faculty photo

Ming-Lin Liu

Research Assistant Professor of Dermatology
Department: Dermatology

Contact information
Department of Dermatology
University of Pennsylvania Health System
Perelman School of Medicine
University of Pennsylvania
2 East. Gates Building, #2021
3600 Spruce Street
Philadelphia, PA 19104
Education:
MD
Tianjin Medical University, 1986.
PhD
University of Helsinki, 2003.
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Description of Research Expertise

1) Cell Death and Inflammation

2) Effects of UVB Exposure on Autoimmune Skin Inflammation and Autoimmune Diseases.

3) Effects of Tobacco Smoking on Autoimmune and Cardiometabolic Diseases.

4) Basic and clinical research regarding the role of immune cell microvesicles and NETosis in Autoimmune Skin Inflammation, Autoimmune and Cardiometabolic Diseases.

5) Basic and clinical research regarding dyslipidemia in Cardiometabolic Diseases and Cardiometabolic Complications of Autoimmune Diseases

Selected Publications

ML Liu, KJ Williams, VP Werth: Microvesicles in Autoimmune Diseases. Advances in Clinical Chemistry (in press) 2016

Chen Y, Li G, Liu Y, Werth VP, Williams KJ, Liu ML.: Translocation of Endogenous Danger Signal HMGB1 from Nucleus to Membrane Microvesicles in Macrophages. Journal of Cellular Physiology. Wiley, 231(11): 2319-26, November 2016

Folkesson M, Li C, Frebelius S, Swedenborg J, Wagsater D, Williams KJ, Eriksson P, Roy J, Liu ML. : Proteolytically Active ADAM10 and ADAM17 Carried on Membrane Microvesicles in Human Abdominal Aortic Aneurysms. Thrombosis and Haemostasis 114(6): 1165-74, November 2015.

Kim DK, Lee J, Kim SR, Choi DS, Yoon YJ, Kim JH, Go G, Nhung D, Hong K, Jang SC, Kim SH, Park KS, Kim OY, Park HT, Seo JH, Aikawa E, Baj-Krzyworzeka M, van Balkom BW, Belting M, Blanc L, Bond V, Bongiovanni A, Borràs FE, Buée L, Buzás EI, Cheng L, Clayton A, Cocucci E, Dela Cruz CS, Desiderio DM, Di Vizio D, Ekström K, Falcon-Perez JM, Gardiner C, Giebel B, Greening DW, Gross JC, Gupta D, Hendrix A, Hill AF, Hill MM, Nolte-'t Hoen E, Hwang DW, Inal J, Jagannadham MV, Jayachandran M, Jee YK, Jørgensen M, Kim KP, Kim YK, Kislinger T, Lässer C, Lee DS, Lee H, van Leeuwen J, Lener T, Liu ML, Lötvall J, Marcilla A, Mathivanan S, Möller A, Morhayim J, Mullier F, Nazarenko I, Nieuwland R, Nunes DN, Pang K, Park J, Patel T, Pocsfalvi G, Del Portillo H, Putz U, Ramirez MI, Rodrigues ML, Roh TY, Royo F, Sahoo S, Schiffelers R, Sharma S, Siljander P, Simpson RJ, Soekmadji C, Stahl P, Stensballe A, Stępień E, Tahara H, Trummer A, Valadi H, Vella LJ, Wai SN, Witwer K, Yáñez-Mó M, Youn H, Zeidler R, Gho YS. : EVpedia: A Community Web Portal for Extracellular Vesicles Research. Bioinformatics 31(6): 933-939, 2015.

Boden G, Cheung P, Salehi S, Homko C, Loveland-Jones C, Jayarajan S, Stein TP, Williams KJ, Liu ML, Barrero CA, Merali S.: Insulin regulates the unfolded protein response (UPR) in human adipose tissue. Diabetes. 63(3): 912-22, Mar 2014 Notes: full publication.

Li C, Liu Y, Yu D, Williams KJ, Liu ML: Novel proteolytic microvesicles released from human macrophages after exposure to tobacco smoke. American Journal of Pathology. 182(5): 1552-62, May 2013 Notes: full publication [published with an associated Commentary by Philip Furmanski in AJP 2013 May, PMID:23499459, and is recommended by Richard Stevens in F1000Prime 2013 May]

Liu ML, Scalia R, Mehta JL, Williams KJ: Cholesterol-induced membrane microvesicles as novel carriers of damage-associated molecular patterns: mechanisms of formation, action, and detoxification. Arteriosclerosis, Thrombosis, and Vascular Biology. 32(9): 2113-21, Sep 2012 Notes:

Liu ML and Williams KJ: potential markers and mediators of endothelial dysfunction- Curr Opin Endocrinol Diabetes Obes. 19(2): 121-7, Apr 2012

Chen K, Liu ML, Schaffer L, Li MZ, Williams KJ: Type 2 diabetes in mice induces hepatic overexpression of sulfatase 2, a novel factor that suppresses uptake of remnant lipoproteins. Hepatology. 52: 1957-1967, 2010.

Li MZ, Yu DM, Williams KJ, Liu ML.: Tobacco Smoke Induces the Generation of Procoagulant Microvesicles from Human Monocytes/Macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology. 30(9): 1818-24, Sep 2010 Notes:

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Last updated: 05/25/2017
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