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August 13, 2024
Toxoplasma gondii rhoptry discharge factor 3 is essential for invasion and microtubule-associated vesicle biogenesis
Yi-Wei Chang, Ph.D.
Ben Chaabene R, Martinez M, Bonavoglia A, Maco B, Chang YW, Lentini G, Soldati-Favre D. Toxoplasma gondii rhoptry discharge factor 3 is essential for invasion and microtubule-associated vesicle biogenesis. PLoS Biol. 2024 Aug 13;22(8):e3002745. doi: 10.1371/journal.pbio.3002745. Epub ahead of print. PMID: 39137211.
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August 9, 2024
Regulation of and challenges in targeting NAD+ metabolism
Joseph A. Baur, Ph.D.
Migaud ME, Ziegler M, Baur JA. Regulation of and challenges in targeting NAD+ metabolism. Nat Rev Mol Cell Biol. 2024 Jul 18. doi: 10.1038/s41580-024-00752-w. Epub ahead of print. PMID: 39026037.
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August 1, 2024
Visualization and Quantification of Organelle Axonal Transport in Cultured Neurons
Erika L. F. Holzbaur, Ph.D.
Aiken J, Holzbaur ELF. Visualization and Quantification of Organelle Axonal Transport in Cultured Neurons. Methods Mol Biol. 2024;2831:219-234. doi: 10.1007/978-1-0716-3969-6_15. PMID: 39134853.
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August 1, 2024
Free energy calculations for membrane morphological transformations and insights to physical biology and oncology
Paul A. Janmey, Ph.D., Wei Guo, Ph.D.
Parihar K, Ko SH, Bradley R, Taylor P, Ramakrishnan N, Baumgart T, Guo W, Weaver VM, Janmey PA, Radhakrishnan R. Free energy calculations for membrane morphological transformations and insights to physical biology and oncology. Methods Enzymol. 2024;701:359-386. doi: 10.1016/bs.mie.2024.03.028. Epub 2024 Apr 14. PMID: 39025576; PMCID: PMC11258396.
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July 25, 2024
Translating metabolic and cardiovascular research into effective treatments: What's next?
Zolt Arany, M.D.
Zierath JR, van der Velden J, Javaheri A, Rosenzweig A, Muoio DM, Mulvihill EE, Martino TA, Rasheed A, Chen XW, Arany ZP. Translating metabolic and cardiovascular research into effective treatments: What's next? Cell. 2024 Jul 25;187(15):3880-3884. doi: 10.1016/j.cell.2024.06.034. PMID: 39059364.
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July 24, 2024
An egg-sabotaging mechanism drives non-Mendelian transmission in mice
Michael Lampson, Ph.D.
Clark FE, Greenberg NL, Silva DMZA, Trimm E, Skinner M, Walton RZ, Rosin LF, Lampson MA, Akera T. An egg-sabotaging mechanism drives non-Mendelian transmission in mice. Curr Biol. 2024 Jul 24:S0960-9822(24)00901-1. doi: 10.1016/j.cub.2024.07.001. Epub ahead of print. PMID: 39067449.
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July 23, 2024
Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo
Joseph A. Baur, Ph.D.
Nanga RPR, Wiers CE, Elliott MA, Wilson NE, Liu F, Cao Q, Swago S, Jacobs PS, Armbruster R, Reddy D, Baur JA, Witschey WR, Detre JA, Reddy R. Acute nicotinamide riboside supplementation increases human cerebral NAD+ levels in vivo. Magn Reson Med. 2024 Jul 23. doi: 10.1002/mrm.30227. Epub ahead of print. PMID: 39044608.
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July 19, 2024
Characterization and structural basis for the brightness of mCLIFY: a novel monomeric and circularly permuted bright yellow fluorescent protein
Yale E. Goldman, M.D., Ph.D
Shweta H, Gupta K, Zhou Y, Cui X, Li S, Lu Z, Goldman YE, Dantzig JA. Characterization and structural basis for the brightness of mCLIFY: a novel monomeric and circularly permuted bright yellow fluorescent protein. Res Sq [Preprint]. 2024 Jul 19:rs.3.rs-4638282. doi: 10.21203/rs.3.rs-4638282/v1. PMID: 39070629; PMCID: PMC11276004.
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July 19, 2024
The infrapatellar fat pad in inflammaging, knee joint health, and osteoarthritis
Patrick Seale, Ph.D.
Wang MG, Seale P, Furman D. The infrapatellar fat pad in inflammaging, knee joint health, and osteoarthritis. NPJ Aging. 2024 Jul 15;10(1):34. doi: 10.1038/s41514-024-00159-z. PMID: 39009582; PMCID: PMC11250832.
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July 18, 2024
NAD+ precursors prolong survival and improve cardiac phenotypes in a mouse model of Friedreich's Ataxia
Joseph A. Baur, Ph.D.
Perry CE, Halawani SM, Mukherjee S, Ngaba LV, Lieu M, Lee WD, Davis JG, Adzika GK, Bebenek AN, Bazianos DD, Chen B, Mercado-Ayon E, Flatley LP, Suryawanshi AP, Ho I, Rabinowitz JD, Serai SD, Biko DM, Tamaroff J, DeDio A, Wade K, Lin KY, Livingston DJ, McCormack SE, Lynch DR, Baur JA. NAD+ precursors prolong survival and improve cardiac phenotypes in a mouse model of Friedreich's Ataxia. JCI Insight. 2024 Jul 18;9(16):e177152. doi: 10.1172/jci.insight.177152. PMID: 39171530; PMCID: PMC11343603.
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