Welcome to the Chemical and Nanoparticle Synthesis Core (CNSC)

The Chemical and Nanoparticle Synthesis Core (CNSC) was established by the Center for Targeted Therapeutics and Translational Nanomedicine (CT3N) to meet the chemical and nanoparticle design and synthesis needs of Penn investigators. The CNSC was formed with support from ITMAT (Clinical and Translational Science Award), the Perelman School of Medicine, the School of Engineering and Applied Science, and the Department of Chemistry (School of Arts and Sciences).

The CNSC supports researchers by providing in-house expertise in medicinal chemistry, metal chelate chemistry, polymer synthesis, and nanoparticle production and surface functionalization. Our chemists provide custom, problem-specific support for researchers in medical, chemical, and materials science fields. Specific services include:

  • Consultation and assistance with the design of chemical/medicinal compounds
  • In-house synthesis of chemical/medicinal compounds
  • Custom nanoparticle design and synthesis
  • Custom nanoparticle surface functionalization (-COOH, -NH2, PEG, -N3, Alkyne, etc.)
  • Polymer and dendrimer Synthesis

In addition to custom services, the CNSC also provides a Catalog of pre-made reactive metal chelates for radiolabeling and other imaging applications, reactive near-infrared imaging agents, hydrophobic and hydrophilic nanoparticles. A list of available products can be found under the ‘Catalog’ pull-down menu on the left.

To schedule an appointment with one of the CNSC chemists to initiate your next CNSC project or to submit a request, please send an email to CNSC@pennmedicine.upenn.edu and we will respond shortly. Please include a brief description of your project, including the chemical structure and amount needed, if known.

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