Penn Institute for Immunology

• Wang HH, Altun B, Nwe K, Tsourkas A. Proximity-Based Sortase-Mediated Ligation. Angew Chem Int Ed Engl. 2017 May 2;56(19):5349-5352.  PMID: 28374553
• Smith TRF, Schultheis K, Morrow MP, Kraynyak KA, McCoy JR, Yim KC, Muthumani K, Humeau L, Weiner DB, Sardesai NY, Broderick KE. Development of an intradermal DNA vaccine delivery strategy to achieve single-dose immunity against respiratory syncytial virus. Vaccine. 2017 May 15;35(21):2840-2847.  PMID: 28413132
• Leiman DA, Riff BP, Morgan S, Metz DC, Falk GW, French B, Umscheid CA, Lewis JD.  Alginate therapy is effective treatment for GERD symptoms: a systematic review and meta-analysis.  Dis Esophagus. 2017 May 1;30(5):1-9.  PMID: 28375448
• Khera AV, Demler O, Adelman SJ, Collins HL, Glynn RJ, Ridker PM, Rader DJ, Mora S.  Cholesterol Efflux Capacity, HDL Particle Number, and Incident Cardiovascular Events. An Analysis from the JUPITER Trial (Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin).  Circulation. 2017 Apr 27.  PMID: 28450350

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• Baldwin MR, Singer JP, Huang D, Sell J, Gonzalez WC, Pollack L, Maurer MS, D'Ovidio FF, Bacchetta M, Sonett JR, Arcasoy SM, Shah L, Robbins H, Hays SR, Kukreja J, Greenland JR, Shah RJ, Leard L, Morrell M, Gries C, Katz PP, Christie JD, Diamond JM, Lederer DJ.  Refining Low Physical Activity Measurement Improves Frailty Assessment in Advanced Lung Disease and Survivors of Critical Illness.  Ann Am Thorac Soc. 2017 Apr 11. PMID: 28398076
• Putra J, Gupta A. Kaposiform haemangioendothelioma: a review with emphasis on histological differential diagnosis.  Pathology. 2017 Apr 21. PMID: 28438388
• Spitsin S, Meshki J, Winters A, Tuluc F, Benton TD, Douglas SD.  Substance P-mediated chemokine production promotes monocyte migration.  J. Leukoc Biol. 2017 Apr;101(4):967-973. PMID: 28366881
• Ogdie A, Kay McGill N, Shin DB, Takeshita J, Jon Love T, Noe MH, Chiesa Fuxench ZC, Choi HK, Mehta NN, Gelfand JM. Risk of venous thromboembolism in patients with psoriatic arthritis, psoriasis and rheumatoid arthritis: a general population-based cohort study.  Eur Heart J. 2017 Apr 20. PMID: 28444172
• Abuabara K, Magyari AM, Hoffstad O, Jabbar-Lopez ZK, Smeeth L, Williams HC, Gelfand JM, Margolis DJ, Langan SM. Development and validation of an algorithm to accurately identify atopic eczema patients in primary care electronic health records from the UK.  J Invest Dermatol. 2017 Apr 18.  PMID: 28428130
• Liang JJ, Betensky BP, Muser D, Zado ES, Anter E, Desai ND, Callans DJ, Deo R, Frankel DS, Hutchinson MD, Lin D, Riley MP, Schaller RD, Supple GE, Santangeli P, Acker MA, Bavaria JE, Szeto WY, Vallabhajosyula P, Marchlinski FE, Dixit S. Long-term outcome of surgical cryoablation for refractory ventricular tachycardia in patients with non-ischemic cardiomyopathy.  Europace. 2017 Apr 10. PMID: 28402404
