.1126/science.add2897. Epub 2022 Aug 18. PMID: 35981045
Correction for Merenstein et al., "Signatures of COVID-19 Severity and Immune Response in the Respiratory Tract Microbiome". Merenstein C, Liang G, Whiteside SA, Cobián-Güemes AG, Merlino MS, Taylor LJ, Glascock A, Bittinger K, Tanes C, Graham-Wooten J, Khatib LA, Fitzgerald AS, Reddy S, Baxter AE, Giles JR, Oldridge DA, Meyer NJ, Wherry EJ, McGinniss JE, Bushman FD, Collman RG. mBio. 2022 Aug 31:e0229322. doi: 10.1128/mbio.02293-22. Online ahead of print. PMID: 36043873
Markers of fungal translocation are elevated during post-acute sequelae of SARS-CoV-2 and induce NF-κB signaling. Giron LB, Peluso MJ, Ding J, Kenny G, Zilberstein NF, Koshy J, Hong KY, Rasmussen H, Miller GE, Bishehsari F, Balk RA, Moy JN, Hoh R, Lu S, Goldman AR, Tang HY, Yee BC, Chenna A, Winslow JW, Petropoulos CJ, Kelly JD, Wasse H, Martin JN, Liu Q, Keshavarzian A, Landay A, Deeks SG, Henrich TJ, Abdel-Mohsen M. JCI Insight. 2022 Aug 8;7(15):e160989. doi: 10.1172/jci.insight.160989.
PMID: 35727635
COManeci MechANical dilation for vasospasm (COMMAND): multicenter experience. Salem MM, Khalife J, Desai S, Sharashidze V, Badger C, Kuhn AL, Monteiro A, Salahuddin H, Siddiqui AH, Singh J, Levy EI, Lang M, Grandhi R, Thomas AJ, Lin LM, Tanweer O, Burkhardt JK, Puri AS, Gross BA, Nossek E, Hassan AE, Shaikh HA, Jankowitz BT. J Neurointerv Surg. 2022 Aug 24:jnis-2022-019272. doi: 10.1136/jnis-2022-019272. Online ahead of print. PMID: 36002289
Position-Specific Secondary Acylation Determines Detection of Lipid A by Murine TLR4 and Caspase-11. Harberts EM, Grubaugh D, Akuma DC, Shin S, Ernst RK, Brodsky IE. Infect Immun. 2022 Aug 18;90(8):e0020122. doi: 10.1128/iai.00201-22. Epub 2022 Jul 14. PMID: 35862717
Lipid A Variants Activate Human TLR4 and the Noncanonical Inflammasome Differently and Require the Core Oligosaccharide for Inflammasome Activation. Alexander-Floyd J, Bass AR, Harberts EM, Grubaugh D, Buxbaum JD, Brodsky IE, Ernst RK, Shin S. Infect Immun. 2022 Aug 18;90(8):e0020822. doi: 10.1128/iai.00208-22. Epub 2022 Jul 14. PMID: 35862709
Multiple Introductions of SARS-CoV-2 Alpha and Delta Variants into White-Tailed Deer in Pennsylvania. Marques AD, Sherrill-Mix S, Everett JK, Adhikari H, Reddy S, Ellis JC, Zeliff H, Greening SS, Cannuscio CC, Strelau KM, Collman RG, Kelly BJ, Rodino KG, Bushman FD, Gagne RB, Anis E. mBio. 2022 Aug 24:e0210122. doi: 10.1128/mbio.02101-22. Online ahead of print. PMID: 36000731
The enigmatic roles of Anelloviridae and Redondoviridae in humans. Taylor LJ, Keeler EL, Bushman FD, Collman RG. Curr Opin Virol. 2022 Aug;55:101248. doi: 10.1016/j.coviro.2022.101248. Epub 2022 Jul 20. PMID: 35870315
Evaluating the state of the science for adeno-associated virus integration: An integrated perspective. Sabatino DE, Bushman FD, Chandler RJ, Crystal RG, Davidson BL, Dolmetsch R, Eggan KC, Gao G, Gil-Farina I, Kay MA, McCarty DM, Montini E, Ndu A, Yuan J; American Society of Gene and Cell Therapy (ASGCT) Working Group on AAV Integration. Mol Ther. 2022 Aug 3;30(8):2646-2663. doi: 10.1016/j.ymthe.2022.06.004. Epub 2022 Jun 10. PMID: 35690906
T-bet B or not T-bet B, is that the question in obesity-related metabolic disease? Cancro MP. Cell Metab. 2022 Aug 2;34(8):1081-1082. doi: 10.1016/j.cmet.2022.07.008. PMID: 35921814
Contemporary trends in PGD incidence, outcomes, and therapies. Cantu E, Diamond JM, Cevasco M, Suzuki Y, Crespo M, Clausen E, Dallara L, Ramon CV, Harmon MT, Bermudez C, Benvenuto L, Anderson M, Wille KM, Weinacker A, Dhillon GS, Orens J, Shah P, Merlo C, Lama V, McDyer J, Snyder L, Palmer S, Hartwig M, Hage CA, Singer J, Calfee C, Kukreja J, Greenland JR, Ware LB, Localio R, Hsu J, Gallop R, Christie JD. J Heart Lung Transplant. 2022 Aug 31:S1053-2498(22)02080-0. doi: 10.1016/j.healun.2022.08.013. Online ahead of print. PMID: 36216694
Clinical impact of a modified lung allocation score that mitigates selection bias. Schnellinger EM, Cantu E, Schaubel DE, Kimmel SE, Stephens-Shields AJ. J Heart Lung Transplant. 2022 Aug 7:S1053-2498(22)02068-X. doi: 10.1016/j.healun.2022.08.003. Online ahead of print. PMID: 36064649
A Conceptual Model for Sources of Differential Selection in Lung Transplant Allocation. Schnellinger EM, Cantu E, Kimmel SE, Szymczak JE. Ann Am Thorac Soc. 2022 Aug 31. doi: 10.1513/AnnalsATS.202202-105OC. Online ahead of print. PMID: 36044711
Changes in Circulating Tumor DNA Reflect Clinical Benefit Across Multiple Studies of Patients With Non-Small-Cell Lung Cancer Treated With Immune Checkpoint Inhibitors. Vega DM, Nishimura KK, Zariffa N, Thompson JC, Hoering A, Cilento V, Rosenthal A, Anagnostou V, Baden J, Beaver JA, Chaudhuri AA, Chudova D, Fine AD, Fiore J, Hodge R, Hodgson D, Hunkapiller N, Klass DM, Kobie J, Peña C, Pennello G, Peterman N, Philip R, Quinn KJ, Raben D, Rosner GL, Sausen M, Tezcan A, Xia Q, Yi J, Young AG, Stewart MD, Carpenter EL, Aggarwal C, Allen J. JCO Precis Oncol. 2022 Aug;6:e2100372. doi: 10.1200/PO.21.00372. PMID: 35952319
Leishmania amazonensis sabotages host cell SUMOylation for intracellular survival. Okuda K, Silva Costa Franco MM, Yasunaga A, Gazzinelli R, Rabinovitch M, Cherry S, Silverman N. iScience. 2022 Aug 13;25(9):104909. doi: 10.1016/j.isci.2022.104909. eCollection 2022 Sep 16. PMID: 36060064
The role of sex in exhaustion. Henrickson SE. Sci Immunol. 2022 Aug 5;7(74):eade1495. doi: 10.1126/sciimmunol.ade1495. Epub 2022 Aug 5. PMID: 35930655

July 2022

Single-cell glycomics analysis by CyTOF-Lec reveals glycan features defining cells differentially susceptible to HIV. Ma T, McGregor M, Giron L, Xie G, George AF, Abdel-Mohsen M, Roan NR.Elife. 2022 Jul 5;11:e78870. doi: 10.7554/eLife.78870. PMID: 35787792
Volumetric parameters from [¹⁸ F]FDG PET/CT predicts survival in patients with high-grade gastroenteropancreatic neuroendocrine neoplasms. Langen Stokmo H, Aly M, Bowitz Lothe IM, Borja AJ, Mehdizadeh Seraj S, Ghorpade R, Miao X, Hjortland GO, Malinen E, Sorbye H, Werner TJ, Alavi A, Revheim ME. J Neuroendocrinol. 2022 Jul;34(7):e13170. doi: 10.1111/jne.13170. Epub 2022 Jun 21. PMID: 35729738
Fluorodeoxyglucose versus Non-Fluorodeoxyglucose PET-Computed Tomography in Less-Explored Domains: An Appraisal. Basu S, Kumar R, Alavi A. PET Clin. 2022 Jul;17(3):xv-xvi. doi: 10.1016/j.cpet.2022.05.001. PMID: 35717107
Fluorodeoxyglucose PET/Computed Tomography in Evaluation of Prosthetic Joints and Diabetic Foot: A Comparative Perspective with Other Functional Imaging Modalities. Rachh SS, Basu S, Alavi A. PET Clin. 2022 Jul;17(3):517-531. doi: 10.1016/j.cpet.2022.02.002. PMID: 35717105
Positron Emission Tomography-Based Assessment of Cognitive Impairment and Dementias, Critical Role of Fluorodeoxyglucose in such Settings. Newberg AB, Coble R, Khosravi M, Alavi A. PET Clin. 2022 Jul;17(3):479-494. doi: 10.1016/j.cpet.2022.03.009. PMID: 35717103
18F-FDG Versus Non-FDG PET Tracers in Multiple Myeloma. Hemrom A, Tupalli A, Alavi A, Kumar R. PET Clin. 2022 Jul;17(3):415-430. doi: 10.1016/j.cpet.2022.03.001. PMID: 35717100
Molecular Imaging Assessment of Hormonally Sensitive Breast Cancer: An Appraisal of 2-[18F]-Fluoro-2-Deoxy-Glucose and Newer Non-2-[18F]-Fluoro-2-Deoxy-Glucose PET Tracers. Yadav D, Kumar R, Phulia A, Basu S, Alavi A. PET Clin. 2022 Jul;17(3):399-413. doi: 10.1016/j.cpet.2022.04.001. PMID: 35717099
Facts and Fictions About [18F]FDG versus Other Tracers in Managing Patients with Brain Tumors: It Is Time to Rectify the Ongoing Misconceptions. Withofs N, Kumar R, Alavi A, Hustinx R. PET Clin. 2022 Jul;17(3):327-342. doi: 10.1016/j.cpet.2022.03.004. PMID: 35717096
Role of Fluorodeoxyglucose-PET in Interventional Radiology. Zandifar A, Saucedo J, Vossough A, Alavi A, Hunt SJ. PET Clin. 2022 Jul;17(3):543-553. doi: 10.1016/j.cpet.2022.03.003. Epub 2022 May 31. PMID: 35662495
Role of Molecular Imaging with PET/MR Imaging in the Diagnosis and Management of Brain Tumors. Borja AJ, Saini J, Raynor WY, Ayubcha C, Werner TJ, Alavi A, Revheim ME, Nagaraj C. PET Clin. 2022 Jul;17(3):431-451. doi: 10.1016/j.cpet.2022.03.002. Epub 2022 May 31. PMID: 35662494
Prognostic significance of conventional and volumetric PET parameters with and without partial volume correction in the assessment of head and neck squamous cell carcinoma. Zirakchian Zadeh M, Asadollahi S, Kaghazchi F, Raynor WY, Mehdizadeh Seraj S, Werner TJ, Seierstad T, Korostoff J, Swisher-McClure S, Alavi A, Revheim ME. Nucl Med Commun. 2022 Jul 1;43(7):800-806. doi: 10.1097/MNM.0000000000001573. Epub 2022 May 13. PMID: 35552334
Stromal Notch ligands foster lymphopenia-driven functional plasticity and homeostatic proliferation of naive B cells. Gómez Atria D, Gaudette BT, Londregan J, Kelly S, Perkey E, Allman A, Srivastava B, Koch U, Radtke F, Ludewig B, Siebel CW, Ryan RJ, Robertson TF, Burkhardt JK, Pear WS, Allman D, Maillard I. J Clin Invest. 2022 Jul 1;132(13):e158885. doi: 10.1172/JCI158885. PMID: 35579963
Position-Specific Secondary Acylation Determines Detection of Lipid A by Murine TLR4 and Caspase-11. Harberts EM, Grubaugh D, Akuma DC, Shin S, Ernst RK, Brodsky IE. Infect Immun. 2022 Jul 14:e0020122. doi: 10.1128/iai.00201-22. Online ahead of print. PMID: 35862717
Lipid A Variants Activate Human TLR4 and the Noncanonical Inflammasome Differently and Require the Core Oligosaccharide for Inflammasome Activation. Alexander-Floyd J, Bass AR, Harberts EM, Grubaugh D, Buxbaum JD, Brodsky IE, Ernst RK, Shin S. Infect Immun. 2022 Jul 14:e0020822. doi: 10.1128/iai.00208-22. Online ahead of print. PMID: 35862709
Salmonella enterica Serovar Typhimurium Induces NAIP/NLRC4- and NLRP3/ASC-Independent, Caspase-4-Dependent Inflammasome Activation in Human Intestinal Epithelial Cells. Naseer N, Zhang J, Bauer R, Constant DA, Nice TJ, Brodsky IE, Rauch I, Shin S. Infect Immun. 2022 Jul 21;90(7):e0066321. doi: 10.1128/iai.00663-21. Epub 2022 Jun 9. PMID: 35678562
Simple and actionable preoperative prediction of postoperative healthcare needs of single-level lumbar fusion patients. Borja AJ, Farooqi AS, Golubovsky JL, Glauser G, Strouz K, Burkhardt JK, McClintock SD, Malhotra NR. J Neurosurg Spine. 2022 Jul 1:1-6. doi: 10.3171/2022.5.SPINE22282. Online ahead of print. PMID: 35901736
Herniation World Federation of Neurosurgical Societies Scale Improves Prediction of Outcome in Patients With Poor-Grade Aneurysmal Subarachnoid Hemorrhage. Raabe A, Beck J, Goldberg J, Z Graggen WJ, Branca M, Marbacher S, D'Alonzo D, Fandino J, Stienen MN, Neidert MC, Burkhardt JK, Regli L, Hlavica M, Seule M, Roethlisberger M, Guzman R, Zumofen DW, Maduri R, Daniel RT, El Rahal A, Corniola MV, Bijlenga P, Schaller K, Rölz R, Scheiwe C, Shah M, Heiland DH, Schnell O, Fung C. Stroke. 2022 Jul;53(7):2346-2351. doi: 10.1161/STROKEAHA.121.036699. Epub 2022 Mar 23. PMID: 35317612
The enigmatic roles of Anelloviridae and Redondoviridae in humans. Taylo LJ, Keeler EL, Bushman FD, Collman RG. Curr Opin Virol. 2022 Jul 20;55:101248. doi: 10.1016/j.coviro.2022.101248. Online ahead of print. PMID: 35870315
Partial RAG deficiency in humans induces dysregulated peripheral lymphocyte development and humoral tolerance defect with accumulation of T-bet⁺ B cells. Csomos K, Ujhazi B, Blazso P, Herrera JL, Tipton CM, Kawai T, Gordon S, Ellison M, Wu K, Stowell M, Haynes L, Cruz R, Zakota B, Nguyen J, Altrich M, Geier CB, Sharapova S, Dasso JF, Leiding JW, Smith G, Al-Herz W, de Barros Dorna M, Fadugba O, Fronkova E, Kanderova V, Svaton M, Henrickson SE, Hernandez JD, Kuijpers T, Kandilarova SM, Naumova E, Milota T, Sediva A, Moshous D, Neven B, Saco T, Sargur R, Savic S, Sleasman J, Sunkersett G, Ward BR, Komatsu M, Pittaluga S, Kumanovics A, Butte MJ, Cancro MP, Pillai S, Meffre E, Notarangelo LD, Walter JE. Nat Immunol. 2022 Jul 28. doi: 10.1038/s41590-022-01271-6. Online ahead of print. PMID: 35902638
Targeting PARP11 to avert immunosuppression and improve CAR T therapy in solid tumors. Zhang H, Yu P, Tomar VS, Chen X, Atherton MJ, Lu Z, Zhang HG, Li S, Ortiz A, Gui J, Leu NA, Yan F, Blanco A, Meyer-Ficca ML, Meyer RG, Beiting DP, Li J, Nunez-Cruz S, O'Connor RS, Johnson LR, Minn AJ, George SS, Koumenis C, Diehl JA, Milone MC, Zheng H, Fuchs SY. Nat Cancer. 2022 Jul;3(7):808-820. doi: 10.1038/s43018-022-00383-0. Epub 2022 May 30. PMID: 35637402
Epidemiology, risk factors, and outcomes of lung retransplantation: An analysis of the International Society for Heart and Lung Transplantation Thoracic Transplant Registry. Harhay MO, Cherikh WS, Toll AE, Christie JD, Stehlik J, Chambers D, Hayes D Jr, Cantu E. J Heart Lung Transplant. 2022 Jul 5:S1053-2498(22)02022-8. doi: 10.1016/j.healun.2022.06.022. Online ahead of print. PMID: 35933297
Multianalyte Prognostic Signature Including Circulating Tumor DNA and Circulating Tumor Cells in Patients With Advanced Pancreatic Adenocarcinoma. Chapin WJ, Till JE, Hwang WT, Eads JR, Karasic TB, O'Dwyer PJ, Schneider CJ, Teitelbaum UR, Romeo J, Black TA, Christensen TE, Redlinger Tabery C, Anderson A, Slade M, LaRiviere M, Yee SS, Reiss KA, O'Hara MH, Carpenter EL. JCO Precis Oncol. 2022 Jul;6:e2200060. doi: 10.1200/PO.22.00060. PMID: 35939771
Transcriptional profiling of single tumour cells from pleural effusions reveals heterogeneity of epithelial to mesenchymal transition and extra-cellular matrix marker expression . Sen M, Hausler RM, Dulmage K, Black TA, Murphy W, Pletcher CH Jr, Wang L, Chen C, Yee SS, Bornheimer SJ, Maxwell KN, Stanger BZ, Moore JS, Thompson JC, Carpenter EL. Clin Transl Med. 2022 Jul;12(7):e888. doi: 10.1002/ctm2.888. PMID: 35811459
Biomarker Testing, Treatment Uptake, and Survival Among Patients With Urothelial Cancer Receiving Gene-Targeted Therapy. Nimgaonkar V, Hubbard RA, Carpenter EL, Mamtani R. JAMA Oncol. 2022 Jul 1;8(7):1070-1072. doi: 10.1001/jamaoncol.2022.1167. PMID: 35551582
Modulation of BCL-2 in both T Cells and Tumor Cells to Enhance Chimeric Antigen Receptor T cell Immunotherapy against Cancer . Lee YG, Guruprasad P, Ghilardi G, Pajarillo R, Sauter CT, Patel R, Ballard HJ, Hong SJ, Chun I, Yang N, Amelsberg KV, Cummins KD, Svoboda J, Gill S, Chong EA, North K, Church SE, Fraietta JA, Chang WJ, Lacey SF, Lu XM, Zhang Y, Whig K, Schultz DC, Cherry S, Gerson J, Schuster SJ, Porazzi P, Ruella M. Cancer Discov. 2022 Jul 29:CD-21-1026. doi: 10.1158/2159-8290.CD-21-1026. Online ahead of print. PMID: 35904479
Altered adipose tissue macrophage populations in people with HIV on integrase inhibitor-containing ART. Vakili S, Paneru B, Guerrier CM, Miller J, Baumrin E, Forrestel A, Lynn K, Frank I, Lo Re V 3rd, Collman RG, Hill DA. AIDS. 2022 Jul 8. doi: 10.1097/QAD.0000000000003278. Online ahead of print. PMID: 35848549
Impact of atrial fibrillation recurrences during the blanking period following catheter ablation on long-term arrhythmia-free survival: a prospective study with continuous monitoring. Amankwah NA, Pothineni NVK, Guandalini G, Santangeli P, Schaller R, Supple GE, Deo R, Nazarian S, Lin D, Epstein AE, Dixit S, Callans DJ, Marchlinski FE, Frankel DS. J Interv Card Electrophysiol. 2022 Jul 7. doi: 10.1007/s10840-022-01291-0. Online ahead of print. PMID: 35794440
Decision-making Among Hepatitis C Virus-negative Transplant Candidates Offered Organs from Donors with HCV Infection. Saine ME, Schnellinger EM, Liu M, Diamond JM, Crespo MM, Prenner S, Potluri V, Bermudez C, Mentch H, Moore M, Besharatian B, Goldberg DS, Barg FK, Reese PP. Transplant Direct. 2022 Jul 19;8(8):e1341. doi: 10.1097/TXD.0000000000001341. eCollection 2022 Aug. PMID: 35923812
CXCL9 and CXCL10 plasma levels: Potential keys to unlocking CLAD risk . Shtraichman O, Diamond JM. Am J Transplant. 2022 Jul 2. doi: 10.1111/ajt.17135. Online ahead of print. PMID: 35778933
Adverse Pregnancy Outcomes in Nondiabetic Patients with an Elevated Early Pregnancy HbA1c. Bender WR, McCarthy C, Elovitz M, Parry S, Durnwald C. Am J Perinatol. 2022 Jul 5. doi: 10.1055/a-1877-8696. Online ahead of print. PMID: 35709738
Optimisation of anti-interleukin-6 therapy: Precision medicine through mathematical modelling. Rossi JF, Chiang HC, Lu ZY, Levon K, van Rhee F, Kanhai K, Fajgenbaum DC, Klein B. Front Immunol. 2022 Jul 19;13:919489. doi: 10.3389/fimmu.2022.919489. eCollection 2022. PMID: 35928820
Thrombocytopenia, anasarca, and severe inflammation. Montazeripouragha A, Campbell CM, Russell J, Medvedev N, Owen DR, Harris A, Donnellan F, McCormick I, Fajgenbaum DC, Chen LYC. Am J Hematol. 2022 Jul 6. doi: 10.1002/ajh.26651. Online ahead of print. PMID: 35794839
Siltuximab is associated with improved progression-free survival in idiopathic multicentric Castleman disease. van Rhee F, Rosenthal AL, Kanhai K, Martin RA, Nishimura KK, Hoering A, Fajgenbaum DC. Blood Adv. 2022 Jul 6:bloodadvances.2022007112. doi: 10.1182/bloodadvances.2022007112. Online ahead of print. PMID: 35793409
Idiopathic multicentric Castleman disease with arteriolar endotheliopathy and secondary haemophagocytosis. Campbell CM, Owen DR, Montazeripouragha A, McCormick I, Fajgenbaum DC, Chen LYC. Lancet Haematol. 2022 Jul;9(7):e546. doi: 10.1016/S2352-3026(22)00037-0. PMID: 35772433
The disease course of Castleman disease patients with fatal outcomes in the ACCELERATE registry. Fajgenbaum DC, Pierson SK, Kanhai K, Bagg A, Alapat D, Lim MS, Lechowicz MJ, Srkalovic G, Uldrick TS, van Rhee F; ACCELERATE Registry Team. Br J Haematol. 2022 Jul;198(2):307-316. doi: 10.1111/bjh.18214. Epub 2022 May 4. PMID: 35507638
Refractory eosinophilic esophagitis: what to do when the patient has not responded to proton pump inhibitors, steroids and diet. Strauss AL, Falk GW. Curr Opin Gastroenterol. 2022 Jul 1;38(4):395-401. doi: 10.1097/MOG.0000000000000842. PMID: 35762699
A Clinical Severity Index for Eosinophilic Esophagitis: Development, Consensus, and Future Directions. Dellon ES, Khoury P, Muir AB, Liacouras CA, Safroneeva E, Atkins D, Collins MH, Gonsalves N, Falk GW, Spergel JM, Hirano I, Chehade M, Schoepfer AM, Menard-Katcher C, Katzka DA, Bonis PA, Bredenoord AJ, Geng B, Jensen ET, Pesek RD, Feuerstadt P, Gupta SK, Lucendo AJ, Genta RM, Hiremath G, McGowan EC, Moawad FJ, Peterson KA, Rothenberg ME, Straumann A, Furuta GT, Aceves SS. Gastroenterology. 2022 Jul;163(1):59-76. doi: 10.1053/j.gastro.2022.03.025. Epub 2022 May 20. PMID: 35606197
A Clinical Severity Index for Eosinophilic Esophagitis: Development, Consensus, and Future Directions. Dellon ES, Khoury P, Muir AB, Liacouras CA, Safroneeva E, Atkins D, Collins MH, Gonsalves N, Falk GW, Spergel JM, Hirano I, Chehade M, Schoepfer AM, Menard-Katcher C, Katzka DA, Bonis PA, Bredenoord AJ, Geng B, Jensen ET, Pesek RD, Feuerstadt P, Gupta SK, Lucendo AJ, Genta RM, Hiremath G, McGowan EC, Moawad FJ, Peterson KA, Rothenberg ME, Straumann A, Furuta GT, Aceves SS. J Allergy Clin Immunol. 2022 Jul;150(1):33-47. doi: 10.1016/j.jaci.2022.03.015. Epub 2022 May 20. PMID: 35606166
Using CD69 PET Imaging to Monitor Immunotherapy-Induced Immune Activation. Edwards KJ, Chang B, Babazada H, Lohith K, Park DH, Farwell MD, Sellmyer MA. Cancer Immunol Res. 2022 Jul 21:CIR-21-0874. doi: 10.1158/2326-6066.CIR-21-0874. Online ahead of print. PMID: 35862229
The Roles of Neutrophils Linking Periodontitis and Atherosclerotic Cardiovascular Diseases . Irwandi RA, Chiesa ST, Hajishengallis G, Papayannopoulos V, Deanfield JE, D'Aiuto F. Front Immunol. 2022 Jul 7;13:915081. doi: 10.3389/fimmu.2022.915081. eCollection 2022. PMID: 35874771
Inflammatory memory and comorbidities. Hajishengallis G, Chavakis T. Clin Transl Med. 2022 Jul;12(7):e984. doi: 10.1002/ctm2.984. PMID: 35839318
Mechanisms and Therapeutic Modulation of Neutrophil-Mediated Inflammation. Hajishengallis G, Chavakis T. J Dent Res. 2022 Jul 4:220345221107602. doi: 10.1177/00220345221107602. Online ahead of print. PMID: 35786033
Impaired humoral immunity is associated with prolonged COVID-19 despite robust CD8 T cell responses . Lyudovyk O, Kim JY, Qualls D, Hwee MA, Lin YH, Boutemine SR, Elhanati Y, Solovyov A, Douglas M, Chen E, Babady NE, Ramanathan L, Vedantam P, Bandlamudi C, Gouma S, Wong P, Hensley SE, Greenbaum B, Huang AC, Vardhana SA. Cancer Cell. 2022 Jul 11;40(7):738-753.e5. doi: 10.1016/j.ccell.2022.05.013. Epub 2022 May 30. PMID: 35679859
Role of Fluorodeoxyglucose-PET in Interventional Radiology. Zandifar A, Saucedo J, Vossough A, Alavi A, Hunt SJ. PET Clin. 2022 Jul;17(3):543-553. doi: 10.1016/j.cpet.2022.03.003. Epub 2022 May 31. PMID: 35662495
Single-cell analysis highlights differences in druggable pathways underlying adaptive or fibrotic kidney regeneration . Balzer MS, Doke T, Yang YW, Aldridge DL, Hu H, Mai H, Mukhi D, Ma Z, Shrestha R, Palmer MB, Hunter CA, Susztak K. Nat Commun. 2022 Jul 11;13(1):4018. doi: 10.1038/s41467-022-31772-9. PMID: 35821371
CAR T-cell Therapy Meets Clonal Hematopoiesis. Uslu U, June CH. Blood Cancer Discov. 2022 Jul 27:OF1-OF3. doi: 10.1158/2643-3230.BCD-22-0067. Online ahead of print. PMID: 35896010
Potentiating adoptive cell therapy using synthetic IL-9 receptors. Kalbasi A, Siurala M, Su LL, Tariveranmoshabad M, Picton LK, Ravikumar P, Li P, Lin JX, Escuin-Ordinas H, Da T, Kremer SV, Sun AL, Castelli S, Agarwal S, Scholler J, Song D, Rommel PC, Radaelli E, Young RM, Leonard WJ, Ribas A, June CH, Garcia KC. Nature. 2022 Jul;607(7918):360-365. doi: 10.1038/s41586-022-04801-2. Epub 2022 Jun 8. PMID: 35676488
Multiethnic Investigation of Risk and Immune Determinants of COVID-19 Outcomes. Jun T, Mathew D, Sharma N, Nirenberg S, Huang HH, Kovatch P, Wherry EJ, Huang KL. Front Cell Infect Microbiol. 2022 Jul 22;12:933190. doi: 10.3389/fcimb.2022.933190. eCollection 2022. PMID: 35942057

