Description of Research Expertise

Research Interests: Dr Dokras directs the Penn Polyendocrine Metabolic Ovarian Syndrome (formerly known as Polycystic Ovary Syndrome) transdisciplinary clinical and research program.

Keywords: PMOS/PCOS, androgens, metabolic risk, mood disorders, cardiovascular disease

Research Details: An internationally recognized physician-scientist and NIH-funded investigator, Dr Dokras' research has transformed understanding of the long-term health consequences of Polyendocrine Metabolic Ovarian Syndrome (formerly PCOS), one of the most common endocrine disorders affecting ~10% of reproductive age women. Over the past two decades, her work has advanced knowledge of the cardiometabolic, reproductive, and psychological complications of PMOS, with an in depth focus on identifying factors that contribute to cardiovascular disease risk, metabolic dysfunction, infertility, and mental health disorders in women across the lifespan.

Dr. Dokras has led numerous NIH-funded clinical trials and translational research studies that have directly informed evidence-based care for women with PMOS. Her research has informed international clinical guidelines, improve treatment strategies, and highlight the importance of addressing quality of life and mental health alongside reproductive and metabolic outcomes. As a strong patient advocate, she works collaboratively with patient support groups to inform her research priorities.

Description of Clinical Expertise

Dr Dokras directs the Penn Polyendocrine Metabolic Ovarian Syndrome (PMOS, formerly PCOS) Center which offers comprehensive gynecological, reproductive, dermatological, metabolic, nutritional and psychological care to women with PMOS. The PMOS care team has expertise in treating all PMOS symptoms and related conditions using the latest therapies. The Center offers comprehensive care with a personalized treatment plan that addresses individual patient symptoms and needs.

Description of Other Expertise

Innovation
Dr Dokras is the founding Executive Director of the Women’s Health Center for Clinical Innovation (WHCCI) at Penn Medicine a pioneering center dedicated to improving the health and healthcare experience of women through innovation, research, and implementation science. WHCCI brings together multidisciplinary teams of clinicians, researchers, engineers, and healthcare innovators to develop, evaluate, and scale patient-centered solutions that address critical front line challenges in women’s healthcare delivery across the lifespan. Through initiatives in digital health, care delivery redesign, artificial intelligence, remote monitoring, and health equity, the Center accelerates the translation of innovative ideas into real-world clinical practice that are scaled across the health system and nationally.