Transforming Kidney Transplants
Transforming Kidney Transplants: Pioneering Advances for a Healthier Tomorrow
Research in kidney transplantation aims to innovate in transplant science to increase access to transplantation and significantly enhance graft survival rates and patient well-being post-transplant. It is a continually evolving field that focuses on various aspects to improve patient outcomes, understand the biology of transplant rejection, and enhance the overall transplantation process.
Our kidney transplantation research mainly focuses on expanding access to kidney transplantation, testing novel approaches to reduce complications of transplantation and improving patient understanding of transplantation and complications.
- James F. Markmann, MD, PhD
- Amanda K. Leonberg-Yoo, MD
- Vishnu Potluri, MD, MPH
- Srijan Tandukar, MD
- Matthew H. Levine, MD, PhD
- Peter L. Abt, MD
- Emily Vail, MD, MSc
- Ronald Fairbairn Parsons, MD
Expanding access to kidney transplantation through
- Optimizing paired kidney donation (Amanda K. Leonberg-Yoo)
- Using geospatial scientific methods to find inefficiencies in allocation (Vishnu Potluri, Emily Vail)
- Identify the effect of organ allocation policies on disparities in access to transplant (Vishnu Potluri, Srijan Tandukar)
- Utilize geospatial epidemiology to optimize organ recovery and reduce unnecessary organ discard (Vishnu Potluri)
Testing novel approaches to reduce complications of transplantation through
- Technologies and approaches that enhance medication adherence (Roy D. Bloom, Sandra Amaral, Srijan Tandukar)
- Better matching on eplets and epitopes between organs and recipients (CHOP team)
- Revealing mechanisms of ischemia-reperfusion injury that can be disrupted (Matthew H. Levine)
- Understanding immunological mechanisms that might enable graft tolerance (James F. Markmann)
- Accurate risk stratification of kidney transplant candidates by their cardiovascular comorbidities to realize optimal longevity matching (Srijan Tandukar)
- Understanding the risk of APOL1 gene on kidney transplant outcomes (Srijan Tandukar)