June 2022

Day 4 vs. day 12 G-CSF administration following reduced intensity peripheral blood allogeneic stem cell transplant. Hatch RV, Freyer CW, Carulli A, Redline G, Babushok DV, Frey NV, Gill SI, Hexner EO, Luger SM, Martin ME, McCurdy SR, Perl AE, Porter DL, Pratz KW, Stadtmauer EA, Loren AW. J Oncol Pharm Pract. 2022 Jun;28(4):892-897. doi: 10.1177/10781552221080710. Epub 2022 Feb 22. PMID: 35191732
Surgical outcomes in survivors of childhood cancer undergoing thyroidectomy: A single-institution experience. Van Remortel BJ, Chehab L, Bauer AJ, Isaza A, Yimei L, Baumgarten HD, Franco AT, Laetsch TW, Kazahaya K, Adzick NS, Mostoufi-Moab S. Pediatr Blood Cancer. 2022 Jun;69(6):e29674. doi: 10.1002/pbc.29674. Epub 2022 Mar 26. PMID: 35338690
Interconnection of periodontal disease and comorbidities: Evidence, mechanisms, and implications. Hajishengallis G. Periodontol 2000. 2022 Jun;89(1):9-18. doi: 10.1111/prd.12430. Epub 2022 Mar 4. PMID: 35244969
Maladaptive trained immunity and clonal hematopoiesis as potential mechanistic links between periodontitis and inflammatory comorbidities. Hajishengallis G, Li X, Divaris K, Chavakis T. Periodontol 2000. 2022 Jun;89(1):215-230. doi: 10.1111/prd.12421. Epub 2022 Mar 4. PMID: 35244943
Neurotropic RNA Virus Modulation of Immune Responses within the Central Nervous System. Vazquez C, Jurado KA. Int J Mol Sci. 2022 Apr 5;23(7):4018. doi: 10.3390/ijms23074018. PMID: 35409387
Exploration of inhibitors of the bacterial LexA repressor-protease. Jaramillo AVC, Cory MB, Li A, Kohli RM, Wuest WM.Bioorg Med Chem Lett. 2022 Jun 1;65:128702. doi: 10.1016/j.bmcl.2022.128702. Epub 2022 Mar 26.PMID: 35351585
Day 4 vs. day 12 G-CSF administration following reduced intensity peripheral blood allogeneic stem cell transplant. Hatch RV, Freyer CW, Carulli A, Redline G, Babushok DV, Frey NV, Gill SI, Hexner EO, Luger SM, Martin ME, McCurdy SR, Perl AE, Porter DL, Pratz KW, Stadtmauer EA, Loren AW. J Oncol Pharm Pract. 2022 Jun;28(4):892-897. doi: 10.1177/10781552221080710. Epub 2022 Feb 22. PMID: 35191732
ACR-ACNM-ASTRO-SNMMI Practice Parameter for Lutetium-177 (Lu-177) DOTATATE Therapy . Love C, Desai NB, Abraham T, Banks KP, Bodei L, Boike T, Brown RKJ, Bushnell DL, DeBlanche LE, Dominello MM, Francis T, Grady EC, Hobbs RF, Hope TA, Kempf JS, Pryma DA, Rule W, Savir-Baruch B, Sethi I, Subramaniam RM, Xiao Y, Schechter NR. Clin Nucl Med. 2022 Jun 1;47(6):503-511. doi: 10.1097/RLU.0000000000004182. PMID: 35507433
Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer: clinical and immunologic analyses from the randomized phase 2 PRINCE trial. Padrón LJ, Maurer DM, O'Hara MH, O'Reilly EM, Wolff RA, Wainberg ZA, Ko AH, Fisher G, Rahma O, Lyman JP, Cabanski CR, Yu JX, Pfeiffer SM, Spasic M, Xu J, Gherardini PF, Karakunnel J, Mick R, Alanio C, Byrne KT, Hollmann TJ, Moore JS, Jones DD, Tognetti M, Chen RO, Yang X, Salvador L, Wherry EJ, Dugan U, O'Donnell-Tormey J, Butterfield LH, Hubbard-Lucey VM, Ibrahim R, Fairchild J, Bucktrout S, LaVallee TM, Vonderheide RH. Nat Med. 2022 Jun 3. doi: 10.1038/s41591-022-01829-9. Online ahead of print. PMID: 35662283
The X in seX-biased immunity and autoimmune rheumatic disease. Jiwrajka N, Anguera MC. J Exp Med. 2022 Jun 6;219(6):e20211487. doi: 10.1084/jem.20211487. Epub 2022 May 5. PMID: 35510951
Markers of fungal translocation are elevated during post-acute sequelae of SARS-CoV-2 and induce NF-κB signaling. Giron LB, Peluso MJ, Ding J, Kenny G, Zilberstein NF, Koshy J, Hong KY, Rasmussen H, Miller GE, Bishehsari F, Balk RA, Moy JN, Hoh R, Lu S, Goldman AR, Tang HY, Yee BC, Chenna A, Winslow JW, Petropoulos CJ, Kelly JD, Wasse H, Martin JN, Liu Q, Keshavarzian A, Landay A, Deeks SG, Henrich TJ, Abdel-Mohsen M. JCI Insight. 2022 Jun 21:e160989. doi: 10.1172/jci.insight.160989. Online ahead of print. PMID: 35727635
Application of ¹⁸F-NaF-PET/CT in assessing age-related changes in the cervical spine. Park PSU, Raynor WY, Khurana N, Sun Y, Werner TJ, Høilund-Carlsen PF, Alavi A, Revheim ME. Quant Imaging Med Surg. 2022 Jun;12(6):3314-3324. doi: 10.21037/qims-21-1174. PMID: 35655822
Spatiotemporal Patterns of Substance P-Bound MRGPRX2 Reveal a Novel Connection Between Macropinosome Resolution and Secretory Granule Regeneration in Mast Cells. Lazki-Hagenbach P, Kleeblatt E, Ali H, Sagi-Eisenberg R. Front Immunol. 2022 Jun 28;13:892239. doi: 10.3389/fimmu.2022.892239. eCollection 2022. PMID: 35837385
Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses. Alameh MG, Tombácz I, Bettini E, Lederer K, Sittplangkoon C, Wilmore JR, Gaudette BT, Soliman OY, Pine M, Hicks P, Manzoni TB, Knox JJ, Johnson JL, Laczkó D, Muramatsu H, Davis B, Meng W, Rosenfeld AM, Strohmeier S, Lin PJC, Mui BL, Tam YK, Karikó K, Jacquet A, Krammer F, Bates P, Cancro MP, Weissman D, Luning Prak ET, Allman D, Locci M, Pardi N. Immunity. 2022 Jun 14;55(6):1136-1138. doi: 10.1016/j.immuni.2022.05.007 .PMID: 35704995
Editorial: Role of Inflammation in Neurodegenerative Diseases. Koronyo-Hamaoui M, Gaire BP, Frautschy SA, Alvarez JI. Front Immunol. 2022 Jun 21;13:958487. doi: 10.3389/fimmu.2022.958487. eCollection 2022. PMID: 35799792
Understanding the Pathogenesis of Lateral Supratentorial Neurenteric Cysts in Close Proximity to Other Vascular Pathologies: A Case Report and Review of Embryology. Salem MM, Mccloskey K, Romeo D, Gubbiotti M, Su YS, DePace DM, Jankowitz BT, Burkhardt JK. Cureus. 2022 Jun 2;14(6):e25608. doi: 10.7759/cureus.25608. eCollection 2022 Jun. PMID: 35784991
Bailout Strategies for Abrupt Change in Woven Endobridge 17 Device Orientation After Detachments: Technical Note of 2 Anterior Communicating Artery Aneurysm Cases. Salem MM, Ali A, Riina HA, Burkhardt JK. World Neurosurg. 2022 Jun;162:68-72. doi: 10.1016/j.wneu.2022.03.081. Epub 2022 Mar 22. PMID: 35338022
Evaluating the state of the science for adeno-associated virus integration: An integrated perspective. Sabatino DE, Bushman FD, Chandler RJ, Crystal RG, Davidson BL, Dolmetsch R, Eggan KC, Gao G, Gil-Farina I, Kay MA, McCarty DM, Montini E, Ndu A, Yuan J; American Society of Gene and Cell Therapy (ASGCT) Working Group on AAV Integration. Mol Ther. 2022 Jun 10:S1525-0016(22)00364-1. doi: 10.1016/j.ymthe.2022.06.004. Online ahead of print. PMID: 35690906
Comprehensive Serum Proteome Profiling of Cytokine Release Syndrome and Immune Effector Cell Associated Neurotoxicity Syndrome in B-Cell ALL Patients Receiving CART19. Diorio C, Shraim R, Myers R, Behrens EM, Canna S, Bassiri H, Aplenc R, Burudpakdee C, Chen F, DiNofia AM, Gill S, Gonzalez V, Lambert MP, Barz Leahy A, Levine BL, Lindell RB, Maude SL, Melenhorst JJ, Newman H, Perazzelli J, Seif AE, Lacey SF, June CH, Barrett DM, Grupp SA, Teachey DT. Clin Cancer Res. 2022 Jun 15:clincanres.CCR-22-0822-E.2022-3-15 10:15:45.960. doi: 10.1158/1078-0432.CCR-22-0822. Online ahead of print. PMID: 35705524
Ex-vivo lung perfusion therapies: do they add value to organ donation? Lyengar A, Schiazza A, Cantu E 3rd. Curr Opin Organ Transplant. 2022 Jun 1;27(3):204-210. doi: 10.1097/MOT.0000000000000961. PMID: 35649110
Impact of secondary TCR engagement on the heterogeneity of pathogen-specific CD8+ T cell response during acute and chronic toxoplasmosis. Shallberg LA, Phan AT, Christian DA, Perry JA, Haskins BE, Beiting DP, Harris TH, Koshy AA, Hunter CA. PLoS Pathog. 2022 Jun 21;18(6):e1010296. doi: 10.1371/journal.ppat.1010296. eCollection 2022 Jun. PMID: 35727849
Histone methyltransferase DOT1L is essential for self-renewal of germline stem cells. Lin H, Cheng K, Kubota H, Lan Y, Riedel SS, Kakiuchi K, Sasaki K, Bernt KM, Bartolomei MS, Luo M, Wang PJ. Genes Dev. 2022 Jun 1;36(11-12):752-763. doi: 10.1101/gad.349550.122. Epub 2022 Jun 23. PMID: 35738678
Publisher Correction: Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells. Qin K, Huang P, Feng R, Keller CA, Peslak SA, Khandros E, Saari MS, Lan X, Mayuranathan T, Doerfler PA, Abdulmalik O, Giardine B, Chou ST, Shi J, Hardison RC, Weiss MJ, Blobel GA. Nat Genet. 2022 Jun;54(6):906. doi: 10.1038/s41588-022-01112-0. PMID: 35650318
Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells . Qin K, Huang P, Feng R, Keller CA, Peslak SA, Khandros E, Saari MS, Lan X, Mayuranathan T, Doerfler PA, Abdulmalik O, Giardine B, Chou ST, Shi J, Hardison RC, Weiss MJ, Blobel GA. Nat Genet. 2022 Jun;54(6):874-884. doi: 10.1038/s41588-022-01076-1. Epub 2022 May 26. PMID: 35618846
Development of a robust radiomic biomarker of progression-free survival in advanced non-small cell lung cancer patients treated with first-line immunotherapy . Singh A, Horng H, Roshkovan L, Weeks JK, Hershman M, Noël P, Luna JM, Cohen EA, Pantalone L, Shinohara RT, Bauml JM, Thompson JC, Aggarwal C, Carpenter EL, Katz SI, Kontos D. Sci Rep. 2022 Jun 15;12(1):9993. doi: 10.1038/s41598-022-14160-7. PMID: 35705618
ADP and Thromboxane Inhibitors Both Reduce Global Contraction of Clot Length, While Thromboxane Inhibition Attenuates Internal Aggregate Contraction. Trigani KT, DeCortin ME, Diamond SL. TH Open. 2022 Jun 13;6(2):e135-e143. doi: 10.1055/a-1832-9293. eCollection 2022 Apr. PMID: 35707619
Tissue mechanics coevolves with fibrillar matrisomes in healthy and fibrotic tissues. Dooling LJ, Saini K, Anlaş AA, Discher DE. Matrix Biol. 2022 Jun 25:S0945-053X(22)00086-5. doi: 10.1016/j.matbio.2022.06.006. Online ahead of print. PMID: 35764212
Nuclear mechanoprotection: From tissue atlases as blueprints to distinctive regulation of nuclear lamins. Wang M, Ivanovska I, Vashisth M, Discher DE. APL Bioeng. 2022 Jun 15;6(2):021504. doi: 10.1063/5.0080392. eCollection 2022 Jun. PMID: 35719698
Maternal immune response and placental antibody transfer after COVID-19 vaccination across trimester and platforms. Atyeo CG, Shook LL, Brigida S, De Guzman RM, Demidkin S, Muir C, Akinwunmi B, Baez AM, Sheehan ML, McSweeney E, Burns MD, Nayak R, Kumar MK, Patel CD, Fialkowski A, Cvrk D, Goldfarb IT, Yonker LM, Fasano A, Balazs AB, Elovitz MA, Gray KJ, Alter G, Edlow AG. Nat Commun. 2022 Jun 28;13(1):3571. doi: 10.1038/s41467-022-31169-8. PMID: 35764643
Prospective Evaluation of Cardiovascular Risk 10 Years After a Hypertensive Disorder of Pregnancy. Levine LD, Ky B, Chirinos JA, Koshinksi J, Arany Z, Riis V, Elovitz MA, Koelper N, Lewey J. J Am Coll Cardiol. 2022 Jun 21;79(24):2401-2411. doi: 10.1016/j.jacc.2022.03.383. PMID: 35710191
Lipid metabolism in the cervicovaginal space during pregnancy. Gerson KD, Elovitz MA, Burris HH. Am J Obstet Gynecol. 2022 Jun 6:S0002-9378(22)00445-8. doi: 10.1016/j.ajog.2022.05.067. Online ahead of print. PMID: 35679894
Anti-type I interferon antibodies as a cause of severe COVID-19. Fajgenbaum DC, Hayday AC, Rogers AJ, Towers GJ, Wack A, Zanoni I. Fac Rev. 2022 Jun 10;11:15. doi: 10.12703/r-01-0000010. eCollection 2022. PMID: 35812362
A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression. Verginadis II, Avgousti H, Monslow J, Skoufos G, Chinga F, Kim K, Leli NM, Karagounis IV, Bell BI, Velalopoulou A, Salinas CS, Wu VS, Li Y, Ye J, Scott DA, Osterman AL, Sengupta A, Weljie A, Huang M, Zhang D, Fan Y, Radaelli E, Tobias JW, Rambow F, Karras P, Marine JC, Xu X, Hatzigeorgiou AG, Ryeom S, Diehl JA, Fuchs SY, Puré E, Koumenis C. Nat Cell Biol. 2022 Jun;24(6):940-953. doi: 10.1038/s41556-022-00918-8. Epub 2022 Jun 2. PMID: 35654839
A phase I trial of cyclosporine for hospitalized patients with COVID-19. Blumberg EA, Noll JH, Tebas P, Fraietta JA, Frank I, Marshall A, Chew A, Veloso EA, Carulli A, Rogal W, Gaymon AL, Schmidt AH, Barnette T, Jurek R, Martins R, Hudson BM, Chavda K, Bailey CM, Church SE, Noorchashm H, Hwang WT, June CH, Hexner EO. JCI Insight. 2022 Jun 8;7(11):e155682. doi: 10.1172/jci.insight.155682. PMID: 35536669
Association of S100A8/A9 with Lipid-Rich Necrotic Core and Treatment with Biologic Therapy in Patients with Psoriasis: Results from an Observational Cohort Study. Berg AR, Hong CG, Svirydava M, Li H, Parel PM, Florida E, O'Hagan R, Pantoja CJ, Lateef SS, Anzenberg P, Harrington CL, Ward G, Zhou W, Sorokin AV, Chen MY, Teague HL, Buckler AJ, Playford MP, Gelfand JM, Mehta NN. J Invest Dermatol. 2022 Jun 21:S0022-202X(22)01527-5. doi: 10.1016/j.jid.2022.05.1085. Online ahead of print. PMID: 35750149
Is It Prime Time for Statin Therapy in Psoriasis? Mehta NN, Gelfand JM. J Invest Dermatol. 2022 Jun;142(6):1519-1522. doi: 10.1016/j.jid.2022.02.020. PMID: 35598898
Regional specification of oral mucosal immunity. Williams DW, Hajishengallis G, Moutsopoulos NM. Sci Immunol. 2022 Jun 24;7(72):eabp8632. doi: 10.1126/sciimmunol.abp8632. Epub 2022 Jun 17. PMID: 35714199
C3-targeted host-modulation approaches to oral inflammatory conditions . Kajikawa T, Mastellos DC, Hasturk H, Kotsakis GA, Yancopoulou D, Lambris JD, Hajishengallis G. Semin Immunol. 2022 Jun 9:101608. doi: 10.1016/j.smim.2022.101608. Online ahead of print. PMID: 35691883
Nuclear Coregulatory Complexes in Tregs as Targets to Promote Anticancer Immune Responses . Christensen LM, Hancock WW. Front Immunol. 2022 Jun 20;13:909816. doi: 10.3389/fimmu.2022.909816. eCollection 2022. PMID: 35795673
The Selective Estrogen Receptor Modulator, Raloxifene, Is Protective Against Renal Ischemia-Reperfusion Injury. Hernandez P, O'Brien C, Concors SJ, Wang Z, Ge G, Hancock WW, Levine MH. Transplantation. 2022 Jun 3. doi: 10.1097/TP.0000000000004194. Online ahead of print. PMID: 35655356
Assessment of SARS-CoV-2 serostatus and hypertensive disorders of pregnancy. Triebwasser JE, Dhudasia MB, Mukhopadhyay S, Flannery DD, Gouma S, Hensley SE, Puopolo KM. Am J Obstet Gynecol. 2022 Jun 16:S0002-9378(22)00458-6. doi: 10.1016/j.ajog.2022.06.012. Online ahead of print. PMID: 35718110
Neighborhood Characteristics and Racial Disparities in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Seropositivity in Pregnancy. Burris HH, Mullin AM, Dhudasia MB, Flannery DD, Mukhopadhyay S, Pfeifer MR, Woodford EC, Briker SM, Triebwasser JE, Morris JS, Montoya-Williams D, Gouma S, Hensley SE, Puopolo KM. Obstet Gynecol. 2022 Jun 1;139(6):1018-1026. doi: 10.1097/AOG.0000000000004791. Epub 2022 May 2. PMID: 35675599
The 2009 Pandemic H1N1 Hemagglutinin Stalk Remained Antigenically Stable after Circulating in Humans for a Decade. Christensen SR, Martin ET, Petrie JG, Monto AS, Hensley SE. J Virol. 2022 Jun 8;96(11):e0220021. doi: 10.1128/jvi.02200-21. Epub 2022 May 19. PMID: 35588275
Inflammatory adipose activates a nutritional immunity pathway leading to retinal dysfunction . Sterling JK, Baumann B, Foshe S, Voigt A, Guttha S, Alnemri A, McCright SJ, Li M, Zauhar RJ, Montezuma SR, Kapphahn RJ, Chavali VRM, Hill DA, Ferrington DA, Stambolian D, Mullins RF, Merrick D, Dunaief JL. Cell Rep. 2022 Jun 14;39(11):110942. doi: 10.1016/j.celrep.2022.110942. PMID: 35705048
A cellular trafficking signal in the SIV envelope protein cytoplasmic domain is strongly selected for in pathogenic infection. Lawrence SP, Elser SE, Torben W, Blair RV, Pahar B, Aye PP, Schiro F, Szeltner D, Doyle-Meyers LA, Haggarty BS, Jordan APO, Romano J, Leslie GJ, Alvarez X, O'Connor DH, Wiseman RW, Fennessey CM, Li Y, Piatak M Jr, Lifson JD, LaBranche CC, Lackner AA, Keele BF, Maness NJ, Marsh M, Hoxie JA. PLoS Pathog. 2022 Jun 17;18(6):e1010507. doi: 10.1371/journal.ppat.1010507. eCollection 2022 Jun. PMID: 35714165
Broad coverage of neutralization-resistant SIV strains by second-generation SIV-specific antibodies targeting the region involved in binding CD4. Welles HC, King HAD, Nettey L, Cavett N, Gorman J, Zhou T, Tsybovsky Y, Du R, Song K, Nguyen R, Ambrozak D, Ransier A, Schramm CA, Doria-Rose NA, Swanstrom AE, Hoxie JA, LaBranche C, Montefiori DC, Douek DC, Kwong PD, Mascola JR, Roederer M, Mason RD. PLoS Pathog. 2022 Jun 16;18(6):e1010574. doi: 10.1371/journal.ppat.1010574. eCollection 2022 Jun. PMID: 35709309
Preclinical platforms to study therapeutic efficacy of human γδ T cells. Ou L, Wang H, Huang H, Zhou Z, Lin Q, Guo Y, Mitchell T, Huang AC, Karakousis G, Schuchter L, Amaravadi R, Guo W, Salvino J, Herlyn M, Xu X. Clin Transl Med. 2022 Jun;12(6):e814. doi: 10.1002/ctm2.814. PMID: 35731974
Single-cell analysis identifies the interaction of altered renal tubules with basophils orchestrating kidney fibrosis . Doke T, Abedini A, Aldridge DL, Yang YW, Park J, Hernandez CM, Balzer MS, Shrestra R, Coppock G, Rico JMI, Han SY, Kim J, Xin S, Piliponsky AM, Angelozzi M, Lefebvre V, Siracusa MC, Hunter CA, Susztak K. Nat Immunol. 2022 Jun;23(6):947-959. doi: 10.1038/s41590-022-01200-7. Epub 2022 May 12. PMID: 35552540
Use of JYNNEOS (Smallpox and Monkeypox Vaccine, Live, Nonreplicating) for Preexposure Vaccination of Persons at Risk for Occupational Exposure to Orthopoxviruses: Recommendations of the Advisory Committee on Immunization Practices - United States, 2022. Rao AK, Petersen BW, Whitehill F, Razeq JH, Isaacs SN, Merchlinsky MJ, Campos-Outcalt D, Morgan RL, Damon I, Sánchez PJ, Bell BP. MMWR Morb Mortal Wkly Rep. 2022 Jun 3;71(22):734-742. doi: 10.15585/mmwr.mm7122e1. PMID: 35653347
Single-cell antigen-specific landscape of CAR T infusion product identifies determinants of CD19-positive relapse in patients with ALL . Bai Z, Woodhouse S, Zhao Z, Arya R, Govek K, Kim D, Lundh S, Baysoy A, Sun H, Deng Y, Xiao Y, Barrett DM, Myers RM, Grupp SA, June CH, Fan R, Camara PG, Melenhorst JJ. Sci Adv. 2022 Jun 10;8(23):eabj2820. doi: 10.1126/sciadv.abj2820. Epub 2022 Jun 8. PMID: 35675405

