ADVOCATE (GPA and MPA)

Full Name: A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Safety and Efficacy of CCX168 (Avacopan) in Patients with Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis Treated Concomitantly with Rituximab or Cyclophosphamide/Azathioprine
Study Dates: 2017-2020
NCT #: NCT02994927
Study Findings: This study demonstrated that the study drug CCX168 (avacopan) can effectively improve remission rates, kidney function, and overall quality of life of patients with ANCA-associated vasculitis, compared with standard therapy with steroids.