• Rauch I, Deets KA, Ji DX, von Moltke J, Tenthorey JL, Lee AY, Philip NH, Ayres JS, Brodsky IE, Gronert K, Vance RE. NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8. Immunity. 2017 Apr 18;46(4):649-659.  PMID: 28410991
• Huang AC, Postow MA, Orlowski RJ, Mick R, Bengsch B, Manne S, Xu W, Harmon S, Giles JR, Wenz B, Adamow M, Kuk D, Panageas KS, Carrera C, Wong P, Quagliarello F, Wubbenhorst B, D'Andrea K, Pauken KE, Herati RS, Staupe RP, Schenkel JM, McGettigan S, Kothari S, George SM, Vonderheide RH, Amaravadi RK, Karakousis GC, Schuchter LM, Xu X, Nathanson KL, Wolchok JD, Gangadhar TC, Wherry EJ. T-cell invigoration to tumour burden ratio associated with anti-PD-1 response.  Nature. 2017 Apr 10.  PMID: 28397821
• Cines DB, Wasser J, Rodeghiero F, Chong BH, Steurer M, Provan D, Lyons R, Garcia-Chavez J, Carpenter N, Wang X, Eisen M.  Safety and efficacy of romiplostim in splenectomized and nonsplenectomized patients with primary immune thrombocytopenia. Haematologica. 2017 Apr 14.  PMID: 28411254
• Katerndahl CDS, Heltemes-Harris LM, Willette MJL, Henzler CM, Frietze S, Yang R, Schjerven H, Silverstein KAT, Ramsey LB, Hubbard G, Wells AD, Kuiper RP, Scheijen B, van Leeuwen FN, Müschen M, Kornblau SM, Farrar MA. Antagonism of B cell enhancer networks by STAT5 drives leukemia and poor patient survival. Nat Immunol. 2017 Apr 3. PMID: 28369050
• Knox JJ, Buggert M, Kardava L, Seaton KE, Eller MA, Canaday DH, Robb ML, Ostrowski MA, Deeks SG, Slifka MK, Tomaras GD, Moir S, Moody MA, Betts MR. T-bet+ B cells are induced by human viral infections and dominate the HIV gp140 response. JCI Insight. 2017 Apr 20;2(8). PMID: 28422752
• O'Brien CA, Overall C, Konradt C, O'Hara Hall AC, Hayes NW, Wagage S, John B, Christian DA, Hunter CA, Harris TH. CD11c-Expressing Cells Affect Regulatory T Cell Behavior in the Meninges during Central Nervous System Infection. J Immunol. 2017 Apr 7. PMID: 28389591
• Angelin A, Gil-de-Gómez L, Dahiya S, Jiao J, Guo L, Levine MH, Wang Z, Quinn WJ 3rd, Kopinski PK, Wang L, Akimova T, Liu Y, Bhatti TR, Han R, Laskin BL, Baur JA, Blair IA, Wallace DC, Hancock WW, Beier UH.  Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments. Cell Metab. 2017 Apr 11. pii: S1550-4131(16)30651-9.  PMID: 28416194
• Hatemi G, Meara A, Ozguler Y, Direskeneli H, Mahr A, Easley E, Gurcan M, Davis T, Gul A, Yazici Y, Zottenberg K, Esatoglu SN, Erer B, Kamali S, Yazici H, Cronholm PF, Merkel PA. Developing a Core Set of Outcome Measures for Behçet Disease: Report from OMERACT 2016.  J Rheumatol. 2017 Apr 1. P PMID: 28365574
• Smith JR, Winkelstein BA. The role of spinal thrombin through protease-activated receptor 1 in hyperalgesia after neural injury.  J Neurosurg Spine. 2017 Apr;26(4):532-541. PMID: 28059686
• Arruda VR. Stopping bleeding is not enough to FIX hemarthropathy. Blood. 2017 Apr 13;129(15):2048-2049. PMID: 28408422
