Research Interests: Connective tissue disease, immune dysregulation, inflammatory degenerative processes, degenerative joint disease, fibrosis, arthritis
Research Experience: Hung Lab (Cellular Engineering Laboratory)

Research Interests: immune cells, such as dendritic cells, T cells, and B cells, specifically around the molecular mechanisms that drive their behavior and function
during development or disease
Research Experience: Carpenter Lab (UCSC), Ansel Lab (UCSF)

Research Interests: autoimmunity, cancer immunology, genomics, machine learning
Research Experience: Thermo-Fisher, Invitae, Bioverativ, Gene Yeo Lab (UCSD)

Research Interests: Cancer immunology, T cell biology, T cell engineering, immunotherapies
Research Experience: Kalbasi, Ribas, and Zamudio Labs (UCLA Biomed)

Research Interests: virology, immunology, and emerging infectious diseases
Research Experience: Stortz Lab (NIH), Amemiya Lab (UC-Merced)

Research Interests: Translational immunology, cancer immunotherapies
Research Experience: Broad Institute of MIT & Harvard, EMSL Analytical Inc.

Research Interests: developing cancer immunotherapeutics; how leukocytes interact
with their environment, particularly in the context of cancer immunosurveillance/
immunotherapy and immune homeostasis
Research Experience: PDX Pharmaceuticals, Rockey Lab (Oregon State), Turker Lab (Oregon Health & Science)

Research Interests: innate immunology, autoimmune diseases, infectious diseases,
molecular pathogenesis, and host-pathogen interactions
Research Experience: Ileana Rodriguez Lab (Univ PR), Kate Fitzgerald Lab (UMass)

Research Interests: understanding the potential role pathogen-specific T cells play in tumor control and identifying regulators of hypoxia-induced chromatin changes
Research Experience: Rutgers Cancer Institute, New Jersey Institute of Technology

Research Interests: maternal-fetal immunology, host-pathogen interactions, microbial pathogenesis, infectious disease, immune responses at barrier sites, immune system development, and immunoregulation
Research Experience: Jurado Lab (Penn), Schoggins, Reese, Koh Labs (UT), Mitchell and Goeffroy Labs (Texas A&M)

Research Interests: human immune responses to vaccination and natural infection
Research Experience: Douek Lab (NIH), Masopust and Schmidt-Dannert Labs (U Minnesota)

Research Interests: cancer immunology, and specifically immunotherapies of cancer, such as cancer vaccination, CAR T cells, and immune checkpoint blockade
Research Experience: Wu Lab (Dana-Farber Cancer Inst), Hacohen Lab (Broad Institute), Yang Lab (Penn)

Research Interests: adaptive immune response associated with infectious and/or autoimmune diseases
Research Experience: Andrews & McDermott Lab (NIH) Zhang, Varani & Walker Labs (UW)

Research Interests: host-pathogen interactions, immune response, effector function, infections
Research Experience: Singer Lab (NIH), Wynne Lab (U Portland), Nishimura Lab (Colorado State)

Research Interests: translational immunology, tumor immunology, cancer immunotherapy and molecular and cellular biology of the immune system
Research Experience: SUIP-CCI Scholar (Fraietta Lab), U Delaware Summer Program

Research Interests: tumor/cancer immunology, neuroimmunology, and translational immunology
Research Experience: Haydel Lab (AZ State), Bergsagel Lab (Mayo Clinic)

Research Interests
Cancer immunology and immunotherapy; utilizing the immune system to develop new therapies and discovering the pathways to tumor malignancy.

Research Interests
Immune cell types which are functionally critical for clearing infections and how those functions are regulated.

Research Interests
CD4+ T and B cell responses in the context of infections, vaccination, and disease.

Research Interests
T Cell Immunology, Adaptive Immunity, Autoimmunity, and CAR T Cell Therapy.

Research Interests
Immunopharmacology, pharmacomicrobiomics, immunotherapy, effect of therapeutic options on immune system, host immunity modulation by microbes.

Research Interests
Exploring how our immune system fights off infections. More specifically, how certain pathogens are able to bypass our immune system and cause serious illnesses.

