Perelman School of Medicine at the University of Pennsylvania

Oathes Lab

Oathes Lab Personnel


Principal Investigator

Desmond Oathes, PhD

Desmond Oathes, PhD
Assistant Professor, Lab Director, CNDS Associate Director

Dr. Oathes is a licensed Clinical Psychologist (CA) and Assistant Professor in the Department of Psychiatry at the University of Pennsylvania. He has been on the Penn faculty since 2015 before which he was an Instructor in the Psychiatry Department at Stanford University.  (CV)



Postdoctoral Fellows

Romain Duprat, PhD

Romain Duprat, PhD

I received my PhD in Medicine and Health Sciences from Gent University, Belgium. During my doctoral studies, I focused on the use of neuromodulation techniques to treat major depressive disorders. More specifically, I developed and tested a new stimulation protocol (accelerated iTBS) in treatment-resistant depressed patients. I also investigated the role of the reward system and anhedonia in the response to stimulation in the healthy and depressed state, at the behavioral and neuroimaging level (fMRI). Thanks to many collaborations and to my background in Molecular and Cellular Biology, I acquired a translational knowledge of rTMS neuromechanisms of action in the human brain and in animal models.


Kristin Brethel-Haurwitz, PhD

Kristin Brethel-Haurwitz, PhD

Dr. Brethel-Haurwitz is a Postdoctoral Researcher in the Kable Lab at Penn, and her current research focuses on the brain bases of empathy and social cognition in selfish decision-making. She is collaborating with the Oathes Lab on a project examining modulation of social preferences via TMS.


Kenji Kobayashi, PhD

Kenji Kobayashi, PhD

Kenji is a post-doctoral researcher in Joe Kable's lab. He received his PhD in Neuroscience from University of California, Berkeley, and did postdoctoral training at Columbia University before moving to Penn. His past research focused on neurocognitive mechanisms of uncertainty reduction and information seeking in the service of value-based decision making, using behavioral modeling, fMRI, and EEG. In collaboration with Oathes lab, he is currently working on a project stimulating TPJ to modulate perspective-taking behavior.


Jennifer Goldschmied, PhD

Jennifer Goldschmied, PhD

Jen will be starting a project (with Phil Gehrman) studying slow wave sleep, depression, and cortico-cortico paired-associative TMS.  Bio coming soon. See: https://www.researchgate.net/profile/Jennifer_Goldschmied



Clinician/Scientists

Mario Cristancho, MD

Mario Cristancho, MD
Assistant Professor of Clinical Psychiatry, Penn TMS Treatment Program Director

Dr.Cristancho’s clinical focus is in the area of mood disorders particularly treatment resistant depression. He specializes in the use of psychopharmacology and neuromodulation interventions including Electroconvulsive Therapy (ECT), Transcranial Magnetic Stimulation (TMS), Vagus Nerve Stimulation (VNS), and Deep Brain Stimulation (DBS).  His clinical and research activities include the assessment and treatment of mood and anxiety disorders, optimization of existing treatments, and development of new therapeutic options.  He has co-authored over 20 manuscripts and projects including peer reviewed papers and book chapters in mood disorders and neuromodulation. For the Oathes Lab, Dr. Cristancho provides oversight and training of personnel delivering repetitive TMS as well as provides coverage for scans utilizing rTMS as a research device.



Research Assistants / Clinical Coordinators

Morgan Scully, BA

Morgan Scully, BA
 mscull@mail.med.upenn.edu
 215-746-6751

Morgan graduated with a psychology major from Villanova University. She plans to attend a Masters in Education graduate program in Fall 2019 but will still be working in the lab part time. In the Oathes lab, she does clinical screens of patients, administers TMS and records MRI and psychophysiological data.


