Breakfast, Lunch, and Light Reception included. Sponsored by the Physiological Society of Philadelphia and the Pennsylvania Muscle Institute.
Symposium Schedule 10/16/2023
8:30am – 9:00am: Registration check-in, Posters Setup, Breakfast & Coffee (table seating available in BRB 14th Floor Lounge)
9:00am – 9:15am: Welcome - E. Michael Ostap, PhD, Director, Pennsylvania Muscle Institute, Professor of Physiology & Jonathan A. Epstein, MD, Executive Vice Dean and Chief Scientific Officer, Perelman School of Medicine at the University of Pennsylvania; Senior Vice President and Chief Scientific Officer, University of Pennsylvania Health System; William Wikoff Smith Professor of Medicine (Cardiology) and Cell and Developmental Biology
9:15am – 9:30am: 50 Years of Progress at the PMI - E. Michael Ostap, PhD
9:30am – 10:15am: Andrew Somlyo Honorary Lecture:
Jennifer Lippincott-Schwartz, PhD - Senior Group Leader and Head of Janelia's 4D Cellular Physiology, HHMI Janelia Research Campus:
“How the cytoskeleton controls the structure and dynamics of the endoplasmic reticulum”
10:15am – 10:30am:
Adam Fenton (Holzbaur and Jongens Labs, Penn):
“FMRP-associated protein synthesis locally determines mitochondrial organization in neurons”
10:30am – 11:00am: Coffee Break, Posters
11:00am – 11:45am:Andrew Somlyo Honorary Lecture:
Andrew P. Carter, PhD - Investigator, MRC Laboratory of Molecular Biology:
“Cargo transport by dynein/dynactin”
11:45am – 12:15pm:
Roberto Dominguez, PhD - William Maul Measey Presidential Professor of Physiology (Penn):
“Structural-Functional Mechanisms Controlling Actin Filament Barbed and Pointed End Dynamics”
12:30pm – 1:30pm: Lunch, Posters (table seating available in BRB 14th Floor Lounge)
1:30pm – 1:45pm:
Xingyuan Fang (Svitkina Lab, Penn):
“Mechanism of branched actin assembly in microtubule- and APC-dependent manner”
1:45pm – 2:00pm:
Qing Tang, PhD (Lakadamyali Lab, Penn):
“Insight into cytoskeleton sorting from microtubule detyrosination”
2:00pm – 2:30pm:
Hansell H. Stedman, MD - Professor of Surgery (Penn):
“Gene Therapy for Inherited Muscle Disease: A Glimpse of the Summit Ridge from Everest Base Camp”
2:30pm – 3:00pm: Coffee Break, Posters
3:00pm – 3:15pm:
Jennifer Petrosino, PhD (Prosser Lab, Penn):
“The Hitchhiker’s Guide to the Myocyte: Active transport of tRNAs facilitates distributed protein synthesis”
3:15pm – 3:45pm:
Sharlene M. Day, MD - Presidential Associate Professor of Medicine & Director, Translational Research, Div. of Cardiovascular Medicine (Penn):
“Mechanisms of Myosin Binding Protein C Mutations in Hypertrophic Cardiomyopathy”
3:45pm – 4:00pm: Introduction: Jean and Joseph Sanger Lecture in Muscle Biology - E. Michael Ostap, PhD
4:00pm – 4:45pm: Jean and Joseph Sanger Lecture in Muscle Biology:
James A. Spudich, PhD - Douglass M. and Nola Leishman Professor of Cardiovascular Disease, Stanford University:
“Myosin, the exquisite nanomachine: From basic science to biotech to medicines”
Public Parking at Penn (closest to BRB IS 3600 Civic Center Blvd.)
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