• Lim MA, Palmer M, Trofe-Clark J, Bloom RD, Jackson A, Philogene MC, Kamoun M. Histopathologic changes in anti-angiotensin II type 1 receptor antibody-positive kidney transplant recipients with acute rejection and no donor specific HLA antibodies. Hum Immunol. 2017 Apr;78(4):350-356. PMID: 28284829
• Koenig HC, Mounzer K, Daughtridge GW, Sloan CE, Lalley-Chareczko L, Moorthy GS, Conyngham SC, Zuppa AF, Montaner LJ, Tebas P.  Urine assay for tenofovir to monitor adherence in real time to tenofovir disoproxil fumarate/emtricitabine as pre-exposure prophylaxis. HIV Med. 2017 Apr 26.  PMID: 28444867
• Papasavvas E, Azzoni L, Yin X, Liu Q, Joseph J, Mackiewicz A, Ross B, Lynn KM, Jacobson JM, Mounzer K, Kostman JR, Montaner LJ. HCV viremia associates with NK cell activation and dysfunction in anti retroviral HIV/HCV co-infected subjects.  J Viral Hepat. 2017 Apr 17. PMID: 28419653
• Afkhami S, LeClair DA, Haddadi S, Lai R, Toniolo SP, Ertl HC, Cranston ED, Thompson MR, Xing Z.  Spray dried human and chimpanzee adenoviral-vectored vaccines are thermally stable and immunogenic in vivo. Vaccine. 2017 Apr 21. PMID: 28438408
• Ertl HCJ, High KA. Impact of AAV Capsid-Specific T-Cell Responses on Design and Outcome of Clinical Gene Transfer Trials with Recombinant Adeno-Associated Viral Vectors: An Evolving Controversy.  Hum Gene Ther. 2017 Apr;28(4):328-337. PMID: 28042943
• Yan L, Miller J, Yuan M, Liu JF, Busch TM, Tsourkas A, Cheng Z. Improved Photodynamic Therapy Efficacy of Protoporphyrin IX Loaded Polymeric Micelles Using Erlotinib Pretreatment.  Biomacromolecules. 2017 Apr 24. PMID: 28437090
• Drake MJ, Brennan B, Briley K Jr, Bart SM, Sherman E, Szemiel AM, Minutillo M, Bushman FD, Bates P.  A role for glycolipid biosynthesis in severe fever with thrombocytopenia syndrome virus entry.  PLoS Pathog. 2017 Apr 7;13(4):e1006316.  PMID: 28388693
• Etienne-Mesmin L, Chassaing B, Adekunle O, Mattei LM, Edwards AN, McBride SM, Bushman FD, Gewirtz AT.  Genome Sequence of a Toxin-Positive <i>Clostridium difficile</i> Strain Isolated from Murine Feces. Genome Announc. 2017 Apr 6;5(14). PMID: 28385835
• Glennie ND, Volk SW, Scott P. Skin-resident CD4+ T cells protect against Leishmania major by recruiting and activating inflammatory monocytes. PLoS Pathog. 2017 Apr 18;13(4):e1006349. PMID: 28419151
• Murken DR, Peng AW, Aufhauser DD Jr, Abt PL, Goldberg DS, Levine MH.  Same Policy, Different Impact: Center-Level Effects of Share 35 Liver Allocation.  Liver Transpl. 2017 Apr 13.  PMID: 28407441
• Baldwin MR, Singer JP, Huang D, Sell J, Gonzalez WC, Pollack L, Maurer MS, D'Ovidio FF, Bacchetta M, Sonett JR, Arcasoy SM, Shah L, Robbins H, Hays SR, Kukreja J, Greenland JR, Shah RJ, Leard L, Morrell M, Gries C, Katz PP, Christie JD, Diamond JM, Lederer DJ.  Refining Low Physical Activity Measurement Improves Frailty Assessment in Advanced Lung Disease and Survivors of Critical Illness.  Ann Am Thorac Soc. 2017 Apr 11.  PMID: 28398076