Hannah Long, BA

Hannah Long, BA
 hanlong@mail.med.upenn.edu

I graduated from the University of Miami with departmental honors in Neuroscience and a minor in Computer Science. In the past I have primarily studied resting state variability and connectivity in correlation with various behavioral measures. I hope to one day attend a graduate program, and look forward to exploring the effects of TMS in various clinical populations in the Oathes lab.


Gabriela Bagdon (Vogeley)

Gabriela Bagdon (Vogeley)

Gabriela graduated from Princeton University in 2018 with a bachelor's degree in neuroscience. Her primary interest is treatment of abnormal brain functioning, and she plans to pursue a medical degree with the ultimate goal of practicing neurology.


Almaris Figueroa

Almaris Figueroa

Alma graduated from the University of Puerto Rico-Rio Piedras Campus in 2017 with a B.S. in Molecular Cell Biology. During her post-baccalaureate at the NIH, she studied the neuronal pathways involved in anxiety-related behaviors. Alma is interested in studying the neural architecture of psychiatric illnesses and intends to pursue a PhD in Clinical Psychology.


Joe Deluisi

Joe Deluisi

Joe graduated from Northeastern University with a B.S. in Behavioral Neuroscience. He is a coordinator for the Network Control TMS fMRI study. In the future, Joe plans to study cognitive neuroscience as a graduate student.


Ximo Liang

Ximo Liang
Junior Data Analyst

Ximo graduated from Drexel University with an M.S. in Business Analytics. His responsibilities include MRI image processing, analysis and related data management. Ximo plans to employ methodologies of data science and machine learning in the neuroscience field.


Heather Robinson

Heather Robinson

Heather graduated from Haverford College with a bachelor’s degree in Psychology and a minor in Neuroscience. Her primary interest is in the neural correlates of cognitive biases underlying psychopathology. Heather hopes to pursue a PhD in Cognitive Neuroscience.


Monica (Mengqun) Lyu

Monica (Mengqun) Lyu
 Mengqun.Lyu@pennmedicine.upenn.edu

I graduated from the University of California, San Diego with an Honors in Psychology and a minor in Cognitive Science. I am really excited to join the Oathes lab to explore the neural mechanisms that are involved in people with mood disorders. In the future, I wish to study Clinical Psychology in graduate school.



Collaborators

Yvette Sheline, MD

Yvette Sheline, MD
McClure Professor of Psychiatry and Director of the Center for Neuromodulation in Depression and Stress

As Professor of Psychiatry, Radiology and Neurology and Director, Center for Neuromodulation and Stress at the University of Pennsylvania, I have over two decades of experience conducting innovative clinical neuroscience research that bridges the fields of neuroimaging, translational research and clinical treatment. Recent projects include how inflammation may moderate antidepressant outcomes, how ‘anxious-misery’ across disorders relates to resting fMRI signals, and the neural predictors of outcome to computerized cognitive behavioral psychotherapy.


Kristin Linn, PhD

Kristin Linn, PhD
Assistant Professor of Biostatistics (Penn)

Dr. Linn's methodological research focuses on imaging and the design and analysis of sequentially randomized trials. She works on several CNDS projects, and along with other members of the Oathes lab is interested in characterizing brain network responses to TMS in fMRI recordings.


Yong Fan, PhD

Yong Fan, PhD
Assistant Professor of Radiology

Dr. Fan has a broad background in medical image analysis and pattern recognition, with specific training in applied mathematics, statistics, and machine learning. WDr. Fan is co-PI on an R01 with Dr. Oathes using deep learning to decode working memory targets from multi-modal MRI data then to use real-time rTMS/fMRI to optimize stimulation for achieving working memory enhancement.


Ted Satterthwaite, MD

Ted Satterthwaite, MD
Assistant Professor of Psychiatry (PENN)

Dr. Sattherthwaite uses multi-modal neuroimaging to characterize abnormalities in neuropsychiatric disorders as well as to describe brain/behavior changes in neurodevelopment.  He collaborates with the Oathes lab on DSI derived network control predictors of TMS/fMRI (w/ Dani Bassett). We also have a donor funded project with the Kable lab zapping TPJ to improve 'mentalizing' based decisions.