Research Interests
Cancer immunotherapies, tumor immunology, mechanisms of immune suppression in tumors, mechanisms of immune activation, bioinformatics, imaging, cytokines

Research Interests
 Translational immunology, cancer immunotherapies, t cell and b cell immunology, and cancer biology

Research Interests
Cancer Immunology, Viral Immunology, T Cells, Computational Immunology, Novel

Research Interests
Function, regulation, and response of B and T lymphocytes. Adaptive immunity in context of infectious diseases and autoimmunity. Viral immunology and immunotherapy

Research Interests

- Induction of T follicular helper cells
- Germinal center B cells and B cell maturation
- Vaccine-induced immune responses 

Meng received his B.S in biochemistry and computer science from the University of Wisconsin – Madison in 2018. His research interests manifested in the lab of Anna Huttenlocher, where he completed his senior thesis on the role of innate immune cells in the glioblastoma tumor microenvironment. Taking summer sabbaticals to different research groups (and countries), Meng explored his interests in various fields, including regenerative medicine (with Kris Saha), collective cell behaviors (at EMBL under the guidance of Darren Gilmour), and spheroid modeling of cancer metastasis (with Laura Kaufmann as a Columbia AMGEN scholar). Post-graduation, Meng spent two years in the lab of Ron Germain as a NIH IRTA fellow looking at clonal T-cell microstates. Outside of research, Meng has a passion for music, puzzles, high-adrenaline sports, and technology.

Jeremy received his BS in Biology with a concentration in Health Sciences at Emmanuel College in Boston in 2018. At Emmanuel, he was a part of the NeuroImmunology Research Project (NIRP) with Dr. Josef Kurtz and Dr. Todd Williams studying the hematopoietic contribution to CNS macrophage populations under various conditions. Following graduation, he joined the Center for Transplantation Sciences at Massachusetts General Hospital studying mechanisms of induced tolerance to cardiothoracic allografts with Dr. Joren Madsen. Jeremy was an integral part of many projects from studying the effect of immunosuppressive agents on the B cell compartment to developing donor-specific CAR-Tregs for future in vivo use. Although Jeremy has a continued interest in transplant immunology, he hopes to explore different areas of immunology at Penn as well. In his free time, he enjoys spending time with his fiancée and their chihuahua, whether they are hiking or biking along the river.

Sam grew up in Painted Post, NY and went to school just up the road at Cornell University. There, he spent two years working in a soil science lab. However, he fell in love with biochemistry and molecular biology and decided to do a postbac at the NIH exploring biomedical research. Sam joined Dr. Mike Lenardo’s lab in NIAID where he worked to uncover the molecular basis or rare genetic diseases. His work included redefining XMEN disease as a congenital disorder to glycosylation and discovering a novel genetic cause of IBD. During the COVID pandemic, Sam switched gears and worked with Dr. Helen Su’s lab to understand the role of host genetics in susceptibility to severe COVID infection as part of the COVID human genetics effort consortium. At the UPenn, Sam would like to learn how to use animal models and big data (omics) experiments to discover the molecular mechanisms of immune responses.

Originally from a suburb of Chicago, Joy received her B.S. in molecular biology from Yale University in 2019. Her undergraduate research interests were varied, from work at Gilead studying viral integrations in the human genome to her thesis in Choukri Ben Mamoun's lab on antifungal drug development. Following graduation, Joy remained in Dr. Ben Mamoun's lab to continue work studying the development of Babesia parasites and formulating new therapeutic strategies. At Penn, Joy hopes to continue her exploration of host-pathogen interactions, but with a new focus on host defense mechanisms. Outside of work, she loves to make music with friends, find new running trails, and accumulate cookbooks for her bookshelf.

Maria is from Gainesville, Florida, although she has been going home to Chattanooga, TN, to visit her family since they moved there a few years ago. Maria received a BA in chemistry from the University of Chicago, where she worked on an autoimmune disease imaging project under Dr. Marcus Clark. A summer research experience at MD Anderson Cancer Center sparked her interest in cancer biology. After graduating, Maria spent a year working in the lab of Dr. Robert Seder at the Vaccine Research Center at the NIH, where she worked on novel methods of delivering immunostimulatory drugs to tumors. In her graduate work at Penn, Maria hopes to research the tumor microenvironment and anti-tumor immunity with the goal of elucidating targets for cancer immunotherapy. Maria is also a medical student at Penn and is interested in oncology and healthcare equity. When she’s not studying, Maria can probably be found running, eating chocolate, or learning something new on the violin.  

Originally from Berkeley, CA, Sam graduated with a BS in biological sciences from the University of Chicago in 2019. He first became enamored with lab research pouring agar plates for Dr. Daniel Portnoy at UC Berkeley, where he later researched how the bacterium Listeria monocytogenes induce a virulence program upon sensing nutrients within host cells. Studying pathogens sparked an interest in the host response, so Sam returned to UC Berkeley for two summers under Dr. David Raulet to research how natural killer cells recognize markers of disease. While at UChicago, he studied with Dr. Erin Adams how the affinity of T cell receptors for self-antigens shapes the development of thymocytes. After graduation, Sam returned to the Raulet Lab to develop approaches of reducing the immunogenicity of CRISPR-Cas9 gene therapy. At Penn, Sam will strive to integrate learning medicine with high-dimensional analyses of human immunity against pathogens. Off campus, Sam enjoys baking crusty sourdough, stewing legumes, collecting psych rock records, and trying to finish novels in time for book club.

Rachel received her BS in biochemistry from Miami University in 2018. During her undergraduate career, she studied the structure of a bacteriophage membrane protein and helped develop novel methods of studying membrane protein structure under the supervision of Dr. Gary Lorigan. After graduation, she became a research assistant at Cincinnati Children’s Hospital in Dr. Lee Grimes’ lab, focusing on myelopoiesis. Rachel’s main project involved understanding the role of the transcription factor Gfi-1 in severe congenital neutropenia with a focus on the transcriptional landscape. Her broad research interests include host-pathogen interactions, adaptive immunity to infectious diseases, and T-cell biology. Eventually, she hopes her research will help decrease infectious disease burden in low-income regions of the world. Outside of the lab, Rachel is an avid traveler, having been to about 35 countries. Locally, she is always on the lookout for the best brunch spot, hiking trail, or IPA in the city.

Isaiah received his BS in Microbiology and Spanish from the University of Wisconsin (UW)-Madison in 2016.  After graduating, he remained at UW-Madison for two years working as a research technician in the laboratory of Dr. Yoshihiro Kawaoka studying Ebola virus.  More specifically, using serum samples collected from both survivors of the virus and those with whom they came in close contact, his project sought to better understand the cellular and molecular mechanisms required to develop immunity to infection.  In 2018, he was awarded a position as a Post-baccalaureate Fellow at the National Institutes of Health in the laboratory of Dr. John O’Shea.  Here, he is studying Natural Killer (NK) cells, an innate lymphocyte critical for defense against viral infection and cancer.  The goal of his project is to understand how Interleukin-18, a proinflammatory cytokine, impacts the NK cell epigenome and how that subsequently affects NK cell effector function in terms of cytotoxicity and Interferon-gamma expression.  His current research interests include better understanding the relationship between the immune system and the microbiome, and how pathologies can potentially develop when their communication pathways are disrupted.  Outside of research, Isaiah enjoys weightlifting, singing, and reading fantasy/science-fiction novels.

William was born and raised in San Sebastian, Puerto Rico. He received his BS in Industrial Microbiology from the University of Puerto Rico at Mayaguez. During his time as an undergraduate, he worked in an evolutionary and population genetics lab under Dr. Juan C. Martinez-Cruzado, studying the principal variants, genomic regions and haplotypes affecting resistance or susceptibility to diabetic nephropathy in Puerto Rico. His summer research experiences while an undergraduate sparked his interest in the molecular mechanisms that regulate immune response. His research interests include non-coding RNA biology, inflammation and immunometabolism. In his free time, he enjoys reading a good book, martial arts, eating and going to the beach with friends and family.

Jeff received his BS in Biology from Rider University in 2019. During his undergraduate, he worked with Dr. James Riggs studying B cell biology and ovarian cancer. After graduating in May 2019, Jeff moved to Philadelphia and began working with Dr. Michael Abt at the University of Pennsylvania as a research specialist. Here he worked on various projects including characterization of the host immune response to C. difficile, a challenging nosocomial infection. His research interests include adaptive immunity, immune memory, and mucosal immunology. In his spare time, Jeff can be found biking or running, pipetting in his sleep, and (covid pending) exploring Philadelphia in search of good nachos and IPAs.

Stefan received his BS in Agriculture & Natural Resources from the University of Delaware in 2012. As an undergraduate, he worked in a lab studying Marek’s disease virus. More recently, he’s been working in the field of CAR T cell therapy examining mechanisms of expansion, persistence, and efficacy in hematologic malignancies. This work has brought him down the path of studying epigenetic and transcriptional regulators of T cell fate and function. He is looking forward to better understanding the role of these epigenetic and transcriptional networks in controlling T cell function with hopes to apply these findings to the fields of immune checkpoint blockade and adoptive cellular therapies. Beyond work in the lab, Stefan enjoys roaming around all the different parts of the city by bike to looking for unique photography opportunities, as well as new places to eat, and explore.

