Michael Silverman, MD, PhD
Assistant Professor of Pediatrics (Infectious Diseases)
Department: Pediatrics
Graduate Group Affiliations
Contact information
Children's Hospital of Philadelphia
Division of Infectious Diseases
3615 Civic Center Blvd
Philadelphia, PA 19104
Division of Infectious Diseases
3615 Civic Center Blvd
Philadelphia, PA 19104
Email:
silvermam1@email.chop.edu
silvermam1@email.chop.edu
Education:
BS (Biology)
Cornell University, 1998.
MD, PhD (Medicine and Immunology)
University of Pennsylvania School of Medicine, 2007.
BS (Biology)
Cornell University, 1998.
MD, PhD (Medicine and Immunology)
University of Pennsylvania School of Medicine, 2007.
Post-Graduate Training
Intern, Pediatrics, Boston Children's Hospital , 2007-2008.
Resident, Pediatrics, Boston Children's Hospital, 2008-2010.
Fellow, Infectious Diseases, Boston Children's Hospital, 2010-2013.
Post-Doctoral Fellow, Department of Microbiology and Immunobiology, Harvard Medical School, 2011-2016.
Permanent linkIntern, Pediatrics, Boston Children's Hospital , 2007-2008.
Resident, Pediatrics, Boston Children's Hospital, 2008-2010.
Fellow, Infectious Diseases, Boston Children's Hospital, 2010-2013.
Post-Doctoral Fellow, Department of Microbiology and Immunobiology, Harvard Medical School, 2011-2016.
Description of Clinical Expertise
Immunocompromised patientsDescription of Research Expertise
Microbiome, Immunology, HLA, MHC, antibiotics, intestinal immune system, autoimmune (type I) diabetes, IgA deficiency, Early life immune system developmentSelected Publications
Michael Silverman and Kathryn Knoop: Setting the table for immune tolerance. Science 389(6761): 684-685, August 2025.Shenhav L, Azad M, and Silverman MA.: Human Milk as a Microbial Pacemaker. Cell Host and Microbe 33(6): 762-765, June 2025.
Natalie A Trigg, Simon K Zhou, Jordan C Harris, Madeline N Lamonica, Molly A Nelson, Michael A Silverman, Taku Kambayashi, Colin C Conine: A lack of commensal microbiota influences the male reproductive tract intergenerationally in mice. Reproduction 169(4): e240204, March 2025.
Jean-Bernard Lubin, Paul J. Planet, Michael A. Silverman: Microbial succession at weaning is guided by microbial metabolism of host glycans. bioRxiv Page: doi: 10.1101/2025.02.20.639370, February 2025.
Jean-Bernard Lubin, Paul J. Planet, Michael A. Silverman: Microbial succession at weaning is guided by microbial metabolism of host glycans. Microbiome (in press) 2025.
Siqi Linsey Zhang, Carolyn M McGann, Tereza Duranova, Jonathan Strysko, Andrew P Steenhoff, Alemayehu Gezmu, Britt Nakstad, Tonya Arscott-Mills, One Bayani, Banno Moorad, Nametso Tlhako, Melissa Richard-Greenblatt, Paul J Planet, Susan E Coffin, Michael A Silverman: Maternal and neonatal IgG against Klebsiella pneumoniae are associated with lower risk of neonatal sepsis: a case-control study of hospitalized neonates in Botswana. PLOS Global Public Health 4(12): e0003350, December 2024.
Liat Shenhav, Kelsey Fehr, Myrtha E Reyna, Charisse Petersen, Darlene L Y Dai, Ruixue Dai, Vanessa Breton, Laura Rossi, Marek Smieja, Elinor Simons, Michael A Silverman, Maayan Levy, Lars Bode, Catherine J. Field, Jean S Marshall, Theo J Moraes, Piush J Mandhane, Stuart E Turvey, Padmaja Subbarao, Michael G Surette, Meghan B Azad: Microbial colonization programs are structured by breastfeeding and guide healthy respiratory development. Cell 187(19): 5431-5452, September 2024.
Jean-Bernard Lubin, Michael A Silverman, Paul J Planet: Comparison of gnotobiotic communities reveals milk-adapted metabolic functions and unexpected amino acid metabolism by the pre-weaning microbiome. Gut Microbes 16(1): 2387875, August 2024.
Siqi Linsey Zhang, Carolyn M McGann, Tereza Duranova, Jonathan Strysko, Andrew P Steenhoff, Alemayehu Gezmu, Britt Nakstad, Tonya Arscott-Mills, One Bayani, Banno Moorad, Nametso Tlhako, Melissa Richard-Greenblatt, Paul J Planet, Susan E Coffin, Michael A Silverman: Maternal and neonatal IgG against Klebsiella pneumoniae are associated with broad protection from neonatal sepsis: a case-control study of hospitalized neonates in Botswana. medRxiv Page: doi: 10.1101/2024.05.28.24308042, May 2024.
Jamal Green, John Deschaine, Jean-Bernard Lubin, Julia Flores, Sarah Maddux, Tereza Duranova, Logan Grimes, Paul J. Planet, Laurence C. Eisenlohr, Michael A. Silverman: Early-life exposures to specific commensal microbes prevent type 1 diabetes. bioRxiv Page: doi.org/10.1101/2024.02.15.580579. February 2024.
Contact us
Institute for Diabetes, Obesity and Metabolism
Smilow Center for Translational Research
3400 Civic Center Boulevard, 12th Floor
Philadelphia, PA 19104
Phone: 215-898-0198 | Fax 215-898-5408
Directions
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