Perelman School of Medicine at the University of Pennsylvania

Huang Lab


  1. Mishra V, Gundapuneedi T, Guo X, Delgado MR, Huang H, 2015. Towards tract-specific fractional anisotropy (TSFA) at crossing-fiber regions with clinical diffusion MRI. Magnetic Resonance in Medicine 74(6): 1768-1779. [PubMed]
  2. Jeon T, Mishra V, Ouyang M, Chen M, Huang H, 2015. Coherent changes of cortical thickness and corresponding white matter microstructure during brain development accessed by diffusion MRI tractography from parcellated cortex. Frontiers in Neuroanatomy 9:158. [PubMed]
  3. Ouyang A, Jeon T, Sunkin SM, Pletikos M, Sedmak G, Sestan N, Lein ES, Huang H, 2015. Spatial mapping of structural and connectional imaging data for the developing human brain with diffusion tensor imaging. Methods 73: 27-37. [PubMed]
  4. Bauer I, Ouyang A, Mwangi B, Sanches M, Huang H, Soares JC, 2015. Reduced white matter integrity and verbal fluency impairment in adults with bipolar disorder: a diffusion imaging study. Journal of Psychiatric Research 62: 115-122. [PubMed]
  5. Xu F, Liu P, Pascual JM, Xiao G, Huang H, Lu H, 2015. Acute effect of glucose on cerebral blood flow, blood oxygenation, and oxidative metabolism. Human Brain Mapping 36(2): 707-716. [PubMed]
  6. Huang H, Shu N, Mishra V, Jeon T, Chalak L, Zhang Z, Rollins N, Gong G, Cheng H, Peng Y, Dong Q, He Y, 2015. Development of human structural brain networks through infancy and childhood. Cerebral Cortex 25(5): 1389-1404. [PubMed]
  7. Miller J, Ding SL, Sunkin S, Smith K, Ng L, Szafer A, Ebbert A, Riley Z, Aiona K, Arnold J, Bennet C, Bertagnolli D, Brouner K, Butler S, Caldejon S, Carey A, Cuhaciyan C, Dalley R, Dee N, Dolbeare T, Facer B, Feng D, Fliss T, Gee G, Goldy J, Gourley L, Gregor B, Gu G, Howard R, Jochim J, Kuan C, Lau C, Lee C, Lee F, Lemon T, Lesnar P, McMurray B, Mastan N, Mosqueda N, Naluai-Cecchini T, Ngo NK, Nyhus J, Oldre A, Olson E, Parente J, Parker P, Parry S, Player A, Pletikos M, Reding M, Royall J, Roll K, Sandman D, Sarreal M, Shapouri S, Shapovalova N, Shen E, Sjoquist N, Slaughterbeck C, Smith M, Sodt A, Williams D, Zöllei L, Fischl B, Gerstein M, Geschwind D, Glass I, Hawrylycz M, Hevner R,Huang, H, Jones A, Knowles J, Levitt P, Phillips J, Sestan N, Wohnoutka P, Dang C, Bernard A, Hohmann J, Lein E, 2014. Transcriptional landscape of the prenatal human brain. Nature 508: 199-206. Cover Article. [PubMed]
  8. Yu Q, Peng Y, Mishra V, Ouyang A, Li H, Zhang H, Chen M, Liu S, Huang, H, 2014. Microstructure, length, and connection of limbic tracts in normal human brain development. Frontiers in Aging Neuroscience 6: 228. (fngi.2014.00228). [PubMed]
  9. Liu P, Huang, H, Rollins N, Jeon T, Chalak LF, Halovanic C, Lu H, 2014. Quantitative assessment of global cerebral metabolic rate of oxygen (CMRO2) in neonates using MRI. NMR in Biomedicine 27(3): 332-340. [PubMed]
  10. Huang, H, Vasung L, 2014. Gaining insight of fetal brain development with diffusion MRI and histology. International Journal of Developmental Neuroscience 32: 11-22. Cover article.[PubMed]
    Huang, H, et al., International Journal of Developmental Neuroscience 2014 (cover article).
    Huang, H, et al., International Journal of
    Developmental Neuroscience
     2014 (cover article).
