Cesar de la Fuente, Ph.D.

faculty photo
Presidential Assistant Professor
Secondary Appointments in Bioengineering and Microbiology, Perelman School of Medicine, University of Pennsylvania
Department: Psychiatry

Contact information
Robert Wood Johnson Pavilion / 3610 Hamilton Walk
Lab: Room 302C
Office: Room 303C
Philadelphia, PA 19104
Office: 2157466083
M.Sc. (Biotechnology)
University of Leon, 2009.
Ph.D. (Microbiology & Immunology)
University of British Columbia, 2014.
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Selected Publications

Porto, W.F., Irazazabal, L., Alves, E., Ribeiro, S.M., Pires, A.S., Fernserseifer, I., Haney, E.F., Humblot, V., Hancock, R.E.W., Liao, L.M., Ladram, A., Lu, T.K., de la Fuente-Núñez, C.#, Franco, O.L.#: In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design. Nature Communications 9(1): 1490, Apr 2018 Notes: doi: 10.1038/s41467-018-03746-3. # indicates corresponding authorship.

Torres MDT, Pedron CN, Higashikuni Y, Kramer RM, Cardoso MH, Oshiro KGN, Franco OL, Silva Junior PI, Silva FD, Oliveira Junior VX#, Lu TK#, de la Fuente-Nunez C#: Structure-function-guided exploration of the antimicrobial peptide polybia-CP identifies activity determinants and generates synthetic therapeutic candidates Nature Commun Biol 1(221), Dec 2018 Notes: doi: 10.1038/s42003-018-0224-2. # indicates corresponding authorship.

Pane, K., Cafaro, V., Avitabile, A., Vollaro, A., De Gregorio, E., Catania, M.R., Maro, A. D., Bosoo, A., Gallo, G., Zanfardino, A., Varcamonti, M., Lu, T.K., Pizzo, E., di Donato, A., Lu, T.K., de la Fuente-Núñez, C.#, Notomista, E.#: Identification of novel cryptic multifunctional antimicrobial peptides from the human stomach enabled by a computational-experimental platform. ACS Synthetic Biology 7(9): 2105-2115, Sep 2018 Notes: doi: 10.1021/acssynbio.8b00084. Epub 2018 Aug 20. # indicates corresponding authorship.

Torres MDT, Sothiselvam S, Lu TK, de la Fuente-Nunez C#: Peptide Design Principles for Antimicrobial Applications. J Mol Biol Jan 2019 Notes: pii: S0022-2836(18)31289-0. doi: 10.1016/j.jmb.2018.12.015. # indicates corresponding authorship.

de la Fuente-Núñez, C.#, Meneguetti, B.T., Franco, O.L., Lu, T.K.#: Neuromicrobiology: how microbes influence the brain. ACS Chemical Neuroscience 9(2): 141-150, 2018 Notes: doi: 10.1021/acschemneuro.7b00373. # indicates corresponding authorship.

Torres Marcelo Der Torossian, de la Fuente-Nunez Cesar: Toward computer-made artificial antibiotics. Current opinion in microbiology 51: 30-38, Oct 2019.

Der Torossian Torres Marcelo, de la Fuente-Nunez Cesar: Reprogramming biological peptides to combat infectious diseases. Chemical communications (Cambridge, England) 55(100): 15020-15032, Dec 2019.

Inda María Eugenia, Broset Esther, Lu Timothy K, de la Fuente-Nunez Cesar: Emerging Frontiers in Microbiome Engineering. Trends in immunology 40(10): 952-973, Oct 2019.

Yehl Kevin, Lemire Sébastien, Yang Andrew C, Ando Hiroki, Mimee Mark, Torres Marcelo Der Torossian, de la Fuente-Nunez Cesar, Lu Timothy K: Engineering Phage Host-Range and Suppressing Bacterial Resistance through Phage Tail Fiber Mutagenesis. Cell 179(2): 459-469.e9, Oct 2019.

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Last updated: 09/12/2022
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