Perelman School of Medicine at the University of Pennsylvania

Immunology & Immunotherapy for Pancreatic Cancer

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Agenda

Thursday, April 11, 2019

5:00 pm                 Registration and cocktails

5:30 pm                 Welcome from Penn’s Pancreatic Cancer Research Center
                                Ben Z. Stanger, MD, PhD // Gastroenterology // PENN ​

Keynote Presentation

5:40 pm                 Cancer Immunotherapy – Vive la révolution
                                Robert H. Vonderheide, MD, DPhil // Director, Abramson Cancer Center // PENN

6:30 pm                 Dinner

Friday, April 12, 2019

7:45 am                 Registration and Continental Breakfast 

8:25 am
                 Welcome and Introduction

                                Ben Z. Stanger, MD, PhD // Gastroenterology // PENN

SESSION 1: PDA IMMUNOTHERAPY 2019 - What do we know?

8:30 am                 Patient Experience I: Navigating pancreatic cancer treatment
                                Diann Boyd, BSN, MSN, OCN // Nurse Navigator // PENN

8:45 am                 Where We Stand: Standard of care options for pancreatic cancer
                                Thomas B. Karasic, MD // Hematology Oncology// PENN

9:10 am                 Immunotherapy for PDA – What do we know and what are we missing?
                                Gregory L. Beatty, MD, PhD // Medical Oncology // PENN

9:35 am                 Immunotherapy clinical trials: checkpoint inhibitors and beyond 
                   
             Mark H. O’Hara, MD // Hematology Oncology // PENN

10:00 am                BREAK

SESSION 2: TRANSLATING LABORATORY DISCOVERIES INTO INTERVENTIONS

10:20 am                 Clinical Translation of Targeting Pancreatic Cancer Microenvironment 
                                  Andrea Wang-Gillam, MD, PhD // Medical Oncology // Washington University
                                  School of Medicine

10:45 am                 Targeting the pancreatic tumor microenvironment to improve response to therapy
                                  David G. DeNardo, PhD // Molecular Oncology // Washington University School
                                  of Medicine

11:10 am                 T cell immunity to pancreatic cancer - is it possible, 
                   
              and how do we get there?   
                   
               Stephanie K. Dougan, PhD // Cancer Immunology and Virology // Dana-Faber 
                                 Cancer Institute

11:35 am                 Overcoming immunotherapy resistance in pancreatic cancer using
                   
              preclinical
                   
               Ingunn Stromnes, PhD //Microbiology and Immunology // University of
                                  Minnesota Medical School

12:00 pm                 Abstract Presentation

12:15 pm                 Lunch and poster session 

SESSION 3: PRACTICE-CHANGING DEVELOPMENTS

1:45 pm                  Immunotherapy and DNA Repair: A meaningful intersection? 
                   
              Kim A. Reiss-Binder, MD // Hematology Oncology// PENN

2:10 pm                 Immunotoxin therapy for pancreatic cancer
                   
             Christine Campo Alewine, MD, PhD // Molecular Biology // 
                                National Cancer Institute

2:35 pm                 CAR-T cells: promises and challenges for pancreatic cancer
                   
             Carl H. June, MD // Immunotherapies // PENN

3:00 pm                 Managing toxicities associated with immunotherapy
                   
             Moderator: Mark H. O’Hara, MD // Hematology Oncology // PENN

                                Panel Members to be announced 

3:45 pm                 Adjourn