May 2022

Autoreactive CD8⁺ T cells are restrained by an exhaustion-like program that is maintained by LAG3 . Grebinoski S, Zhang Q, Cillo AR, Manne S, Xiao H, Brunazzi EA, Tabib T, Cardello C, Lian CG, Murphy GF, Lafyatis R, Wherry EJ, Das J, Workman CJ, Vignali DAA. Nat Immunol. 2022 May 26. doi: 10.1038/s41590-022-01210-5. Online ahead of print. PMID: 35618829
Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine. Goel RR, Painter MM, Lundgreen KA, Apostolidis SA, Baxter AE, Giles JR, Mathew D, Pattekar A, Reynaldi A, Khoury DS, Gouma S, Hicks P, Dysinger S, Hicks A, Sharma H, Herring S, Korte S, Kc W, Oldridge DA, Erickson RI, Weirick ME, McAllister CM, Awofolaju M, Tanenbaum N, Dougherty J, Long S, D'Andrea K, Hamilton JT, McLaughlin M, Williams JC, Adamski S, Kuthuru O, Drapeau EM, Davenport MP, Hensley SE, Bates P, Greenplate AR, Wherry EJ. Cell. 2022 May 26;185(11):1875-1887.e8. doi: 10.1016/j.cell.2022.04.009. Epub 2022 Apr 8. PMID: 35523182
Late renal allograft torsion in a pediatric transplant recipient. Hsiao WC, Abt P, Amaral S, Levine M, LaRosa C. Pediatr Transplant. 2022 May;26(3):e14210. doi: 10.1111/petr.14210. Epub 2021 Dec 15. PMID: 34907635
Mas-Related G Protein-Coupled Receptor-X2 and Its Role in Non-immunoglobulin E-Mediated Drug Hypersensitivity. Chompunud Na Ayudhya C, Ali H. Immunol Allergy Clin North Am. 2022 May;42(2):269-284. doi: 10.1016/j.iac.2021.12.003. Epub 2022 Mar 31. PMID: 35469618
Metformin for Treatment of Cytopenias in Children and Young Adults with Fanconi Anemia. Pollard J, Furutani E, Liu S, Esrick EB, Cohen LE, Bledsoe JR, Liu CW, Lu K, Ramírez MJ, Surrallés J, Malsch MM, Kuniholm A, Galvin A, Armant M, Kim AS, Ballotti K, Moreau LA, Zhou Y, Babushok DV, Boulad F, Carroll C, Hartung H, Hont A, Nakano TA, Olson TS, Sze SK, Thompson AA, Wlodarski MW, Gu X, Libermann TA, D'Andrea AD, Grompe MCP, Weller E, Shimamura A. Blood Adv. 2022 May 2:bloodadvances.2021006490. doi: 10.1182/bloodadvances.2021006490. Online ahead of print. PMID: 35500223
IL-1 receptor antagonist, MIS-C, and the peculiar autoimmunity of SARS-CoV-2. Bassiri H, Canna SW. Lancet Rheumatol. 2022 May;4(5):e305-e307. doi: 10.1016/S2665-9913(22)00090-X. Epub 2022 Mar 29. PMID: 35368385
Improvement in eosinophilic esophagitis when using dupilumab for other indications or compassionate use. Spergel BL, Ruffner MA, Godwin BC, Liacouras CA, Cianferoni A, Gober L, Hill DA, Brown-Whitehorn TF, Chaiboonma K, Aceves SA, Muir AM, Spergel JM. Ann Allergy Asthma Immunol. 2022 May;128(5):589-593. doi: 10.1016/j.anai.2022.01.019. Epub 2022 Jan 25. PMID: 35085819
The MHC-characterized Miniature Swine: Lessons Learned From a 40-Year Experience in Transplantation. Matar AJ, Sachs DH, Duran-Struuck R. Transplantation. 2022 May 1;106(5):928-937. doi: 10.1097/TP.0000000000003977. Epub 2021 Oct 29. PMID: 34720103
Evaluating Eosinophilic Colitis as a Unique Disease Using Colonic Molecular Profiles: A Multi-Site Study. Shoda T, Collins MH, Rochman M, Wen T, Caldwell JM, Mack LE, Osswald GA, Besse JA, Haberman Y, Aceves SS, Arva NC, Capocelli KE, Chehade M, Davis CM, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Khoury P, Klion A, Menard-Katcher C, Leung J, Mukkada VA, Putnam PE, Spergel JM, Wechsler JB, Yang GY, Furuta GT, Denson LA, Rothenberg ME; Consortium of Eosinophilic Gastrointestinal Diseases Researchers (CEGIR). Gastroenterology. 2022 May;162(6):1635-1649. doi: 10.1053/j.gastro.2022.01.022. Epub 2022 Jan 25. PMID: 35085569
CD8-Targeted PET Imaging of Tumor-Infiltrating T Cells in Patients with Cancer: A Phase I First-in-Humans Study of ⁸⁹Zr-Df-IAB22M2C, a Radiolabeled Anti-CD8 Minibody. Farwell MD, Gamache RF, Babazada H, Hellmann MD, Harding JJ, Korn R, Mascioni A, Le W, Wilson I, Gordon MS, Wu AM, Ulaner GA, Wolchok JD, Postow MA, Pandit-Taskar N. J Nucl Med. 2022 May;63(5):720-726. doi: 10.2967/jnumed.121.262485. Epub 2021 Aug 19. PMID: 34413145
Analysis of Specialist and Patient Perspectives on Strategies to Improve Cardiovascular Disease Prevention Among Persons With Psoriatic Disease. Barbieri JS, Beidas RS, Gondo GC, Fishman J, Williams NJ, Armstrong AW, Ogdie AR, Mehta N, Gelfand JM. JAMA Dermatol. 2022 Mar 1;158(3):252-259. doi: 10.1001/jamadermatol.2021.4467. PMID: 35044419
Nontraumatic Chylothorax and Chylopericardium: Diagnosis and Treatment Using an Algorithmic Approach Based on Novel Lymphatic Imaging. Gurevich A, Hur S, Singhal S, DiBardino D, Haas AR, Hansen-Flaschen JH, Nadolski G, Itkin M. Ann Am Thorac Soc. 2022 May;19(5):756-762. doi: 10.1513/AnnalsATS.202103-262OC. PMID: 34797746
Global Health and Interventional Radiology: Supporting Trainee Engagement and Diversity for Future Development. Matsumoto MM, Dixon R, Anton K, Hunt SJ, Kesselman A. J Vasc Interv Radiol. 2022 May;33(5):604-606.e2. doi: 10.1016/j.jvir.2022.01.005. Epub 2022 Jan 29. PMID: 35092852
Macrophage-produced VEGFC is induced by efferocytosis to ameliorate cardiac injury and inflammation. Glinton KE, Ma W, Lantz C, Grigoryeva LS, DeBerge M, Liu X, Febbraio M, Kahn M, Oliver G, Thorp EB. J Clin Invest. 2022 May 2;132(9):e140685. doi: 10.1172/JCI140685. PMID: 35271504
Gene therapy for Fibrodysplasia Ossificans Progressiva (FOP): feasibility and obstacles. Eekhoff EMW, de Ruiter RD, Smilde BJ, Schoenmaker T, Vries TJ, Netelenbos C, Hsiao EC, Scott C, Haga N, Grunwald Z, De Cunto CL, Di Rocco M, Delai P, Diecidue R, Madhuri V, Cho TJ, Morhart R, Friedman C, Zasloff M, Pals G, Shim JH, Gao G, Kaplan F, Pignolo RJ, Micha D. Hum Gene Ther. 2022 May 2. doi: 10.1089/hum.2022.023. Online ahead of print. PMID: 35502479
Thrombin cleavage of osteopontin initiates osteopontin's tumor-promoting activity. Peraramelli S, Zhou Q, Zhou Q, Wanko B, Zhao L, Nishimura T, Leung TH, Mizuno S, Ito M, Myles T, Stulnig TM, Morser J, Leung LLK .J Thromb Haemost. 2022 May;20(5):1256-1270. doi: 10.1111/jth.15663. Epub 2022 Feb 16. PMID: 35108449
β-Hydroxybutyrate suppresses colorectal cancer . Dmitrieva-Posocco O, Wong AC, Lundgren P, Golos AM, Descamps HC, Dohnalová L, Cramer Z, Tian Y, Yueh B, Eskiocak O, Egervari G, Lan Y, Liu J, Fan J, Kim J, Madhu B, Schneider KM, Khoziainova S, Andreeva N, Wang Q, Li N, Furth EE, Bailis W, Kelsen JR, Hamilton KE, Kaestner KH, Berger SL, Epstein JA, Jain R, Li M, Beyaz S, Lengner CJ, Katona BW, Grivennikov SI, Thaiss CA, Levy M. Nature. 2022 May;605(7908):160-165. doi: 10.1038/s41586-022-04649-6. Epub 2022 Apr 27. PMID: 35477756
Real-world effectiveness of CPX-351 vs venetoclax and azacitidine in acute myeloid leukemia. Matthews AH, Perl AE, Luger SM, Loren AW, Gill SI, Porter DL, Babushok DV, Maillard I, Carroll MP, Frey NV, Hexner E, Martin ME, McCurdy SR, Stadtmauer EA, Paralkar VR, Jordan Bruno X, Hwang WT, Margolis D, Pratz KW. Blood Adv. 2022 May 4:bloodadvances.2022007265. doi: 10.1182/bloodadvances.2022007265. Online ahead of print. PMID: 35507945
Cardiovascular Risk Factors and Target Organ Damage in Adolescents: The SHIP AHOY Study. Price JJ, Urbina EM, Carlin K, Becker R, Daniels SR, Falkner BE, Ferguson M, Hanevold C, Hooper SR, Ingelfinger JR, Lande MB, Martin LJ, Meyers K, Mitsnefes M, Rosner B, Samuels J, Flynn JT. Pediatrics. 2022 May 3:e2021054201. doi: 10.1542/peds.2021-054201. Online ahead of print. PMID: 35502610
Use of hyphenated analytical techniques to identify the bioactive constituents of Gunnera perpensa L., a South African medicinal plant, which potently inhibit SARS-CoV-2 spike glycoprotein-host ACE2 binding. Invernizzi L, Moyo P, Cassel J, Isaacs FJ, Salvino JM, Montaner LJ, Tietjen I, Maharaj V. Anal Bioanal Chem. 2022 May;414(13):3971-3985. doi: 10.1007/s00216-022-04041-3. Epub 2022 Apr 14. PMID: 35419694
EBF1 nuclear repositioning instructs chromatin refolding to promote therapy resistance in T leukemic cells. Zhou Y, Petrovic J, Zhao J, Zhang W, Bigdeli A, Zhang Z, Berger SL, Pear WS, Faryabi RB. Mol Cell. 2022 Mar 3;82(5):1003-1020.e15. doi: 10.1016/j.molcel.2022.01.015. Epub 2022 Feb 18. PMID: 35182476
Immunologic and Infectious Concerns in Uterus Transplantation. Porrett PM, Nellore A. Clin Obstet Gynecol. 2022 Mar 1;65(1):37-43. doi: 10.1097/GRF.0000000000000686. PMID: 35045023
Real-world effectiveness of CPX-351 vs venetoclax and azacitidine in acute myeloid leukemia. Matthews AH, Perl AE, Luger SM, Loren AW, Gill SI, Porter DL, Babushok DV, Maillard I, Carroll MP, Frey NV, Hexner E, Martin ME, McCurdy SR, Stadtmauer EA, Paralkar VR, Jordan Bruno X, Hwang WT, Margolis D, Pratz KW. Blood Adv. 2022 May 4:bloodadvances.2022007265. doi: 10.1182/bloodadvances.2022007265. Online ahead of print. PMID: 35507945
Improvement in eosinophilic esophagitis when using dupilumab for other indications or compassionate use. Spergel BL, Ruffner MA, Godwin BC, Liacouras CA, Cianferoni A, Gober L, Hill DA, Brown-Whitehorn TF, Chaiboonma K, Aceves SA, Muir AM, Spergel JM. Ann Allergy Asthma Immunol. 2022 May;128(5):589-593. doi: 10.1016/j.anai.2022.01.019. Epub 2022 Jan 25. PMID: 35085819
Radiation therapy for head and neck cancer leads to gingival recession associated with dental caries. Lalla RV, Treister NS, Sollecito TP, Schmidt BL, Patton LL, Helgeson ES, Lin A, Rybczyk C, Dowsett R, Hegde U, Boyd TS, Duplinsky TG, Brennan MT. Oral Surg Oral Med Oral Pathol Oral Radiol. 2022 May;133(5):539-546. doi: 10.1016/j.oooo.2022.01.016. Epub 2022 Jan 31. PMID: 35304084
Sex-based disparities in outcome in pediatric acute lymphoblastic leukemia: a Children's Oncology Group report. Gupta S, Teachey DT, Chen Z, Rabin KR, Dunsmore KP, Larsen EC, Maloney KW, Mattano LA Jr, Winter SS, Carroll AJ, Heerema NA, Borowitz MJ, Wood BL, Carroll WL, Raetz EA, Winick NJ, Loh ML, Hunger SP, Devidas M. Cancer. 2022 May 1;128(9):1863-1870. doi: 10.1002/cncr.34150. Epub 2022 Feb 24. PMID: 35201611
Topologically associating domains are disrupted by evolutionary genome rearrangements forming species-specific enhancer connections in mice and humans. Gilbertson SE, Walter HC, Gardner K, Wren SN, Vahedi G, Weinmann AS. Cell Rep. 2022 May 3;39(5):110769. doi: 10.1016/j.celrep.2022.110769. PMID: 35508135
CMV infection and management among pediatric solid organ transplant recipients. Downes KJ, Sharova A, Boge CLK, Vader D, Mitrou M, Hayes M, Galetaki DM, Gianchetti L, Vella LA, Li Y. Pediatr Transplant. 2022 May;26(3):e14220. doi: 10.1111/petr.14220. Epub 2022 Jan 6. PMID: 34994041
Prime-boost vaccination regimens with INO-4800 and INO-4802 augment and broaden immune responses against SARS-CoV-2 in nonhuman primates. Walters JN, Schouest B, Patel A, Reuschel EL, Schultheis K, Parzych E, Maricic I, Gary EN, Purwar M, Andrade VM, Doan A, Elwood D, Eblimit Z, Nguyen B, Frase D, Zaidi FI, Kulkarni A, Generotti A, Joseph Kim J, Humeau LM, Ramos SJ, Smith TRF, Weiner DB, Broderick KE. Vaccine. 2022 May 9;40(21):2960-2969. doi: 10.1016/j.vaccine.2022.03.060. Epub 2022 Apr 4. PMID: 35428500
Immunological features in de novo and recurrent glioblastoma associate with survival outcomes. Alanio C, Binder ZA, Chang RB, Nasrallah MP, Delman D, Li JH, Tang OY, Zhang LY, Zhang JV, Wherry EJ, O'Rourke DM, Beatty GL. Cancer Immunol Res. 2022 May 4:canimm.CIR-21-1050-E.2021. doi: 10.1158/2326-6066.CIR-21-1050. Online ahead of print. PMID: 35507919
NHLBI Report: Impact of Sex and Gender on Autoimmune Lung Disease, Opportunities for Future Research. Volkmann ER, Siegfried J, Lahm T, Ventetuolo CE, Mathai SC, Steen V, Herzog EL, Shansky R, Anguera MC, Danoff SK, Giles JT, Lee YC, Drake W, Maier LA, Lachowicz-Scroggins M, Park H, Banerjee K, Fessel J, Reineck L, Vuga L, Crouser E, Feghali-Bostwick C. Am J Respir Crit Care Med. 2022 May 13. doi: 10.1164/rccm.202112-2746PP. Online ahead of print. PMID: 35549658
Editorial: Immunoglobulin Glycosylation Analysis: State-of-the-Art Methods and Applications in Immunology. Trbojević-Akmačić I, Abdel-Mohsen M, Falck D, Rapp E. Front Immunol. 2022 May 20;13:923393. doi: 10.3389/fimmu.2022.923393. eCollection 2022. PMID: 35669775
Trends and Outcomes of Primary, Rescue, and Adjunct Middle Meningeal Artery Embolization for Chronic Subdural Hematomas. Nia AM, Srinivasan VM, Siddiq F, Thomas A, Burkhardt JK, Lall RR, Kan P. World Neurosurg. 2022 May 10:S1878-8750(22)00598-8. doi: 10.1016/j.wneu.2022.05.011. Online ahead of print. PMID: 35552029
The pediatric virome in health and disease. Liang G, Gao H, Bushman FD. Cell Host Microbe. 2022 May 11;30(5):639-649. doi: 10.1016/j.chom.2022.04.006. PMID: 35550667
A genetic screen identifies a protective type III interferon response to Cryptosporidium that requires TLR3 dependent recognition. Gibson AR, Sateriale A, Dumaine JE, Engiles JB, Pardy RD, Gullicksrud JA, O'Dea KM, Doench JG, Beiting DP, Hunter CA, Striepen B. PLoS Pathog. 2022 May 18;18(5):e1010003. doi: 10.1371/journal.ppat.1010003. eCollection 2022 May. PMID: 35584177
Reestablishment of spermatogenesis after more than 20 years of cryopreservation of rat spermatogonial stem cells reveals an important impact in differentiation capacity. Whelan EC, Yang F, Avarbock MR, Sullivan MC, Beiting DP, Brinster RL. PLoS Biol. 2022 May 10;20(5):e3001618. doi: 10.1371/journal.pbio.3001618. eCollection 2022 May. PMID: 35536782
Identification and characterization of RBM12 as a novel regulator of fetal hemoglobin expression. Wakabayashi A, Kihiu M, Sharma M, Thrasher AJ, Saari MS, Quesnel-Vallieres M, Abdulmalik O, Peslak SA, Khandros E, Keller CA, Giardine BM, Barash Y, Hardison RC, Shi J, Blobel GA. Blood Adv. 2022 May 27:bloodadvances.2022007904. doi: 10.1182/bloodadvances.2022007904. Online ahead of print. PMID: 35622975
Extracellular Vesicle-Based Multianalyte Liquid Biopsy as a Diagnostic for Cancer. Lin AA, Nimgaonkar V, Issadore D, Carpenter EL. Annu Rev Biomed Data Sci. 2022 May 13. doi: 10.1146/annurev-biodatasci-122120-113218. Online ahead of print. PMID: 35562850
Trafficking and persistence of alloantigen-specific chimeric antigen receptor regulatory T cells in Cynomolgus macaque. Ellis GI, Coker KE, Winn DW, Deng MZ, Shukla D, Bhoj V, Milone MC, Wang W, Liu C, Naji A, Duran-Struuck R, Riley JL. Cell Rep Med. 2022 May 17;3(5):100614. doi: 10.1016/j.xcrm.2022.100614. Epub 2022 May 11. PMID: 35551746
Racism and perinatal health inequities research: where we have been and where we should go. Headen IE, Elovitz MA, Battarbee AN, Lo JO, Debbink MP. Am J Obstet Gynecol. 2022 May 18:S0002-9378(22)00377-5. doi: 10.1016/j.ajog.2022.05.033. Online ahead of print. PMID: 35597277
Case 16-2022: A 55-Year-Old Man with Fevers, Night Sweats, and a Mediastinal Mass. Fajgenbaum DC, Goiffon RJ, Soumerai JD, Harris CK. N Engl J Med. 2022 May 26;386(21):2036-2048. doi: 10.1056/NEJMcpc2115849. PMID: 35613025
Microbiota and maintenance of skin barrier function. Harris-Tryon TA, Grice EA. Science. 2022 May 27;376(6596):940-945. doi: 10.1126/science.abo0693. Epub 2022 May 26. PMID: 35617415
Highly restricted SARS-CoV-2 receptor expression and resistance to infection by primary human monocytes and monocyte-derived macrophages. Zankharia U, Yadav A, Yi Y, Hahn BH, Collman RG. J Leukoc Biol. 2022 May 27:10.1002/JLB.4COVA1121-579RR. doi: 10.1002/JLB.4COVA1121-579RR. Online ahead of print. PMID: 35621385
Antigenic and virological properties of an H3N2 variant that continues to dominate the 2021-22 Northern Hemisphere influenza season . Bolton MJ, Ort JT, McBride R, Swanson NJ, Wilson J, Awofolaju M, Furey C, Greenplate AR, Drapeau EM, Pekosz A, Paulson JC, Hensley SE. Cell Rep. 2022 May 31;39(9):110897. doi: 10.1016/j.celrep.2022.110897. PMID: 35649381
The ubiquitin ligase Cul5 regulates CD4⁺ T cell fate choice and allergic inflammation . Kumar B, Field NS, Kim DD, Dar AA, Chen Y, Suresh A, Pastore CF, Hung LY, Porter N, Sawada K, Shah P, Elbulok O, Moser EK, Herbert DR, Oliver PM. Nat Commun. 2022 May 19;13(1):2786. doi: 10.1038/s41467-022-30437-x. PMID: 35589717
"Every cell is an immune cell; contributions of non-hematopoietic cells to anti-helminth immunity". Inclan-Rico JM, Rossi HL, Herbert DR. Mucosal Immunol. 2022 May 10. doi: 10.1038/s41385-022-00518-7. Online ahead of print. PMID: 35538230