Zachary was born and raised in Upstate New York and received a BS in Biochemistry from Syracuse University in 2017. Zachary decided to leave the northeast and move across the country to work as a research technician in the lab of Dr. Juliana Idoyaga at Stanford. As a member of a dendritic cell biology lab, he worked to characterize a novel dendritic cell population termed the transitional dendritic cell. Zachary’s interest in immunology was sparked under Dr. Idoyaga’s mentorship and has since flourished as he has been gradually exposed to a broad range of immunological concepts. Continuing his studies in immunology, Zachary would like to remain within the realm of innate immunity with interests in metabolism and cancer therapeutics. Outside of lab, Zachary enjoys experimenting in the kitchen, checking out local breweries, and the emotional rollercoaster that is a round of weekend golf. 

Bruktawit obtained her bachelor's degrees in Health Sciences and Spanish from DePaul University. Upon graduating, she joined Dr. Evan Stubbs’s laboratory at the Hines V.A. where she worked with Dr. Kelly Langert to elucidate the protective effects of locally administered Lovastatin encapsulating nanoparticles in Experimental Autoimmune Neuritis. She later joined Dr. Clifford Lane’s laboratory as an NIH postbaccalaureate fellow where she worked on two projects: 1st: Under the mentorship of Dr. Marta Catalfamo, she discovered that combination rhIL-15+Avelumab immunotherapy enhances HIV-specific CD8 T cell functionality. 2nd: She was mentored and worked with Drs. Hiromi Imamichi and Kanal Singh on a longitudinal study of “defective” HIV proviruses in a cohort of chronically HIV-infected patients with the aim of characterizing their changes over time and evaluating their role in HIV-associated pathogenesis. Her research interests lie in immunotherapy and vaccine development against infectious diseases. She enjoys writing, volunteering, and learning about different cultures. 

Emma received a BA in biological sciences from Wellesley College in 2017. Emma has research experience in the laboratory as well as clinical veterinary research experience. In the McNiel Laboratory at Tufts Medical and Veterinary Schools, she studied canine models for human gastric cancer; at the Animal Medical Center in NYC, Emma worked on a clinical immunotherapy trial under the guidance of Dr. Ann Hohenhaus; and her undergraduate thesis investigated the mechanism of action of novel pancreatic chemotherapeutics. Most recently, Emma worked in the Antczak Laboratory, an equine immunology lab at Cornell University’s Baker Institute for Animal Health, where her research focused on improving an equine herpes vaccine. It was there that Emma discovered her passion for horses. In her free time, Emma loves cooking, playing flute, running, bonsai, and spending time with friends, family, and her two senior cats. She has also worked as a professional cake decorator. Emma is thrilled to be pursuing immunology at Penn, where she hopes to study novel immunotherapies.

Rachel received her BS in biochemistry at Union College in 2018. Following graduation, she joined Dr. Peter Sages lab at the Brigham and Women’s Hospital/Harvard Medical School. As a research technician, she investigated the role(s) that TFR cells have on TFH and B cells in the germinal center reaction.  More recently, she has been investigating the role of different cytokine producing TFH cells and how they change depending on context and timing of an immune response. This immunology research has sparked her interest in autoimmunity and hopes to further her research in this area. Outside of lab, Rachel likes to paint, do puzzles, enjoy the outdoors, and spend time with friend and family. 

Julia received her BS in Molecular and Cellular Biology from Stanford in 2018. Her undergraduate thesis in Steven Artandi’s lab centered around understanding the molecular mechanism through which mutant Nucleophosmin1 promotes leukemogenesis. After graduating she worked as a research associate for 3T Biosciences, a cancer immunotherapy start-up based on research from Stanford’s Garcia Lab that focuses on developing TCR based therapies for solid tumors. Her role in identifying novel self-antigen targets for orphan TCRs and establishing TCR cross-reactivity profiles fostered an interest in better understanding the regulation of antigen recognition and activation in T cells. While still fascinated with the immune-oncology space, Julia hopes to explore the role of T cell-based therapies in autoimmunity. Outside of the lab, Julia enjoys biking, rock climbing, and rock music --playing 70s/90s rock on guitar with a questionable amount of skill but a lot of Heart.

Originally from Morelia, Michoacán, Mexico, Montse graduated from the University of Texas at El Paso with a B.S. in Cellular and Molecular Biochemistry in 2019. During her undergraduate training, she was part of the BUILDing SCHOLARS Program, which facilitated the opportunity to conduct research during her summers at various institutions, including the University of New Mexico Health Sciences Center, Baylor College of Medicine, and the University of Rochester. As an undergraduate, she worked under the mentorship of Dr. Laura O’Dell where she completed an undergraduate thesis studying how nicotine withdrawal produces sex-dependent changes in nicotinic acetylcholine receptors in the interpeduncular nucleus. She hopes to combine her interest in the brain and immunology by studying neuro-immune and host-pathogen interactions and sex differences. Montse is excited to join IGG and to eventually become the first Dr. Arreguin in her family. Outside of the lab, Montse enjoys reading, cooking, and attending concerts.

