Immunology Graduate Group
Recognizing the need to create an environment where researchers could be adequately trained in the multifaceted aspects of immunobiology, Penn became the first medical school to establish a separate degree-granting PhD program in Immunology. The faculty of the Immunology Graduate Group (IGG) are drawn from eight different units of the University of Pennsylvania, encompassing a broad spectrum of research interests: the College of Arts and Sciences; the School of Medicine; the Hospital of the University of Pennsylvania; The Children's Hospital of Philadelphia; the School of Dental Medicine; the School of Veterinary Medicine; The Wistar Institute; and The Abramson Family Cancer Research Institute.
The IGG has also established a partnership with the National Institutes of Health in Bethesda, MD. The partnership brings to the IGG the extraordinary resources and scientific expertise present at the NIH, one of the largest and most renowned biomedical research centers in the world. Students have the opportunity to interact with NIH faculty in a variety of ways, including conducting a lab rotation or thesis work at the NIH. This cross-departmental and institutional organization fosters a unique collaborative environment that allows students to develop research projects combining the expertise of multiple faculty members.
At present, there are approximately 120 faculty members in Penn’s Immunology Graduate Group, encompassing a broad spectrum of research studies. Faculty research includes studies on the development and regulation of the immune system, host-pathogen interactions, the fundamental molecular and cellular biology of the immune system, structural studies of immunologically relevant molecules and translational immunology. Research results are being utilized in both experimental models and clinical trials attempting to fight diseases.
PhD student Claudia Arevalo and the Hensley Lab in a new PNAS paper: "Original antigenic sin priming of influenza virus hemagglutinin stalk antibodies" | Jul 07
Their work shows that heterosubtypic influenza virus infections recall HA stalk antibody responses first established by childhood influenza virus infections.
Student Jennifer Wu and the Wherry, Betts, Hensley, and Cherry Labs present results from deep immune profiling of COVID-19 patients | Jul 16
Penn Medicine researchers studying immune responses of 125 hospitalized #COVID19 patients identified three distinct “Immunotypes,” work that could inform which therapeutic interventions may be most useful in specific patients.