Perelman School of Medicine at the University of Pennsylvania

Nathanson Lab


Cancer Genetics/Genomics Post-doctoral Positions Available
University of Pennsylvania, Philadelphia PA

The Nathanson laboratory invites applications for Post-Doctoral positions at the Perelman School of Medicine, University of Pennsylvania.  We focus on cutting-edge translational research in cancer genetics, both in the inherited and somatic genetics of cancer (example publications include Garman et al., Cell Rep 2107; Rebbeck et al., Hum Mut 2018; Maxwell et al., Nat Comm 2017; Slavin et al., NPJ Breast Cancer 2017).  Expertise and interest in both wet bench studies and bioinformatics is preferred, however applicants with only expertise in bioinformatics would be welcome. The laboratory is highly collaborative and investigates several cancers, among which are hereditary breast cancer (due to BRCA1/2 and non-BRCA1/2 mutations), melanoma, testicular germ cell tumors, and neuroendocrine tumors.  Applications for postdoctoral positions are invited across all areas of research, all of which are funded by multiple NIH grants and foundation funding.  Potential projects include research on the inherited and somatic genetics of breast cancer, including identification of novel susceptibility genes, characterization of moderate penetrance genes, and somatic studies of breast and other cancers in BRCA1/2 mutation carriers (with bulk and single cell RNA/DNA sequencing, and immunophenotyping), with the opportunity to perform correlative studies in relationship to therapeutic response, both targeted and immunotherapies. Other example projects could be focused on the intersection of cancer genetics (inherited/somatic) and response to immunomodulatory therapies, and post-GWA studies in testicular germ cell tumors.  The laboratory is located with the Institute for Immunology at Penn, and there are multiple opportunities for local collaboration.  Applicants also will have the opportunity to engage in collaborative efforts at the national and international stage.

A strong background in human genetics, cancer genetics and genomics, genetic epidemiology, and/or computational biology, bioinformatics preferred.  Highly motivated individuals with a recent PhD and a strong track record of research as evidenced by publications; excellent written and verbal communication; expertise in bioinformatics DNA analysis software; strong attention to detail, multi-tasking; and a willingness to learn new technologies are encouraged to apply. The applicant should have published in top tier journals and demonstrated an ability to successfully complete projects independently.  Candidates are expected to establish independent research projects, and to generate high impact publications, providing outstanding opportunity for further career development in academia.

Please send a cover letter, including why you are interested in this position, a CV and name of three references by email to Dr. Nathanson.