Originally from the Bay Area, Casey received his BS and MS in Molecular, Cellular, and Developmental Biology from Yale University in 2017. During his time in New Haven, he worked in the lab of Kevin O’Connor studying tolerance checkpoints and autoantibody binding in neurologic autoimmune diseases. At Penn, he hopes to continue to explore his passion for pathogenic antibodies and their origins and integrate his interest with clinical applications. In his free time or when procrastinating, Casey enjoys playing board games or video games on his Switch, and he tries his best to wear pink on Wednesdays, because “[o]n Wednesdays, we wear pink.”

Awards
2019 Blavatnik Family Foundation Fellowship
2016 Howard Hughes Medical Institute Medical Research Fellowship

Publications
Radens CM, Blake D, Jewell P, Barash Y, Lynch KW. Meta-Analysis of Transcriptomic Variation in T cell Populations Reveals both Variable and Consistent Signatures of Gene Expression and Splicing. RNA. 2020

Wang, S.*, Campos, J.*, Gallotta, M., Gong, M., Crain, C., Naik, E., Coffman, R. L., & Guiducci, C. (2016). Intratumoral injection of a CpG oligonucleotide reverts resistance to PD-1 blockade by expanding multifunctional CD8+ T cells. Proceedings of the National Academy of Sciences of the United States of America, 113(46), E7240–E7249. (*Co-first authors)

Project Description: Normally bronchus associated lymphoid tissue (BALT) formation is induced by inflammation, but in mice lacking IKKα in lymphatic endothelial cells, BALTs form spontaneously. I aim to elucidate the mechanism of spontaneous BALT formation and determine their impact on immunity.

Awards
2019 National Science Foundation Graduate Research Fellowship

Publications
1.  Finck, Amanda, and Rong Fan. "Single-Cell Cytokine Analysis to Characterize CAR-T Cell Activation." Cell Reprogramming for Immunotherapy. (2020): 67-81.
2.  Deng, Yanxiang, Amanda Finck, and Rong Fan. "Single-cell omics analyses enabled by microchip technologies." Annual review of biomedical engineering 21 (2019): 365-393.

Awards
2020 National Science Foundation Graduate Research Fellowship

Publications
1.  Çuburu N, Khan S, Thompson CD, et al. Adenovirus vector-based prime-boost vaccination via heterologous routes induces cervicovaginal CD8+ T cell responses against HPV16 oncoproteins. Int J Cancer. 2018
2.  Çuburu N, Kim R, Guittard GC, et al. A prime-pull-amplify vaccination strategy to maximize induction of circulating and genital-resident intraepithelial CD8+ memory T Cells. J Immunol. 2019
3.  Kapralov A, Yang Q, Dar H et al. Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death. Nat Chem Biol. 2020

Publications
Ex vivo induction of regulatory T cells from conventional CD4+ T cells is sensitive to substrate rigidity: https://onlinelibrary.wiley.com/doi/full/10.1002/jbm.a.36489

Awards
American Heart Association Predoctoral Fellowship

Publications
1.  Trefoil factor 3 positively associates with IL-25 in patients with Chronic Rhinosinusitis (medRxiv, 2020) *preprint
2.   Adventitial Stromal Cells Define Group 2 Innate Lymphoid Cell Tissue Niches (Immunity, 2019)
3.   Isolation and Identification of Group 2 Innate Lymphoid Cells in Settings of Type 2 Inflammation (Methods in Molecular Biology, 2018)
4.   MicroRNAs 24 and 27 Suppress Allergic Inflammation and Target a Network of Regulators of T Helper 2 Cell-Associated Cytokine Production (Immunity, 2016)

Awards
2017-2018 NCI Cancer Research Training Award

Awards
2020 National Science Foundation Graduate Research Fellowship, Honorable Mention

Publications
Vázquez Marrero VR, Berríos Piñero CA, De Dios Rodríguez LM, Stelzer T, López-Mejías V. (2019) In the Context of Polymorphism: Accurate Measurement and Validation of Solubility Data. Crystal Growth & Design 19(7): 4101-4108

Awards
2020 National Science Foundation Graduate Research Fellowship
2020 Ford Foundation Fellowship, Honorable Mention