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Center for Neurodegenerative Disease Research

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  • 07/22/17

    This past week, thousands of the world's leading Alzheimer's disease researchers gathered in London to discuss and debate the latest research. Among the questions that captured much attention was what's the right kind of study to discover the best treatments?

  • 07/21/17

    Developing a potent therapy for Alzheimer's disease will be one of the biggest healthcare challenges over the next few decades.

  • 07/01/17

    “Aren't there any sons?”...“Sure aren't. If it’s not daughters, it’s daughters-in-law.” This question and answer exchange is recounted in Making An Exit, Elinor Fuchs’ compelling narrative of her and her mother Lil Kessler’s decade of living with dementia.

  • 06/30/17

    Could new biomarkers predict which Parkinson's disease patients are most likely to suffer early or severe cognitive decline?

  • 05/18/17

    Parkinson's disease affects about half a million people in the United States. New research identifies biomarkers that could predict the cognitive impairment typical of this neurodegenerative disease.

  • 05/01/17

    About a million people in the United States have Parkinson’s disease, a neurological disorder that causes not only physical symptoms, like tremors, muffled speech, and balance problems, but mental symptoms as well.

  • 03/01/17

    Actor David Cassidy, in an emotional appearance on Dr. Phil Wednesday, talked about his memory loss that started in his early 60s. Neurologists at University of Pennsylvania are finding new ways to diagnose and treat the various forms of dementia early.

  • 02/24/17

    The announcement came the day before Thanksgiving, but there was nothing in it to be thankful for: An experimental Alzheimer’s drug many thought would slow the disease’s steady cognitive decline had failed to make a significant difference in a massive trial of people with early signs of the illness.

  • 01/22/17

    You walk into a room and can’t remember what you went there for. You forget someone’s name. You can’t recall the word for something.Is it the normal forgetfulness that goes with aging, or something more serious?

  • 11/29/16

    Researchers at the University of Pennsylvania have developed a new mouse model using tau tangles isolated from the brain's of Alzheimer's patients, giving a more accurate progression of the neurological disease.


Related News Releases

New Alzheimer's Animal Model More Closely Mimics Human Disease

December 4, 2017


Women with Parkinson's Disease Less Likely than Men to Have Caregivers

December 1, 2017


So My Brain Amyloid Level is "Elevated" — What Does That Mean?

October 23, 2017


 Penn Researchers Drill Down into Gene Behind Frontotemporal Lobar Degeneration

October 19, 2017


Mild Cognitive Impairment and Alzheimer's Disease Diagnoses Trigger Lower Self-Ratings of Quality of Life in Older Adults 

August 3, 2017


Newly Discovered Gene Variants Link Innate Immunity and Alzheimer's Disease

July 17, 2017


Higher Resolution View of Yeast Nanomachine Shows How It Breaks Up Protein Tangles One Ratchet at a Time

June 15, 2017


Penn Medicine Researchers Identify New Biomarkers That May Predict Cognitive Impairment in New Parkinson's Disease Patients

May 17, 2017


Link between Common Prostate Cancer Treatment, Dementia Detailed in New Penn Study

March 30, 2017


Deep Brain Stimulation Studies in Alzheimer's Disease Pose Ethical Challenges

January 24, 2017


Orphan Disease Center Announces Program of Excellence for Motor Neuron Disease

January 9, 2017


Evidence of Alzheimer's in Patients with Lewy Body Disease Tracks with Course of Dementia

January 4, 2017


Penn Study Confirms That "Sniff Test" May Be Useful in Diagnosing Early Alzheimer's Disease

December 20, 2016


More Human-like Model of Alzheimer's Better Mirrors Tangles in the Brain

November 15, 2016


Penn Physician Argues for "Meaningful" Update to National Alzheimer's Act

October 19, 2016


Common Prostate Cancer Treatment Tied to Dementia

October 13, 2016


Penn Alzheimer's Disease Center to Receive $8.8 Million in NIH Funding

August 2, 2016


New Penn Neurodegeneration Genomics Center Forms National Hub for Alzheimer's Disease Research

July 18, 2016


Penn Medicine Announces $3 Million Gift to Establish Unique Pulmonary Program for Patients with Amyotrophic Lateral Sclerosis (ALS) and other Neurodegenerative Diseases 

July 12, 2016


Penn Medicine Team and Collaborators Receive NIH Award to Launch Genomics Center on Alzheimer's disease

June 22, 2016


Penn Medicine Scientist Receives $7.5 Million NIH Renewal Grant for Dementia Research

June 20, 2016


Penn MedicineAwarded Fellowship to Train Next Generation of Parkinson's Specialists

April 21, 2016


Penn Study Uncovers Genetic Variation that Predicted Type and Rate of Physical Decline in Patients with Parkinson's Disease