  11. Mishra V, Cheng H, Gong G, He Y, Dong Q, Huang, H, 2013. Differences of inter-tract correlations between neonates and children around puberty: A study based on microstructural measurements with DTI. Frontiers in Human Neuroscience 7: 721. [PubMed]
  12. Medin PM, Foster RD, van der kogel AJ, Meyer J, Sayre JW, Huang, H, Oz OK, 2013. Unexpected paralysis in a swine model suggests a tolerance constraint for single-faction irradiation of the spinal nerve. Radiotherapy & Oncology 109: 107-111.
  13. Tseng BY, Gundapuneedi T, Khan MA, Diaz-Arrastia R, Levine BD, Lu H, Huang, H, Zhang R, 2013. White matter integrity in physically fit older adults. Neuroimage 82: 510-516. [PubMed]
  14. Huang, H, Jeon T, Sedmak G, Pletikos M, Vasung L, Xu X, Yarowsky P, Richards L, Kostovic I, Sestan N, Mori S, 2013. Coupling diffusion imaging with histological and gene expression analysis to examine the dynamics of cortical areas across the fetal period of human brain development. Cerebral Cortex 23 (11), 2620-2631. [PubMed]
  15. Jeon T, Mishra V, Uh J, Weiner M, Hatanpaa KJ, White CL, Zhao YD, Lu H, Diaz-Arrastia R, Huang, H, 2012. Regional changes of cortical mean diffusivities with aging and Alzheimer disease after correction of partial volume effects. Neuroimage 62: 1705-1716. [PubMed]
  16. Huang, H, Gundapuneedi T, Rao U, 2012. White matter disruptions in adolescents exposed to childhood maltreatment and vulnerability to psychopathology. Neuropsychopharmacology 37(12), 2693-2701. (Featured with Nature Press Release). [PubMed]
  17. Saxena K, Tamm L, Walley A, Simmons A, Rollins N, Emslie G, Fan X, Huang, H, 2012. A preliminary investigation of corpus callosum and anterior commissure aberrations in aggressive bipolar youth. Journal of Child and Adolescent Psychopharmacology 22(2): 112-119. [PubMed]
  18. Delgado-Ayala M, Smith L, Clegg N, Huang, H, 2012. White matter biomarker of hereditary spastic paraplegia. Annals of Neurology 72: s196-s197.
    Huang, H, et al., 
    Neuropsychopharmacology 2011
    (cover article).
  19. Huang, H, Fan X, Weiner M, Martin-Cook K, Xiao G, Davis J, Devous M, Rosenberg R, 2012. Distinctive disruption patterns of white matter tracts in Alzheimer’s disease with full diffusion tensor characterization. Neurobiology of Aging 33(9): 2029-2045.[PubMed]
  20. Huang, H, Fan X, Williamson DE, Rao U, 2011. White matter changes in healthy adolescents at familial risk for unipolar depression: A diffusion tensor imaging study. Neuropsychopharmacology 36 (3), 684-691. Cover article.[PubMed]
  21. Huang, H, Prince JL, Mishra V, Carass A, Landman B, Park DC, Tamminga C, King R, Miller MI, van Zijl PC, Mori S, 2011. A framework on surface-based connectivity quantification for the human brain. Journal of Neuroscience Methods 197(2), 324-332.[PubMed]
  22. Oishi K, Huang, H, Yoshioka T, Ying S, Zee D, Zilles K, Amunts K, Woods R, Toga AW, Pike GB, Rosa-Neto P, Evans AC, van Zijl PC, Mazziotta JC, Mori S, 2011. Superficially located white matter structures commonly seen in the human and the macaque brain with diffusion tensor imaging. Brain Connectivity 1(1), 37-47. [PubMed]
  23. Aslan S, Huang, H, Uh J, Mishra V, Xiao G, van Osch M, Lu H, 2011. White matter cerebral blood flow is inversely correlated with structural and functional connectivity in the human brain. Neuroimage 56(3), 1145-1153. [PubMed]
  24. Vasung L, Huang, H, Jovanov-Milosevic N, Pletikos M, Mori S, Kostovic I, 2010. Development of axonal pathways in the human fetal fronto-limbic brain: histochemical characterization and diffusion tensor imaging. Journal of Anatomy 217(4), 400-417. [PubMed]
  25. Huang, H, 2010. Structure of the fetal brain: what we are learning from DTI. Neuroscientist 16(6), 634-649. [PubMed]
  26. Huang, H, 2010. Delineating neural structures of developmental brains with diffusion tensor imaging. ScientificWorldJournal 10, 135-144. [PubMed]