Home
Mission
The mission of the Center for Neurodegenerative Disease Research (CNDR) is to promote and conduct multidisciplinary clinical and basic research to increase the understanding of the causes and mechanisms leading to brain dysfunction and degeneration in neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Lewy body dementia (LBD), Frontotemporal degeneration (FTD), Amyotrophic lateral sclerosis (ALS), Primary lateral sclerosis (PLS), Motor neuron disease (MND), and related disorders that occur increasingly with advancing age. Implicit in the mission of the CNDR are two overarching goals: 1.) Find better ways to cure and treat these disorders, 2. Provide training to the next generation of scientists.
“My vision for CNDR is to create a world with effective interventions to prevent and cure aging-related neurodegenerative diseases.” – Eddie Lee, MD, PhD, Director of CNDR
John Q. Trojanowski, MD, PhD | 1946 - 2022
In loving memory of John Q. Trojanowski, MD, PhD
Latest Research
-
Associations Between Occupational Trajectories at Ages 35-55 and Later-Life Cognition in Older Adults in Chile
Friday, July 17, 2026
OBJECTIVES: As global rates of Alzheimer's Disease and Related Dementias (AD/ADRD) increase, understanding the factors that contribute to cognitive aging is crucial. This study examined the association between occupational skill trajectories between ages 35 and 55 and cognitive function among older Chilean adults aged 60 and above. It explored how different patterns of occupational trajectories relate to cognitive performance.
-
Using Multinodal Deep Brain Stimulation for Treatment of Complex Movement Disorders: Initial Case Series
Wednesday, July 15, 2026
CONCLUSION: We present the largest initial case series demonstrating the safety, feasibility, and added efficacy of single system multinodal DBS for treating mixed and complex movement disorders. This approach is safe, provides additional benefit, and warrants further investigation for treating mixed and complex movement disorders.
-
Metabolic syndrome is associated with accelerated brain aging
Tuesday, July 14, 2026
INTRODUCTION: Metabolic syndrome (MetS) is associated with increased dementia risk, but its relationship with brain aging is unclear.