A Pragmatic, Open-Label, Two-Stage, Pilot Study of Effectiveness of Immunomodulatory Medications for Patients with Relapsing Polychondritis (PROSPECT)

The purpose of this study is to understand the effectiveness of commonly used medications for treating RP in adults with mild to moderately active RP. Participants have regular clinic visits and assessments with their rheumatologist such as physical exams and bloodwork. Questionnaires are done for research purposes.

There are 2 stages of the study - each involving up to 4 in-person visits over 6 months. Participants come to the Perelman Center or Penn Medicine University City (PMUC). Visits are also done by video or phone. If during the 6 months, participants do not respond to study treatment or have a relapse, they will have the option enter stage 2 of the study and start a new medicine.

ClinicalTrials.gov ID: NCT06941376

Study Duration: 6 to 12 months

Disease(s): Relapsing Polychondritis (RP)