F.M. Kirby Center for Molecular Ophthalmology

Kenneth Shindler's Lab

Selected Publications

Shindler KS, Guan Y, Ventura E, Bennett J, Rostami AM: Retinal ganglion cell loss induced by acute optic neuritis in a relapsing model of multiple sclerosis. Multiple Sclerosis 12: 526-532, 2006.


Shindler KS, Ventura E, Rex, TS, Elliott P, Rostami A: SIRT1 activation confers neuroprotection in experimental optic neuritis. Invest. Ophthalmol. Vis. Sci. 48(8): 3602-3609, August  2007.


Shindler KS, Kenyon LC, Dutt M, Hingley ST, Das Sarma J: Experimental optic neuritis induced by a demyelinating strain of mouse hepatitis virus. J. Virol. 82(17): 8882-8886, Sept 2008.


Shindler KS, Ventura E, Dutt M, Rostami AM: Inflammatory demyelination induces axonal injury and retinal ganglion cell apoptosis in experimental optic neuritis. Exp. Eye Res. 87(3): 208-213, Sept 2008.


Das Sarma J, Kenyon LC, Hingley ST, Shindler KS: Mechanisms of primary axonal damage in a viral model of multiple sclerosis  J. Neurosci. 29(33): 10272-10280, Aug 2009.


Dutt M, Tabuena P, Ventura E, Rostami AM, Shindler KS: Timing of corticosteroid therapy is critical to prevent retinal ganglion cell loss in experimental optic neuritis. Invest. Ophthalmol. Vis. Sci. 51(3): 1439-1445, Mar 2010.


Shindler KS, Ventura E, Dutt M, Elliott P, Fitzgerald DC, Rostami A: Oral resveratrol reduces neuronal damage in a model of multiple sclerosis. J. of Neuro-Ophthalmol. 2010, In press.

University of Pennsylvania | Perelman School of Medicine