Joe Kable, PhD

Joe Kable, PhD
Associate Professor of Psychology (Penn)

Dr. Kable is the Baird Term Associate Professor of Psychology at the University of Pennsylvania. Research in his lab is concerned with the neurobiology of decision-making. He collaborates with the Oathes lab on projects related to social judgment and reward learning with TMS including a donor funded project with Ted Satterthwaite.


Mark Elliott, PhD

Mark Elliott, PhD
Associate Director CMROI, Department of Radiology (Penn)

Dr. Elliott is a biophysicist with expertise in MRI acquisition and analysis, particularly in the field of functional neuroimaging. In the Oathes lab, Dr. Elliott contributes to triggering TMS in the scanner, testing image quality, and designing MRI sequences to capture neural responses to TMS.


(Russell) Taki Shinohara, PhD

(Russell) Taki Shinohara, PhD
Assistant Professor of Biostatistics (Penn)

Dr. Shinohara's methodological research spans several concentrations, including causal inference, survival analysis, imaging and large data sets, and general inference problems. He works on several CNDS projects and with the Oathes lab is working on analysis strategies to characterize brain network responses to TMS in fMRI recordings.


Dani Bassett, PhD

Dani Bassett, PhD
Associate Professor of Bioengineering (PENN)

Dr. Bassett is a leader in applying concepts from network control theory to studies of the brain which is the basis for a collaboration with Drs. Oathes and Satterthwaite (R01 supplement + Multi-PI RF1).


Michael Platt, PhD

Michael Platt, PhD
PIK Professor (PENN)

Dr. Platt applies mathematical-economic principles to understand primate neurobiology and decision making. Through a collaboration funded by the Penn Translational Neuroscience Initiative, he collaborates on a project with the Oathes lab et al (PIs Platt/Sheline ; coIs Oathes/Kable/Gold) investigating human/NHP overlaps in brain/behavior responses to TMS.



Alumni

Ben Rosenberg

Ben Rosenberg
Graduate student, UCLA Psychology

Ben helped to start the lab at Penn and was instrumental in setting up many of the scan, psychophysiological and behavioral protocols that include TMS in the Oathes lab.  He will continue to collaborate on publishing data by remote as he continues his Ph.D. Clinical Psychology program at UCLA.


Matt Flounders

Matt Flounders
Junior Data Analyst

Matt graduated from the University of Pittsburgh in 2015 with a B.S. in Neuroscience. During a fellowship at NIH, he studied perceptual awareness and top-down processing using MEG and fMRI. His research interests include multi-modal imaging of the healthy and psychiatric brain. Matt is now enrolled in medical school starting in Fall 2019 (PCOM).


Jared Zimmerman

Jared Zimmerman
Graduate Student, Penn

Jared did a rotation followed by one year doing TMS/fMRI data analysis in the lab. He is currently on an auditory neuroscience fellowship and working in Roy Hamilton's lab at Penn (Neurology).


Golkoo Hosseini, MD, MSED

Golkoo Hosseini, MD, MSED
TMS Clinical Service and Scientist
 golh@mail.med.upenn.edu

Golkoo received her M.D. in 2010. After graduation, she worked as a general physician for almost three years. This experience enabled her to confirm and establish her commitment to the field of mental health. Since coming to the U.S. in 2014 she sought to expand her knowledge regarding human development and mental health and earned an M.S.Ed from the department of Applied Psychology and Human Development, University of Pennsylvania. Recently, she was the coordinator of the TMS Treatment Program, Department of Psychiatry, University of Pennsylvania, part time clinical research coordinator at Mood and Anxiety Disorders Treatment and Research Program. In the Oathes Lab, Golkoo provided rTMS treatment to patients and provides physician coverage for rTMS delivered in the MRI. She is now completing her residency in Psychiatry at Penn.