Thesis Title

Provost Postdoctoral Fellow, Children's Hospital of Philadelphia

2025

“IL-27 and the regulation of HSPC development during toxoplasmosis”

“The role of dendritic cells in the generation of CD8+ T cell responses during Cryptosporidium infection”

"Epithelial cell-intrinsic regulation of food antigen-dependent eosinophilic esophagitis"

“Forebrain organoids reveal neuronal capacity to elicit protective antiviral responses”

“Regulation of lung innate immune cell phenotype and function by dietary lipids”

“The impact of prior immunity on B cell responses to viral antigens”

“Mitochondrial NDUFA4 is a functional switch controlling tumor-associated macrophages and tumor immunity”

“Loss of lymphatic IKKα disrupts lung immune homeostasis, drives BALT formation, and protects against influenza”

“Cross-compartment immunology
of pediatric neuroinflammatory
disease”

“Untangling the adjuvanticity of mRNA vaccines: Nucleoside-modified mRNA and lipid nanoparticles cooperate to drive T follicular helper cell responses”

“Asymmetric Cell Division as a Mechanism of Fate Induction in Genetically Engineered T Cells”

“Elucidating Genome Topology Regulation of Antigen Receptor Diversification”

2024

“Building order from disorder: An unstructured domain of TCF-1
preserves T cell lineage fidelity"

2024

“Early-life exposures to specific
commensal microbes train the immune
system and prevent type 1 diabetes”

"Host-Microbe Inheritance: How commensals
and immunity influence cutaneous
phenotypes transgenerationally”

“Lupus is characterized by altered
CD4+ T cell chromatin accessibility”

“Regulation of human cell death
responses to Yersinia infection”

“Cellular targets and modes of
action for proteasome inhibitors in
the B-cell lineage”

“Sensory neurons initiate Tuft
cell-dependent sinonasal allergic
inflammation via substance P”

“Single-cell NAD(H) levels predict clonal
lymphocyte expansion dynamics"

“Notch in the niche: How stromal
notch ligands regulate T cell
development and differentiation
in secondary lymphoid tissue”

“Metabolomic alterations
during acute and post-acute
viral infections”

"The Role of Alternative Splicing and Alternative Polyadenylation in Regulating Activated T cell Biology"

"Ferroptosis of tumor neutrophils causes immune suppression in cancer"

"Overcoming The Chromatin Barrier: A Hematopoietic Pioneer Transcription Factor Paves the Way For Site-Specific ATP-Dependent Nucleosome Remodeling"

Sarah Maddux

"Akkermansia muciniphila modulates early life immune development"

"Immune checkpoint mediated oversight of regulatory T cells at homeostasis and during infection"

"Coping with latent infection in the central nervous system"

"Liver macrophages in pancreatic cancer metastasis"

"In vitro modeling of CD8 T cell exhaustion uncovers novel transcriptional regulator Bhlhe40"

"Chasing a beta life: Role of the ubiquitin ligase FBXW7β isoform in B-lymphopoiesis and leukemia"

"Of Mice, Ferrets and Men: From original antigenic sin to a new universal influenza virus vaccine candidate."

"The Role of Long Noncoding RNAs in Innate Antiviral Immunity"

"Integration of Single Cell Transcriptomics and Epigenomics to Identify New Regulators of T Cell Development and Function"

"A Subpopulation of Lipogenic Brown Adipocytes Drives Thermogenic Memory"

"Understanding the Role of IL-1 Family Cytokines IL-18 and IL-33 in Protective and Pathological Responses to Toxoplasma Gondii"

"Antigen Specific CD4+ T Cell Responses Against a Gastrointestinal Nematode"

Associate Director of Scientific Affairs, PRIME Education 

"Immune Modulation at the Maternal-Fetal Interface Regulates Perinatal Outcomes"

"Identifying and Targeting Mechanisms of Immune Cell Activation in iMCD-TAFRO"

"Vaccine Mediated Immunity to Malaria"

"Lymphocyte Egress Signal Sphingosine-1-Phosphate Promotes ERM-Guided, BLEB-Based Migration"

"Vb Recombination Signal Sequences Mediate Monoallelic and Monogenic TCRb Gene Assembly: Implications for the TCRb Repertoire and Allelic Exclusion in Health and Disease"

"Regulation of Selection and Central Tolerance by the N-Terminal Region of RAG1"

"Thymic Stromal Lymphopoietin Induces Adipose Loss through Sebum Hypersecretion"

"Tumor-Derived Retinoic Acid Regulates Intratumoral Monocyte Differentiation to Promote Immune Suppression"

"Immune Dysregulation in Pancreatic Cancer"

"Transcriptional Landscapes in Lymphocyte Development and Differentiation: TCF-1 Enforces Epigenetic Identity in Developing T cells and T-BET Resolves Functionally Distinct Memory B Cells"

"Cellular Localization of Inflammatory Signaling as a Determinant of Tumor-Immune Biology"

"Type 1 Conventional Dendritic Cells are Systemically Dysregulated Early in Pancreatic Carcinogenesis'

"Genome Integrity and Cell Division: Next-Generation Answers to Enduring Questions"

"T-BET Expressing B Cells With Distinct Residency and Functional Characteristics Give Rise to Plasma Cells"

"The Regulation and Function of Major Histocompatibility Complex II on Lung Type II Alveolar Cells"

"Structure-Function Analysis of BET Proteins in Transcription"

Otolaryngology/Head & Neck Surgery Resident, Northwell Health

"Leucine Rich Repeat IG-Domain Containing NOGO Interacting Protein 3 (LINGO3) is a Novel Regulator of Mucosal Homeostasis"

"Contribution of Non-Classical Antigen Presentation to CD4+ T Cells During Orthopoxvirus Infection"

"The HMG Transcription Factor TOX Induces a Transcriptional and Epigenetic Program of CD8+ T Cell Exhaustion in Chronic Infection and Cancer"

"Hepatocytes direct the formation of a pro-metastatic niche in the liver"

Resident - Pathology, Johns Hopkins Hospital

"A Mendelian Disease of Autoimmunity Reveals GIMAP5 as a Novel Member of the Ragulator Complex"

"Epigenetic Control of Innate Lymphoid Cell Homeostasis and Development"

"The Immunomodulatory Functions of Diacylglycerol Kinase Zeta on Type 2 Immune Responses"

"Regulation of Effective B Cell Responses to Chronic Infection"

"Engineering CD8+ T Cells to Overcome Death Signaling Within The Tumor Microenvironment"