April 14, 2016


Penn Researchers Identify a New Cause of Inherited Neuropathy

March 23, 2016


Antipsychotic Drugs Linked to Increased Mortality Among Parkinson's Disease Patients

March 22, 2016


Penn Medicine Wins NIH Award to Study Progressive Brain Damage from Concussions and More Severe Traumatic Brain Injuries

March 17, 2016


Penn-Engineered Neural Networks Show Hope for Axonal Repair in the Brain, with Minimal Disruption to Brain Tissue

January 19, 2016


Penn's Murray Grossman Receives Special Recognition Award from the Legal Clinic for the Disabled for Dedication to the Disability Community

December 31, 2015


Brain's Hippocampus is Essential Structure for All Aspects of Recognition Memory, Penn Medicine Researchers Find

November 3, 2015


Penn Medicine's John Q. Trojanowski, MD, PhD, Receives Top Honor for Neuropathology Achievement

July 21, 2015


Higher-level Occupations May Increase Survival in Patients with a Common Form of Early-onset Demtia, Finds New Penn Medicine Research

April 22, 2015


Two Penn Medicine Studies Examine Diabetes Severity in Parkinson's and Sex Differences in Parkinson's Caregiving

April 21, 2015


Plasma Ap0A1 Associates with Age at Onset and Motor Severity in Early Parkinson's Disease Patients, Penn Medicine Researchers Find

April 17, 2015


Penn Medicine Researchers Pinpoint Potential New Drug Target for Protection Against Certain Neurodegenerative Diseases

March 20, 2015


Penn Study Uncovers Secrets of a Clump-Dissolving Protein

January 22, 2015


Penn Medicine Biochemist Receives "Bucket Challenge" Funds to Study Biology of Lou Gehrig's Disease

December 17, 2014


Penn Medicine Researchers Receive Funding from CDC to Advance Brain Health

November 13, 2014


Penn Study Finds Dopamine Replacement Therapy Associated with Increase in Impulse Control Disorders Among Early Parkinson's Disease Patients

August 15, 2014


Penn Physiologist Given NIH Javits Neuroscience Investigator Award for Research on Neurodegeneration

August 4, 2014


Penn Medicine Neuropathologist Receives Doris Duke Grant to Study Brain Disorders

August 1, 2014


Penn Researchers Find Naltrexone May Be Effective in Diminishing Impulse Control Disorders in Parkinson's Disease Patients

July 30, 2014


Penn Alzheimer's Researchers to Receive J. Allyn Taylor International Prize in Medicine

July 17, 2014


Penn Medicine Researchers and Collaborators Receive $12.6 Million NIH Grant to Study Genetics of Alzheimer's Disease

July 7, 2014


Penn Study Describes New Models for Testing Parkinson's Disease Immune-based Drugs

June 12, 2014


Quality Control: Penn Study Shows How Misfolded Proteins are Selected for Disposal

May 29, 2014


Can Anti-Depressants Help Prevent Alzheimer's Disease?

May 14, 2014


Role of Calcium in Familial Alzheimer's Disease Clarified in Penn Study, Pointing to New Therapeutic Options

May 13, 2014


Penn Neurologists Report on Promise of Statins, Estrogen and Telemedicine as Potential Targets and Interventions for Parkinson's Disease

April 25, 2014


Penn Medicine Receives $1.45 Million to Speed Research for Rare Neurodegenerative Diseases

April 8, 2014


Penn Medical Ethicist: Policy Changes Urgently Needed as Millions of Americans to Start Receiving Early Label of Alzheimer's Disease

April 7, 2014


Alzheimer's Prevention Trial To Evaluate and Monitor Participants' Reactions to Learning of Higher Disease Risk Status

March 19, 2014


A Common Protein in an Uncommon Role: Unraveling Misfolded Molecules Using "Reprogrammed" Yeast Protein Could Lead to New Brain Disease Therapies

January 16, 2014


Breaking the Brain Clock Predisposes Nerve Cells to Neurodegeneration

November 25, 2013


Penn Medicine Review Finds Statin Use Not Linked to a Decline in Cognitive Function

November 18, 2013


International Group Finds 11 New Alzheimer's Genes to Target for Drug Discovery, Adding New Clues into Complex Disease Puzzle

October 28, 2013


Comprehensive Parkinson's Biomarker Test Has Prognostic and Diagnostic Value, Penn Medicine Team Reports

August 26, 2013


Penn Study Shows Vascular Link in Alzheimer's Disease with Cognition

July 10, 2013


Shape-shifting Disease Proteins May Explain Variable Appearance of Neurodegenerative Diseases, Penn Study Finds

July 3, 2013


Staging System in ALS Shows Potential Tracks of Disease Progression, Penn Study Finds

June 19, 2013