April 2022

Viral and Host Biomarkers of HIV Remission Post Treatment Interruption. Giron LB, Abdel-Mohsen M. Curr HIV/AIDS Rep. 2022 Apr 19. doi: 10.1007/s11904-022-00607-z. Online ahead of print.PMID: 35438384
Molecular imaging in management of colorectal metastases by the interventional oncologist. Hunt S, Zandifar A, Alavi A. Int J Hyperthermia. 2022;39(1):675-681. doi: 10.1080/02656736.2021.1998657.PMID: 35465814
Aducanumab-Related Amyloid-Related Imaging Abnormalities: Paean or Lament? Høilund-Carlsen PF, Werner TJ, Alavi A, Revheim ME. Clin Nucl Med. 2022 Apr 22. doi: 10.1097/RLU.0000000000004250. Online ahead of print.PMID: 35452007
Can Target-to-Background Ratio Measurement Lead to Detection and Accurate Quantification of Atherosclerosis With FDG PET? Likely Not . Alavi A, Werner TJ, Høilund-Carlsen PF, Revheim ME. Clin Nucl Med. 2022 Apr 5. doi: 10.1097/RLU.0000000000004131. Online ahead of print.PMID: 35384906
A review of different methods used for quantification and assessment of FDG-PET/CT in multiple myeloma. Zirakchian Zadeh M, Ayubcha C, Raynor WY, Werner TJ, Alavi A. Nucl Med Commun. 2022 Apr 1;43(4):378-391. doi: 10.1097/MNM.0000000000001528.PMID: 35102074
Long Noncoding RNAs That Function in Nutrition: Lnc-ing Nutritional Cues to Metabolic Pathways. Lovell CD, Anguera MC. Annu Rev Nutr. 2022 Apr 18. doi: 10.1146/annurev-nutr-062220-030244. Online ahead of print.PMID: 35436418
Herpes Simplex Virus (HSV)-2 Variation Contributes to Neurovirulence During Neonatal Infection. Hayes CK, Villota CK, McEnany FB, Cerón S, Awasthi S, Szpara ML, Friedman HM, Leib DA, Longnecker R, Weitzman MD, Akhtar LN. J Infect Dis. 2022 Apr 22:jiac151. doi: 10.1093/infdis/jiac151. Online ahead of print.PMID: 35451492
An mRNA vaccine to prevent genital herpes. Awasthi S, Friedman HM. Transl Res. 2022 Apr;242:56-65. doi: 10.1016/j.trsl.2021.12.006. Epub 2021 Dec 23.PMID: 34954087
β-Hydroxybutyrate suppresses colorectal cancer. Dmitrieva-Posocco O, Wong AC, Lundgren P, Golos AM, Descamps HC, Dohnalová L, Cramer Z, Tian Y, Yueh B, Eskiocak O, Egervari G, Lan Y, Liu J, Fan J, Kim J, Madhu B, Schneider KM, Khoziainova S, Andreeva N, Wang Q, Li N, Furth EE, Bailis W, Kelsen JR, Hamilton KE, Kaestner KH, Berger SL, Epstein JA, Jain R, Li M, Beyaz S, Lengner CJ, Katona BW, Grivennikov SI, Thaiss CA, Levy M. Nature. 2022 Apr 27. doi: 10.1038/s41586-022-04649-6. Online ahead of print.PMID: 35477756
The metabolic potential of the paediatric-onset multiple sclerosis gut microbiome. Mirza AI, Zhu F, Knox N, Forbes JD, Bonner C, Van Domselaar G, Bernstein CN, Graham M, Marrie RA, Hart J, Yeh EA, Arnold DL, Bar-Or A, O'Mahony J, Zhao Y, Hsiao W, Banwell B, Waubant E, Tremlett H. Mult Scler Relat Disord. 2022 Apr 23;63:103829. doi: 10.1016/j.msard.2022.103829. Online ahead of print.PMID: 35500534
Long-term efficacy and safety of siponimod in patients with secondary progressive multiple sclerosis: Analysis of EXPAND core and extension data up to >5 years. Cree BA, Arnold DL, Fox RJ, Gold R, Vermersch P, Benedict RH, Bar-Or A, Piani-Meier D, Rouyrre N, Ritter S, Kilaru A, Karlsson G, Giovannoni G, Kappos L. Mult Scler. 2022 Apr 5:13524585221083194. doi: 10.1177/13524585221083194. Online ahead of print.PMID: 35380078
BTK inhibition limits B-cell-T-cell interaction through modulation of B-cell metabolism: implications for multiple sclerosis therapy . Li R, Tang H, Burns JC, Hopkins BT, Le Coz C, Zhang B, de Barcelos IP, Romberg N, Goldstein AC, Banwell BL, Luning Prak ET, Mingueneau M, Bar-Or A. Acta Neuropathol. 2022 Apr;143(4):505-521. doi: 10.1007/s00401-022-02411-w. Epub 2022 Mar 18.PMID: 35303161
Paraneoplastic myasthenia gravis and pemphigus associated with follicular dendritic cell sarcoma leading to cardiorespiratory collapse in a 7-year-old. Lynch HM, Beslow LA, Treat JR, Corcoran A, Lin JH, Gunawardena N, Maris JM, Behrens EM. Pediatr Blood Cancer. 2022 Apr 29:e29723. doi: 10.1002/pbc.29723. Online ahead of print.PMID: 35484988
American College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 and Hyperinflammation in Pediatric COVID-19: Version 3. Henderson LA, Canna SW, Friedman KG, Gorelik M, Lapidus SK, Bassiri H, Behrens EM, Kernan KF, Schulert GS, Seo P, Son MBF, Tremoulet AH, VanderPluym C, Yeung RSM, Mudano AS, Turner AS, Karp DR, Mehta JJ. Arthritis Rheumatol. 2022 Apr;74(4):e1-e20. doi: 10.1002/art.42062. Epub 2022 Feb 3.PMID: 35118829
Single-cell multiomics reveals increased plasticity, resistant populations, and stem-cell-like blasts in KMT2A-rearranged leukemia. Chen C, Yu W, Alikarami F, Qiu Q, Chen CH, Flournoy J, Gao P, Uzun Y, Fang L, Davenport JW, Hu Y, Zhu Q, Wang K, Libbrecht C, Felmeister A, Rozich I, Ding YY, Hunger SP, Felix CA, Wu H, Brown PA, Guest EM, Barrett DM, Bernt KM, Tan K. Blood. 2022 Apr 7;139(14):2198-2211. doi: 10.1182/blood.2021013442.PMID: 34864916
Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression. Topfer SK, Feng R, Huang P, Ly LC, Martyn GE, Blobel GA, Weiss MJ, Quinlan KGR, Crossley M. Blood. 2022 Apr 7;139(14):2107-2118. doi: 10.1182/blood.2021014205.PMID: 35090172
PD-L1-PD-1 interactions limit effector regulatory T cell populations at homeostasis and during infection. Perry JA, Shallberg L, Clark JT, Gullicksrud JA, DeLong JH, Douglas BB, Hart AP, Lanzar Z, O'Dea K, Konradt C, Park J, Kuchroo JR, Grubaugh D, Zaretsky AG, Brodsky IE, Malefyt RW, Christian DA, Sharpe AH, Hunter CA. Nat Immunol. 2022 Apr 18. doi: 10.1038/s41590-022-01170-w. Online ahead of print.PMID: 35437326
The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade. Cucolo L, Chen Q, Qiu J, Yu Y, Klapholz M, Budinich KA, Zhang Z, Shao Y, Brodsky IE, Jordan MS, Gilliland DG, Zhang NR, Shi J, Minn AJ. Immunity. 2022 Apr 12;55(4):671-685.e10. doi: 10.1016/j.immuni.2022.03.007.PMID: 35417675
PSMA-targeting TGFβ-insensitive armored CAR T cells in metastatic castration-resistant prostate cancer: a phase 1 trial. Narayan V, Barber-Rotenberg JS, Jung IY, Lacey SF, Rech AJ, Davis MM, Hwang WT, Lal P, Carpenter EL, Maude SL, Plesa G, Vapiwala N, Chew A, Moniak M, Sebro RA, Farwell MD, Marshall A, Gilmore J, Lledo L, Dengel K, Church SE, Hether TD, Xu J, Gohil M, Buckingham TH, Yee SS, Gonzalez VE, Kulikovskaya I, Chen F, Tian L, Tien K, Gladney W, Nobles CL, Raymond HE; Prostate Cancer Cellular Therapy Program Investigators, Hexner EO, Siegel DL, Bushman FD, June CH, Fraietta JA, Haas NB. Nat Med. 2022 Apr;28(4):724-734. doi: 10.1038/s41591-022-01726-1. Epub 2022 Mar 21.PMID: 35314843
Human distal airways contain a multipotent secretory cell that can regenerate alveoli. Basil MC, Cardenas-Diaz FL, Kathiriya JJ, Morley MP, Carl J, Brumwell AN, Katzen J, Slovik KJ, Babu A, Zhou S, Kremp MM, McCauley KB, Li S, Planer JD, Hussain SS, Liu X, Windmueller R, Ying Y, Stewart KM, Oyster M, Christie JD, Diamond JM, Engelhardt JF, Cantu E, Rowe SM, Kotton DN, Chapman HA, Morrisey EE. Nature. 2022 Apr;604(7904):120-126. doi: 10.1038/s41586-022-04552-0. Epub 2022 Mar 30.PMID: 35355013
Subversion of Serotonin Receptor Signaling in Osteoblasts by Kynurenine Drives Acute Myeloid Leukemia . Galán-Díez M, Borot F, Ali AM, Zhao J, Gil-Iturbe E, Shan X, Luo N, Liu Y, Huang XP, Bisikirska B, Labella R, Kurland I, Roth BL, Quick M, Mukherjee S, Rabadán R, Carroll M, Raza A, Kousteni S. Cancer Discov. 2022 Apr 1;12(4):1106-1127. doi: 10.1158/2159-8290.CD-21-0692.PMID: 35046097
Transient expansion and myofibroblast conversion of adipogenic lineage precursors mediate bone marrow repair after radiation. Zhong L, Yao L, Holdreith N, Yu W, Gui T, Miao Z, Elkaim Y, Li M, Gong Y, Pacifici M, Maity A, Busch TM, Joeng KS, Cengel K, Seale P, Tong W, Qin L. JCI Insight. 2022 Apr 8;7(7):e150323. doi: 10.1172/jci.insight.150323.PMID: 35393948
A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program. Verma A, Tsao NL, Thomann LO, Ho YL, Iyengar SK, Luoh SW, Carr R, Crawford DC, Efird JT, Huffman JE, Hung A, Ivey KL, Levin MG, Lynch J, Natarajan P, Pyarajan S, Bick AG, Costa L, Genovese G, Hauger R, Madduri R, Pathak GA, Polimanti R, Voight B, Vujkovic M, Zekavat SM, Zhao H, Ritchie MD; VA Million Veteran Program COVID-19 Science Initiative, Chang KM, Cho K, Casas JP, Tsao PS, Gaziano JM, O'Donnell C, Damrauer SM, Liao KP. PLoS Genet. 2022 Apr 28;18(4):e1010113. doi: 10.1371/journal.pgen.1010113. eCollection 2022 Apr.PMID: 35482673
Coronary Artery Disease Risk of Familial Hypercholesterolemia Genetic Variants Independent of Clinically Observed Longitudinal Cholesterol Exposure. Clarke SL, Tcheandjieu C, Hilliard AT, Lee KM, Lynch J, Chang KM, Miller D, Knowles JW, O'Donnell C, Tsao PS, Rader DJ, Wilson PW, Sun YV, Gaziano JM, Assimes TL; VA Million Veteran Program. Circ Genom Precis Med. 2022 Apr;15(2):e003501. doi: 10.1161/CIRCGEN.121.003501. Epub 2022 Feb 10.PMID: 35143253
APOL1 Risk Variants, Acute Kidney Injury, and Death in Participants With African Ancestry Hospitalized With COVID-19 From the Million Veteran Program. Hung AM, Shah SC, Bick AG, Yu Z, Chen HC, Hunt CM, Wendt F, Wilson O, Greevy RA, Chung CP, Suzuki A, Ho YL, Akwo E, Polimanti R, Zhou J, Reaven P, Tsao PS, Gaziano JM, Huffman JE, Joseph J, Luoh SW, Iyengar S, Chang KM, Casas JP, Matheny ME, O'Donnell CJ, Cho K, Tao R, Susztak K, Robinson-Cohen C, Tuteja S, Siew ED; VA Million Veteran Program COVID-19 Science Initiative. JAMA Intern Med. 2022 Apr 1;182(4):386-395. doi: 10.1001/jamainternmed.2021.8538.PMID: 35089317
Pyrimidine inhibitors synergize with nucleoside analogues to block SARS-CoV-2. Schultz DC, Johnson RM, Ayyanathan K, Miller J, Whig K, Kamalia B, Dittmar M, Weston S, Hammond HL, Dillen C, Ardanuy J, Taylor L, Lee JS, Li M, Lee E, Shoffler C, Petucci C, Constant S, Ferrer M, Thaiss CA, Frieman MB, Cherry S. Nature. 2022 Apr;604(7904):134-140. doi: 10.1038/s41586-022-04482-x. Epub 2022 Feb 7.PMID: 35130559
Current Beliefs and Practices Regarding the Management of Obesity in Patients with Progressive Interstitial Lung Disease. Anderson MR, Aronson KI, Diamond JM, Christie JD, Singer JP. Ann Am Thorac Soc. 2022 Apr 15. doi: 10.1513/AnnalsATS.202201-019RL. Online ahead of print.PMID: 35427212
Human distal airways contain a multipotent secretory cell that can regenerate alveoli. Basil MC, Cardenas-Diaz FL, Kathiriya JJ, Morley MP, Carl J, Brumwell AN, Katzen J, Slovik KJ, Babu A, Zhou S, Kremp MM, McCauley KB, Li S, Planer JD, Hussain SS, Liu X, Windmueller R, Ying Y, Stewart KM, Oyster M, Christie JD, Diamond JM, Engelhardt JF, Cantu E, Rowe SM, Kotton DN, Chapman HA, Morrisey EE. Nature. 2022 Apr;604(7904):120-126. doi: 10.1038/s41586-022-04552-0. Epub 2022 Mar 30.PMID: 35355013
Saliva vs upper respiratory swabs: Equivalent for SARS-CoV-2 university screening while saliva positivity is prolonged post-symptom onset in COVID-19 hospitalized patients . El-Sharkawy F, Tang CN, Fitzgerald AS, Khatib LA, Graham-Wooten J, Glaser L, Collman RG, Van Deerlin VM, Herlihy SE. J Mol Diagn. 2022 Apr 27:S1525-1578(22)00104-0. doi: 10.1016/j.jmoldx.2022.03.012. Online ahead of print.PMID: 35489695
Epigenetic Landscape of HIV-1 Infection in Primary Human Macrophage. Lu F, Zankharia U, Vladimirova O, Yi Y, Collman RG, Lieberman PM. J Virol. 2022 Apr 13;96(7):e0016222. doi: 10.1128/jvi.00162-22. Epub 2022 Mar 23.PMID: 35319230
Editorial: Antimicrobial Peptides: Molecular Design, Structure-Function Relationship, and Biosynthesis Optimization . Hao Y, Wang J, de la Fuente-Nunez C, Franco OL. Front Microbiol. 2022 Apr 11;13:888540. doi: 10.3389/fmicb.2022.888540. eCollection 2022.PMID: 35495692
Autonomous Treatment of Bacterial Infections in Vivo Using Antimicrobial Micro- and Nanomotors . Arqué X, Torres MDT, Patiño T, Boaro A, Sánchez S, de la Fuente-Nunez C. ACS Nano. 2022 Apr 29. doi: 10.1021/acsnano.1c11013. Online ahead of print.PMID: 35486889
Detection of SARS-CoV-2 with RAPID: A prospective cohort study. Torres MDT, de Lima LF, Ferreira AL, de Araujo WR, Callahan P, Dávila A Jr, Abella BS, de la Fuente-Nunez C. iScience. 2022 Apr 15;25(4):104055. doi: 10.1016/j.isci.2022.104055. Epub 2022 Mar 11.PMID: 35291265
Subcutaneous Implantable Cardioverter-defibrillator Explantation-A Single Tertiary Center Experience . Pothineni NVK, Cherian T, Patel N, Smietana J, Frankel DS, Deo R, Epstein AE, Marchlinski FE, Schaller RD. J Innov Card Rhythm Manag. 2022 Apr 15;13(4):4947-4953. doi: 10.19102/icrm.2022.130407. eCollection 2022 Apr.PMID: 35474857
Effect of Transcutaneous Magnetic Stimulation in Patients With Ventricular Tachycardia Storm: A Randomized Clinical Trial. Markman TM, Pothineni NVK, Zghaib T, Smietana J, McBride D, Amankwah NA, Linn KA, Kumareswaran R, Hyman M, Arkles J, Santangeli P, Schaller RD, Supple GE, Frankel DS, Deo R, Lin D, Riley MP, Epstein AE, Callans DJ, Marchlinski FE, Hamilton R, Nazarian S. JAMA Cardiol. 2022 Apr 1;7(4):445-449. doi: 10.1001/jamacardio.2021.6000.PMID: 35171197
Use of elexacaftor/tezacaftor/ivacaftor among cystic fibrosis lung transplant recipients. Ramos KJ, Guimbellot JS, Valapour M, Bartlett LE, Wai TH, Goss CH, Pilewski JM, Faro A, Diamond JM; CFLTC Study Group. J Cyst Fibros. 2022 Apr 23:S1569-1993(22)00098-4. doi: 10.1016/j.jcf.2022.04.009. Online ahead of print.PMID: 35474016
Don't Inhale: Acute Respiratory Distress Syndrome Risk and Tobacco Exposure in Patients with Sepsis. Diamond JM. Am J Respir Crit Care Med. 2022 Apr 15;205(8):866-867. doi: 10.1164/rccm.202201-0034ED.PMID: 35130469
CD47-SIRPα Checkpoint Disruption in Metastases Requires Tumor-Targeting Antibody for Molecular and Engineered Macrophage Therapies. Andrechak JC, Dooling LJ, Tobin MP, Zhang W, Hayes BH, Lee JY, Jin X, Irianto J, Discher DE. Cancers (Basel). 2022 Apr 11;14(8):1930. doi: 10.3390/cancers14081930.PMID: 35454837
Prevalence of Prodromal Symptoms of Parkinson's Disease in the Late Middle-Aged Population . Roos DS, Klein M, Deeg DJH, Doty RL, Berendse HW. .J Parkinsons Dis. 2022;12(3):967-974. doi: 10.3233/JPD-213007.PMID: 35180132
Second trimester short cervix is associated with decreased abundance of cervicovaginal lipid metabolites. Gerson KD, Yang N, Anton L, Levy M, Ravel J, Elovitz MA, Burris HH. Am J Obstet Gynecol. 2022 Apr 22:S0002-9378(22)00310-6. doi: 10.1016/j.ajog.2022.04.031. Online ahead of print.PMID: 35469813
Effectiveness of a Text-Based Gamification Intervention to Improve Physical Activity Among Postpartum Individuals With Hypertensive Disorders of Pregnancy: A Randomized Clinical Trial. Lewey J, Murphy S, Zhang D, Putt ME, Elovitz MA, Riis V, Patel MS, Levine LD. .JAMA Cardiol. 2022 Apr 20:e220553. doi: 10.1001/jamacardio.2022.0553. Online ahead of print. PMID: 35442393
Association of COVID-19 and Endemic Systemic Racism With Postpartum Anxiety and Depression Among Black Birthing Individuals. Njoroge WFM, White LK, Waller R, Forkpa M, Himes MM, Morgan K, Seidlitz J, Chaiyachati BH, Barzilay R, Kornfield SL, Parish-Morris J, Rodriguez Y, Riis V, Burris HH, Elovitz MA, Gur RE. JAMA Psychiatry. 2022 Apr 13:e220597. doi: 10.1001/jamapsychiatry.2022.0597. Online ahead of print.PMID: 35416928
COVID-19 vaccination and HIV-1 acquisition. Logunov DY, Livermore DM, Ornelles DA, Bayer W, Marques E, Czerkinsky C, Dolzhikova IV, Ertl HC. Lancet. 2022 Apr 9;399(10333):e34-e35. doi: 10.1016/S0140-6736(22)00332-4.PMID: 35397866
Editorial: Deciphering the Microbiome-Immunity-Cancer Axis. Chen X, Jin C, Facciabene A, Guo X, Zhang Y. Front Immunol. 2022 Apr 14;13:897811. doi: 10.3389/fimmu.2022.897811. eCollection 2022.PMID: 35493451
Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy . Smith M, Dai A, Ghilardi G, Amelsberg KV, Devlin SM, Pajarillo R, Slingerland JB, Beghi S, Herrera PS, Giardina P, Clurman A, Dwomoh E, Armijo G, Gomes ALC, Littmann ER, Schluter J, Fontana E, Taur Y, Park JH, Palomba ML, Halton E, Ruiz J, Jain T, Pennisi M, Afuye AO, Perales MA, Freyer CW, Garfall A, Gier S, Nasta S, Landsburg D, Gerson J, Svoboda J, Cross J, Chong EA, Giralt S, Gill SI, Riviere I, Porter DL, Schuster SJ, Sadelain M, Frey N, Brentjens RJ, June CH, Pamer EG, Peled JU, Facciabene A, van den Brink MRM, Ruella M. Nat Med. 2022 Apr;28(4):713-723. doi: 10.1038/s41591-022-01702-9. Epub 2022 Mar 14.PMID: 35288695
Increased mTORC2 pathway activation in lymph nodes of iMCD-TAFRO . Phillips AD, Kakkis JJ, Tsao PY, Pierson SK, Fajgenbaum DC. J Cell Mol Med. 2022 Apr 30. doi: 10.1111/jcmm.17251. Online ahead of print.PMID: 35488725
The lymph node transcriptome of unicentric and idiopathic multicentric Castleman disease. Horna P, King RL, Jevremovic D, Fajgenbaum DC, Dispenzieri A. Haematologica. 2022 Apr 28. doi: 10.3324/haematol.2021.280370. Online ahead of print.PMID: 35484648
Bone marrow findings of idiopathic Multicentric Castleman disease: A histopathologic analysis and systematic literature review. Belyaeva E, Rubenstein A, Pierson SK, Dalldorf D, Frank D, Lim MS, Fajgenbaum DC. Hematol Oncol. 2022 Apr;40(2):191-201. doi: 10.1002/hon.2969. Epub 2022 Feb 18.PMID: 35104370
Guideline to Practice: Diagnosis and Management of Barrett's Esophagus: An Updated ACG Guideline. Shaheen NJ, Falk GW, Iyer PG, Souza RF, Wani S. Am J Gastroenterol. 2022 Apr 15. doi: 10.14309/ajg.0000000000001788. Online ahead of print.PMID: 35467555
Diagnosis and Management of Barrett's Esophagus: An Updated ACG Guideline. Shaheen NJ, Falk GW, Iyer PG, Souza RF, Yadlapati RH, Sauer BG, Wani S. Am J Gastroenterol. 2022 Apr 1;117(4):559-587. doi: 10.14309/ajg.0000000000001680.PMID: 35354777
Can FLIP guide therapy in idiopathic esophagogastric junction outflow obstruction? Beveridge CA, Triggs JR, Thanawala SU, Ahuja NK, Falk GW, Benitez AJ, Lynch KL. Dis Esophagus. 2022 Apr 19;35(4):doab077. doi: 10.1093/dote/doab077.PMID: 34864928
The clinical aspect of NTRK-fusions in pediatric papillary thyroid cancer. Ricarte-Filho JC, Halada S, O'Neill A, Casado-Medrano V, Laetsch TW, Franco AT, Bauer AJ. Cancer Genet. 2022 Apr;262-263:57-63. doi: 10.1016/j.cancergen.2022.01.002. Epub 2022 Jan 19.PMID: 35092884
Fusion Oncogenes Are Associated With Increased Metastatic Capacity and Persistent Disease in Pediatric Thyroid Cancers. Franco AT, Ricarte-Filho JC, Isaza A, Jones Z, Jain N, Mostoufi-Moab S, Surrey L, Laetsch TW, Li MM, DeHart JC, Reichenberger E, Taylor D, Kazahaya K, Adzick NS, Bauer AJ. .J Clin Oncol. 2022 Apr 1;40(10):1081-1090. doi: 10.1200/JCO.21.01861. Epub 2022 Jan 11.PMID: 35015563
Initial analysis of viral dynamics and circulating viral variants during the mRNA-1273 Phase 3 COVE trial . Pajon R, Paila YD, Girard B, Dixon G, Kacena K, Baden LR, El Sahly HM, Essink B, Mullane KM, Frank I, Denhan D, Kerwin E, Zhao X, Ding B, Deng W, Tomassini JE, Zhou H, Leav B, Schödel F; COVE Trial Consortium. Nat Med. 2022 Apr;28(4):823-830. doi: 10.1038/s41591-022-01679-5. Epub 2022 Feb 10.PMID: 35145311
Methotrexate promotes recovery of arthritis-induced alveolar bone loss and modifies the composition of the oral-gut microbiota. Almeida de Arruda JA, Corrêa JD, Singh Y, Oliveira SR, Machado CC, Schneider AH, Medeiros JD, Fernandes GR, Macari S, Barrioni BR, de Souza Santos M, Duffles LF, Imoto Nakaya HT, Fukada SY, Graves DT, Cunha FQ, Silva TA. Anaerobe. 2022 Apr 28:102577. doi: 10.1016/j.anaerobe.2022.102577. Online ahead of print.PMID: 35490916
Zoonotic origin of the human malaria parasite Plasmodium malariae from African apes. Plenderleith LJ, Liu W, Li Y, Loy DE, Mollison E, Connell J, Ayouba A, Esteban A, Peeters M, Sanz CM, Morgan DB, Wolfe ND, Ulrich M, Sachse A, Calvignac-Spencer S, Leendertz FH, Shaw GM, Hahn BH, Sharp PM. Nat Commun. 2022 Apr 6;13(1):1868. doi: 10.1038/s41467-022-29306-4.PMID: 35387986
Maladaptive innate immune training of myelopoiesis links inflammatory comorbidities. Li X, Wang H, Yu X, Saha G, Kalafati L, Ioannidis C, Mitroulis I, Netea MG, Chavakis T, Hajishengallis G. Cell. 2022 Apr 21:S0092-8674(22)00393-2. doi: 10.1016/j.cell.2022.03.043. Online ahead of print.PMID: 35483374
Transarterial Embolization Modulates the Immune Response within Target and Nontarget Hepatocellular Carcinomas in a Rat Model. Tischfield DJ, Gurevich A, Johnson O, Gatmaytan I, Nadolski GJ, Soulen MC, Kaplan DE, Furth E, Hunt SJ, Gade TPF. Radiology. 2022 Apr;303(1):215-225. doi: 10.1148/radiol.211028. Epub 2022 Jan 11.PMID: 35014906
MicroRNA-29a attenuates CD8 T cell exhaustion and induces memory-like CD8 T cells during chronic infection. Stelekati E, Cai Z, Manne S, Chen Z, Beltra JC, Buchness LA, Leng X, Ristin S, Nzingha K, Ekshyyan V, Niavi C, Abdel-Hakeem MS, Ali MA, Drury S, Lau CW, Gao Z, Ban Y, Zhou SK, Ansel KM, Kurachi M, Jordan MS, Villarino AV, Ngiow SF, Wherry EJ. Proc Natl Acad Sci U S A. 2022 Apr 26;119(17):e2106083119. doi: 10.1073/pnas.2106083119. Epub 2022 Apr 21.PMID: 35446623
Engineered cellular immunotherapies in cancer and beyond. Finck AV, Blanchard T, Roselle CP, Golinelli G, June CH. Nat Med. 2022 Apr;28(4):678-689. doi: 10.1038/s41591-022-01765-8. Epub 2022 Apr 19.PMID: 35440724
Next-Generation CAR T-cell Therapies. Young RM, Engel NW, Uslu U, Wellhausen N, June CH. Cancer Discov. 2022 Apr 12:OF1-OF14. doi: 10.1158/2159-8290.CD-21-1683. Online ahead of print.PMID: 35417527
VE-cadherin enables trophoblast endovascular invasion and spiral artery remodeling during placental development . Sung DC, Chen X, Chen M, Yang J, Schultz S, Babu A, Xu Y, Gao S, Stevenson Keller TC, Mericko P, Lee M, Yang Y, Scallan JP, Kahn ML. Elife. 2022 Apr 29;11:e77241. doi: 10.7554/eLife.77241. Online ahead of print.PMID: 35486098
The Association Between Proton Pump Inhibitor Exposure and Key Liver-Related Outcomes in Patients With Cirrhosis: A Veterans Affairs Cohort Study. Mahmud N, Serper M, Taddei TH, Kaplan DE. Gastroenterology. 2022 Apr 6:S0016-5085(22)00352-3. doi: 10.1053/j.gastro.2022.03.052. Online ahead of print.PMID: 35398042
Current challenges and opportunities in the care of patients with fibrodysplasia ossificans progressiva (FOP): an international, multi-stakeholder perspective. Pignolo RJ, Bedford-Gay C, Cali A, Davis M, Delai PLR, Gonzales K, Hixson C, Kent A, Newport H, Robert M, Scott C, Kaplan FS. Orphanet J Rare Dis. 2022 Apr 18;17(1):168. doi: 10.1186/s13023-022-02224-w.PMID: 35436894
Yield of upper gastrointestinal screening in colonic adenomatous polyposis of unknown etiology: a multicenter study . Farah F, Patel SG, Espinoza JM, Jensen N, Katona BW, Muller C, Kupfer SS, Weiss JM, Hinton A, Stanich PP. Endosc Int Open. 2022 Apr 14;10(4):E528-E533. doi: 10.1055/a-1784-0166. eCollection 2022 Apr.PMID: 35433207
Management of Relapsed Cutaneous T-Cell Lymphoma Following Allogeneic Hematopoietic Stem Cell Transplantation: Review with Representative Patient Case. Weiner DM, Lewis DJ, Spaccarelli NG, Clark RA, Nasta SD, Loren AW, Rook AH, Kim EJ. Dermatol Ther. 2022 Apr 27:e15538. doi: 10.1111/dth.15538. Online ahead of print.PMID: 35477952
Parapsoriasis-A Diagnosis with an Identity Crisis: A Narrative Review . Chairatchaneeboon M, Thanomkitti K, Kim EJ. Dermatol Ther (Heidelb). 2022 Apr 15. doi: 10.1007/s13555-022-00716-y. Online ahead of print.PMID: 35426607
The Women of FOCIS: Promoting Equality and Inclusiveness in a Professional Federation of Clinical Immunology Societies . Reed EF, Chong AS, Levings MK, Mutrie C, Laufer TM, Roncarolo MG, Sykes M. Front Immunol. 2022 Apr 4;13:816535. doi: 10.3389/fimmu.2022.816535. eCollection 2022.PMID: 35444663
2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Kawasaki Disease. Gorelik M, Chung SA, Ardalan K, Binstadt BA, Friedman K, Hayward K, Imundo LF, Lapidus SK, Kim S, Son MB, Sule S, Tremoulet AH, Van Mater H, Yildirim-Toruner C, Langford CA, Maz M, Abril A, Guyatt G, Archer AM, Conn DL, Full KA, Grayson PC, Ibarra MF, Merkel PA, Rhee RL, Seo P, Stone JH, Sundel RP, Vitobaldi OI, Warner A, Byram K, Dua AB, Husainat N, James KE, Kalot M, Lin YC, Springer JM, Turgunbaev M, Villa-Forte A, Turner AS, Mustafa RA. Arthritis Care Res (Hoboken). 2022 Apr;74(4):538-548. doi: 10.1002/acr.24838. Epub 2022 Mar 7.PMID: 35257507
Cytosolic Delivery of Small Protein Scaffolds Enables Efficient Inhibition of Ras and Myc. Chan A, Wang HH, Haley RM, Song C, Gonzalez-Martinez D, Bugaj L, Mitchell MJ, Tsourkas A. Mol Pharm. 2022 Apr 4;19(4):1104-1116. doi: 10.1021/acs.molpharmaceut.1c00798. Epub 2022 Feb 28.PMID: 35225618
Circulating Donor Lung-specific Exosome Profiles Enable Noninvasive Monitoring of Acute Rejection in a Rodent Orthotopic Lung Transplantation Model. Habertheuer A, Ram C, Schmierer M, Chatterjee S, Hu R, Freas A, Zielinski P, Rogers W, Silvestro EM, McGrane M, Moore JS, Korutla L, Siddiqui S, Xin Y, Rizi R, Qin Tao J, Kreisel D, Naji A, Ochiya T, Vallabhajosyula P. Transplantation. 2022 Apr 1;106(4):754-766. doi: 10.1097/TP.0000000000003820.PMID: 33993180
Temporal Outcomes after Rituximab Therapy for Pemphigus Vulgaris. Tovanabutra N, Bax CE, Feng R, Kushner CJ, Payne AS. J Invest Dermatol. 2022 Apr;142(4):1058-1064.e7. doi: 10.1016/j.jid.2021.09.013. Epub 2021 Oct 26.PMID: 34710389
Salvage therapy with basiliximab and etanercept for severe steroid-refractory acute graft-versus-host disease. Freyer CW, Gier S, Carulli A, Gill SI, Hexner EO, Loren AW, Martin ME, Porter DL. Am J Hematol. 2022 Apr 12. doi: 10.1002/ajh.26568. Online ahead of print.PMID: 35413140
Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy. Smith M, Dai A, Ghilardi G, Amelsberg KV, Devlin SM, Pajarillo R, Slingerland JB, Beghi S, Herrera PS, Giardina P, Clurman A, Dwomoh E, Armijo G, Gomes ALC, Littmann ER, Schluter J, Fontana E, Taur Y, Park JH, Palomba ML, Halton E, Ruiz J, Jain T, Pennisi M, Afuye AO, Perales MA, Freyer CW, Garfall A, Gier S, Nasta S, Landsburg D, Gerson J, Svoboda J, Cross J, Chong EA, Giralt S, Gill SI, Riviere I, Porter DL, Schuster SJ, Sadelain M, Frey N, Brentjens RJ, June CH, Pamer EG, Peled JU, Facciabene A, van den Brink MRM, Ruella M. Nat Med. 2022 Apr;28(4):713-723. doi: 10.1038/s41591-022-01702-9. Epub 2022 Mar 14.PMID: 35288695
Mitogen-Activated Protein Kinase Inhibitor Selumetinib Fails to Increase the Complete Response Rate of Radioactive Iodine Alone in High-Risk Differentiated Thyroid Cancer: Lessons From the Phase III ASTRA Study . Brose MS, Pryma DA, Newbold KL. J Clin Oncol. 2022 Apr 29:JCO2200556. doi: 10.1200/JCO.22.00556. Online ahead of print.PMID: 35486879
Comprehensive nutrient consumption estimation and metabolic profiling during ketogenic diet and relationship with myocardial glucose uptake on FDG-PET. Selvaraj S, Seidelmann SB, Soni M, Bhattaru A, Margulies KB, Shah SH, Dugyala S, Qian C, Pryma DA, Arany Z, Kelly DP, Chirinos JA, Bravo PE. Eur Heart J Cardiovasc Imaging. 2022 Apr 2:jeac031. doi: 10.1093/ehjci/jeac031. Online ahead of print.PMID: 35366303
Investigating the relationships between resilience, autism-related quantitative traits, and mental health outcomes among adults during the COVID-19 pandemic . Taylor SC, Smernoff ZL, Rajan M, Steeman S, Gehringer BN, Dow HC, Barzilay R, Rader DJ, Bucan M, Almasy L, Brodkin ES. J Psychiatr Res. 2022 Apr;148:250-257. doi: 10.1016/j.jpsychires.2022.01.046. Epub 2022 Jan 29.PMID: 35151216
Coronary Artery Disease Risk of Familial Hypercholesterolemia Genetic Variants Independent of Clinically Observed Longitudinal Cholesterol Exposure. Clarke SL, Tcheandjieu C, Hilliard AT, Lee KM, Lynch J, Chang KM, Miller D, Knowles JW, O'Donnell C, Tsao PS, Rader DJ, Wilson PW, Sun YV, Gaziano JM, Assimes TL; VA Million Veteran Program. Circ Genom Precis Med. 2022 Apr;15(2):e003501. doi: 10.1161/CIRCGEN.121.003501. Epub 2022 Feb 10.PMID: 35143253
Web of Science's Citation Median Metrics Overcome the Major Constraints of the Journal Impact Factor. Daugherty A, Hegele RA, Lu HS, Mackman N, Rader DJ, Weber C.Arterioscler Thromb Vasc Biol. 2022 Apr;42(4):367-371. doi: 10.1161/ATVBAHA.122.317426. Epub 2022 Feb 3.PMID: 35109675
Genetic obstacles to developing and tolerizing human B cells. Nguyen K, Alsaati N, Le Coz C, Romberg N. WIREs Mech Dis. 2022 Apr 5:e1554. doi: 10.1002/wsbm.1554. Online ahead of print.PMID: 35384409
Kikuchi-Fujimoto disease is mediated by an aberrant type I interferon response . Li EY, Xu J, Nelson ND, Teachey DT, Tan K, Romberg N, Behrens E, Pillai V. Mod Pathol. 2022 Apr;35(4):462-469. doi: 10.1038/s41379-021-00992-7. Epub 2021 Dec 24.PMID: 34952944
Identification of germline monoallelic mutations in IKZF2 in patients with immune dysregulation. Shahin T, Mayr D, Shoeb MR, Kuehn HS, Hoeger B, Giuliani S, Gawriyski LM, Petronczki ÖY, Hadjadj J, Bal SK, Zoghi S, Haimel M, Jimenez Heredia R, Boutboul D, Triebwasser MP, Rialland-Battisti F, Costedoat Chalumeau N, Quartier P, Tangye SG, Fleisher TA, Rezaei N, Romberg N, Latour S, Varjosalo M, Halbritter F, Rieux-Laucat F, Castanon I, Rosenzweig SD, Boztug K. Blood Adv. 2022 Apr 12;6(7):2444-2451. doi: 10.1182/bloodadvances.2021006367.PMID: 34920454
Resistance to mogamulizumab is associated with loss of CCR4 in Cutaneous T-cell Lymphoma. Beygi S, Duran GE, Fernandez-Pol S, Rook AH, Kim YH, Khodadoust MS. Blood. 2022 Apr 18:blood.2021014468. doi: 10.1182/blood.2021014468. Online ahead of print.PMID: 35436328
Post-treatment gene scores support histologic and endoscopic response thresholds in eosinophilic esophagitis. Ruffner MA, Cotton CC, Dellon ES. Am J Gastroenterol. 2022 Apr 26. doi: 10.14309/ajg.0000000000001802. Online ahead of print.PMID: 35470295
Expression of Human Interleukin 8 in Mice Alters Their Natural Behaviors. Tian Z, Shofer FS, Sandroni AZ, Zhao L, Scanzello CR, Zhang Y. J Inflamm Res. 2022 Apr 13;15:2413-2424. doi: 10.2147/JIR.S355669. eCollection 2022.PMID: 35444450
Azadirachta indica A. Juss bark extract and its Nimbin isomers restrict β-coronaviral infection and replication . Sarkar L, Oko L, Gupta S, Bubak AN, Das B, Gupta P, Safiriyu AA, Singhal C, Neogi U, Bloom D, Banerjee A, Mahalingam R, Cohrs RJ, Koval M, Shindler KS, Pal D, Nagel M, Sarma JD. Virology. 2022 Apr;569:13-28. doi: 10.1016/j.virol.2022.01.002. Epub 2022 Feb 15.PMID: 35219218
The impact of head and neck radiotherapy on salivary flow and quality of life: Results of the ORARAD study. Lin A, Helgeson ES, Treister NS, Schmidt BL, Patton LL, Elting LS, Lalla RV, Brennan MT, Sollecito TP. Oral Oncol. 2022 Apr;127:105783. doi: 10.1016/j.oraloncology.2022.105783. Epub 2022 Feb 26.PMID: 35231809
MyD88-dependent TLR signaling oppositely regulates hematopoietic progenitor and stem cell formation in the embryo. Bennett LF, Mumau MD, Li Y, Speck NA. Development. 2022 Apr 15;149(8):dev200025. doi: 10.1242/dev.200025. Epub 2022 Feb 11.PMID: 35043940
Nasopharyngeal airway dual-transcriptome of infants with severe bronchiolitis and risk of childhood asthma: A multicenter prospective study. Zhu Z, Camargo CA Jr, Raita Y, Freishtat RJ, Fujiogi M, Hahn A, Mansbach JM, Spergel JM, Pérez-Losada M, Hasegawa K. J Allergy Clin Immunol. 2022 Apr 25:S0091-6749(22)00556-5. doi: 10.1016/j.jaci.2022.04.017. Online ahead of print.PMID: 35483507
Disease burden and unmet need in eosinophilic esophagitis. Bredenoord AJ, Patel K, Schoepfer AM, Dellon ES, Chehade M, Aceves SS, Spergel JM, Shumel B, Deniz Y, Rowe PJ, Jacob-Nara JA. Am J Gastroenterol. 2022 Apr 13. doi: 10.14309/ajg.0000000000001777. Online ahead of print.PMID: 35417421
Esophageal remodeling in Eosinophilic Esophagitis: Relationships to luminal captured biomarkers of inflammation and periostin. Muir A, Ackerman SJ, Pan Z, Benitez A, Burger C, Spergel JM, Furuta GT, Rothman J, Wilkins BJ, Arnold M, Dolinsky L, Grozdanovic M, Menard-Katcher C. J Allergy Clin Immunol. 2022 Apr 8:S0091-6749(22)00444-4. doi: 10.1016/j.jaci.2022.03.022. Online ahead of print.PMID: 35405206
Novel questionnaires for assessing signs and symptoms of eosinophilic esophagitis in children. Kamat S, Yaworsky A, Guillemin I, Krohe M, Litcher-Kelly L, McLafferty M, Lamoureux RE, Lowe C, Chehade M, Spergel JM, Weinfurt K, Turner-Bowker DM .J Allergy Clin Immunol Pract. 2022 Apr 7:S2213-2198(22)00331-2. doi: 10.1016/j.jaip.2022.02.049. Online ahead of print.PMID: 35398552
Live imaging of the Cryptosporidium parvum life cycle reveals direct development of male and female gametes from type I meronts. English ED, Guérin A, Tandel J, Striepen B. PLoS Biol. 2022 Apr 18;20(4):e3001604. doi: 10.1371/journal.pbio.3001604. eCollection 2022 Apr.PMID: 35436284
Inhibition of the Sec61 translocon overcomes cytokine-induced glucocorticoid resistance in T-cell acute lymphoblastic leukaemia. Meyer LK, Delgado-Martin C, Sharp PP, Huang BJ, McMinn D, Vincent TL, Ryan T, Horton TM, Wood BL, Teachey DT, Taunton J, Kirk CJ, Hermiston ML. Br J Haematol. 2022 Apr 17. doi: 10.1111/bjh.18181. Online ahead of print.PMID: 35434798
JAK3 mutations and mitochondrial apoptosis resistance in T-cell acute lymphoblastic leukemia . Bodaar K, Yamagata N, Barthe A, Landrigan J, Chonghaile TN, Burns M, Stevenson KE, Devidas M, Loh ML, Hunger SP, Wood B, Silverman LB, Teachey DT, Meijerink JP, Letai A, Gutierrez A. Leukemia. 2022 Apr 11. doi: 10.1038/s41375-022-01558-5. Online ahead of print.PMID: 35411095
A minimal monitoring approach for the treatment of hepatitis C virus infection (ACTG A5360 [MINMON]): a phase 4, open-label, single-arm trial. Solomon SS, Wagner-Cardoso S, Smeaton L, Sowah LA, Wimbish C, Robbins G, Brates I, Scello C, Son A, Avihingsanon A, Linas B, Anthony D, Nunes EP, Kliemann DA, Supparatpinyo K, Kityo C, Tebas P, Bennet JA, Santana-Bagur J, Benson CA, Van Schalkwyk M, Cheinquer N, Naggie S, Wyles D, Sulkowski M. Lancet Gastroenterol Hepatol. 2022 Apr;7(4):307-317. doi: 10.1016/S2468-1253(21)00397-6. Epub 2022 Jan 10. PMID: 35026142
Targeting CD123 in blastic plasmacytoid dendritic cell neoplasm using allogeneic anti-CD123 CAR T cells . Cai T, Gouble A, Black KL, Skwarska A, Naqvi AS, Taylor D, Zhao M, Yuan Q, Sugita M, Zhang Q, Galetto R, Filipe S, Cavazos A, Han L, Kuruvilla V, Ma H, Weng C, Liu CG, Liu X, Konoplev S, Gu J, Tang G, Su X, Al-Atrash G, Ciurea S, Neelapu SS, Lane AA, Kantarjian H, Guzman ML, Pemmaraju N, Smith J, Thomas-Tikhonenko A, Konopleva M. Nat Commun. 2022 Apr 28;13(1):2228. doi: 10.1038/s41467-022-29669-8. PMID: 35484100
Superoxide dismutase-loaded porous polymersomes as highly efficient antioxidant nanoparticles targeting synovium for osteoarthritis therapy . Gui T, Luo L, Chhay B, Zhong L, Wei Y, Yao L, Yu W, Li J, Nelson CL, Tsourkas A, Qin L, Cheng Z. Biomaterials. 2022 Apr;283:121437. doi: 10.1016/j.biomaterials.2022.121437. Epub 2022 Feb 23. PMID: 35247635
Molecular therapies and vaccines face the challenges of emerging infectious diseases . Patel A, Weiner D, Xiao W, Baker A, Sanders N. Mol Ther. 2022 Apr 15;30(5):1789-90. doi: 10.1016/j.ymthe.2022.04.003. Online ahead of print. PMID: 35429438
DRUMMER-Rapid detection of RNA modifications through comparative nanopore sequencing . Abebe JS, Price AM, Hayer KE, Mohr I, Weitzman MD, Wilson AC, Depledge DP. Bioinformatics. 2022 Apr 15:btac274. doi: 10.1093/bioinformatics/btac274. Online ahead of print. PMID: 35426900
Safety and Efficacy of Lenabasum, a Cannabinoid Receptor Type 2 Agonist, in Dermatomyositis Patients with Refractory Skin Disease A Randomized Clinical Trial. Werth VP, Hejazi E, Pena SM, Haber J, Zeidi M, Reddy N, Okawa J, Feng R, Bashir MM, Gebre K, Jadoo AS, Concha JSS, Dgetluck N, Constantine S, White B. J Invest Dermatol. 2022 Apr 28:S0022-202X(22)00295-0. doi: 10.1016/j.jid.2022.03.029. Online ahead of print. PMID: 35490744
Biological impact of iberdomide in patients with active systemic lupus erythematosus. Lipsky PE, Vollenhoven RV, Dörner T, Werth VP, Merrill JT, Furie R, Petronijevic M, Velasco Zamora B, Majdan M, Irazoque-Palazuelos F, Terbrueggen R, Delev N, Weiswasser M, Korish S, Stern M, Hersey S, Ye Y, Gaudy A, Liu Z, Gagnon R, Tang S, Schafer PH. Ann Rheum Dis. 2022 Apr 27:annrheumdis-2022-222212. doi: 10.1136/annrheumdis-2022-222212. Online ahead of print. PMID: 35477518
Preliminary definition of cutaneous flare in dermatomyositis: A retrospective review. Dan J, Afarideh M, Sprow G, Keyes E, Diaz D, Vazquez T, Kodali N, Werth VP. J Am Acad Dermatol. 2022 Apr 2:S0190-9622(22)00546-1. doi: 10.1016/j.jaad.2022.03.054. Online ahead of print. PMID: 35381299
Increased CD69+CCR7+ circulating activated T cells and STAT3 expression in cutaneous lupus erythematosus patients recalcitrant to antimalarials . Zeidi M, Chen KL, Patel J, Desai K, Kim HJ, Chakka S, Lim R, Werth VP. Lupus. 2022 Apr;31(4):472-481. doi: 10.1177/09612033221084093. Epub 2022 Mar 8. PMID: 35258358
Sclerotic skin disease development following COVID-19 vaccination . Sprow G, Dan J, Abbott J, Jiang A, Diaz D, Vazquez T, Kodali N, Werth VP. JAAD Case Rep. 2022 Apr;22:74-77. doi: 10.1016/j.jdcr.2022.02.008. Epub 2022 Feb 23. PMID: 35224171
MicroRNA-29a attenuates CD8 T cell exhaustion and induces memory-like CD8 T cells during chronic infection. Stelekati E, Cai Z, Manne S, Chen Z, Beltra JC, Buchness LA, Leng X, Ristin S, Nzingha K, Ekshyyan V, Niavi C, Abdel-Hakeem MS, Ali MA, Drury S, Lau CW, Gao Z, Ban Y, Zhou SK, Ansel KM, Kurachi M, Jordan MS, Villarino AV, Ngiow SF, Wherry EJ. Proc Natl Acad Sci U S A. 2022 Apr 26;119(17):e2106083119. doi: 10.1073/pnas.2106083119. Epub 2022 Apr 21. PMID: 35446623
Autophagy and pluripotency: self-eating your way to eternal youth. Xu Y, Yang X. Trends Cell Biol. 2022 Apr 27:S0962-8924(22)00089-7. doi: 10.1016/j.tcb.2022.04.001. Online ahead of print. PMID: 35490141

