faculty photo

Garret A. FitzGerald

Robert L. McNeil, Jr., Professor in Translational Medicine and Therapeutics
Department: Medicine

Contact information
Department of Pharmacology
153 Johnson Pavilion
3620 Hamilton Walk
Philadelphia, PA 19104-6084
Office: (215) 898-1185
Fax: (215) 573-9135
Education
MB, BCh (Honors, First Place)
University College, Dublin, Ireland, 1974.
Diploma (Statistics)
Trinity College, Dublin, Ireland, 1977.
M.Sc. (Statistics)
University of London, 1979.
M.D.
University College, Dublin, 1980.
D.Sc. (Hon Causa)
University of Edinburgh, UK, 2004.
D.Sc. (Hon Causa)
National University of Ireland (150th Anniversary), Dublin, Ireland, 2004.
M.D. (Hon Causa)
Johann Wolfganag Goethe University of Frankfurt, Germany, 2007.
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Description of CVI Expertise

CVI Program Unit(s):
Lipid / Atherosclerosis / CAD / ACS / Prevention
Thrombosis / Hemostasis

CVI Research Description:
Role of eicosanoids in cardiovascular biology.
Role of peripheral clocks in metabolism, inflammation and cardiovascular function.

Selected Publications

Kunieda T, Minamino T, Miura K, Katsuno T, Tateno K, Miyauchi H, Kaneko S, Bradfield CA, FitzGerald GA, Komuro I: Reduced nitric oxide causes age-associated impairment of circadian rhythmicity. Circulation Res 102: 607-614, 2008.

Wang M, Stubbe J, Lee E, Song W, Ricciotti E, Rader DJ, Lawson JA, Pure E, FitzGerald GA: Microsomal prostaglandin E synthase-1 deletion suppresses oxidative stress and angiotensin II-induced abdominal aortic aneurysm formation. Circulation 117: 1302-1309, 2008.

Song W-L, Wang M, Ricciotti E, Fries S, Yu Y, Grosser T, Reilly M, Lawson JA, FitzGerald GA: Tetranor PGDM, an abundant urinary metabolite reflects biosynthesis of prostaglandin D2 in mice and humans. J Biol Chem 283: 1179-1188, 2008.

Reilly DF, Curtis AM, Cheng Y, Westgate EJ, Rudic RD, Paschos G, Morris J, Ouyang M, Thomas SA, FitzGerald GA: Peripheral circadian clock rhythmicity is retained in the absence of adrenergic signaling. Arterioscl Thromb Vasc Biol 28: 121-126, 2008.

FitzGerald GA: Translational therapeutics at the platelet vascular interface (Introduction). Arterioscl Thromb Vasc Biol 28: S3-S4, 2008.

FitzGerald GA: Translational therapeutics at the platelet vascular interface (Summary). Arterioscl Thromb Vasc Biol 28: S51-S52, 2008.

Chen M, Boilard E, Nigrovic PA, Clark P, Xu D, FitzGerald GA, Audoly LP, Lee DM: Predominance of cyclooxygenase 1 over cyclooxygenase 2 in the generation of proinflammatory prostaglandins in autoantibody-driven K/BxN serum-transfer arthritis. Arthritis & Rheumatism 58: 1354-1365, 2008.

Fitzgerald GA: Drugs, industry, and academia. Science 320: 1563, 2008.

Wang M, Song, W-L, Cheng Y, Fitzgerald GA: Microsomal prostaglandin E synthase-1 inhibition in cardiovascular inflammatory disease [Review] J Intern Med 263: 500-505, 2008.

FitzGerald GA: Guest authorship, mortality reporting, and integrity in rofecoxib studies [Comment] JAMA 300: 900-901; author reply 904-905, 2008.

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Last updated: 06/24/2009
The Trustees of the University of Pennsylvania
 

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