Amanda K. Leonberg-Yoo, MD
Associate Professor of Clinical Medicine (Renal-Electrolyte and Hypertension)
Program Director Nephrology Fellowship, University of Pennsylvania, Renal-Electrolyte and Hypertension Division
Medical Director Living Kidney Donor Program, Penn Transplant Institute, University of Pennsylvania Health System
Department: Medicine
Contact information
Department of Medicine
Renal Electrolyte and Hypertension Division
3737 Market Street
12th Floor, Suite 1225
Philadelphia, PA 19104
Renal Electrolyte and Hypertension Division
3737 Market Street
12th Floor, Suite 1225
Philadelphia, PA 19104
Links
Penn Kidney Medicine Dialysis Care
Penn's Renal-Electrolyte and Hypertension Division
Penn Presbyterian Medical Center
Penn Kidney Medicine Dialysis Care
Penn's Renal-Electrolyte and Hypertension Division
Penn Presbyterian Medical Center
Education
BS
John Carroll University, Cleveland, Ohio, 2005.
MD
Creighton University, Omaha, Nebraska, 2010.
MS (Clinical and Translational Research)
Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, MA, 2016.
Permanent linkBS
John Carroll University, Cleveland, Ohio, 2005.
MD
Creighton University, Omaha, Nebraska, 2010.
MS (Clinical and Translational Research)
Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, MA, 2016.
Description of Clinical Expertise
1. Living Kidney Donation2. Hemodialysis management
3. Chronic Kidney Disease management
Description of Research Expertise
1. Medical Education - Involvement in all aspects of medical training at Penn School of Medicine and Penn Graduate Medical Education. Areas of expertise include novel curriculum development including enhanced multidisciplinary teaching in palliative care, critical care, and glomerular diseases. Additional efforts have focused on increasing minority trainee representation within nephrology.2. Kidney living donor evaluation and outcomes - Expansion of non-directed donation through collaboration with the National Kidney Registry. Quality improvement efforts for more streamlined and donor-centered care approaches, leading to improved donor experience and improved efficiency of living donor evaluation processes.
3. Influence of dietary patterns and CKD management - This area of research includes the association of micronutrient content and clinical outcomes in chronic kidney disease and healthy individuals. She is interested in the clinical outcomes associated with potassium, sodium, and the ratio of these two electrolytes in terms of cardiovascular and kidney disease clinical outcomes and has published in this area.
4. Contrast associated acute kidney injury - Involvement in both scholarly activity and quality improvement of assessment and management of IV contrast nephrotoxicity.
Selected Publications
Wilson C, Thorne A, Kumar V, Bloom RD, Leonberg-Yoo A, Reese PP, Potluri VS.: Underutilization of Preemptive Waitlisting for Prior Living Donors Who Develop ESKD. Kidney360 Aug 2026.Leonberg-Yoo A, Leonberg KE, Abu Gazala S, Hryzak S, Redfield RR 3rd, Parsons RF, Agarwal AK, Delgado MK, Lee D, Trofe J.: Patient-reported Opioid use and Pain Management After Living Kidney Donation. Transplant Direct 12: e1954, May 2026.
Arpali E, Abu-Gazala S, Redfield RR 3rd, Leonberg-Yoo A, Dunn TB.: Transplant center practices that maximize access to living kidney transplantation: the Penn experience. Front Immunol 16: 1700930, Jan 2026.
Reese PP, Tamboli D, Potluri V, Goldberg DS, Venkatakrishnan R, Mussell A, McKenzie SJ, Perez G, Chen L, Mapchan S, Schaubel DE, Leonberg-Yoo A, Krieger JL, Lok B.: An Interactive Virtual Nephrologist to Engage Patients With Advanced CKD About Transplantation. Am J Kidney Dis 2026.
Leonberg-Yoo A, Redfield R, Dunn T, Fleming JN, Fonk J, Hil G, Cooper M: Strategic Innovations to Reduce Disincentives and Increase Living Kidney Donation. Kidney360 7: 397-407, Oct 2025.
Wang LS, Ertmann E, Feldman E, Kossoff M, Lu B, Lin JC, Pishko A, Redfield R, Leonberg-Yoo A, Cuker A.: Utility of Activated Partial Thromboplastin Time Screening in Prospective Living Kidney Donors: A Single Center Cohort Study. Kidney Med 7: 100951, Dec 2024.
Leonberg-Yoo AK, Gilbert SJ.: Teaching Conservative Kidney Management and Other Palliative Care Skills in Nephrology Fellowships. Semin Nephrol 43: 151396, Aug 2023.
Kearney D, Leonberg-Yoo A, Cohen R.: Frequent vascular access thrombosis in a patient with end stage kidney disease on hemodialysis. Semin Dial Aug 28 2023 Notes: doi: 10.1111/sdi.13172. Online ahead of print.
Green A, Rachoin JS, Schorr C, Dellinger P, Casey JD, Park I, Gupta S, Baron RM, Shaefi S, Hunter K, Leaf DE; STOP-COVID Investigators.: Timing of invasive mechanical ventilation and death in critically ill adults with COVID-19: A multicenter cohort study. PLoS One 18: e0285748, Jun 2023.
Sunderraj A, Cho C, Cai X, Gupta S, Mehta R, Isakova T, Leaf DE, Srivastava A; STOP-COVID Investigators.: Modulation of the Association Between Age and Death by Risk Factor Burden in Critically Ill Patients With COVID-19. Crit Care Explor 4: e0755, Aug 2022.