March 2022

Signaling Through FcγRIIA and the C5a-C5aR Pathway Mediate Platelet Hyperactivation in COVID-19. Apostolidis SA, Sarkar A, Giannini HM, Goel RR, Mathew D, Suzuki A, Baxter AE, Greenplate AR, Alanio C, Abdel-Hakeem M, Oldridge DA, Giles JR, Wu JE, Chen Z, Huang YJ, Belman J, Pattekar A, Manne S, Kuthuru O, Dougherty J, Weiderhold B, Weisman AR, Ittner CAG, Gouma S, Dunbar D, Frank I, Huang AC, Vella LA; UPenn COVID Processing Unit, Reilly JP, Hensley SE, Rauova L, Zhao L, Meyer NJ, Poncz M, Abrams CS, Wherry EJ. Front Immunol. 2022 Mar 3;13:834988. doi: 10.3389/fimmu.2022.834988. eCollection 2022. PMID: 35309299
Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers. Giles JR, Manne S, Freilich E, Oldridge DA, Baxter AE, George S, Chen Z, Huang H, Chilukuri L, Carberry M, Giles L, Weng NP, Young RM, June CH, Schuchter LM, Amaravadi RK, Xu X, Karakousis GC, Mitchell TC, Huang AC, Shi J, Wherry EJ. Immunity. 2022 Mar 8;55(3):557-574.e7. doi: 10.1016/j.immuni.2022.02.004. PMID: 35263570
Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals. Lederer K, Bettini E, Parvathaneni K, Painter MM, Agarwal D, Lundgreen KA, Weirick M, Muralidharan K, Castaño D, Goel RR, Xu X, Drapeau EM, Gouma S, Ort JT, Awofolaju M, Greenplate AR, Le Coz C, Romberg N, Trofe-Clark J, Malat G, Jones L, Rosen M, Weiskopf D, Sette A, Besharatian B, Kaminiski M, Hensley SE, Bates P, Wherry EJ, Naji A, Bhoj V, Locci M. Cell. 2022 Mar 17;185(6):1008-1024.e15. doi: 10.1016/j.cell.2022.01.027. Epub 2022 Feb 2. PMID: 35202565
Examining the Impact of Galectin-9 on Latent HIV Transcription. Adeniji OS, Giron LB, Abdel-Mohsen M. Methods Mol Biol. 2022;2442:463-474. doi: 10.1007/978-1-0716-2055-7_25. PMID: 35320541
Trends and Outcomes of Hypothermic Machine Perfusion Preservation of Kidney Allografts in Simultaneous Liver and Kidney Transplantation in the United States . Chang A, Schaubel DE, Chen M, Abt PL, Bittermann T. Transpl Int. 2022 Mar 14;35:10345. doi: 10.3389/ti.2022.10345. eCollection 2022. PMID: 35356400
Incidence of acute rejection and patient survival in combined heart-liver transplantation . Zhao K, Wang R, Kamoun M, Callans L, Bremner R, Rame E, McLean R, Cevasco M, Olthoff KM, Levine MH, Shaked A, Abt PL.Liver Transpl. 2022 Mar 5. doi: 10.1002/lt.26448. Online ahead of print.PMID: 35247292
Antibodies to Crucial Epitopes on HSV-2 Glycoprotein D as a Guide to Dosing an mRNA Genital Herpes Vaccine . Hook LM, Awasthi S, Cairns TM, Alameh MG, Fowler BT, Egan KP, Sung MMH, Weissman D, Cohen GH, Friedman HM. Viruses. 2022 Mar 5;14(3):540. doi: 10.3390/v14030540. PMID: 35336946
Significance of RUNX1 mutation in BCR-ABL1 positive acute myeloid leukemia - a diagnostic dilemma in a young woman with persistent bleeding . Ghosh S, Roth J, Babushok D, Lim M. Leuk Lymphoma. 2022 Mar 15:1-5. doi: 10.1080/10428194.2022.2047673. Online ahead of print. PMID: 35290157
Venetoclax in combination with hypomethylating agents or low dose cytarabine for relapsed and refractory acute myeloid leukemia . Graveno ME, Carulli A, Freyer CW, Mangan BL, Nietupski R, Loren AW, Frey NV, Porter DL, Gill SI, Hexner EO, Luger SM, Martin ME, McCurdy SR, Perl AE, Babushok DV, Pratz KW. Leuk Lymphoma. 2022 Mar 8:1-6. doi: 10.1080/10428194.2022.2042688. Online ahead of print. PMID: 35259056
Progressive retinal changes in pediatric multiple sclerosis . Longoni G, Brown RA, Oyefiade A, Iruthayanathan R, Wilbur C, Shams S, Noguera A, Grover SA, O'Mahony J, Chung L, Wan MJ, Mah JK, Costello F, Arnold DL, Marrie RA, Bar-Or A, Banwell B, Mabbott D, Reginald AY, Yeh EA. Mult Scler Relat Disord. 2022 Mar 23;61:103761. doi: 10.1016/j.msard.2022.103761. Online ahead of print. PMID: 35349885
Stability of the gut microbiota in persons with paediatric-onset multiple sclerosis and related demyelinating diseases . Liang G, Zhu F, Mirza AI, Bar-Or A, Bernstein CN, Bonner C, Forbes JD, Graham M, Hart J, Knox NC, Marrie RA, O'Mahony J, Van Domselaar G, Yeh EA, Zhao Y, Banwell B, Waubant E, Tremlett H; Canadian Paediatric Demyelinating Disease Network. Mult Scler. 2022 Mar 16:13524585221079533. doi: 10.1177/13524585221079533. Online ahead of print. PMID: 35296164
Efficacy and safety of ofatumumab in recently diagnosed, treatment-naive patients with multiple sclerosis: Results from ASCLEPIOS I and II. Gärtner J, Hauser SL, Bar-Or A, Montalban X, Cohen JA, Cross AH, Deiva K, Ganjgahi H, Häring DA, Li B, Pingili R, Ramanathan K, Su W, Willi R, Kieseier B, Kappos L. Mult Scler. 2022 Mar 10:13524585221078825. doi: 10.1177/13524585221078825. Online ahead of print. PMID: 35266417
Effect of siponimod on magnetic resonance imaging measures of neurodegeneration and myelination in secondary progressive multiple sclerosis: Gray matter atrophy and magnetization transfer ratio analyses from the EXPAND phase 3 trial . Arnold DL, Piani-Meier D, Bar-Or A, Benedict RH, Cree BA, Giovannoni G, Gold R, Vermersch P, Arnould S, Dahlke F, Hach T, Ritter S, Karlsson G, Kappos L, Fox RJ; EXPAND Clinical Investigators. Mult Scler. 2022 Mar 9:13524585221076717. doi: 10.1177/13524585221076717. Online ahead of print. PMID: 35261318
Pathways to cures for multiple sclerosis: A research roadmap . Bebo BF Jr, Allegretta M, Landsman D, Zackowski KM, Brabazon F, Kostich WA, Coetzee T, Ng AV, Marrie RA, Monk KR, Bar-Or A, Whitacre CC. Mult Scler. 2022 Mar;28(3):331-345. doi: 10.1177/13524585221075990. PMID: 35236198
Accumulation of meningeal lymphocytes correlates with white matter lesion activity in progressive multiple sclerosis . Ahmed SM, Fransen NL, Touil H, Michailidou I, Huitinga I, Gommerman JL, Bar-Or A, Ramaglia V. JCI Insight. 2022 Mar 8;7(5):e151683. doi: 10.1172/jci.insight.151683. PMID: 35104246
Treatment of a genetic brain disease by CNS-wide microglia replacement . Shibuya Y, Kumar KK, Mader MM, Yoo Y, Ayala LA, Zhou M, Mohr MA, Neumayer G, Kumar I, Yamamoto R, Marcoux P, Liou B, Bennett FC, Nakauchi H, Sun Y, Chen X, Heppner FL, Wyss-Coray T, Südhof TC, Wernig M. Sci Transl Med. 2022 Mar 16;14(636):eabl9945. doi: 10.1126/scitranslmed.abl9945. Epub 2022 Mar 16. PMID: 35294256
Innate lymphoid cells and COVID-19 severity in SARS-CoV-2 infection . Silverstein NJ, Wang Y, Manickas-Hill Z, Carbone C, Dauphin A, Boribong BP, Loiselle M, Davis J, Leonard MM, Kuri-Cervantes L; MGH COVID-19 Collection & Processing Team, Meyer NJ, Betts MR, Li JZ, Walker BD, Yu XG, Yonker LM, Luban J. Elife. 2022 Mar 11;11:e74681. doi: 10.7554/eLife.74681. PMID: 35275061
Prednisolone reduces the interferon response to AAV in cynomolgus macaques and may increase liver gene expression . Wang L, Warzecha CC, Kistner A, Chichester JA, Bell P, Buza EL, He Z, Pampena MB, Couthouis J, Sethi S, McKeever K, Betts MR, Kakkis E, Wilson JM, Wadsworth S, Sullivan BA. Mol Ther Methods Clin Dev. 2022 Jan 19;24:292-305. doi: 10.1016/j.omtm.2022.01.007. eCollection 2022 Mar 10. PMID: 35211641
Variables affecting outcomes after allogeneic hematopoietic stem cell transplant for cerebral adrenoleukodystrophy . Chiesa R, Boelens JJ, Duncan CN, Kühl JS, Sevin C, Kapoor N, Prasad VK, Lindemans CA, Jones SA, Amartino HM, Algeri M, Bunin N, Diaz-de-Heredia C, Loes DJ, Shamir E, Timm A, McNeil E, Dietz AC, Orchard PJ. Blood Adv. 2022 Mar 8;6(5):1512-1524. doi: 10.1182/bloodadvances.2021005294. PMID: 34781360
Dual Affinity to RBCs and Target Cells (DART) Enhances Both Organ- and Cell Type-Targeting of Intravascular Nanocarriers . Ferguson LT, Hood ED, Shuvaeva T, Shuvaev VV, Basil MC, Wang Z, Nong J, Ma X, Wu J, Myerson JW, Marcos-Contreras OA, Katzen J, Carl JM, Morrisey EE, Cantu E, Villa CH, Mitragotri S, Muzykantov VR, Brenner JS. ACS Nano. 2022 Mar 22;16(3):4666-4683. doi: 10.1021/acsnano.1c11374. Epub 2022 Mar 10. PMID: 35266686
On the Twentieth Anniversary of Dendritic Cell Vaccines - Riding the Next Wave . Linette GP, Carreno BM. Cancer Res. 2022 Mar 15;82(6):966-968. doi: 10.1158/0008-5472.CAN-21-4440. PMID: 35288731
Impact of diagnostic genetics on remission MRD and transplantation outcomes in older AML patients. Murdock HM, Kim HT, Denlinger N, Vachhani P, Hambley BC, Manning BS, Gier S, Cho C, Tsai HK, McCurdy SR, Ho VT, Koreth J, Soiffer RJ, Ritz J, Carroll MP, Vasu S, Perales MA, Wang ES, Gondek LP, Devine SM, Alyea EP, Lindsley RC, Gibson CJ. Blood. 2022 Mar 14:blood.2021014520. doi: 10.1182/blood.2021014520. Online ahead of print. PMID: 35286378
BCOR and BCORL1 Mutations Drive Epigenetic Reprogramming and Oncogenic Signaling by Unlinking PRC1.1 from Target Genes . Schaefer EJ, Wang HC, Karp HQ, Meyer CA, Cejas P, Gearhart MD, Adelman ER, Fares I, Apffel A, Lim K, Xie Y, Gibson CJ, Schenone M, Murdock HM, Wang ES, Gondek LP, Carroll MP, Vedula RS, Winer ES, Garcia JS, Stone RM, Luskin MR, Carr SA, Long HW, Bardwell VJ, Figueroa ME, Lindsley RC. Blood Cancer Discov. 2022 Mar 1;3(2):116-135. doi: 10.1158/2643-3230.BCD-21-0115. PMID: 35015684
Early Plasma Nuclear DNA, Mitochondrial DNA, and Nucleosome Concentrations Are Associated With Acute Kidney Injury in Critically Ill Trauma Patients . Faust HE, Oniyide O, Wang Y, Forker CM, Dunn T, Yang W, Lanken PN, Sims CA, Yehya N, Christie JD, Meyer NJ, Reilly JP, Mangalmurti NS, Shashaty MGS. Crit Care Explor. 2022 Mar 28;4(4):e0663. doi: 10.1097/CCE.0000000000000663. eCollection 2022 Apr. PMID: 35372847
SARS-CoV-2 vaccination and ITP in patients with de novo or preexisting ITP. Lee EJ, Beltrami-Moreira M, Al-Samkari H, Cuker A, DiRaimo J, Gernsheimer T, Kruse A, Kessler C, Kruse C, Leavitt AD, Lee AI, Liebman HA, Newland AC, Ray AE, Tarantino MD, Thachil J, Kuter DJ, Cines DB, Bussel JB. Blood. 2022 Mar 10;139(10):1564-1574. doi: 10.1182/blood.2021013411. PMID: 34587251
Antibodies to Crucial Epitopes on HSV-2 Glycoprotein D as a Guide to Dosing an mRNA Genital Herpes Vaccine. Hook LM, Awasthi S, Cairns TM, Alameh MG, Fowler BT, Egan KP, Sung MMH, Weissman D, Cohen GH, Friedman HM. Viruses. 2022 Mar 5;14(3):540. doi: 10.3390/v14030540. PMID: 35336946
A Summary of the Sixth International Workshop on Microbiome in HIV Pathogenesis, Prevention, and Treatment . Sherrill-Mix S, Yang M, Aldrovandi GM, Brenchley JM, Bushman FD, Collman RG, Dandekar S, Klatt NR, Lagenaur LA, Landay AL, Paredes R, Tachedjian G, Turpin JA, Serrano-Villar S, Lozupone CA, Ghosh M. AIDS Res Hum Retroviruses. 2022 Mar;38(3):173-180. doi: 10.1089/AID.2021.0173. Epub 2022 Jan 25. PMID: 34969255
The Pathogenesis and Long-Term Consequences of COVID-19 Cardiac Injury . Siripanthong B, Asatryan B, Hanff TC, Chatha SR, Khanji MY, Ricci F, Muser D, Ferrari VA, Nazarian S, Santangeli P, Deo R, Cooper LT Jr, Mohiddin SA, Chahal CAA. JACC Basic Transl Sci. 2022 Mar;7(3):294-308. doi: 10.1016/j.jacbts.2021.10.011. Epub 2022 Feb 9. PMID: 35165665
Risk Prediction Models for Atherosclerotic Cardiovascular Disease in Patients with Chronic Kidney Disease: The CRIC Study . Bundy JD, Rahman M, Matsushita K, Jaeger BC, Cohen JB, Chen J, Deo R, Dobre MA, Feldman HI, Flack J, Kallem RR, Lash JP, Seliger S, Shafi T, Weiner SJ, Wolf M, Yang W, Allen NB, Bansal N, He J; CRIC Study Investigators. J Am Soc Nephrol. 2022 Mar;33(3):601-611. doi: 10.1681/ASN.2021060747. Epub 2022 Feb 10. PMID: 35145041
Suppressing or Enhancing Macrophage Engulfment through the Use of CD47 and Related Peptides . Jalil AR, Tobin MP, Discher DE. Bioconjug Chem. 2022 Mar 22. doi: 10.1021/acs.bioconjchem.2c00019. Online ahead of print. PMID: 35316023
Human CD47-Derived Cyclic Peptides Enhance Engulfment of mAb-Targeted Melanoma by Primary Macrophages . Jalil AR, Andrechak JC, Hayes BH, Chenoweth DM, Discher DE. Bioconjug Chem. 2022 Mar 14. doi: 10.1021/acs.bioconjchem.2c00020. Online ahead of print. PMID: 35285229
A One Medicine Mission for an Effective Rabies Therapy . Knobel DL, Jackson AC, Bingham J, Ertl HCJ, Gibson AD, Hughes D, Joubert K, Mani RS, Mohr BJ, Moore SM, Rivett-Carnac H, Tordo N, Yeates JW, Zambelli AB, Rupprecht CE. Front Vet Sci. 2022 Mar 16;9:867382. doi: 10.3389/fvets.2022.867382. eCollection 2022. PMID: 35372555
Immunological Biomarker Discovery in Cure Regimens for Chronic Hepatitis B Virus Infection . Gehring AJ, Mendez P, Richter K, Ertl H, Donaldson EF, Mishra P, Maini M, Boonstra A, Lauer G, de Creus A, Whitaker K, Martinez SF, Weber J, Gainor E, Miller V. J Hepatol. 2022 Mar 5:S0168-8278(22)00127-1. doi: 10.1016/j.jhep.2022.02.020. Online ahead of print. PMID: 35259469
The effect of rapamycin and ibrutinib on antibody responses to adeno-associated virus vector-mediated gene transfer . Xiang Z, Kuranda K, Quinn W, Chekaoui A, Ambrose R, Hasanpourghadi M, Novikov M, Newman D, Cole C, Zhou X, Mingozzi F, Ertl HCJ. Hum Gene Ther. 2022 Mar 1. doi: 10.1089/hum.2021.258. Online ahead of print. PMID: 35229644
A prospective, multicenter study of bortezomib, cyclophosphamide, and dexamethasone in relapsed/refractory iMCD . Zhang L, Zhang MY, Cao XX, Zhou DB, Fajgenbaum DC, Dong YJ, Li J. Leuk Lymphoma. 2022 Mar;63(3):618-626. doi: 10.1080/10428194.2021.1999437. Epub 2022 Jan 31. PMID: 35100929
Rio de Janeiro Global Consensus on Landmarks, Definitions and Classifications in Barrett's Esophagus: World Endoscopy Organization Delphi Study . Emura F, Chandrasekar VT, Hassan C, Armstrong D, Messmann H, Arantes V, Araya R, Barrera-Leon O, Bergman JJGHM, Bandhari P, Bourke MJ, Cerisoli C, Wai-Yan Chiu P, Desai M, Dinis-Ribeiro M, Falk GW, Fujishiro M, Gaddam S, Goda K, Gross S, Haidry R, Ho L, Iyer P, Kashin S, Kothari S, Lee YY, Matsuda K, Neuhaus H, Oyama T, Ragunath K, Repici A, Shaheen N, Singh R, Sobrino-Cossio S, Wang KK, Waxman I, Sharma P. Gastroenterology. 2022 Mar 23:S0016-5085(22)00284-0. doi: 10.1053/j.gastro.2022.03.022. Online ahead of print. PMID: 35339464
Prospective Endoscopic Activity Assessment for Eosinophilic Gastritis in a Multisite Cohort . Hirano I, Collins MH, King E, Sun Q, Chehade M, Abonia JP, Bonis PA, Capocelli KE, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Leung J, Katzka D, Menard-Katcher P, Khoury P, Klion A, Mukkada VA, Peterson K, Shoda T, Rudman-Spergel AK, Spergel JA, Yang GY, Rothenberg ME, Aceves SS, Furuta GT; CEGIR investigators. Am J Gastroenterol. 2022 Mar 1;117(3):413-423. doi: 10.14309/ajg.0000000000001625. PMID: 35080202
Analysis of Routine Computed Tomographic Scans With Radiomics and Machine Learning: One Step Closer to Clinical Practice . Farwell MD, Mankoff DA. JAMA Oncol. 2022 Mar 1;8(3):393-394. doi: 10.1001/jamaoncol.2021.6768. PMID: 35050318
NTRK-fusions in pediatric thyroid tumors: Current state and future perspectives . Casado-Medrano V, O'Neill A, Halada S, Laetsch TW, Bauer AJ, Franco AT. Cancer Genet. 2022 Mar 6;264-265:23-28. doi: 10.1016/j.cancergen.2022.02.009. Online ahead of print. PMID: 35290879
WWOX-Mediated Degradation of AMOTp130 Negatively Affects Egress of Filovirus VP40 Virus-Like Particles . Liang J, Ruthel G, Freedman BD, Harty RN. J Virol. 2022 Mar 23;96(6):e0202621. doi: 10.1128/jvi.02026-21. Epub 2022 Feb 2. PMID: 35107375
Schistosome TRPML channels play a role in neuromuscular activity and tegumental integrity . Bais S, Norwillo A, Ruthel G, Herbert DR, Freedman BD, Greenberg RM. Biochimie. 2022 Mar;194:108-117. doi: 10.1016/j.biochi.2021.12.018. Epub 2022 Jan 3. PMID: 34990770
Plasma Genotyping at the Time of Diagnostic Tissue Biopsy Decreases Time-to-Treatment in Patients With Advanced NSCLC-Results From a Prospective Pilot Study . Thompson JC, Aggarwal C, Wong J, Nimgaonkar V, Hwang WT, Andronov M, Dibardino DM, Hutchinson CT, Ma KC, Lanfranco A, Moon E, Haas AR, Singh AP, Ciunci CA, Marmarelis M, D'Avella C, Cohen JV, Bauml JM, Cohen RB, Langer CJ, Vachani A, Carpenter EL. JTO Clin Res Rep. 2022 Mar 8;3(4):100301. doi: 10.1016/j.jtocrr.2022.100301. eCollection 2022 Apr. PMID: 35392653
Detection of the HIV-1 Accessory Proteins Nef and Vpu by Flow Cytometry Represents a New Tool to Study Their Functional Interplay within a Single Infected CD4⁺ T Cell . Prévost J, Richard J, Gasser R, Medjahed H, Kirchhoff F, Hahn BH, Kappes JC, Ochsenbauer C, Duerr R, Finzi A. J Virol. 2022 Mar 23;96(6):e0192921. doi: 10.1128/jvi.01929-21. Epub 2022 Jan 26. PMID: 35080425
Developmental endothelial locus-1 protects from hypertension-induced cardiovascular remodeling via immunomodulation . Failer T, Amponsah-Offeh M, Neuwirth A, Kourtzelis I, Subramanian P, Mirtschink P, Peitzsch M, Matschke K, Tugtekin SM, Kajikawa T, Li X, Steglich A, Gembardt F, Wegner AC, Hugo C, Hajishengallis G, Chavakis T, Deussen A, Todorov V, Kopaliani I. J Clin Invest. 2022 Mar 15;132(6):e126155. doi: 10.1172/JCI126155. PMID: 35133978
Supporting Careers of Women in Clinical Immunology: From Conceptualization to Implementation . Dimitriades VR, Freeman AF, Henrickson SE, Abraham RS. Front Pediatr. 2022 Mar 29;10:864734. doi: 10.3389/fped.2022.864734. eCollection 2022. PMID: 35425731
Too much and not enough: tuning human primary T cell cytokine signaling networks. Henrickson SE. Sci Immunol. 2022 Mar 4;7(69):eabo7677. doi: 10.1126/sciimmunol.abo7677. Epub 2022 Mar 4. PMID: 35245087
Potent suppression of neuroendocrine tumors and gastrointestinal cancers by CDH17CAR T cells without toxicity to normal tissues. Feng Z, He X, Zhang X, Wu Y, Xing B, Knowles A, Shan Q, Miller S, Hojnacki T, Ma J, Katona BW, Gade TPF, Schrader J, Metz DC, June CH, Hua X. Nat Cancer. 2022 Mar 21. doi: 10.1038/s43018-022-00344-7. Online ahead of print. PMID: 35314826
2-Aminothiophene derivatives as a new class of positive allosteric modulators of glucagon-like peptide 1 receptor . Redij T, McKee JA, Do P, Campbell JA, Ma J, Li Z, Miller N, Srikanlaya C, Zhang D, Hua X, Li Z. Chem Biol Drug Des. 2022 Mar 21. doi: 10.1111/cbdd.14039. Online ahead of print. PMID: 35313084
Anti-CD19 CAR T Cells in Combination with Ibrutinib for the Treatment of Chronic Lymphocytic Leukemia . Gill SI, Frey NV, Hexner E, Metzger S, O'Brien M, Hwang WT, Brogdon JL, Davis MM, Fraietta JA, Gaymon A, Gladney WL, Lacey SF, Lamontagne A, Mato AR, Maus MV, Melenhorst JJ, Pequignot E, Ruella M, Shestov MA, Byrd JC, Schuster SJ, Siegel DL, Levine BL, June CH, Porter DL. Blood Adv. 2022 Mar 29:bloodadvances.2022007317. doi: 10.1182/bloodadvances.2022007317. Online ahead of print. PMID: 35349631
Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers . Giles JR, Manne S, Freilich E, Oldridge DA, Baxter AE, George S, Chen Z, Huang H, Chilukuri L, Carberry M, Giles L, Weng NP, Young RM, June CH, Schuchter LM, Amaravadi RK, Xu X, Karakousis GC, Mitchell TC, Huang AC, Shi J, Wherry EJ. Immunity. 2022 Mar 8;55(3):557-574.e7. doi: 10.1016/j.immuni.2022.02.004. PMID: 35263570
Developmental venous anomalies are a genetic primer for cerebral cavernous malformations. Snellings DA, Girard R, Lightle R, Srinath A, Romanos S, Li Y, Chen C, Ren AA, Kahn ML, Awad IA, Marchuk DA. Nat Cardiovasc Res. 2022 Mar;1:246-252. doi: 10.1038/s44161-022-00035-7. Epub 2022 Mar 14. PMID: 35355835
Lung lymphatic thrombosis and dysfunction caused by cigarette smoke exposure precedes emphysema in mice . Summers BD, Kim K, Clement CC, Khan Z, Thangaswamy S, McCright J, Maisel K, Zamora S, Quintero S, Racanelli AC, Redmond D, D'Armiento J, Yang J, Kuang A, Monticelli L, Kahn ML, Choi AMK, Santambrogio L, Reed HO. Sci Rep. 2022 Mar 23;12(1):5012. doi: 10.1038/s41598-022-08617-y. PMID: 35322079
Endothelial MEKK3-KLF2/4 signaling integrates inflammatory and hemodynamic signals during definitive hematopoiesis. Yang Y, Mumau M, Tober J, Zhu Q, Bennett L, Hong C, Sung DC, Keller TCS, Uzun Y, Gao P, Shewale S, Chen M, Yang J, Chen X, Thomas SA, Tan K, Speck NA, Kahn ML. Blood. 2022 Mar 4:blood.2021013934. doi: 10.1182/blood.2021013934. Online ahead of print. PMID: 35245372
HLA antigens to epitopes: Meeting the challenge . Norin AJ, Gebel HM, Kamoun M. Hum Immunol. 2022 Mar;83(3):270-271. doi: 10.1016/j.humimm.2022.01.015. Epub 2022 Feb 8. PMID: 35148924
Accurate long-term prediction of death for patients with cirrhosis . Goldberg D, Mantero A, Kaplan D, Delgado C, John B, Nuchovich N, Emanuel E, Reese PP. Hepatology. 2022 Mar 12. doi: 10.1002/hep.32457. Online ahead of print. PMID: 35278226
Plasma-Soluble Biomarkers for Fibrodysplasia Ossificans Progressiva (FOP) Reflect Acute and Chronic Inflammatory States. Pignolo RJ, McCarrick-Walmsley R, Wang H, Qiu S, Hunter J, Barr S, He K, Zhang H, Kaplan FS. J Bone Miner Res. 2022 Mar;37(3):475-483. doi: 10.1002/jbmr.4492. Epub 2022 Jan 24. PMID: 34954853
Correction to: The PROVe Study: US Real-World Experience with Chlormethine/Mechlorethamine Gel in Combination with Other Therapies for Patients with Mycosis Fungoides Cutaneous T-Cell Lymphoma . Kim EJ, Guitart J, Querfeld C, Girardi M, Musiek A, Akilov OE, Angello JT, Bailey WL, Geskin LJ. Am J Clin Dermatol. 2022 Mar 15. doi: 10.1007/s40257-022-00676-1. Online ahead of print. PMID: 35292936