• Casson CN, Doerner JL, Copenhaver AM, Ramirez J, Holmgren AM, Boyer MA, Siddarthan IJ, Rouhanifard SH, Raj A, Shin S.  Neutrophils and Ly6Chi monocytes collaborate in generating an optimal cytokine response that protects against pulmonary Legionella pneumophila infection.  PLoS Pathog. 2017 Apr 6;13(4):e1006309.  PMID: 28384349
• Schmidt E, Spindler V, Eming R, Amagai M, Antonicelli F, Baines JF, Belheouane M, Bernard P, Borradori L, Caproni M, Di Zenzo G, Grando S, Harman K, Jonkman MF, Koga H, Ludwig RJ, Kowalczyk AP, Müller EJ, Nishie W, Pas H, Payne AS, Sadik CD, Seppänen A, Setterfield J, Shimizu H, Sinha AA, Sprecher E, Sticherling M, Ujiie H, Zillikens D, Hertl M, Waschke J.  Meeting Report of the Pathogenesis of Pemphigus and Pemphigoid Meeting in Munich, September 2016. J Invest Dermatol. 2017 Apr 5. pii: S0022-202X(17)30173-2.  PMID: 28390814
• Knox JJ, Buggert M, Kardava L, Seaton KE, Eller MA, Canaday DH, Robb ML, Ostrowski MA, Deeks SG, Slifka MK, Tomaras GD, Moir S, Moody MA, Betts MR. T-bet+ B cells are induced by human viral infections and dominate the HIV gp140 response. JCI Insight. 2017 Apr 20;2(8). pii: 92943. PMID: 28422752
• Döring Y, Noels H, van der Vorst EPC, Neideck C, Egea V, Drechsler M, Mandl M, Pawig LB, Jansen Y, Schröder K, Bidzhekov K, Megens RTA, Theelen W, Klinkhammer BM, Boor P, Schurgers LJ, van Gorp RH, Ries C, Kusters PJH, van der Wal AC, Hackeng TM, Gäbel G, Brandes RP, Soehnlein O, Lutgens E, Vestweber D, Teupser D, Holdt LM, Rader DJ, Saleheen D, Weber C.  Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence from Mouse and Human Studies.  Circulation. 2017 Apr 27. PMID: 28450349
• Saleheen D, Haycock PC, Zhao W, Rasheed A, Taleb A, Imran A, Abbas S, Majeed F, Akhtar S, Qamar N, Zaman KS, Yaqoob Z, Saghir T, Rizvi SN, Memon A, Mallick NH, Ishaq M, Rasheed SZ, Memon FU, Mahmood K, Ahmed N, Frossard P, Tsimikas S, Witztum JL, Marcovina S, Sandhu M, Rader DJ, Danesh J.  Apolipoprotein(a) isoform size, lipoprotein(a) concentration, and coronary artery disease: a mendelian randomisation analysis.  Lancet Diabetes Endocrinol. 2017 Apr 10. pii: S2213-8587(17)30088-8. doi: 10.1016/S2213-8587(17)30088-8.  PMID: 28408323
• Saleheen D, Natarajan P, Armean IM, Zhao W, Rasheed A, Khetarpal SA, Won HH, Karczewski KJ, O'Donnell-Luria AH, Samocha KE, Weisburd B, Gupta N, Zaidi M, Samuel M, Imran A, Abbas S, Majeed F, Ishaq M, Akhtar S, Trindade K, Mucksavage M, Qamar N, Zaman KS, Yaqoob Z, Saghir T, Rizvi SNH, Memon A, Hayyat Mallick N, Ishaq M, Rasheed SZ, Memon FU, Mahmood K, Ahmed N, Do R, Krauss RM, MacArthur DG, Gabriel S, Lander ES, Daly MJ, Frossard P, Danesh J, Rader DJ, Kathiresan S. Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity. Nature. 2017 Apr 12;544(7649):235-239.  PMID: 28406212
