Perelman School of Medicine at the University of Pennsylvania

Penn Institute for Immunology

Jerilynn Radcliffe

faculty photo
Professor CE of Pediatrics
Department: Pediatrics

Contact information
The Children's Hospital of Philadelphia
Division of Developmental and Behavioral Pediatrics
3400 Civic Center Blvd
CHOP North 1461
Philadelphia, PA 19104
Office: 215 590-7446
Fax: 215 590-3020
Bryn Mawr College, Cum Laude, 1970.

Diploma, Assumption Montessori Training Center, 1971.
MSEd (Psychological Services in Education)
University of Pennsylvania Graduate School of Education, 1975.
Ph.D. (Psychology)
University of Pennsylvania, 1981.
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Description of Research Expertise

I have participated in many research initiatives at CHOP in the areas of cognitive and psychosocial outcomes of treatment for chronic pediatric illnesses, originally pediatric brain tumor and sickle cell disease. I remain active in national multisite research efforts aimed at understanding the cognitive and behavioral effects of environmental metals upon children’s development. The Treatment of Lead-exposed Children’s Study, launched in 1993 as an NIH-sponsored multisite randomized controlled trial of the effects of succimer, an oral chelating agent, on mild to moderate levels of lead exposure in infants and toddlers, has studied the effects of lead, mercury and cadmium upon children’s behavior and development. These efforts continue.

I have also participated, and now direct, The MOM Program, a home visiting program for mothers living in poverty, designed to empower mothers to seek services to enhance their children’s development. The MOM Program grew out of the Philadelphia TLC Study, as program staff became more aware of the barriers faced by mothers living in poverty when they tried to seek services on behalf of their children. This study was initially led by Dr. Donald F. Schwarz, who is now the Deputy Mayor for Health and Opportunity for the City of Philadelphia. The MOM Program has become a flagship project within the City of Philadelphia for addressing the needs of mothers and children living in poverty within a greatly expanded City- and State-funded initiative. Results from The MOM Program have been presented nationally. The MOM Program is yet another interdisciplinary effort that exemplifies the contributions of pediatric psychology, in that I worked closely and collaboratively with colleagues in both pediatrics and nursing in the design, implementation, and evaluation of the program.

A final area of active research is in the area of HIV. I became involved in HIV clinical work early in the epidemic, when I was asked to conduct developmental evaluations on newly-diagnosed children. This gave rise to my overseeing the conduct of yearly cognitive evaluations of perinatally-exposed children. In 2005, I was asked to become part of a newly organized program, the Adolescent HIV Initiative, a clinic designed to provide clinical services to behaviorally infected adolescents with HIV. Here, I have designed the mental health program offered in the program and have conducted clinical research on service provision and clinical needs of the youth served. I participate in Adolescent Trials Network-funded studies of the neurocognitive effects of HAART and of the effectiveness of a cognitive-behavioral intervention to treat drug and alcohol abuse. In addition, I am engaged in research among African American adolescents and young men who have sex with men and who live with HIV, examining the effects of trauma, stigma, and spirituality on sexual health risk, towards developing more effective secondary prevention interventions with HIV-positive youth. .

Description of Clinical Expertise

Child and adolescent neurocognition
Psychosocial issues of adolescents and young adults living with HIV
Autism Diagnostic Observational Schedules

Selected Publications

Thomas, NH, Xanthopoulos, MS, Kim, JY, Giordani, B, Hodges, E, Chervin, RD, Paruthi, S, Rosen, CL, Arens, R, Radcliffe, J. & Marcus, CL.: ). Effects of adenotonsillectomy on parent-reported behavior in children with obstructive sleep apnea. Sleep 40(4), 2017.

Cielo, CM, Taylor JA, Vossough A, Radcliffe J, Thomas A, Bradford R, Lioy J, Tapia IE, Assadsangabi R, Shults J, Marcus CL.: Evolution of obstructive sleep apnea in infants with cleft palate and micrognathi. J Clinical Sleep Medicine 12(7): 979-987, 2016.

Busch, D.R., Lynch, J.M., Winters, M.E., McCarthy, A.L., Newland, J.J., Ko, T., Cornaglia M.A., Radcliffe, J., McDonough, J.M., Samuel, J., Matthews, E., Xiao, R., Yodh, A.G., Marcus, C.L., Licht, D.J., Tapia, E.E.: Cerebral blood flow response to hypercapnia in children with obstructive sleep apnea syndrome. Sleep 39 (1): 209-16, 2016.

Silverstein, F.S., Slomine, B.S., Christensen, J., Holubkov, R., Page, K., Dean, J.M., Molder, F.W.: Functional outcome trajectories after out-of-hospital pediatric cardiac arrest. Critical Care Medicine 44(12), 2016.

Nichols, S.L., Bethel, J., Kapogiannis, B.G., Li, T., Woods, S.P., Patton, E.D., Ren, W., Thornton, S.E., Major-Wilson, H.O., Puga, A.M., Sleasman, J.W., Rudy, B.J., Wilson, C.M., Garvie, P.A.: Antretroviral treatment initiation does not differentially alter neurocognitive functioning over time in youth with behaviorally acquired HIV. J Neurovirology 22(2): 218-30, 2016.

Meert, K.L., Telfored, R., Holubkov, R., Slomine, B.S., Christensen, J.R., Dean, J.M., Moler, F.W.: Therapeutic Hypothermia after Pediatric Cardiac Arrest (THAPCA) Trial Investigators: Pediatric out-of-hospital cardiac arrest characteristics and their association with survival and neurobehavioral outcome. Pediatric Critical Care Medicine 17(12): e543-e550, 2016.

Sun, LS, Guohua, L, Miller, TLK, Salorio, C., Byrne, MW, Bellinger, DC, Ing, CH, Park, R, Radcliffe, J., Hays, SR, DiMaggio, CJ, Cooper, TJ, Rauh, V, Maxwell, LG, Youn, A, &7 McGowan, FX.: Association between a single general anesthetic exposure before age 36 months and neurocognitive outcomes in later childhood. J American Medical Association 315(21): 1-10, 2016.

Radcliffe J, Schall J, Weiss A, Bragg H, Ford E, Berenbaum S, Rogan W, & Stallings VA.: Does soy formula alter gendered play in toddlers? 2015 Biennial Meeting of the Society for Research in Child Development, Philadelphia, Pennsylvania March 2015.

Lord K, Radcliffe J, Gallagher PR, Adzick S, Stanley CA, De Leon DD.: High Risk of Diabetes and Neurobehavioral Deficits in Individuals with Surgically Treated Hyperinsulinism. 97th Annual Meeting of the Endocrine Society, San Diego, California March 2015.

Moler, F.W., Silverstein, F.S.,Holubkov, R., Slomine, B.S., Christensen, J.R., Nadkarni, V.M., Meert, K.L.,Clark, A.E., Browning, B., Pemberton, V.L., Page, K., Shankaran, S., Hutchison, J.S., Newth, C.J., Bennett, K.S.,Berger, J.T.,Toopjian, A., Pineda, J.A.,Koch, J.D., Schlein, C.L.,Dalton, H.J.,Ofori-Amanfo, G., et al: Therapeutic hypothermia after out-of-hospital cardiac arrest in children. New England Journal of Medicine 14; 372(20): 1898-9908, 2015.

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Last updated: 06/20/2017
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