Usage and safety of topical tacrolimus in patients with mycosis fungoides . Weiner DM, Clark AK, Bhansali RS, Pappas-Taffer L, Barta SK, Villasenor-Park J, Haun PL, Vittorio CC, Rook AH, Kim EJ, Samimi SS. Clin Exp Dermatol. 2022 Mar 4. doi: 10.1111/ced.15162. Online ahead of print. PMID: 35245947
The Base-Editing Enzyme APOBEC3A Catalyzes Cytosine Deamination in RNA with Low Proficiency and High Selectivity . Barka A, Berríos KN, Bailer P, Schutsky EK, Wang T, Kohli RM. ACS Chem Biol. 2022 Mar 18;17(3):629-636. doi: 10.1021/acschembio.1c00919. Epub 2022 Mar 9. PMID: 35262324
Mutant IDH Inhibits IFNγ-TET2 Signaling to Promote Immunoevasion and Tumor Maintenance in Cholangiocarcinoma . Wu MJ, Shi L, Dubrot J, Merritt J, Vijay V, Wei TY, Kessler E, Olander KE, Adil R, Pankaj A, Tummala KS, Weeresekara V, Zhen Y, Wu Q, Luo M, Shen W, García-Beccaria M, Fernández-Vaquero M, Hudson C, Ronseaux S, Sun Y, Saad-Berreta R, Jenkins RW, Wang T, Heikenwälder M, Ferrone CR, Goyal L, Nicolay B, Deshpande V, Kohli RM, Zheng H, Manguso RT, Bardeesy N. Cancer Discov. 2022 Mar 1;12(3):812-835. doi: 10.1158/2159-8290.CD-21-1077. PMID: 34848557
Antibiotics and ECMO in the Adult Population-Persistent Challenges and Practical Guides. Gomez F, Veita J, Laudanski K. Antibiotics (Basel). 2022 Mar 4;11(3):338. doi: 10.3390/antibiotics11030338. PMID: 35326801
HiCuT: An efficient and low input method to identify protein-directed chromatin interactions . Sati S, Jones P, Kim HS, Zhou LA, Rapp-Reyes E, Leung TH. PLoS Genet. 2022 Mar 23;18(3):e1010121. doi: 10.1371/journal.pgen.1010121. eCollection 2022 Mar. PMID: 35320278
Neutrophilic Dermatoses: a Clinical Update . Weiss EH, Ko CJ, Leung TH, Micheletti RG, Mostaghimi A, Ramachandran SM, Rosenbach M, Nelson CA. Curr Dermatol Rep. 2022 Mar 16:1-14. doi: 10.1007/s13671-022-00355-8. Online ahead of print. PMID: 35310367
The Use and Duration of Preintubation Respiratory Support Is Associated With Increased Mortality in Immunocompromised Children With Acute Respiratory Failure . Lindell RB, Fitzgerald JC, Rowan CM, Flori HR, Di Nardo M, Napolitano N, Traynor DM, Lenz KB, Emeriaud G, Jeyapalan A, Nishisaki A; National Emergency Airway Registry for Children (NEAR4KIDS) and Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Crit Care Med. 2022 Mar 14. doi: 10.1097/CCM.0000000000005535. Online ahead of print. PMID: 35275593
BAMM (BRAF Autophagy and MEK Inhibition in Melanoma): A Phase I/II Trial of Dabrafenib, Trametinib, and Hydroxychloroquine in Advanced BRAFV600-mutant Melanoma . Mehnert JM, Mitchell TC, Huang AC, Aleman TS, Kim BJ, Schuchter LM, Linette GP, Karakousis GC, Mitnick S, Giles L, Carberry M, Frey N, Kossenkov A, Groisberg R, Hernandez-Aya LF, Ansstas G, Silk AW, Chandra S, Sosman JA, Gimotty PA, Mick R, Amaravadi RK. Clin Cancer Res. 2022 Mar 15;28(6):1098-1106. doi: 10.1158/1078-0432.CCR-21-3382. PMID: 35022320
No increase in inflammation in late-life major depression screened to exclude physical illness . Luning Prak ET, Brooks T, Makhoul W, Beer JC, Zhao L, Girelli T, Skarke C, Sheline YI. Transl Psychiatry. 2022 Mar 24;12(1):118. doi: 10.1038/s41398-022-01883-4. PMID: 35332134
Modulation of CD22 Protein Expression in Childhood Leukemia by Pervasive Splicing Aberrations: Implications for CD22-Directed Immunotherapies . Zheng S, Gillespie E, Naqvi AS, Hayer KE, Ang Z, Torres-Diz M, Quesnel-Vallières M, Hottman DA, Bagashev A, Chukinas J, Schmidt C, Asnani M, Shraim R, Taylor DM, Rheingold SR, O'Brien MM, Singh N, Lynch KW, Ruella M, Barash Y, Tasian SK, Thomas-Tikhonenko A. Blood Cancer Discov. 2022 Mar 1;3(2):103-115. doi: 10.1158/2643-3230.BCD-21-0087. PMID: 35015683
State-dependent olfactory processing in freely behaving mice . Schreck MR, Zhuang L, Janke E, Moberly AH, Bhattarai JP, Gottfried JA, Wesson DW, Ma M. Cell Rep. 2022 Mar 1;38(9):110450. doi: 10.1016/j.celrep.2022.110450. PMID: 35235805
Glutamate in primary afferents is required for itch transmission . Cui L, Guo J, Cranfill SL, Gautam M, Bhattarai J, Olson W, Beattie K, Challis RC, Wu Q, Song X, Raabe T, Gradinaru V, Ma M, Liu Q, Luo W. Neuron. 2022 Mar 2;110(5):809-823.e5. doi: 10.1016/j.neuron.2021.12.007. Epub 2022 Jan 4. PMID: 34986325
Trefoil Factor Family: A Troika for Lung Repair and Regeneration. Rossi HL, Ortiz-Carpena JF, Tucker D, Vaughan AE, Mangalmurti NS, Cohen NA, Herbert DR. Am J Respir Cell Mol Biol. 2022 Mar;66(3):252-259. doi: 10.1165/rcmb.2021-0373TR. PMID: 34784491
Do CARs finally hit the CLL road? Kater AP, Melenhorst JJ. Blood. 2022 Mar 24;139(12):1775-1776. doi: 10.1182/blood.2021014492. PMID: 35323881
STAT3 Role in T-Cell Memory Formation . Kaminskiy Y, Melenhorst JJ. Int J Mol Sci. 2022 Mar 7;23(5):2878. doi: 10.3390/ijms23052878. PMID: 35270020
Response to: Correspondence on '2022 American College of Rheumatology/European Alliance of Associations for Rheumatology classification criteria for granulomatosis with polyangiitis' by Joanna C Robson et al and '2022 American College of Rheumatology/European Alliance of Associations for Rheumatology classification criteria for microscopic polyangiitis' by Ravi Suppiah et al. Grayson PC, Robson JC, Suppiah R, Ponte C, Watts RA, Luqmani RA, Merkel PA. Ann Rheum Dis. 2022 Mar 22:annrheumdis-2022-222362. doi: 10.1136/annrheumdis-2022-222362. Online ahead of print. PMID: 35318216
Psychometric properties of outcome measurement instruments for ANCA-associated vasculitis: a systematic literature review . Berti A, Boleto G, Merkel PA, Tómasson G, Monti S, Quinn KA, Hassett LC, Carmona L, Ramiro S; OMERACT Vasculitis Working Group. Rheumatology (Oxford). 2022 Mar 16:keac175. doi: 10.1093/rheumatology/keac175. Online ahead of print. PMID: 35293985
2022 American College of Rheumatology/European Alliance of Associations for Rheumatology Classification Criteria for Eosinophilic Granulomatosis with Polyangiitis. Grayson PC, Ponte C, Suppiah R, Robson JC, Craven A, Judge A, Khalid S, Hutchings A, Luqmani RA, Watts RA, Merkel PA; DCVAS Study Group. Ann Rheum Dis. 2022 Mar;81(3):309-314. doi: 10.1136/annrheumdis-2021-221794. Epub 2022 Feb 2. PMID: 35110334
Pulmonary and Critical Care Considerations for E-Cigarette, or Vaping, Product Use-Associated Lung Injury . Hayes D Jr, Board A, Calfee C, Ellington S, Pollack LA, Kathuria H, Eakin MN, Weissman DN, Callahan SJ, Esper AM, Crotty Alexander LE, Sharma NS, Meyer NJ, Smith LS, Novosad S, Evans ME, Goodman AB, Click ES, Robinson RT, Ewart G, Twentyman E. Chest. 2022 Mar 5:S0012-3692(22)00406-8. doi: 10.1016/j.chest.2022.02.039. Online ahead of print. PMID: 35257738
ONP-302 Nanoparticles Inhibit Tumor Growth By Altering Tumor-Associated Macrophages And Cancer-Associated Fibroblasts . Donthireddy L, Vonteddu P, Murthy T, Kwak T, Eraslan RN, Podojil JR, Elhofy A, Boyne MT 2nd, Puisis JJ, Veglia F, Singh SS, Dotiwala F, Montaner LJ, Gabrilovich DI. J Cancer. 2022 Mar 28;13(6):1933-1944. doi: 10.7150/jca.69338. eCollection 2022. PMID: 35399717
"We are looking at the future right now": community acceptability of a home-based viral load test device in the context of HIV cure-related research with analytical treatment interruptions in the United States. Dubé K, Kanazawa J, Roebuck C, Johnson S, Carter WB, Dee L, Peterson B, Lynn KM, Lalley-Chareczko L, Hiserodt E, Kim S, Rosenbloom D, Evans BR, Anderson M, Hazuda DJ, Shipley L, Bateman K, Howell BJ, Mounzer K, Tebas P, Montaner LJ. HIV Res Clin Pract. 2022 Mar 29:1-16. Online ahead of print. PMID: 35348047
Single-cell multiomics reveals persistence of HIV-1 in expanded cytotoxic T cell clones . Collora JA, Liu R, Pinto-Santini D, Ravindra N, Ganoza C, Lama JR, Alfaro R, Chiarella J, Spudich S, Mounzer K, Tebas P, Montaner LJ, van Dijk D, Duerr A, Ho YC. Immunity. 2022 Mar 17:S1074-7613(22)00127-3. doi: 10.1016/j.immuni.2022.03.004. Online ahead of print. PMID: 35320704
Reproductive Technology Considerations in Uterus Transplant . Walter JR, O'Neill KE. Clin Obstet Gynecol. 2022 Mar 1;65(1):68-75. doi: 10.1097/GRF.0000000000000684. PMID: 35045027
mRNA-encoded HIV-1 Env trimer ferritin nanoparticles induce monoclonal antibodies that neutralize heterologous HIV-1 isolates in mice . Mu Z, Wiehe K, Saunders KO, Henderson R, Cain DW, Parks R, Martik D, Mansouri K, Edwards RJ, Newman A, Lu X, Xia SM, Eaton A, Bonsignori M, Montefiori D, Han Q, Venkatayogi S, Evangelous T, Wang Y, Rountree W, Korber B, Wagh K, Tam Y, Barbosa C, Alam SM, Williams WB, Tian M, Alt FW, Pardi N, Weissman D, Haynes BF. Cell Rep. 2022 Mar 15;38(11):110514. doi: 10.1016/j.celrep.2022.110514. PMID: 35294883
Pemphigus and Pemphigoid: From Disease Mechanisms to Druggable Pathways . Ellebrecht CT, Maseda D, Payne AS. J Invest Dermatol. 2022 Mar;142(3 Pt B):907-914. doi: 10.1016/j.jid.2021.04.040. Epub 2021 Oct 29. PMID: 34756581
Preliminary Evaluation of ⁶⁸Ga-P16-093, a PET Radiotracer Targeting Prostate-Specific Membrane Antigen in Prostate Cancer . Lee H, Scheuermann JS, Young AJ, Doot RK, Daube-Witherspoon ME, Schubert EK, Fillare MA, Alexoff D, Karp JS, Kung HF, Pryma DA. Mol Imaging Biol. 2022 Mar 29. doi: 10.1007/s11307-022-01720-6. Online ahead of print. PMID: 35349040
Associations of abdominal and cardiovascular adipose tissue depots with HDL metrics in midlife women: The SWAN Study . Nasr A, Matthews K, Janssen I, Brooks MM, Barinas-Mitchell E, Orchard TJ, Billheimer J, Wang NC, McConnell D, Rader DJ, El Khoudary SR. J Clin Endocrinol Metab. 2022 Mar 17:dgac148. doi: 10.1210/clinem/dgac148. Online ahead of print. PMID: 35298649
Dietary Vitamin E intake is associated with a reduced risk of developing digestive diseases and NAFLD . Scorletti E, Creasy KT, Vujkovic M, Vell M, Zandvakili I, Rader DJ, Schneider KM, Schneider CV. Am J Gastroenterol. 2022 Mar 14. doi: 10.14309/ajg.0000000000001726. Online ahead of print. PMID: 35288522
The relationship between lipoproteins and insulin sensitivity in youth with obesity and abnormal glucose tolerance. Chung ST, Katz LEL, Stettler-Davis N, Shults J, Sherman A, Ha J, Stefanovski D, Boston RC, Rader DJ, Magge SN. J Clin Endocrinol Metab. 2022 Mar 3:dgac113. doi: 10.1210/clinem/dgac113. Online ahead of print. PMID: 35240684
Sortilin restricts secretion of apolipoprotein B-100 by hepatocytes under stressed but not basal conditions. Conlon DM, Schneider CV, Ko YA, Rodrigues A, Guo K, Hand NJ, Rader DJ. J Clin Invest. 2022 Mar 15;132(6):e144334. doi: 10.1172/JCI144334. PMID: 35113816
A systematic review of the natural history and biomarkers of primary lecithin:cholesterol acyltransferase deficiency . Vitali C, Bajaj A, Nguyen C, Schnall J, Chen J, Stylianou K, Rader DJ, Cuchel M. J Lipid Res. 2022 Mar;63(3):100169. doi: 10.1016/j.jlr.2022.100169. Epub 2022 Jan 20. PMID: 35065092
Association of Telomere Length With Risk of Disease and Mortality. Schneider CV, Schneider KM, Teumer A, Rudolph KL, Hartmann D, Rader DJ, Strnad P. .JAMA Intern Med. 2022 Mar 1;182(3):291-300. doi: 10.1001/jamainternmed.2021.7804. PMID: 35040871
Early prediction of decompensation (EPOD) score: Non-invasive determination of cirrhosis decompensation risk. Schneider ARP, Schneider CV, Schneider KM, Baier V, Schaper S, Diedrich C, Coboeken K, Mayer H, Gu W, Trebicka J, Blank LM, Burghaus R, Lippert J, Rader DJ, Thaiss CA, Schlender JF, Trautwein C, Kuepfer L. Liver Int. 2022 Mar;42(3):640-650. doi: 10.1111/liv.15161. Epub 2022 Feb 3. PMID: 35007409
A novel role for endoplasmic reticulum protein 46 (ERp46) in platelet function and arterial thrombosis in mice. Zhou J, Wu Y, Rauova L, Koma G, Wang L, Poncz M, Li H, Liu T, Fong KP, Bennett JS, Kunapuli SP, Essex DW. Blood. 2022 Mar 31;139(13):2050-2065. doi: 10.1182/blood.2021012055. PMID: 34752599
Modulation of CD22 Protein Expression in Childhood Leukemia by Pervasive Splicing Aberrations: Implications for CD22-Directed Immunotherapies. Zheng S, Gillespie E, Naqvi AS, Hayer KE, Ang Z, Torres-Diz M, Quesnel-Vallières M, Hottman DA, Bagashev A, Chukinas J, Schmidt C, Asnani M, Shraim R, Taylor DM, Rheingold SR, O'Brien MM, Singh N, Lynch KW, Ruella M, Barash Y, Tasian SK, Thomas-Tikhonenko A. Blood Cancer Discov. 2022 Mar 1;3(2):103-115. doi: 10.1158/2643-3230.BCD-21-0087. PMID: 35015683
Erosive hand osteoarthritis: latest findings and outlook . Favero M, Belluzzi E, Ortolan A, Lorenzin M, Oliviero F, Doria A, Scanzello CR, Ramonda R. Nat Rev Rheumatol. 2022 Mar;18(3):171-183. doi: 10.1038/s41584-021-00747-3. Epub 2022 Feb 1. PMID: 35105980
Differentiating children with sepsis with and without acute respiratory distress syndrome using proteomics. Yehya N, Fazelinia H, Taylor DM, Lawrence GG, Spruce LA, Thompson JM, Margulies SS, Seeholzer SH, Worthen GS. Am J Physiol Lung Cell Mol Physiol. 2022 Mar 1;322(3):L365-L372. doi: 10.1152/ajplung.00164.2021. Epub 2022 Jan 5. PMID: 34984927
Bleach baths for atopic dermatitis: A systematic review and meta-analysis including unpublished data, Bayesian interpretation, and GRADE. Bakaa L, Pernica JM, Couban RJ, Tackett KJ, Burkhart CN, Leins L, Smart J, Garcia-Romero MT, Elizalde-Jiménez IG, Herd M, Asiniwasis RN, Boguniewicz M, De Benedetto A, Chen L, Ellison K, Frazier W, Greenhawt M, Huynh J, LeBovidge J, Lind ML, Lio P, O'Brien M, Ong PY, Silverberg JI, Spergel JM, Wang J, Begolka WS, Schneider L, Chu DK. Ann Allergy Asthma Immunol. 2022 Mar 30:S1081-1206(22)00286-1. doi: 10.1016/j.anai.2022.03.024. Online ahead of print. PMID: 35367346
Annals editors on the war in Ukraine. Grayson MH, Borish L, Castells MC, Greenhawt MJ, Leung DYM, Lieberman JA, Marshall GD, Nowak-Wegrzyn A, Oppenheimer J, Shaker MS, Shulenberger K, Spergel J, Stukus DR. Ann Allergy Asthma Immunol. 2022 Mar 24:S1081-1206(22)00209-5. doi: 10.1016/j.anai.2022.03.018. Online ahead of print. PMID: 35342018
Development of Food Allergy Data Dictionary: Toward a Food Allergy Data Commons. Sehgal S, Gupta RS, Wlodarski M, Bilaver LA, Wehbe FH, Spergel JM, Wang J, Ciaccio CE, Makhija M, Starren JB. J Allergy Clin Immunol Pract. 2022 Mar 5:S2213-2198(22)00225-2. doi: 10.1016/j.jaip.2022.02.024. Online ahead of print. PMID: 35259539
Adverse events and labeling issues related to suspected sesame allergy reported in an online survey. Nguyen K, Greenthal E, Sorscher S, Lurie P, Spergel JM, Kennedy K. Ann Allergy Asthma Immunol. 2022 Mar;128(3):279-282. doi: 10.1016/j.anai.2021.12.005. Epub 2021 Dec 7. PMID: 34883240
Bcl-xL enforces a slow-cycling state necessary for survival in the nutrient-deprived microenvironment of pancreatic cancer. Sela Y, Li J, Maheswaran S, Norgard RJ, Yuan S, Hubbi ME, Doepner M, Xu JP, Ho ES, Mesaros C, Sheehan C, Croley G, Muir A, Blair IA, Shalem O, Dang CV, Stanger BZ. Cancer Res. 2022 Mar 22:canres.CAN-22-0431-E.2022. doi: 10.1158/0008-5472.CAN-22-0431. Online ahead of print. PMID: 35315913
KAT6A and ENL Form an Epigenetic Transcriptional Control Module to Drive Critical Leukemogenic Gene-Expression Programs. Yan F, Li J, Milosevic J, Petroni R, Liu S, Shi Z, Yuan S, Reynaga JM, Qi Y, Rico J, Yu S, Liu Y, Rokudai S, Palmisiano N, Meyer SE, Sung PJ, Wan L, Lan F, Garcia BA, Stanger BZ, Sykes DB, Blanco MA. Cancer Discov. 2022 Mar 1;12(3):792-811. doi: 10.1158/2159-8290.CD-20-1459. PMID: 34853079
The role of mTORC1 activation in seizure-induced exacerbation of Alzheimer's disease. Gourmaud S, Stewart DA, Irwin DJ, Roberts N, Barbour AJ, Eberwine G, O'Brien WT, Vassar R, Talos DM, Jensen FE. Brain. 2022 Mar 29;145(1):324-339. doi: 10.1093/brain/awab268. PMID: 34264340
Children's Oncology Group Trial AALL1231: A Phase III Clinical Trial Testing Bortezomib in Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia and Lymphoma. Teachey DT, Devidas M, Wood BL, Chen Z, Hayashi RJ, Hermiston ML, Annett RD, Archer JH, Asselin BL, August KJ, Cho SY, Dunsmore KP, Fisher BT, Freedman JL, Galardy PJ, Harker-Murray P, Horton TM, Jaju AI, Lam A, Messinger YH, Miles RR, Okada M, Patel SI, Schafer ES, Schechter T, Singh N, Steele AC, Sulis ML, Vargas SL, Winter SS, Wood C, Zweidler-McKay P, Bollard CM, Loh ML, Hunger SP, Raetz EA. J Clin Oncol. 2022 Mar 10:JCO2102678. doi: 10.1200/JCO.21.02678. Online ahead of print. PMID: 35271306
Modulation of CD22 Protein Expression in Childhood Leukemia by Pervasive Splicing Aberrations: Implications for CD22-Directed Immunotherapies. Zheng S, Gillespie E, Naqvi AS, Hayer KE, Ang Z, Torres-Diz M, Quesnel-Vallières M, Hottman DA, Bagashev A, Chukinas J, Schmidt C, Asnani M, Shraim R, Taylor DM, Rheingold SR, O'Brien MM, Singh N, Lynch KW, Ruella M, Barash Y, Tasian SK, Thomas-Tikhonenko A. Blood Cancer Discov. 2022 Mar 1;3(2):103-115. doi: 10.1158/2643-3230.BCD-21-0087. PMID: 35015683
Stripenn detects architectural stripes from chromatin conformation data using computer vision. Yoon S, Chandra A, Vahedi G. Nat Commun. 2022 Mar 24;13(1):1602. doi: 10.1038/s41467-022-29258-9. PMID: 35332165
Trefoil Factor Family: A Troika for Lung Repair and Regeneration. Rossi HL, Ortiz-Carpena JF, Tucker D, Vaughan AE, Mangalmurti NS, Cohen NA, Herbert DR. Am J Respir Cell Mol Biol. 2022 Mar;66(3):252-259. doi: 10.1165/rcmb.2021-0373TR. PMID: 34784491
The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity. Zhang D, Atochina-Vasserman EN, Lu J, Maurya DS, Xiao Q, Liu M, Adamson J, Ona N, Reagan EK, Ni H, Weissman D, Percec V. J Am Chem Soc. 2022 Mar 23;144(11):4746-4753. doi: 10.1021/jacs.2c00273. Epub 2022 Mar 9. PMID: 35263098
Phase 2 Trial of Iberdomide in Systemic Lupus Erythematosus. Merrill JT, Werth VP, Furie R, van Vollenhoven R, Dörner T, Petronijevic M, Velasco J, Majdan M, Irazoque-Palazuelos F, Weiswasser M, Korish S, Ye Y, Gaudy A, Schafer PH, Liu Z, Agafonova N, Delev N. N Engl J Med. 2022 Mar 17;386(11):1034-1045. doi: 10.1056/NEJMoa2106535. PMID: 35294813
Correction to: Cannabinoid type 2 receptor (CB2R) distribution in dermatomyositis skin and peripheral blood mononuclear cells (PBMCs) and in vivo efects of Lenabasum^TM. Maddukuri S, Patel J, Diaz A, Chen KL, Wysocka M, Bax C, Li Y, Ravishankar A, Grinnell M, Zeidi M, Reddy N, Concha JSS, Bashir MM, Okawa J, White B, Werth VP. Arthritis Res Ther. 2022 Mar 11;24(1):69. doi: 10.1186/s13075-022-02758-1. PMID: 35277198
Mycophenolate Mofetil and Methotrexate Efficacy in Dermatomyositis. Grinnell M, Keyes E, Diaz D, Vazquez T, Feng R, Werth VP. Br J Dermatol. 2022 Mar 8. doi: 10.1111/bjd.21235. Online ahead of print. PMID: 35257367
T cell exhaustion and residency dynamics inform clinical outcomes in hepatocellular carcinoma. Barsch M, Salié H, Schlaak AE, Zhang Z, Hess M, Mayer LS, Tauber C, Otto-Mora P, Ohtani T, Nilsson T, Wischer L, Winkler F, Manne S, Rech A, Schmitt-Graeff A, Bronsert P, Hofmann M, Neumann-Haefelin C, Boettler T, Fichtner-Feigl S, van Boemmel F, Berg T, Rimassa L, Di Tommaso L, Saeed A, D'Alessio A, Pinato DJ, Bettinger D, Binder H, Wherry EJ, Schultheiss M, Thimme R, Bengsch B. J Hepatol. 2022 Mar 31:S0168-8278(22)00180-5. doi: 10.1016/j.jhep.2022.02.032. Online ahead of print. PMID: 35367533
Multi-ethnic Investigation of Risk and Immune Determinants of COVID-19 Outcomes. Jun T, Mathew D, Sharma N, Nirenberg S, Huang HH, Kovatch P, Wherry EJ, Huang KL. Res Sq. 2022 Mar 22:rs.3.rs-1055587. doi: 10.21203/rs.3.rs-1055587/v1. Preprint. PMID: 35350196
Understanding T-cell responses to COVID-19 is essential for informing public health strategies. Vardhana S, Baldo L, Morice WG 2nd, Wherry EJ. Sci Immunol. 2022 Mar 24:eabo1303. doi: 10.1126/sciimmunol.abo1303. Online ahead of print. PMID: 35324269
Inhibiting the β1integrin subunit increases the strain threshold for neuronal dysfunction under tensile loading in collagen gels mimicking innervated ligaments . Singh S, Winkelstein BA. Biomech Model Mechanobiol. 2022 Mar 12. doi: 10.1007/s10237-022-01565-6. Online ahead of print. PMID: 35279768
The Macronutrient Composition of Infant Formula Produces Differences in Gut Microbiota Maturation That Associate with Weight Gain Velocity and Weight Status. Mennella JA, Li Y, Bittinger K, Friedman ES, Zhao C, Li H, Wu GD, Trabulsi JC. Nutrients. 2022 Mar 15;14(6):1241. doi: 10.3390/nu14061241. PMID: 35334900
Iron deficiency linked to altered bile acid metabolism promotes Helicobacter pylori-induced inflammation-driven gastric carcinogenesis . Noto JM, Piazuelo MB, Shah SC, Romero-Gallo J, Hart JL, Di C, Carmichael JD, Delgado AG, Halvorson AE, Greevy RA Jr, Wroblewski LE, Sharma A, Newton AB, Allaman MM, Wilson KT, Washington MK, Calcutt MW, Schey KL, Cummings BP, Flynn CR, Zackular JP, Peek RM Jr. J Clin Invest. 2022 Mar 22:e147822. doi: 10.1172/JCI147822. Online ahead of print. PMID: 35316215

February 2022

Batf-mediated epigenetic control of effector CD8 + T cell differentiation. Tsao HW, Kaminski J, Kurachi M, Barnitz RA, DiIorio MA, LaFleur MW, Ise W, Kurosaki T, Wherry EJ, Haining WN, Yosef N. Sci Immunol. 2022 Feb 18;7(68):eabi4919. doi: 10.1126/sciimmunol.abi4919. Epub 2022 Feb 18. PMID: 35179948
Cytomegalovirus latent infection is associated with an increased risk of COVID-19-related hospitalization. Alanio C, Verma A, Mathew D, Gouma S, Liang G, Dunn T, Oldridge DA, Weaver JE, Kuri-Cervantes L, Pampena MB; UPenn COVID Processing Unit, Betts MR, Collman RG, Bushman FD, Meyer NJ, Hensley SE, Rader D, Wherry EJ. J Infect Dis. 2022 Feb 2:jiac020. doi: 10.1093/infdis/jiac020. Online ahead of print. PMID: 35134186
Decade-long leukaemia remissions with persistence of CD4 + CAR T cells. Melenhorst JJ, Chen GM, Wang M, Porter DL, Chen C, Collins MA, Gao P, Bandyopadhyay S, Sun H, Zhao Z, Lundh S, Pruteanu-Malinici I, Nobles CL, Maji S, Frey NV, Gill SI, Tian L, Kulikovskaya I, Gupta M, Ambrose DE, Davis MM, Fraietta JA, Brogdon JL, Young RM, Chew A, Levine BL, Siegel DL, Alanio C, Wherry EJ, Bushman FD, Lacey SF, Tan K, June CH. Nature. 2022 Feb;602(7897):503-509. doi: 10.1038/s41586-021-04390-6. Epub 2022 Feb 2. PMID: 35110735
Development of Droplet Digital PCR-Based Assays to Quantify HIV Proviral and Integrated DNA in Brain Tissues from Viremic Individuals with Encephalitis and Virally Suppressed Aviremic Individuals. Chung HK, Hattler JB, Narola J, Babbar H, Cai Y, Abdel-Mohsen M, Kim WK. Microbiol Spectr. 2022 Feb 23;10(1):e0085321. doi: 10.1128/spectrum.00853-21. Epub 2022 Jan 12. PMID: 35019681
Thromboelastography profiles for controlled circulatory death donors: Validating the role of heparin. Crannell WC, Sally M, McConnell K, Connelly C, Maynard E, Dewey E, Abt P, Enestvedt CK. Clin Transplant. 2022 Feb;36(2):e14518. doi: 10.1111/ctr.14518. Epub 2021 Nov 29. PMID: 34668240
Clinical Applications of Somatostatin Receptor (Agonist) PET Tracers beyond Neuroendocrine Tumors. Helgebostad R, Revheim ME, Johnsrud K, Amlie K, Alavi A, Connelly JP. Diagnostics (Basel). 2022 Feb 18;12(2):528. doi: 10.3390/diagnostics12020528. PMID: 35204618
Advantages and Applications of Total-Body PET Scanning. Katal S, Eibschutz LS, Saboury B, Gholamrezanezhad A, Alavi A. Diagnostics (Basel). 2022 Feb 7;12(2):426. doi: 10.3390/diagnostics12020426. PMID: 35204517
Letermovir vs. high-dose valacyclovir for cytomegalovirus prophylaxis following haploidentical or mismatched unrelated donor allogeneic hematopoietic cell transplantation receiving post-transplant cyclophosphamide. Freyer CW, Carulli A, Gier S, Ganetsky A, Timlin C, Schuster M, Babushok D, Frey NV, Gill SI, Hexner EO, Luger SM, Mangan JK, Martin ME, McCurdy SR, Perl AE, Porter DL, Pratz K, Smith J, Stadtmauer EA, Loren AW. Leuk Lymphoma. 2022 Feb 20:1-9. doi: 10.1080/10428194.2022.2042686. Online ahead of print. PMID: 35188052
Vaccine Response in Patients With Multiple Sclerosis Receiving Teriflunomide. Tornatore C, Wiendl H, Lublin AL, Geertsen SS, Chavin J, Truffinet P, Bar-Or A. Front Neurol. 2022 Feb 28;13:828616. doi: 10.3389/fneur.2022.828616. eCollection 2022. PMID: 35295832 PMCID: PMC8918991
The health-related quality of life of children with multiple sclerosis is mediated by the health-related quality of life of their parents. O'Mahony J, Banwell B, Laporte A, Brown A, Bolongaita L, Bar-Or A, Yeh EA, Marrie RA. Mult Scler. 2022 Feb 7:13524585211061521. doi: 10.1177/13524585211061521. Online ahead of print. PMID: 35130081
Worsening physical functioning in patients with neuroinflammatory disease during the COVID-19 pandemic. Levit E, Cohen I, Dahl M, Edwards K, Weinstock-Guttman B, Ishikawa T, Kavak K, Leavitt V, Nelson K, Onomichi K, Bar-Or A, Perrone C, Riley C, Venkatesh S, De Jager PL, Xia Z, Longbrake EE; Multiple Sclerosis Resilience to COVID-19 (MSReCOV) Collaborative. Mult Scler Relat Disord. 2022 Feb;58:103482. doi: 10.1016/j.msard.2021.103482. Epub 2022 Jan 4. PMID: 35016114
Lymphocytes Utilize Somatic Mutations, Epigenetic Silencing, and the Proteasome to Escape Truncated WASP Expression. Khanna C, Le Coz C, Vaccaro C, Pillarisetti P, Knox AVC, Sy A, Behrens EM, Buchbinder D, Romberg N. J Clin Immunol. 2022 Feb 12. doi: 10.1007/s10875-022-01224-6. Online ahead of print. PMID: 35149963
Single-cell multi-omics analysis of human pancreatic islets reveals novel cellular states in type 1 diabetes. Fasolino M, Schwartz GW, Patil AR, Mongia A, Golson ML, Wang YJ, Morgan A, Liu C, Schug J, Liu J, Wu M, Traum D, Kondo A, May CL, Goldman N, Wang W, Feldman M, Moore JH, Japp AS, Betts MR; HPAP Consortium, Faryabi RB, Naji A, Kaestner KH, Vahedi G. Nat Metab. 2022 Feb;4(2):284-299. doi: 10.1038/s42255-022-00531-x. Epub 2022 Feb 28. PMID: 35228745
Unrelated donor α/β T cell- and B cell-depleted HSCT for the treatment of pediatric acute leukemia. Leahy AB, Li Y, Talano JA, Elgarten CW, Seif AE, Wang Y, Johnson B, Monos DS, Kadauke S, Olson TS, Freedman J, Wray L, Grupp SA, Bunin N. Blood Adv. 2022 Feb 22;6(4):1175-1185. doi: 10.1182/bloodadvances.2021005492. PMID: 34872106
Cost Utility of Lifelong Immunoglobulin Replacement Therapy vs Hematopoietic Stem Cell Transplant to Treat Agammaglobulinemia. Sun D, Heimall JR, Greenhawt MJ, Bunin NJ, Shaker MS, Romberg N. JAMA Pediatr. 2022 Feb 1;176(2):176-184. doi: 10.1001/jamapediatrics.2021.4583. PMID: 34779842
Genetic and phenotypic characteristics of Clostridium (Clostridioides) difficile from canine, bovine, and pediatric populations. Redding LE, Tu V, Abbas A, Alvarez M, Zackular JP, Gu C, Bushman FD, Kelly DJ, Barnhart D, Lee JJ, Bittinger KL. Anaerobe. 2022 Feb 23:102539. doi: 10.1016/j.anaerobe.2022.102539. Online ahead of print. PMID: 35217150
SARS-CoV-2 Delta Variant (AY.3) in the Feces of a Domestic Cat. Lenz OC, Marques AD, Kelly BJ, Rodino KG, Cole SD, Perera RAPM, Weiss SR, Bushman FD, Lennon EM. Viruses. 2022 Feb 17;14(2):421. doi: 10.3390/v14020421. PMID: 35216014
Rapid manufacturing of non-activated potent CAR T cells. Ghassemi S, Durgin JS, Nunez-Cruz S, Patel J, Leferovich J, Pinzone M, Shen F, Cummins KD, Plesa G, Cantu VA, Reddy S, Bushman FD, Gill SI, O'Doherty U, O'Connor RS, Milone MC. Nat Biomed Eng. 2022 Feb;6(2):118-128. doi: 10.1038/s41551-021-00842-6. Epub 2022 Feb 21. PMID: 35190680
Detection and Interspecies Comparison of SARS-CoV-2 Delta Variant (AY.3) in Feces from a Domestic Cat and Human Samples. Lenz OC, Marques AD, Kelly BJ, Rodino KG, Cole SD, Perera RAPM, Weiss SR, Bushman FD, Lennon EM. bioRxiv. 2022 Feb 2:2022.01.31.478506. doi: 10.1101/2022.01.31.478506. Preprint. PMID: 35132417
SARS-CoV-2 Variants Associated with Vaccine Breakthrough in the Delaware Valley through Summer 2021. Marques AD, Sherrill-Mix S, Everett JK, Reddy S, Hokama P, Roche AM, Hwang Y, Glascock A, Whiteside SA, Graham-Wooten J, Khatib LA, Fitzgerald AS, Moustafa AM, Bianco C, Rajagopal S, Helton J, Deming R, Denu L, Ahmed A, Kitt E, Coffin SE, Newbern C, Mell JC, Planet PJ, Badjatia N, Richards B, Wang ZX, Cannuscio CC, Strelau KM, Jaskowiak-Barr A, Cressman L, Loughrey S, Ganguly A, Feldman MD, Collman RG, Rodino KG, Kelly BJ, Bushman FD. mBio. 2022 Feb 8;13(1):e0378821. doi: 10.1128/mbio.03788-21. Online ahead of print. PMID: 35130727
Sepsis with liver dysfunction and coagulopathy predicts an inflammatory pattern of macrophage activation . Anderko RR, Gómez H, Canna SW, Shakoory B, Angus DC, Yealy DM, Huang DT, Kellum JA, Carcillo JA; ProCESS Investigators. Intensive Care Med Exp. 2022 Feb 21;10(1):6. doi: 10.1186/s40635-022-00433-y. PMID: 35190900
Serum proteome analysis of systemic JIA and related lung disease identifies distinct inflammatory programs and biomarkers. Chen G, Deutsch GH, Schulert G, Zheng H, Jang S, Trapnell B, Lee P, Macaubas C, Ho K, Schneider C, Saper VE, de Jesus AA, Krasnow M, Grom A, Goldbach-Mansky R, Khatri P, Mellins ED, Canna SW. Arthritis Rheumatol. 2022 Feb 21. doi: 10.1002/art.42099. Online ahead of print. PMID: 35189047
NEMO-NDAS: A Panniculitis in the Young Representing an Autoinflammatory Disorder in Disguise. Hegazy S, Marques MC, Canna SW, Goldbach-Mansky R, de Jesus AA, Reyes-Múgica M, Salgado CM. Am J Dermatopathol. 2022 Feb 2. doi: 10.1097/DAD.0000000000002144. Online ahead of print. PMID: 35120036
Forging Forward in Photodynamic Therapy . Cramer GM, Cengel KA, Busch TM. Cancer Res. 2022 Feb 15;82(4):534-536. doi: 10.1158/0008-5472.CAN-21-4122. PMID: 35180305
Multi-Trait Genome-Wide Association Study of Atherosclerosis Detects Novel Pleiotropic Loci. Bellomo TR, Bone WP, Chen BY, Gawronski KAB, Zhang D, Park J, Levin M, Tsao N, Klarin D, Lynch J, Assimes TL, Gaziano JM, Wilson PW, Cho K, Vujkovic M, O'Donnell CJ, Chang KM, Tsao PS, Rader DJ, Ritchie MD, Damrauer SM, Voight BF. Front Genet. 2022 Feb 2;12:787545. doi: 10.3389/fgene.2021.787545. eCollection 2021. PMID: 35186008
Subcellular Detection of SARS-CoV-2 RNA in Human Tissue Reveals Distinct Localization in Alveolar Type 2 Pneumocytes and Alveolar Macrophages. Acheampong KK, Schaff DL, Emert BL, Lake J, Reffsin S, Shea EK, Comar CE, Litzky LA, Khurram NA, Linn RL, Feldman M, Weiss SR, Montone KT, Cherry S, Shaffer SM. mBio. 2022 Feb 8;13(1):e0375121. doi: 10.1128/mbio.03751-21. Online ahead of print. PMID: 35130722
NF-κB perturbation reveals unique immunomodulatory functions in Prx1⁺fibroblasts that promote development of atopic dermatitis. Ko KI, Merlet JJ, DerGarabedian BP, Zhen H, Suzuki-Horiuchi Y, Hedberg ML, Hu E, Nguyen AT, Prouty S, Alawi F, Walsh MC, Choi Y, Millar SE, Cliff A, Romero J, Garvin MR, Seykora JT, Jacobson D, Graves DT .Sci Transl Med. 2022 Feb 2;14(630):eabj0324. doi: 10.1126/scitranslmed.abj0324. Epub 2022 Feb 2. PMID: 35108061
Divergent impacts of tocilizumab and colchicine in COVID-19-associated coagulopathy: the role of alpha-defensins. Abdeen S, Abu-Fanne R, Bdeir K, Maraga E, Higazi M, Cines DB, Heyman SN, Higazi AA. Br J Haematol. 2022 Feb;196(4):923-927. doi: 10.1111/bjh.17885. Epub 2021 Oct 27. PMID: 34622440
SARS-CoV-2 Variants Associated with Vaccine Breakthrough in the Delaware Valley through Summer 2021. Marques AD, Sherrill-Mix S, Everett JK, Reddy S, Hokama P, Roche AM, Hwang Y, Glascock A, Whiteside SA, Graham-Wooten J, Khatib LA, Fitzgerald AS, Moustafa AM, Bianco C, Rajagopal S, Helton J, Deming R, Denu L, Ahmed A, Kitt E, Coffin SE, Newbern C, Mell JC, Planet PJ, Badjatia N, Richards B, Wang ZX, Cannuscio CC, Strelau KM, Jaskowiak-Barr A, Cressman L, Loughrey S, Ganguly A, Feldman MD, Collman RG, Rodino KG, Kelly BJ, Bushman FD. mBio. 2022 Feb 8;13(1):e0378821. doi: 10.1128/mbio.03788-21. Online ahead of print. PMID: 35130727
Synthetic Antibiotic Derived from Sequences Encrypted in a Protein from Human Plasma. Cesaro A, Torres MDT, Gaglione R, Dell'Olmo E, Di Girolamo R, Bosso A, Pizzo E, Haagsman HP, Veldhuizen EJA, de la Fuente-Nunez C, Arciello A. ACS Nano. 2022 Feb 22;16(2):1880-1895. doi: 10.1021/acsnano.1c04496. Epub 2022 Feb 3. PMID: 35112568
External Beam Radiation Therapy for Primary Liver Cancers: An ASTRO Clinical Practice Guideline. Apisarnthanarax S, Barry A, Cao M, Czito B, DeMatteo R, Drinane M, Hallemeier CL, Koay EJ, Lasley F, Meyer J, Owen D, Pursley J, Schaub SK, Smith G, Venepalli NK, Zibari G, Cardenes H. Pract Radiat Oncol. 2022 Jan-Feb;12(1):28-51. doi: 10.1016/j.prro.2021.09.004. Epub 2021 Oct 21. PMID: 34688956
Prediction of Incident Heart Failure in CKD: The CRIC Study. Zelnick LR, Shlipak MG, Soliman EZ, Anderson A, Christenson R, Kansal M, Deo R, He J, Jaar BG, Weir MR, Rao P, Cohen DL, Cohen JB, Feldman HI, Go A, Bansal N; CRIC Study Investigators Kidney Int Rep. 2022 Feb 2;7(4):708-719. doi: 10.1016/j.ekir.2022.01.1067. eCollection 2022 Apr. PMID: 35497796
Teaming up to return to play: A shared responsibility to optimize care . Chokshi NP, Deo R. Heart Rhythm O2. 2022 Feb 22;3(2):141-142. doi: 10.1016/j.hroo.2022.02.012. eCollection 2022 Apr. PMID: 35496456
Fluticasone Propionate Orally Disintegrating Tablet (APT-1011) for Eosinophilic Esophagitis: Randomized Controlled Trial. Dellon ES, Lucendo AJ, Schlag C, Schoepfer AM, Falk GW, Eagle G, Nezamis J, Comer GM, Knoop K, Hirano I. Clin Gastroenterol Hepatol. 2022 Feb 16:S1542-3565(22)00139-2. doi: 10.1016/j.cgh.2022.02.013. Online ahead of print. PMID: 35181572
Mast cell-pain connection in eosinophilic esophagitis . Zhang S, Shoda T, Aceves SS, Arva NC, Chehade M, Collins MH, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Khoury P, Leung J, Spergel AKR, Spergel JM, Wechsler JB, Yang GY, Furuta GT, Rothenberg ME; Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) Investigators Group. Allergy. 2022 Feb 17. doi: 10.1111/all.15260. Online ahead of print. PMID: 35175645
R eliability and responsiveness of endoscopic disease activity assessment in eosinophilic esophagitis. Ma C, Bredenoord AJ, Dellon ES, Alexander JA, Biedermann L, Hogan M, Guizzetti L, Zou G, Katzka DA, Chehade M, Falk GW, Furuta GT, Gupta SK, Kagalwalla AF, Schoepfer AM, Miehlke S, Moawad FJ, Peterson K, Gonsalves NP, Straumann A, Wechsler JB, Rémillard J, Shackelton LM, Almonte HS, Feagan BG, Jairath V, Hirano I. Gastrointest Endosc. 2022 Feb 1:S0016-5107(22)00082-7. doi: 10.1016/j.gie.2022.01.014. Online ahead of print. PMID: 35120883
Development and Validation of Web-Based Tool to Predict Lamina Propria Fibrosis in Eosinophilic Esophagitis. Hiremath G, Sun L, Correa H, Acra S, Collins MH, Bonis P, Arva NC, Capocelli KE, Falk GW, King E, Gonsalves N, Gupta SK, Hirano I, Mukkada VA, Martin LJ, Putnam PE, Spergel JM, Wechsler JB, Yang GY, Aceves SS, Furuta GT, Rothenberg ME, Koyama T, Dellon ES. Am J Gastroenterol. 2022 Feb 1;117(2):272-279. doi: 10.14309/ajg.0000000000001587. PMID: 34932022
LKB1 drives stasis and C/EBP-mediated reprogramming to an alveolar type II fate in lung cancer. Murray CW, Brady JJ, Han M, Cai H, Tsai MK, Pierce SE, Cheng R, Demeter J, Feldser DM, Jackson PK, Shackelford DB, Winslow MM. Nat Commun. 2022 Feb 28;13(1):1090. doi: 10.1038/s41467-022-28619-8. PMID: 35228570
A retrospective study of HIV pre-exposure prophylaxis counselling among non-Hispanic Black youth diagnosed with bacterial sexually transmitted infections in the United States, 2014-2019. Watson DL, Shaw PA, Petsis DT, Pickel J, Bauermeister JA, Frank I, Wood SM, Gross R. J Int AIDS Soc. 2022 Feb;25(2):e25867. doi: 10.1002/jia2.25867. PMID: 35192740
Sedation and Analgesia in Patients Undergoing Tracheostomy in COVID-19, a Multi-Center Registry. Kapp CM, Latifi A, Feller-Kopman D, Atkins JH, Ben Or E, Dibardino D, Haas AR, Thiboutot J, Hutchinson CT. J Intensive Care Med. 2022 Feb;37(2):240-247. doi: 10.1177/08850666211045896. Epub 2021 Oct 12. PMID: 34636705
Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine. Goel RR, Painter MM, Lundgreen KA, Apostolidis SA, Baxter AE, Giles JR, Mathew D, Pattekar A, Reynaldi A, Khoury DS, Gouma S, Hicks P, Dysinger S, Hicks A, Sharma H, Herring S, Korte S, Kc W, Oldridge DA, Erickson RI, Weirick ME, McAllister CM, Awofolaju M, Tanenbaum N, Dougherty J, Long S, D'Andrea K, Hamilton JT, McLaughlin M, Williams JC, Adamski S, Kuthuru O, Drapeau EM, Davenport MP, Hensley SE, Bates P, Greenplate AR, Wherry EJ. bioRxiv. 2022 Feb 22:2022.02.20.481163. doi: 10.1101/2022.02.20.481163. Preprint. PMID: 35233575
Immunogenetics of heteroclitic recognition of HLA-DQB1 55R eplet specificity by human alloantibody. Kamoun M, Askar M, Kearns JD, Bui TM, Nguyen M, Brown NK, Duquesnoy RJ. Hum Immunol. 2022 Feb;83(2):99-106. doi: 10.1016/j.humimm.2021.11.001. Epub 2021 Nov 20. PMID: 34815108
Patterns of germline and somatic testing after universal tumor screening for Lynch syndrome: A clinical practice survey of active members of the Collaborative Group of the Americas on Inherited Gastrointestinal Cancer. Hodan R, Rodgers-Fouche L, Arora S, Dominguez-Valentin M, Kanth P, Katona BW, Mraz KA, Roberts ME, Vilar E, Soto-Azghani CM, Brand RE, Esplin ED, Perez K. J Genet Couns. 2022 Feb 26. doi: 10.1002/jgc4.1567. Online ahead of print. PMID: 35218578
Upper Gastrointestinal Cancer Surveillance in Lynch Syndrome . Kumar S, Farha N, Burke CA, Katona BW. Cancers (Basel). 2022 Feb 16;14(4):1000. doi: 10.3390/cancers14041000. PMID: 35205747
Detection of Early-Stage Pancreatic Ductal Adenocarcinoma From Blood Samples: Results of a Multiplex Biomarker Signature Validation Study . Brand RE, Persson J, Bratlie SO, Chung DC, Katona BW, Carrato A, Castillo M, Earl J, Kokkola A, Lucas AL, Moser AJ, DeCicco C, Mellby LD, King TC.Clin Transl Gastroenterol. 2022 Feb 14;13(3):e00468. doi: 10.14309/ctg.0000000000000468. PMID: 35166713
Quo Vadis Anesthesiologist? The Value Proposition of Future Anesthesiologists Lies in Preserving or Restoring Presurgical Health after Surgical Insult. Laudanski K .J Clin Med. 2022 Feb 21;11(4):1135. doi: 10.3390/jcm11041135. PMID: 35207406
Cellular Memories - More Than Skin Deep. Leung TH, Cotsarelis G. N Engl J Med. 2022 Feb 24;386(8):793-795. doi: 10.1056/NEJMcibr2118516. PMID: 35196433
Blocking Kir6.2 channels with SpTx1 potentiates glucose-stimulated insulin secretion from murine pancreatic β cells and lowers blood glucose in diabetic mice . Ramu Y, Yamakaze J, Zhou Y, Hoshi T, Lu Z. Elife. 2022 Feb 25;11:e77026. doi: 10.7554/eLife.77026. PMID: 35212627
Publisher Correction: Ventral striatal islands of Calleja neurons control grooming in mice . Zhang YF, Vargas Cifuentes L, Wright KN, Bhattarai JP, Mohrhardt J, Fleck D, Janke E, Jiang C, Cranfill SL, Goldstein N, Schreck M, Moberly AH, Yu Y, Arenkiel BR, Betley JN, Luo W, Stegmaier J, Wesson DW, Spehr M, Fuccillo MV, Ma M. Nat Neurosci. 2022 Feb;25(2):264. doi: 10.1038/s41593-021-01003-3. PMID: 34992258
BET-bromodomain and EZH2 inhibitor treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes. Zaiken MC, Flynn R, Paz KG, Rhee SY, Jin S, Mohamed FA, Saha A, Thangavelu G, Park PMC, Hemming ML, Sage PT, Sharpe AH, DuPage M, Bluestone JA, Panoskaltsis-Mortari A, Cutler CS, Koreth J, Antin JH, Soiffer RJ, Ritz J, Luznik L, Maillard I, Hill GR, MacDonald KP, Munn DH, Serody JS, Murphy WJ, Kean LS, Zhang Y, Bradner JE, Qi J, Blazar BR. Blood. 2022 Feb 28:blood.2021014557. doi: 10.1182/blood.2021014557. Online ahead of print. PMID: 35226736
The effects of plasma exchange in patients with ANCA-associated vasculitis: an updated systematic review and meta-analysis. Walsh M, Collister D, Zeng L, Merkel PA, Pusey CD, Guyatt G, Au Peh C, Szpirt W, Ito-Hara T, Jayne DRW; Plasma exchange and glucocorticoid dosing for patients with ANCA-associated vasculitis BMJ Rapid Recommendations Group. BMJ. 2022 Feb 25;376:e064604. doi: 10.1136/bmj-2021-064604. PMID: 35217545
A cortactin CTTN coding SNP contributes to lung vascular permeability and inflammatory disease severity in African descent subjects. Belvitch P, Casanova N, Sun X, Camp SM, Sammani S, Brown ME, Mascarhenas J, Lynn H, Adyshev D, Siegler J, Desai A, Seyed-Saadat L, Rizzo A, Bime C, Shekhawat GS, Dravid VP, Reilly JP, Jones TK, Feng R, Letsiou E, Meyer NJ, Ellis N, Garcia JGN, Dudek SM. Transl Res. 2022 Feb 15:S1931-5244(22)00022-6. doi: 10.1016/j.trsl.2022.02.002. Online ahead of print. PMID: 35181549
Lighting the way to personalized mRNA immune cell therapies. Metzloff AE, Billingsley MM, Mitchell MJ. Sci Adv. 2022 Feb 25;8(8):eabo2423. doi: 10.1126/sciadv.abo2423. Epub 2022 Feb 23. PMID: 35196095
Preliminary Acceptability of a Home-Based Peripheral Blood Collection Device for Viral Load Testing in the Context of Analytical Treatment Interruptions in HIV Cure Trials: Results from a Nationwide Survey in the United States. Dubé K, Eskaf S, Hastie E, Agarwal H, Henley L, Roebuck C, Carter WB, Dee L, Taylor J, Mapp D, Campbell DM, Villa TJ, Peterson B, Lynn KM, Lalley-Chareczko L, Hiserodt E, Kim S, Rosenbloom D, Evans BR, Anderson M, Hazuda DJ, Shipley L, Bateman K, Howell BJ, Mounzer K, Tebas P, Montaner LJ. J Pers Med. 2022 Feb 7;12(2):231. doi: 10.3390/jpm12020231. PMID: 35207719
PTEN Loss and BRCA1 Promoter Hypermethylation Negatively Predict for Immunogenicity in BRCA-Deficient Ovarian Cancer. Kraya AA, Maxwell KN, Eiva MA, Wubbenhorst B, Pluta J, Feldman M, Nayak A, Powell DJ Jr, Domchek SM, Vonderheide RH, Nathanson KL. JCO Precis Oncol. 2022 Feb;6:e2100159. doi: 10.1200/PO.21.00159. PMID: 35201851
Lyophilization provides long-term stability for a lipid nanoparticle-formulated, nucleoside-modified mRNA vaccine. Muramatsu H, Lam K, Bajusz C, Laczkó D, Karikó K, Schreiner P, Martin A, Lutwyche P, Heyes J, Pardi N. Mol Ther. 2022 Feb 4;30(5):1941-51. doi: 10.1016/j.ymthe.2022.02.001. Online ahead of print. PMID: 35131437
Response to Letter to Editor re: "Combined Quantification of 18F-FDG and 68Ga-DOTATATE PET/CT for Prognosis in High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms". Lee H, Nakamoto R, Moore SE, Pantel AR, Eads JR, Aparici CM, Pryma DA. Acad Radiol. 2022 Feb 26:S1076-6332(22)00107-6. doi: 10.1016/j.acra.2022.02.001. Online ahead of print. PMID: 35227613
Managing a High-Specific-Activity Iobenguane Therapy Clinic: From Operations to Reimbursement. O'Brien SR, Pryma DA. J Nucl Med. 2022 Feb;63(2):196-198. doi: 10.2967/jnumed.121.262306. Epub 2021 Dec 2. PMID: 34857657
Loss of p19Arf promotes fibroblast survival during leucine deprivation. Roby KC, Lieberman A, Kim BJ, Rodríguez NZ, Posimo JM, Tsang T, Verginadis II, Puré E, Brady DC, Koumenis C, Ryeom S. Biol Open. 2022 Feb 15;11(2):bio058728. doi: 10.1242/bio.058728. Epub 2022 Feb 17. PMID: 34994382
Cost Utility of Lifelong Immunoglobulin Replacement Therapy vs Hematopoietic Stem Cell Transplant to Treat Agammaglobulinemia. Sun D, Heimall JR, Greenhawt MJ, Bunin NJ, Shaker MS, Romberg N .JAMA Pediatr. 2022 Feb 1;176(2):176-184. doi: 10.1001/jamapediatrics.2021.4583. PMID: 34779842
Epigenetic Regulation of Apoptosis in Cutaneous T-Cell Lymphoma: Implications for Therapy with Methotrexate, Jak Inhibitors, and Resveratrol. Nihal M, Wu J, Stonesifer CJ, Daniels J, Choi J, Geskin L, Rook AH, Wood GS. J Invest Dermatol. 2022 Feb;142(2):493-496.e7. doi: 10.1016/j.jid.2021.06.034. Epub 2021 Aug 3. PMID: 34358529
Orofacial Granulomatosis Treated With Combination of Intralesional Steroids and Hydroxychloroquine. Bindakhil MA, Stoopler ET, Alawai F, Sollecito TP. Compend Contin Educ Dent. 2022 Feb;43(2):e1-e4. PMID: 35148477
A Pernicious Cycle Affecting Premalignant Stem Cells. Speck NA. N Engl J Med. 2022 Feb 10;386(6):596-598. doi: 10.1056/NEJMcibr2117528. PMID: 35139279
Development and Validation of Web-Based Tool to Predict Lamina Propria Fibrosis in Eosinophilic Esophagitis . Hiremath G, Sun L, Correa H, Acra S, Collins MH, Bonis P, Arva NC, Capocelli KE, Falk GW, King E, Gonsalves N, Gupta SK, Hirano I, Mukkada VA, Martin LJ, Putnam PE, Spergel JM, Wechsler JB, Yang GY, Aceves SS, Furuta GT, Rothenberg ME, Koyama T, Dellon ES. Am J Gastroenterol. 2022 Feb 1;117(2):272-279. doi: 10.14309/ajg.0000000000001587. PMID: 34932022
Epigenetic state determines inflammatory sensing in neuroblastoma. Wolpaw AJ, Grossmann LD, Dessau JL, Dong MM, Aaron BJ, Brafford PA, Volgina D, Pascual-Pasto G, Rodriguez-Garcia A, Uzun Y, Arsenian-Henriksson M, Powell DJ Jr, Bosse KR, Kossenkov A, Tan K, Hogarty MD, Maris JM, Dang CV. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2102358119. doi: 10.1073/pnas.2102358119. PMID: 35121657
Preliminary Acceptability of a Home-Based Peripheral Blood Collection Device for Viral Load Testing in the Context of Analytical Treatment Interruptions in HIV Cure Trials: Results from a Nationwide Survey in the United States . Dubé K, Eskaf S, Hastie E, Agarwal H, Henley L, Roebuck C, Carter WB, Dee L, Taylor J, Mapp D, Campbell DM, Villa TJ, Peterson B, Lynn KM, Lalley-Chareczko L, Hiserodt E, Kim S, Rosenbloom D, Evans BR, Anderson M, Hazuda DJ, Shipley L, Bateman K, Howell BJ, Mounzer K, Tebas P, Montaner LJ. J Pers Med. 2022 Feb 7;12(2):231. doi: 10.3390/jpm12020231. PMID: 35207719
Aging disrupts circadian gene regulation and function in macrophages. Blacher E, Tsai C, Litichevskiy L, Shipony Z, Iweka CA, Schneider KM, Chuluun B, Heller HC, Menon V, Thaiss CA, Andreasson KI. Nat Immunol. 2022 Feb;23(2):229-236. doi: 10.1038/s41590-021-01083-0. Epub 2021 Dec 23. PMID: 34949832
Advances in integrative African genomics. Zhang C, Hansen MEB, Tishkoff SA. Trends Genet. 2022 Feb;38(2):152-168. doi: 10.1016/j.tig.2021.09.013. Epub 2021 Nov 2. PMID: 34740451
Systematic illumination of druggable genes in cancer genomes. Jiang J, Yuan J, Hu Z, Zhang Y, Zhang T, Xu M, Long M, Fan Y, Tanyi JL, Montone KT, Tavana O, Vonderheide RH, Chan HM, Hu X, Zhang L .Cell Rep. 2022 Feb 22;38(8):110400. doi: 10.1016/j.celrep.2022.110400 .PMID: 35196490
Bonded cumomer analysis of tumor metabolism based on ¹³ C magnetic resonance spectroscopy. Shestov AA, Nath K, Nelson DS, Wasik MA, Glickson JD. NMR Biomed. 2022 Feb 23:e4716. doi: 10.1002/nbm.4716. Online ahead of print. PMID: 35196744
Detection and Interspecies Comparison of SARS-CoV-2 Delta Variant (AY.3) in Feces from a Domestic Cat and Human Samples. Lenz OC, Marques AD, Kelly BJ, Rodino KG, Cole SD, Perera RAPM, Weiss SR, Bushman FD, Lennon EM. bioRxiv. 2022 Feb 2:2022.01.31.478506. doi: 10.1101/2022.01.31.478506. Preprint. PMID: 35132417
Breadth of SARS-CoV-2 Neutralization and Protection Induced by a Nanoparticle Vaccine . Li D, Martinez DR, Schäfer A, Chen H, Barr M, Sutherland LL, Lee E, Parks R, Mielke D, Edwards W, Newman A, Bock KW, Minai M, Nagata BM, Gagne M, Douek D, DeMarco CT, Denny TN, Oguin TH, Brown A, Rountree W, Wang Y, Mansouri K, Edwards RJ, Ferrari G, Sempowski GD, Eaton A, Tang J, Cain DW, Santra S, Pardi N, Weissman D, Tomai M, Fox C, Moore IN, Andersen H, Lewis MG, Golding H, Khurana S, Seder R, Baric RS, Montefiori DC, Saunders KO, Haynes BF. bioRxiv. 2022 Feb 14:2022.01.26.477915. doi: 10.1101/2022.01.26.477915. Preprint. PMID: 35118474
Schlafens Can Put Viruses to Sleep . Kim ET, Weitzman MD. Viruses. 2022 Feb 21;14(2):442. doi: 10.3390/v14020442. PMID: 35216035
Adenovirus prevents dsRNA formation by promoting efficient splicing of viral RNA. Price AM, Steinbock RT, Di C, Hayer KE, Li Y, Herrmann C, Parenti NA, Whelan JN, Weiss SR, Weitzman MD. Nucleic Acids Res. 2022 Feb 22;50(3):1201-1220. doi: 10.1093/nar/gkab896 .PMID: 34671803
Rho Kinase regulates neutrophil NET formation that is involved in UVB-induced skin inflammation. Li M, Lyu X, Liao J, Werth VP, Liu ML. Theranostics. 2022 Feb 7;12(5):2133-2149. doi: 10.7150/thno.66457. eCollection 2022. PMID: 35265203
Defining anti-synthetase syndrome: a systematic literature review. Zanframundo G, Faghihi-Kashani S, Scirè CA, Bonella F, Corte TJ, Doyle TJ, Fiorentino D, Gonzalez-Gay MA, Hudson M, Kuwana M, Lundberg IE, Mammen A, McHugh N, Miller FW, Monteccucco C, Oddis CV, Rojas-Serrano J, Schmidt J, Selva-O'Callaghan A, Werth VP, Sakellariou G, Aggarwal R, Cavagna L. Clin Exp Rheumatol. 2022 Feb;40(2):309-319. doi: 10.55563/clinexprheumatol/8xj0b9. Epub 2022 Feb 25. PMID: 35225224
Letter to the Editor Reply Regarding ACR White Paper on Antimalarials and Cardiac Toxicity: Suggested Amendments to Future Directions. Desmarais J, Rosenbaum JT, Costenbader KH, Ginzler EM, Fett N, Goodman S, O'Dell J, Pineau CA, Schmajuk G, Werth VP, Link MS, Kovacs R. Arthritis Rheumatol. 2022 Feb 25. doi: 10.1002/art.42102. Online ahead of print. PMID: 35212179
Iberdomide in patients with systemic lupus erythematosus: a randomised, double-blind, placebo-controlled, ascending-dose, phase 2a study . Furie RA, Hough DR, Gaudy A, Ye Y, Korish S, Delev N, Weiswasser M, Zhan X, Schafer PH, Werth VP. Lupus Sci Med. 2022 Feb;9(1):e000581. doi: 10.1136/lupus-2021-000581. PMID: 35169036
A Microbial Signature for Pediatric Perianal Crohn's Disease. Breton J, Tanes C, Tu V, Albenberg L, Rowley S, Devas N, Hwang R, Kachelries K, Wu GD, Baldassano RN, Bittinger K, Mattei P. J Crohns Colitis. 2022 Feb 25:jjac032. doi: 10.1093/ecco-jcc/jjac032. Online ahead of print. PMID: 35211723

