Damaris Lorenzo, MSc, PhD
Presidential Associate Professor
Department: Cell and Developmental Biology
Graduate Group Affiliations
Contact information
421 Curie Boulevard
Biomedical Research Building 1112
Philadelphia, PA 19104
Biomedical Research Building 1112
Philadelphia, PA 19104
Office: (651) 283-0368
Lab: (215) 898-7886
Lab: (215) 898-7886
Education:
B.S. (Biochemistry (summa cum laude))
University of Havana, 1999.
MSc (Plant Molecular Biology)
University of Havana, 2003.
PhD (Molecular, Cell, Developmental Biology and Genetics)
University of Minnesota, 2009.
B.S. (Biochemistry (summa cum laude))
University of Havana, 1999.
MSc (Plant Molecular Biology)
University of Havana, 2003.
PhD (Molecular, Cell, Developmental Biology and Genetics)
University of Minnesota, 2009.
Post-Graduate Training
Postdoctoral Fellow, HHMI at Duke University, 2009-2015.
Permanent linkPostdoctoral Fellow, HHMI at Duke University, 2009-2015.
Selected Publications
Voos KM, Tzeng J, P Patel, Rubinsky S, Choi HE, Pharr T, Sookram S, Baur JA, Soderblom EJ, Lorenzo DN. : Ankyrin-B modulates mitochondrial fission in skeletal muscle and is required for optimal endurance exercise capacity. Nature Communications 16(1): 7671, August 2025Damaris N. Lorenzo, Reginald J. Edwards, Anastasia L. Slavutsky: Spectrins: molecular organizers and targets of neurological disorders. Nat Rev Neurosci Jan 2023.
Creighton BA, Afriyie S, Ajit D, Casingal CR, Voos KM, Reger J, Burch AM, Dyne E, Bay J, Huang JK, Anton ES, Fu MM, Lorenzo DN.: Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A. Elife 10: e69815, Nov 2021.
Cousin MA, Creighton BA, Breau KA, Spillmann RC, Torti E, Dontu S, Tripathi S, Ajit D, Edwards RJ, Afriyie S, Bay JC, Harper KM, Beltran AA, Munoz LJ, Falcon Rodriguez L, Stankewich MC, Person RE, Si Y, Normand EA, Blevins A, May AS, Bier L, Aggarwal V, Mancini GMS, van Slegtenhorst MA, Cremer K, Becker J, Engels H, Aretz S, MacKenzie JJ, Brilstra E, van Gassen KLI, van Jaarsveld RH, Oegema R, Parsons GM, Mark P, Helbig I, McKeown SE, Stratton R, Cogne B, Isidor B, Cacheiro P, Smedley D, Firth HV, Bierhals T, Kloth K, Weiss D, Fairley C, Shieh JT, Kritzer A, Jayakar P, Kurtz-Nelson E, Bernier RA, Wang T, Eichler EE, van de Laar IMBH, McConkie-Rosell A, McDonald MT, Kemppainen J, Lanpher BC, Schultz-Rogers LE, Gunderson LB, Pichurin PN, Yoon G, Zech M, Jech R, Winkelmann J; Undiagnosed Diseases Network; Genomics England Research Consortium, Beltran AS, Zimmermann MT, Temple B, Moy SS, Klee EW, Tan QK, Lorenzo DN.: Pathogenic SPTBN1 variants cause an autosomal dominant neurodevelopmental syndrome. Nat Genet 2021.
Lorenzo DN.: Cargo hold and delivery: Ankyrins, spectrins, and their functional patterning of neurons. Cytoskeleton (Hoboken) 2020.
Lorenzo DN, Badea A, Zhou R, Mohler PJ, Zhuang X, Bennett V.: βII-spectrin promotes mouse brain connectivity through stabilizing axonal plasma membranes and enabling axonal organelle transport. Proc Natl Acad Sci U S A 116: 15686-15695, Jul 2019.
Lorenzo DN, Bennett V.: Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency. Proc Natl Acad Sci U S A 114: 12743-12748, Nov 2017.
Contact us
Institute for Diabetes, Obesity and Metabolism
Smilow Center for Translational Research
3400 Civic Center Boulevard, 12th Floor
Philadelphia, PA 19104
Phone: 215-898-0198 | Fax 215-898-5408
Directions
© Trustees of the University of Pennsylvania