• Tiao J, Feng R, Berger EM, Brandsema JF, Coughlin CC, Khan N, Kichula EA, Lerman MA, Lvovich S, McMahon PJ, Rider LG, Rubin AI, Scalzi LV, Smith DM, Taxter AJ, Treat JR, Williams RP, Yum SW, Okawa J, Werth VP.  Evaluation of the Reliability of the Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI) and the Cutaneous Assessment Tool Binary Method (CAT-BM) in Juvenile Dermatomyositis Among Pediatric Dermatologists, Rheumatologists, and Neurologists.  Br J Dermatol. 2017 Apr 19. doi: 10.1111/bjd.15596.  PMID: 28421601
• Chansky PB, Werth VP.  Accidental hydroxychloroquine overdose resulting in neurotoxic vestibulopathy.  BMJ Case Rep. 2017 Apr 12;2017. pii: bcr-2016-218786.  PMID: 28404567
• Miller MP, Kostakoglu L, Pryma D, Yu JQ, Chau A, Perlman E, Clarke B, Rosen D, Ward P.  Reader training for the re-staging of biochemically recurrent prostate cancer using fluciclovine (¹⁸F) PET/CT.  J Nucl Med. 2017 Apr 6. pii: jnumed.116.188375. PMID: 28385791
• Sullivan KE, Rojas K, Cerione RA, Nakano I, Wilson KF.  The stem cell/cancer stem cell marker ALDH1A3 regulates the expression of the survival factor tissue transglutaminase, in mesenchymal glioma stem cells.  Oncotarget. 2017 Apr 4;8(14):22325-22343.  PMID: 28423611
• Döring Y, Noels H, van der Vorst EPC, Neideck C, Egea V, Drechsler M, Mandl M, Pawig LB, Jansen Y, Schröder K, Bidzhekov K, Megens RTA, Theelen W, Klinkhammer BM, Boor P, Schurgers LJ, van Gorp RH, Ries C, Kusters PJH, van der Wal AC, Hackeng TM, Gäbel G, Brandes RP, Soehnlein O, Lutgens E, Vestweber D, Teupser D, Holdt LM, Rader DJ, Saleheen D, Weber C.  Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence from Mouse and Human Studies.  Circulation. 2017 Apr 27.  PMID: 28450349
• Pashos EE, Park Y, Wang X, Raghavan A, Yang W, Abbey D, Peters DT, Arbelaez J, Hernandez M, Kuperwasser N, Li W, Lian Z, Liu Y, Lv W, Lytle-Gabbin SL, Marchadier DH, Rogov P, Shi J, Slovik KJ, Stylianou IM, Wang L, Yan R, Zhang X, Kathiresan S, Duncan SA, Mikkelsen TS, Morrisey EE, Rader DJ, Brown CD, Musunuru K.  Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci.  Cell Stem Cell. 2017 Apr 6;20(4):558-570.e10.  PMID: 28388432

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• Makeshita J, Grewal S, Langan SM, Mehta NN, Ogdie A, Van Voorhees AS, Gelfand JM.  Psoriasis and comorbid diseases: Implications for management.  J Am Acad Dermatol. 2017 Mar;76(3):393-403. PMID: 28212760
• Makeshita J, Grewal S, Langan SM, Mehta NN, Ogdie A, Van Voorhees AS, Gelfand JM. Psoriasis and comorbid diseases: Epidemiology.  J Am Acad Dermatol. 2017 Mar;76(3):377-390.  PMID: 28212759
• Alavi A, Werner TJ.  FDG-PET imaging to detect and characterize infectious disorders; an unavoidable path for the foreseeable future. Eur J Nucl Med Mol Imaging. 2017 Mar;44(3):417-420. PMID: 28039496
• Eftekhari K, Vagefi MR, Lee V, Hui JZ, Zhu M, Dine K, Anderson RL, Koeberlein B, Sulaimankutty R, Shindler KS. In Vivo Effects of Retrobulbar Bimatoprost Injection on Orbital Fat.  Ophthal Plast Reconstr Surg. 2017 Mar 31 PMID: 28369019

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