Jan 2022

NFAT-dependent and -independent exhaustion circuits program maternal CD8 T cell hypofunction in pregnancy. Lewis EL, Xu R, Beltra JC, Ngiow SF, Cohen J, Telange R, Crane A, Sawinski D, Wherry EJ, Porrett PM. J Exp Med. 2022 Jan 3;219(1):e20201599. doi: 10.1084/jem.20201599. Epub 2021 Dec 9. PMID: 34882194 PMCID: PMC8666877
Lentiviral globin gene therapy with reduced-intensity conditioning in adults with β-thalassemia: a phase 1 trial. Boulad F, Maggio A, Wang X, Moi P, Acuto S, Kogel F, Takpradit C, Prockop S, Mansilla-Soto J, Cabriolu A, Odak A, Qu J, Thummar K, Du F, Shen L, Raso S, Barone R, Di Maggio R, Pitrolo L, Giambona A, Mingoia M, Everett JK, Hokama P, Roche AM, Cantu VA, Adhikari H, Reddy S, Bouhassira E, Mohandas N, Bushman FD, Rivière I, Sadelain M. Nat Med. 2022 Jan 3. doi: 10.1038/s41591-021-01554-9. Online ahead of print. PMID: 34980909
Potential and Most Relevant Applications of Total Body PET/CT Imaging. Alavi A, Saboury B, Nardo L, Zhang V, Wang M, Li H, Raynor WY, Werner TJ, Høilund-Carlsen PF, Revheim ME. Clin Nucl Med. 2022 Jan 1;47(1):43-55. doi: 10.1097/RLU.0000000000003962. PMID: 34874348
Artificial Intelligence in Vascular-PET:: Translational and Clinical Applications. Paravastu SS, Theng EH, Morris MA, Grayson P, Collins MT, Maass-Moreno R, Piri R, Gerke O, Alavi A, Flemming Høilund-Carlsen P, Edenbrandt L, Saboury B. PET Clin. 2022 Jan;17(1):95-113. doi: 10.1016/j.cpet.2021.09.003. PMID: 34809874
CAR T cells produced in vivo to treat cardiac injury. Rurik JG, Tombácz I, Yadegari A, Méndez Fernández PO, Shewale SV, Li L, Kimura T, Soliman OY, Papp TE, Tam YK, Mui BL, Albelda SM, Puré E, June CH, Aghajanian H, Weissman D, Parhiz H, Epstein JA. Science. 2022 Jan 7;375(6576):91-96. doi: 10.1126/science.abm0594. Epub 2022 Jan 6. PMID: 34990237
A novel assay to isolate and quantify third-stage Dirofilaria immitis and Brugia malayi larvae emerging from individual Aedes aegypti. McCrea AR, Edgerton EB, Oliver GT, O'Neill FM, Nolan TJ, Lok JB, Povelones M. Parasit Vectors. 2021 Jan 7;14(1):30. doi: 10.1186/s13071-020-04529-w. PMID: 33413579
Evolving Views of Long Noncoding RNAs and Epigenomic Control of Lymphocyte State and Memory. Morrison TA, Hudson WH, Chisolm DA, Kanno Y, Shih HY, Ahmed R, Henao-Mejia J, Hafner M, O'Shea JJ. Cold Spring Harb Perspect Biol. 2022 Jan 4;14(1):a037952. doi: 10.1101/cshperspect.a037952. PMID: 34001528
Schistosome TRPML channels play a role in neuromuscular activity and tegumental integrity. Bais S, Norwillo A, Ruthel G, Herbert DR, Freedman BD, Greenberg RM. Biochimie. 2022 Jan 3:S0300-9084(21)00306-0. doi: 10.1016/j.biochi.2021.12.018. Online ahead of print. PMID: 34990770
Inhibition of Orai Channel Function Regulates Mas-Related G Protein-Coupled Receptor-Mediated Responses in Mast Cells. Chaki S, Alkanfari I, Roy S, Amponnawarat A, Hui Y, Oskeritzian CA, Ali H. Front Immunol. 2022 Jan 20;12:803335. doi: 10.3389/fimmu.2021.803335. eCollection 2021. PMID: 35126366
Insights Into the Emergence of Paroxysmal Nocturnal Hemoglobinuria. Colden MA, Kumar S, Munkhbileg B, Babushok DV. Front Immunol. 2022 Jan 28;12:830172. doi: 10.3389/fimmu.2021.830172. eCollection 2021. PMID: 35154088
Eltrombopag: a springboard to early responses in SAA. Babushok DV. Blood. 2022 Jan 6;139(1):1-2. doi: 10.1182/blood.2021014046. PMID: 34989776
Nemo-Dependent, ATM-Mediated Signals from RAG DNA Breaks at IgkFeedback Inhibit V κ Recombination to Enforce Igκ Allelic Exclusion. Glynn RA, Bassing CH. J Immunol. 2022 Jan 15;208(2):371-383. doi: 10.4049/jimmunol.2100696. Epub 2021 Dec 29. PMID: 34965965
Circadian REV-ERBs repress E4bp4 to activate NAMPT-dependent NAD+biosynthesis and sustain cardiac function. Dierickx P, Zhu K, Carpenter BJ, Jiang C, Vermunt MW, Xiao Y, Luongo TS, Yamamoto T, Martí-Pàmies Í, Mia S, Latimer M, Diwan A, Zhao J, Hauck AK, Krusen B, Nguyen HCB, Blobel GA, Kelly DP, Pei L, Baur JA, Young ME, Lazar MA. Nat Cardiovasc Res. 2022 Jan;1(1):45-58. doi: 10.1038/s44161-021-00001-9. Epub 2021 Dec 23. PMID: 35036997
Human NAIP/NLRC4 and NLRP3 inflammasomes detect Salmonella type III secretion system activities to restrict intracellular bacterial replication. Naseer N, Egan MS, Reyes Ruiz VM, Scott WP, Hunter EN, Demissie T, Rauch I, Brodsky IE, Shin S. PLoS Pathog. 2022 Jan 24;18(1):e1009718. doi: 10.1371/journal.ppat.1009718. eCollection 2022 Jan. PMID: 35073381
Reduced-Intensity/Reduced-Toxicity Conditioning Approaches Are Tolerated in XIAP Deficiency but Patients Fare Poorly with Acute GVHD. Arnold DE, Nofal R, Wakefield C, Lehmberg K, Wustrau K, Albert MH, Morris EC, Heimall JR, Bunin NJ, Kumar A, Jordan MB, Cole T, Choo S, Brettig T, Speckmann C, Ehl S, Salamonowicz M, Wahlstrom J, Rao K, Booth C, Worth A, Marsh RA. J Clin Immunol. 2022 Jan;42(1):36-45. doi: 10.1007/s10875-021-01103-6. Epub 2021 Sep 29. PMID: 34586554
Long-term safety and efficacy of lentiviral hematopoietic stem/progenitor cell gene therapy for Wiskott-Aldrich syndrome. Magnani A, Semeraro M, Adam F, Booth C, Dupré L, Morris EC, Gabrion A, Roudaut C, Borgel D, Toubert A, Clave E, Abdo C, Gorochov G, Petermann R, Guiot M, Miyara M, Moshous D, Magrin E, Denis A, Suarez F, Lagresle C, Roche AM, Everett J, Trinquand A, Guisset M, Bayford JX, Hacein-Bey-Abina S, Kauskot A, Elfeky R, Rivat C, Abbas S, Gaspar HB, Macintyre E, Picard C, Bushman FD, Galy A, Fischer A, Six E, Thrasher AJ, Cavazzana M. Nat Med. 2022 Jan;28(1):71-80. doi: 10.1038/s41591-021-01641-x. Epub 2022 Jan 24. PMID: 35075289
Radiomic Phenotypes for Improving Early Prediction of Survival in Stage III Non-Small Cell Lung Cancer Adenocarcinoma after Chemoradiation. Luna JM, Barsky AR, Shinohara RT, Roshkovan L, Hershman M, Dreyfuss AD, Horng H, Lou C, Noël PB, Cengel KA, Katz S, Diffenderfer ES, Kontos D. Cancers (Basel). 2022 Jan 29;14(3):700. doi: 10.3390/cancers14030700. PMID: 35158971
Mesenchymal stromal cells enhance self-assembly of a HUVEC tubular network through uPA-uPAR/VEGFR2/integrin/NOTCH crosstalk. Beloglazova I, Stepanova V, Zubkova E, Dergilev K, Koptelova N, Tyurin-Kuzmin PA, Dyikanov D, Plekhanova O, Cines DB, Mazar AP, Parfyonova Y. Biochim Biophys Acta Mol Cell Res. 2022 Jan;1869(1):119157. doi: 10.1016/j.bbamcr.2021.119157. Epub 2021 Oct 4. PMID: 34619163
Repurposing ferumoxytol: Diagnostic and therapeutic applications of an FDA-approved nanoparticle. Huang Y, Hsu JC, Koo H, Cormode DP. Theranostics. 2022 Jan 1;12(2):796-816. doi: 10.7150/thno.67375. eCollection 2022. PMID: 34976214
PBJ celebrates twenty years of service to the scientific community by offering free global access, improved ranking and diversity. Daniell H. Plant Biotechnol J. 2022 Jan;20(1):3-9. doi: 10.1111/pbi.13757. PMID: 34957690
Mining for encrypted peptide antibiotics in the human proteome. Torres MDT, Melo MCR, Crescenzi O, Notomista E, de la Fuente-Nunez C. Nat Biomed Eng. 2022 Jan;6(1):67-75. doi: 10.1038/s41551-021-00801-1. Epub 2021 Nov 4. PMID: 34737399
A Randomized Phase II Study of Nivolumab Monotherapy or Nivolumab Combined with Ipilimumab in Patients with Advanced Gastrointestinal Stromal Tumors. Singh AS, Hecht JR, Rosen L, Wainberg ZA, Wang X, Douek M, Hagopian A, Andes R, Sauer L, Brackert SR, Chow W, DeMatteo R, Eilber FC, Glaspy JA, Chmielowski B. Clin Cancer Res. 2022 Jan 1;28(1):84-94. doi: 10.1158/1078-0432.CCR-21-0878. Epub 2021 Aug 18. PMID: 34407970
Regulation of the BCR signalosome by the class II peptide editor, H2-M, affects the development and repertoire of innate-like B cells. Ghosh D, Pham TD, Nanaware PP, Sengupta D, Adler LN, Li CG, He X, O'Mara ME, Kantor AB, Nguyen KD, Yang Y, Eisenlohr LC, Jensen PE, Herzenberg LA, Stern LJ, Boyd SD, Ghosn EEB, Mellins ED. Cell Rep. 2022 Jan 25;38(4):110200. doi: 10.1016/j.celrep.2021.110200. PMID: 35081339
Does biologic therapy impact the development of PsA among patients with psoriasis? Meer E, Merola JF, Fitzsimmons R, Love TJ, Wang S, Shin D, Chen Y, Xie S, Choi H, Zhang Y, Scher JU, Ritchlin CT, Gelfand JM, Ogdie A. Ann Rheum Dis. 2022 Jan;81(1):80-86. doi: 10.1136/annrheumdis-2021-220761. Epub 2021 Oct 6. PMID: 34615637
Heterologous ChAdOx1 nCoV-19 and BNT162b2 prime-boost vaccination elicits potent neutralizing antibody responses and T cell reactivity against prevalent SARS-CoV-2 variants. Groß R, Zanoni M, Seidel A, Conzelmann C, Gilg A, Krnavek D, Erdemci-Evin S, Mayer B, Hoffmann M, Pöhlmann S, Liu W, Hahn BH, Beil A, Kroschel J, Jahrsdörfer B, Schrezenmeier H, Kirchhoff F, Münch J, Müller JA .EBioMedicine. 2022 Jan;75:103761. doi: 10.1016/j.ebiom.2021.103761. Epub 2021 Dec 17. PMID: 34929493
Frontiers in Oral Mucosal Immunity and the Microbiome. Belibasakis GN, Hajishengallis G. Front Oral Health. 2022 Jan 3;2:821148. doi: 10.3389/froh.2021.821148. eCollection 2021. PMID: 35048081
Artificial Intelligence-based Tumor Segmentation in Mouse Models of Lung Adenocarcinoma. Arlova A, Jin C, Wong-Rolle A, Chen ES, Lisle C, Brown GT, Lay N, Choyke PL, Turkbey B, Harmon S, Zhao C. J Pathol Inform. 2022 Jan 20;13:100007. doi: 10.1016/j.jpi.2022.100007. eCollection 2022. PMID: 35242446
Kinetic dissection of macromolecular complex formation with minimally perturbing fluorescent probes. Cory MB, Hostetler ZM, Kohli RM. Methods Enzymol. 2022;664:151-171. doi: 10.1016/bs.mie.2022.01.009. Epub 2022 Jan 29. PMID: 35331372
The Rapid Implementation of Ad Hoc Tele-Critical Care Respiratory Therapy (eRT) Service in the Wake of the COVID-19 Surge. Pierce M, Gudowski SW, Roberts KJ, Jackominic A, Zumstein KK, Shuttleworth A, Ho J, Susser P, Parikh A, Chandler JM, Huffenberger AM, Scott MJ, Hanson CW 3rd, Laudanski K. J Clin Med. 2022 Jan 29;11(3):718. doi: 10.3390/jcm11030718. PMID: 35160170
Considerations for Cannabinoids in Perioperative Care by Anesthesiologists. Laudanski K, Wain J. J Clin Med. 2022 Jan 22;11(3):558. doi: 10.3390/jcm11030558. PMID: 35160010
A review of signaling and transcriptional control in T follicular helper cell differentiation. Hart AP, Laufer TM. J Leukoc Biol. 2022 Jan;111(1):173-195. doi: 10.1002/JLB.1RI0121-066R. Epub 2021 Apr 18. PMID: 33866600
FZD2 Regulates Murine Hair Follicle Function and Maintenance. Brennan-Crispi DM, Frankfurter M, Murphy C, Sheng E, Xu M, Morrisey EE, Millar SE, Leung TH .J Invest Dermatol. 2022 Jan 17:S0022-202X(22)00011-2. doi: 10.1016/j.jid.2022.01.004. Online ahead of print. PMID: 35051380
A Murine Model of X-Linked Moesin-Associated Immunodeficiency (X-MAID) Reveals Defects in T Cell Homeostasis and Migration. Avery L, Robertson TF, Wu CF, Roy NH, Chauvin SD, Perkey E, Vanderbeck A, Maillard I, Burkhardt JK. Front Immunol. 2022 Jan 6;12:726406. doi: 10.3389/fimmu.2021.726406. eCollection 2021. PMID: 35069520
Patient Perceptions and Preferences Regarding Telemedicine for Autoimmune Rheumatic Diseases Care During the COVID-19 Pandemic. Danila MI, Gavigan K, Rivera E, Nowell WB, George MD, Curtis JR, Christopher-Stein L, Banerjee S, Merkel PA, Young K, Shaw DG, Gordon J, Venkatachalam S. Arthritis Care Res (Hoboken). 2022 Jan 18:10.1002/acr.24860. doi: 10.1002/acr.24860. Online ahead of print. PMID: 35040274
Use of 18F-fluorodeoxyglucose Positron Emission Tomography to Standardize Clinical Trial Recruitment in Takayasu's Arteritis. Quinn KA, Alessi H, Ponte C, Rose E, Ahlman MA, Redmond C, Luo Y, Bolek EC, Langford CA, Merkel PA, Grayson PC. Rheumatology (Oxford). 2022 Jan 12:keac021. doi: 10.1093/rheumatology/keac021. Online ahead of print. PMID: 35022691
The Minority Scientists' Experience: Challenging and Overcoming Barriers to Enhancing Diversity and Career Advancement. Webb TJ, Guerau-de-Arellano M, Jones HP, Butts CL, Sanchez-Perez L, Montaner LJ. J Immunol. 2022 Jan 15;208(2):197-202. doi: 10.4049/jimmunol.2101077. PMID: 35017208
Uncommon variants in FLG2 and TCHHL1 are associated with remission of atopic dermatitis in a large longitudinal US cohort. Berna R, Mitra N, Hoffstad O, Wubbenhorst B, Nathanson KL, Margolis D J.Arch Dermatol Res. 2022 Jan 4. doi: 10.1007/s00403-021-02319-7. Online ahead of print. PMID: 34984527
Sweet Immune Checkpoint Targets to Enhance T Cell Therapy. Derosiers N, Aguilar W, DeGaramo DA, Posey AD Jr. J Immunol. 2022 Jan 15;208(2):278-285. doi: 10.4049/jimmunol.2100706. PMID: 35017217
Dermatologic Events Associated with the Anti-CCR4 Antibody Mogamulizumab: Characterization and Management. Musiek ACM, Rieger KE, Bagot M, Choi JN, Fisher DC, Guitart J, Haun PL, Horwitz SM, Huen AO, Kwong BY, Lacouture ME, Noor SJ, Rook AH, Seminario-Vidal L, Vermeer MH, Kim YH .Dermatol Ther (Heidelb). 2022 Jan;12(1):29-40. doi: 10.1007/s13555-021-00624-7. Epub 2021 Nov 23. PMID: 34816383
CD73+ Epithelial Progenitor Cells That Contribute to Homeostasis and Renewal Are Depleted in Eosinophilic Esophagitis. Hara T, Kasagi Y, Wang J, Sasaki M, Aaron B, Karami A, Shimonosono M, Shimonosono R, Maekawa H, Dolinsky L, Wilkins B, Klein J, Wei J, Nunes K, Lynch K, Spergel JM, Hamilton KE, Ruffner MA, Karakasheva TA, Whelan KA, Nakagawa H, Muir AB. Cell Mol Gastroenterol Hepatol. 2022;13(5):1449-1467. doi: 10.1016/j.jcmgh.2022.01.018. Epub 2022 Jan 30. PMID: 35108658
Potent anti-viral activity of a trispecific HIV neutralizing antibody in SHIV-infected monkeys. Pegu A, Xu L, DeMouth ME, Fabozzi G, March K, Almasri CG, Cully MD, Wang K, Yang ES, Dias J, Fennessey CM, Hataye J, Wei RR, Rao E, Casazza JP, Promsote W, Asokan M, McKee K, Schmidt SD, Chen X, Liu C, Shi W, Geng H, Foulds KE, Kao SF, Noe A, Li H, Shaw GM, Zhou T, Petrovas C, Todd JP, Keele BF, Lifson JD, Doria-Rose NA, Koup RA, Yang ZY, Nabel GJ, Mascola JR. Cell Rep. 2022 Jan 4;38(1):110199. doi: 10.1016/j.celrep.2021.110199. PMID: 34986348
Efficacy and safety of a novel mucoadhesive clobetasol patch for treatment of erosive oral lichen planus: A phase 2 randomized clinical trial. Brennan MT, Madsen LS, Saunders DP, Napenas JJ, McCreary C, Ni Riordain R, Pedersen AML, Fedele S, Cook RJ, Abdelsayed R, Llopiz MT, Sankar V, Ryan K, Culton DA, Akhlef Y, Castillo F, Fernandez I, Jurge S, Kerr AR, McDuffie C, McGaw T, Mighell A, Sollecito TP, Schlieve T, Carrozzo M, Papas A, Bengtsson T, Al-Hashimi I, Burke L, Burkhart NW, Culshaw S, Desai B, Hansen J, Jensen P, Menné T, Patel PB, Thornhill M, Treister N, Ruzicka T. J Oral Pathol Med. 2022 Jan;51(1):86-97. doi: 10.1111/jop.13270. Epub 2022 Jan 13. PMID: 34907617
Numbers and narratives: how qualitative methods can strengthen the science of paediatric antimicrobial stewardship. Woods-Hill CZ, Xie A, Lin J, Wolfe HA, Plattner AS, Malone S, Chiotos K, Szymczak JE .JAC Antimicrob Resist. 2022 Jan 22;4(1):dlab195. doi: 10.1093/jacamr/dlab195. eCollection 2022 Mar. PMID: 35098126
SARS-CoV-2 DNA Vaccine INO-4800 Induces Durable Immune Responses Capable of Being Boosted in a Phase 1 Open-Label Trial. Kraynyak KA, Blackwood E, Agnes J, Tebas P, Giffear M, Amante D, Reuschel EL, Purwar M, Christensen-Quick A, Liu N, Andrade VM, Diehl MC, Wani S, Lupicka M, Sylvester A, Morrow MP, Pezzoli P, McMullan T, Kulkarni AJ, Zaidi FI, Frase D, Liaw K, Smith TRF, Ramos SJ, Ervin J, Adams M, Lee J, Dallas M, Brown AS, Shea JE, Kim JJ, Weiner DB, Broderick KE, Humeau LM, Boyer JD, Mammen MP.J Infect Dis. 2022 Jan 25:jiac016. doi: 10.1093/infdis/jiac016. Online ahead of print.PMID: 35079784
Association of Convalescent Plasma Treatment With Clinical Status in Patients Hospitalized With COVID-19: A Meta-analysis. Troxel AB, Petkova E, Goldfeld K, Liu M, Tarpey T, Wu Y, Wu D, Agarwal A, Avendaño-Solá C, Bainbridge E, Bar KJ, Devos T, Duarte RF, Gharbharan A, Hsue PY, Kumar G, Luetkemeyer AF, Meyfroidt G, Nicola AM, Mukherjee A, Ortigoza MB, Pirofski LA, Rijnders BJA, Rokx C, Sancho-Lopez A, Shaw P, Tebas P, Yoon HA, Grudzen C, Hochman J, Antman EM. JAMA Netw Open. 2022 Jan 4;5(1):e2147331. doi: 10.1001/jamanetworkopen.2021.47331. PMID: 35076699
Automatic upper airway segmentation in static and dynamic MRI via anatomy-guided convolutional neural networks. Xie L, Udupa JK, Tong Y, Torigian DA, Huang Z, Kogan RM, Wootton D, Choy KR, Sin S, Wagshul ME, Arens R. Med Phys. 2022 Jan;49(1):324-342. doi: 10.1002/mp.15345. Epub 2021 Dec 2. PMID: 34773260
Rapid Production of Bispecific Antibodies from Off-the-Shelf IgGs with High Yield and Purity. Mei L, Zappala F, Tsourkas A. Bioconjug Chem. 2022 Jan 19;33(1):134-141. doi: 10.1021/acs.bioconjchem.1c00476. Epub 2021 Dec 12. PMID: 34894663
Evolution of FMT - From early clinical to standardized treatments. Servetas SL, Daschner PJ, Guyard C, Thomas V, Affagard H, Sergaki C, Sokol H, Wargo JA, Wu GD, Sabot P. Biologicals. 2022 Jan 24:S1045-1056(22)00004-5. doi: 10.1016/j.biologicals.2022.01.004. Online ahead of print. PMID: 35086768
Causes of readmissions for patients discharged on enteral nutrition. Palchaudhuri S, Mehta SJ, Snider CK, Parsikia A, Hudson L, Compher C, Lewis JD, Wu GD, Pickett-Blakely O. JPEN J Parenter Enteral Nutr. 2022 Jan 18. doi: 10.1002/jpen.2331. Online ahead of print. PMID: 35040141

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