PMI Annual Symposium 2023

October 16, 2023
BRB Gaulton Auditorium & Lobby, Biomedical Research Building (BRB II/III) - 421 Curie Blvd., Philadelphia 19104


Registration closed October 9, 2023.


 FULL Program 





PMI Annual Retreat & Symposium 2023

"Celebrating 50 Years of Muscle, Motors, and the Cytoskeleton" 


Monday, October 16, 2023

BRB Gaulton Auditorium & Lobby,

Biomedical Research Building (BRB II/III)

421 Curie Blvd., Philadelphia, PA 19104 (map)


8:30-5:45pm (in-person event only)

Breakfast, Lunch, and Light Reception included. Sponsored by the Physiological Society of Philadelphia and the Pennsylvania Muscle Institute.

Symposium Schedule 10/16/2023

  • 8:30am – 9:00am:       Registration check-in, Posters Setup, Breakfast & Coffee                                                   (table seating available in BRB 14th Floor Lounge)
  • 9:00am – 9:15am:       Welcome -  E. Michael Ostap, PhD, Director, Pennsylvania Muscle Institute, Professor of Physiology & Jonathan A. Epstein, MD, Executive Vice Dean and Chief Scientific Officer, Perelman School of Medicine at the University of Pennsylvania; Senior Vice President and Chief Scientific Officer, University of Pennsylvania Health System; William Wikoff Smith Professor of Medicine (Cardiology) and Cell and Developmental Biology
  • 9:15am – 9:30am:       50  Years of Progress at the PMI - E. Michael Ostap, PhD
  • 9:30am – 10:15am:      Andrew Somlyo Honorary Lecture: 
    • Jennifer Lippincott-Schwartz, PhD - Senior Group Leader and Head of Janelia's 4D Cellular Physiology, HHMI Janelia Research Campus: 
      • “How the cytoskeleton controls the structure and dynamics of the endoplasmic reticulum”
  • 10:15am – 10:30am:     
    • Adam Fenton (Holzbaur and Jongens Labs, Penn): 
      • “FMRP-associated protein synthesis locally determines mitochondrial organization in neurons” 
  • 10:30am – 11:00am:       Coffee Break, Posters
  • 11:00am – 11:45am:       Andrew Somlyo Honorary Lecture: 
    • Andrew P. Carter, PhD - Investigator, MRC Laboratory of Molecular Biology: 
      • “Cargo transport by dynein/dynactin” 
  • 11:45am – 12:15pm:      
    • Roberto Dominguez, PhD - William Maul Measey Presidential Professor of Physiology (Penn):
      • “Structural-Functional Mechanisms Controlling Actin Filament Barbed and Pointed End Dynamics” 
  • 12:30pm – 1:30pm:      Lunch, Posters (table seating available in BRB 14th Floor Lounge)
  • 1:30pm – 1:45pm:       
    • Xingyuan Fang (Svitkina Lab, Penn): 
      • “Mechanism of branched actin assembly in microtubule- and APC-dependent manner” 
  • 1:45pm – 2:00pm:       
    • Qing Tang, PhD (Lakadamyali Lab, Penn):
      • “Insight into cytoskeleton sorting from microtubule detyrosination” 
  • 2:00pm – 2:30pm:       
    • Hansell H. Stedman, MD - Professor of Surgery (Penn):
      • “Gene Therapy for Inherited Muscle Disease: A Glimpse of the Summit Ridge from Everest Base Camp” 
  • 2:30pm – 3:00pm:       Coffee Break, Posters
  • 3:00pm – 3:15pm:      
    • Jennifer Petrosino, PhD (Prosser Lab, Penn):
      • “The Hitchhiker’s Guide to the Myocyte: Active transport of tRNAs facilitates distributed protein synthesis” 
  • 3:15pm – 3:45pm:      
    • Sharlene M. Day, MD - Presidential Associate Professor of Medicine & Director, Translational Research, Div. of Cardiovascular Medicine (Penn):
      • “Mechanisms of Myosin Binding Protein C Mutations in Hypertrophic Cardiomyopathy”
  • 3:45pm – 4:00pm:        Introduction:  Jean and Joseph Sanger Lecture in Muscle Biology - E. Michael Ostap, PhD
  • 4:00pm – 4:45pm:        Jean and Joseph Sanger Lecture in Muscle Biology:  
    • James A. Spudich, PhD - Douglass M. and Nola Leishman Professor of Cardiovascular Disease, Stanford University:
      • “Myosin, the exquisite nanomachine: From basic science to biotech to medicines
  • 4:45pm – 5:45pm:        Reception, Posters
  • 5:45pm – 6:00pm:        Farewell, Posters take-down

Downloads & LINKS: