Selected Publications and Abstracts
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Peer-Reviewed Journal Articles
Selection of Published Research
1. Glauser, G., Piazza, M., Berger, I., Osiemo, B., McClintock, SD., Winter, E., Chen, HI., Ali, ZS., Malhotra, NR. The Risk Assessment and Prediction Tool (RAPT) for Discharge Planning in a Posterior Lumbar Fusion Population. Neurosurgery. 2020 Feb 1;86(2):E140-E146. doi: 10.1093/neuros/nyz419. PMID: 31599332
Conclusion: Preoperative RAPT score is a highly predictive tool in lumbar fusion patients for discharge disposition.
Pubmed link: https://www.ncbi.nlm.nih.gov/pubmed/31599332
2. Glauser, G., Caplan, IF., Winter, E., Goodrich, S., McClintock, SD., Atluri, P., Malhotra, NR. Evaluation of the LACE+ Index for Short-Term Cardiac Surgery Outcomes: A Coarsened Exact Match Study. Ann Thorac Surg. 2020 Jul;110(1):173-182. doi: 10.1016/j.athoracsur.2019.09.062. Epub 2019 Nov 9. PMID: 31715156
Conclusion: The LACE+ index may be suitable as a prediction model for important patient outcomes in a cardiac surgery population.
Pubmed link: https://www.ncbi.nlm.nih.gov/pubmed/31715156
3. Glauser, G., Sharma, N., Kritikos, ME., Malhotra, NR., Choudhri, O. Cervical, Intradural Extramedullary Solitary Fibrous Tumor of the Spinal Cord: A Case Report and Review of the Literature. Asian J Neurosurg. 2020 Feb 25;15(1):204-209. doi: 10.4103/ajns.AJNS_213_19. eCollection Jan-Mar 2020. PMID: 32181204
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32181204
4. Glauser, G., Goodrich, S., McClintock, SD., Szeto, WY., Atluri, P., Acker, MA., Malhotra, NR. Association of Overlapping Cardiac Surgery with Short-Term Patient Outcomes. The Journal of Thoracic and Cardiovascular Surgery. 2020 Jan 9;S0022-5223(20)30028-3. doi: 10.1016/j.jtcvs.2019.11.136. Online ahead of print. PMID: 32014329
Conclusion: Nonconcurrent, overlapping surgery is not associated with an increase in adverse outcomes in a large, matched cardiac surgery population.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32014329
5. Glauser, G., Osiemo, B., Goodrich, S., McClintock, SD., Weber, KL., Levin, LS., Malhotra, NR. Assessment of Short-Term Patient Outcomes Following Overlapping Orthopedic Surgery at a Large Academic Medical Center. J Bone Joint Surg Am. 2020 Apr 15;102(8):654-663. doi: 10.2106/JBJS.19.00554. PMID: 32058352
Conclusion: Nonconcurrent overlapping surgery was not associated with adverse outcomes in a large, matched orthopaedic surgery population across 1 academic health system.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32058352
6. Glauser, G., Winter, E., Caplan, IF., Haldar, D., Goodrich, S., McClintock, SD., Guzzo, TJ., Malhotra, NR. The LACE+ Index as a Predictor of 90-Day Urologic Surgery Outcomes. World Journal of Urology. 2020 Jan 17. doi: 10.1007/s00345-019-03064-3. Online ahead of print. PMID: 31953579
Conclusion: These results suggest that LACE + may be a suitable prediction model for important patient outcomes after urologic surgery.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/31953579
7. Glauser, G., Goodrich, S., McClintock, SD., Dimentberg, R., Guzzo, TJ., Malhotra, NR. Evaluation of Overlapping Urologic Surgery on Short-Term Patient Outcomes at a Large Academic Medical Center. Urology. 2020 Apr;138:30-36. doi: 10.1016/j.urology.2019.12.031. Epub 2020 Jan 21. PMID: 31978529
Conclusion: Nonconcurrent overlapping surgery is not associated with adverse outcomes in a large, matched urologic surgery population across 1 academic health system.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/31978529
8. Glauser, G., Winter, E., Caplan, IF., Goodrich, S., McClintock, SD., Srinivas, SK., Malhotra, NR. Predictive Index for 90 Day Postoperative Outcomes Following Gynecologic Surgery. Am J Manag Care. 2020 Jul;26(7):303-309. doi: 10.37765/ajmc.2020.43760. PMID: 32672915
Conclusion: The results of this study suggest that the LACE+ index is suitable as a prediction model for important patient outcomes in a gynecologic surgery population.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32672915
9. Glauser, G., Winter, E., Caplan, IF., Goodrich, S., McClintock, SD., Srinivas, SK., Malhotra, NR. Composite Score for Outcome Prediction at 30 Days in Gynecologic Surgery Patients. J Healthc Qual. 2020 Mar 4. doi: 10.1097/JHQ.0000000000000254. Online ahead of print. PMID: 32134807
Conclusion: The data presented here suggest that LACE+ index is a viable metric for patient outcome prediction following gynecologic surgery.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32134807
10. Glauser, G., Dimentberg, R., Shultz, K., McClintock, SD., Malhotra, NR. Survival Disparity Based on Household Income in 1,970 Patients Following Brain Tumor Surgery. World Neurosurgery. 2020 Jul 11;S1878-8750(20)31527-8. doi: 10.1016/j.wneu.2020.07.016. Online ahead of print. PMID: 32663636
Conclusion: Patients matched on a multitude of characteristics, of lesser household income, had higher long-term mortality after brain tumor resection.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32663636
11. Glauser, G., Wathen, C., Miranda, SP., Blue, R., Dimentberg, R., Welch, WC., Lee, JYK., Malhotra, NR. Implementation and Workflow of a Telehealth Clinic in Neurosurgery During the COVID-19 Pandemic. World Neurosurgery. 2020 Jul;139:373-375. doi: 10.1016/j.wneu.2020.05.098. Epub 2020 May 16. PMID: 32426067
Conclusion: Telehealth presents a viable option to continue treating patients during the pandemic and offers numerous benefits for both patients and providers, which may be carried over into the post-COVID period.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32426067
12. Caplan, IF., Glauser, G., Goodrich, S., Chen, HI., Lucas, TH., Lee, JYK., McClintock, SD., Malhotra, NR. Undiagnosed obstructive sleep apnea as a predictor of 90-day readmission for brain tumor patients. World Neurosurgery. 2020 Feb;134:e979-e984. doi: 10.1016/j.wneu.2019.11.050. Epub 2019 Nov 14. PMID: 31734423
Conclusion: The results of this study suggest that undiagnosed OSA, as evaluated by the STOP-Bang questionnaire, is an effective predictor of readmission risk and health system utilization in a brain tumor craniotomy population with previously undiagnosed OSA.
Pubmed link: https://www.ncbi.nlm.nih.gov/pubmed/31734423
13. Winter, E., Glauser, G., Caplan, IF., Goodrich, S., McClintock, SD., Kovach, SJ., Fosnot, J., Serletti, JM., Malhotra, NR. The LACE+ Index as a Predictor of 30-Day Patient Outcomes in a Plastic Surgery Population: A Coarsened Exact Match Study. Plast Reconstr Surg. 2020 Sep;146(3):296e-305e. doi: 10.1097/PRS.0000000000007064. PMID: 32453271
Conclusion: The results of this study demonstrate that the LACE+ index may be suitable as a prediction model for patient outcomes in a plastic surgery population.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32453271
14. Winter, E., Glauser, G., Caplan, IF., Goodrich, S., McClintock, SD., Kovach, SJ., Fosnot, J., Serletti, JM., Malhotra, NR. LACE+ Index as a Predictor of 90-Day Plastic Surgery Outcomes. Am J Manag Care. 2020 Apr 1;26(4):e113-e120. doi: 10.37765/ajmc.2020.42838. PMID: 32270988
Conclusion: The results of this study demonstrate that the LACE+ index may be suitable as a prediction model for patient outcomes in a plastic surgery population.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32270988
15. Agarwal, P., Glauser, G., Malhotra, NR. In Reply: Association of Overlapping Neurosurgery With Patient Outcomes at a Large Academic Medical Center. 2020 Jun 1;86(6):E586. doi: 10.1093/neuros/nyaa048. PMID: 32133528
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32133528
16. Caplan, IF., Sinha, S., Osiemo, B., McClintock, SD., Schuster, JM., Smith, H., Glauser, G., Sharma, N., Ozturk, AK., Ali, ZS., Malhotra, NR. The utility of cervical spine bracing as a postoperative adjunct to multilevel anterior cervical spine surgery. Int J Spine Surg. 2020 Apr 30;14(2):151-157. doi: 10.14444/7022. eCollection 2020 Apr. PMID: 32355619
Conclusion: Bracing following multilevel cervical fixation does not alter short-term postoperative course or reduce the risk for early adverse outcomes in a significant manner.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32355619
17. Kvint, S., Malhotra, NR., Cox, M., Mondschein, JI., Pukenas, BA, Bagley, LJ. Giant Iliac Artery Pseudoaneurysm Mimicking Postoperative Fluid Collection and Diskitis. World Neurosurgery. 2020 Apr;136:253-257. doi: 10.1016/j.wneu.2019.11.176. Epub 2019 Dec 6. PMID: 31816453
Conclusion: Complex paraspinal fluid collections causing osseous erosions should raise the possibility of an aneurysm/pseudoaneurysm.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/31816453
18. Haldar, D., Glauser, G., Winter, E., Dimentberg, R., Goodrich, S., Shultz, K., Grady, MS., McClintock, SD., Malhotra, NR. The Effect of Race on Short-Term Pituitary Tumor Outcomes. World Neurosurgery. 2020 May;137:e447-e453. doi: 10.1016/j.wneu.2020.01.241. Epub 2020 Feb 10. PMID: 32058115
Conclusion: This study suggests that the effect of race on outcomes is partly mitigated for individuals who can attain access, and when socioeconomic factors and comorbidities are controlled for.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32058115
19. Haldar, D., Glauser, G., Schuster, JM., Winter, E., Goodrich, S., Shultz, K., McClintock, SD., Malhotra, NR. The Role of Race in Short Term Outcomes for 1700 Consecutive Patients Undergoing Brain Tumor Resection. J Healthc Qual. 2020 Jun 9. doi: 10.1097/JHQ.0000000000000267. Online ahead of print. PMID: 32544138
Conclusion: This study suggests that race does not independently influence postsurgical outcomes but may instead serve as a proxy for other closely related demographics.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32544138
20. Haldar, D., Glauser, G., Winter, E., Goodrich, S., Shultz, K., McClintock, SD., Malhotra, NR. Assessing the Role of Patient Race in Disparity of 90-Day Brain Tumor Resection Outcomes. World Neurosurgery. 2020 Jul;139:e663-e671. doi: 10.1016/j.wneu.2020.04.098. Epub 2020 Apr 29. PMID: 32360924
Conclusion: This study suggests that race alone does not result in disparate outcomes; however, there was an associated difference in 90-day postsurgical readmissions. Despite coarsened exact matching, persistent differences in median household income may play a role in the disparate outcome noted.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32360924
21. Caplan, IF., Winter, E., Glauser, G., Goodrich, S., McClintock, SD., Milby, AH., Hume, EL., Malhotra, NR. Composite Score for Prediction of 30-Day Orthopaedic Surgery Outcomes. J Orthop Res. 2020 Oct;38(10):2189-2196. doi: 10.1002/jor.24673. Epub 2020 Apr 4. PMID: 32221994
Conclusion: Higher LACE+ scores predicted increased risk of readmission, ED visits, and reoperation within 30-days in a heterogeneous, orthopaedic surgery population.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32221994
22. Winter, E., Haldar, D., Glauser, G., Caplan, IF., Shultz, K., McClintock, SD., Chen, HI., Yoon, J., Malhotra, NR. The LACE+ Index as a Predictor of 90-Day Supratentorial Tumor Surgery Outcomes. Neurosurgery. 2020 Jun 15;nyaa225. doi: 10.1093/neuros/nyaa225. Online ahead of print. PMID: 32542339
Conclusion: LACE+ may be suitable for characterizing risk of certain perioperative events in a patient population undergoing supratentorial brain tumor resection.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32542339
23. Sinha, S., Caplan, IF., Schuster, JM., Piazza, M., Glauser, G., Sharma, N., Welch, WC., Osiemo, B., McClintock, SD., Ozturk, AK., Malhotra, NR. Evaluation of lumbar spine bracing as a postoperative adjunct to single-level posterior lumbar spine surgery. Asian J Neurosurg. 2020 May 29;15(2):333-337. doi: 10.4103/ajns.AJNS_35_20. eCollection Apr-Jun 2020. PMID: 32656128
Conclusion: Short-term data suggest that removal of bracing from the postoperative regimen for PLF will not result in increased adverse outcomes but will reduce cost.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32656128
24. Miranda, SP., Glauser, G., Wathen, C., Blue, R., Dimentberg, R., Welch, WC., Grady, MS., Schuster, JM., Malhotra, NR. Incorporating Telehealth to Improve Neurosurgical Training During the COVID-19 Pandemic. World Neurosurgery. 2020 Jul;139:728-731. doi: 10.1016/j.wneu.2020.05.116. Epub 2020 May 17. PMID: 32426069
Conclusion: At our institution, efficient adoption of telehealth clinic and virtual technology has presented a unique opportunity to enhance resident training despite these constraints, by leveraging traditional educational theories.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32426069
25. Winter, E., Dimentberg, R., Haldar, D., Glauser, G., Caplan, IF., Shultz, K., McClintock, SD., Chen, HI., Yoon, JW., Malhotra, NR. Predicting Short Term Outcomes Following Supratentorial Tumor Surgery. Clinical Neurology and Neurosurgery. 2020 Sep;196:106016. doi: 10.1016/j.clineuro.2020.106016. Epub 2020 Jun 20. PMID: 32619899
Conclusion: LACE + may not be suitable for characterizing short-term risk of certain perioperative events in a patient population undergoing supratentorial brain tumor surgery.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32619899
26. Dimentberg, R., Caplan, IF., Winter, E., Glauser, G., Goodrich, S., McClintock, SD., Hume, EL., Malhotra, NR. Prediction of Adverse Outcomes Within 90 Days of Surgery in a Heterogeneous Orthopaedic Surgery Population. Journal Healthc Qual. 2020 Aug 7. doi: 10.1097/JHQ.0000000000000280. Online ahead of print. PMID: 32773485
Conclusion: The results suggest that the LACE+ risk-prediction tool may accurately predict patients with a high likelihood of adverse outcomes after a broad array of orthopedic procedures.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32773485
27. Blue, R., Dimentberg, R., Detchou, DK., Glauser, G., Shultz, K., McClintock, SD., Malhotra, NR. The Impact of Household Economics on Short-Term Outcomes in a Posterior Fossa Tumor Population. Cureus. 2020 Jul 2;12(7):e8968. doi: 10.7759/cureus.8968. PMID: 32766010
Conclusion: This study suggests that low SES, when defined by household income, correlates with increased mortality within 30 days and an increased need for return to surgery within 30 days.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32766010
28. Spadola, M., Farooqi, A., Dimentberg R., Blue, R., Shultz, K., McClintock, SD., Malhotra, NR. The Effect of Household Income on Outcomes Following Supratentorial Meningioma Resection. Clin Neurol Neurosurg. 2020 Jun 17;195:106031. doi: 10.1016/j.clineuro.2020.106031. Online ahead of print. PMID: 32652393
Conclusion: Following supratentorial meningioma resection, a lower median household income was significantly associated with increased emergency department visits within 90 post-operative days.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32652393
29. Blue, R., Detchou, DK., Dimentberg, R., Shultz, K., Spadola, M., McClintock, SD., Malhotra, NR. The Influence of Household Income on Survival Following Posterior Fossa Tumor Resection at a Large Academic Medical Center. J Neurol Surg B Skull Base. (Accepted) PMID:
Conclusion: This study suggests that lower household income is associated with increased mortality in both the 90-day window and total follow-up period.
30. Glauser, G., Ali, ZS., Gardiner, D., Ramayya, AG., Pessoa, R., Grady, MS., Welch, WC., Zager, EL., Sim, E., Haughey, V., Wells, B., Restuccia, M., Tait, G., Fala, G., Malhotra, NR. Assessing the Utility of an IoS Application in the Perioperative Care of Spine Surgery Patients: The NeuroPath Pilot Study. mHealth. 2019 Sep 24;5:40. doi: 10.21037/mhealth.2019.09.01. eCollection 2019. PMID: 31620467
Conclusion: This pilot study of the NeuroPath app demonstrates its potential utility for improving quality of patient care without increased costs.
Pubmed link: https://www.ncbi.nlm.nih.gov/pubmed/31620467
31. Sullivan, PZ., Albayar A., Ramayya, AG., McShane, B., Marcotte, P., Malhotra, NR., Ali, ZS., Chen, HI., Janjua, MB., Saifi, C., Schuster, J., Grady, MS., Jones, J., Ozturk, AK. Association of spinal instability due to metastatic disease with increased mortality and a proposed clinical pathway for treatment. J Neurosurg Spine. 2020 Feb 14;1-8. doi: 10.3171/2019.11.SPINE19775. Online ahead of print. PMID: 32059185
Conclusion: At the authors' institution, patients with gross mechanical instability per the SINS system had an increased rate of 30-day postoperative mortality, which remained significant when controlling for other factors.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32059185
32. Zhang, C., Gullbrand, SE., Schaer, TP., Lau, YK., Zhirui, J., Dodge, GR., Elliott, DM., Mauck, RL., Malhotra, NR., Smith, LJ. Inflammatory cytokine and catabolic enzyme expression in a goat model of intervertebral disc degeneration. J Orthop Res. 2020 Feb 24;10.1002/jor.24639. doi: 10.1002/jor.24639. Online ahead of print. PMID: 32091156
Conclusion: These results demonstrate that degenerate goat discs exhibit elevated expression of clinically relevant inflammatory mediators, and further validate this animal model as a platform for evaluating new therapeutic approaches for disc degeneration.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32091156
33. Gutierrez, A., Su, YS., Vaughan, KA., Miranda, S., Chen, HI., Petrov, D., Malhotra, NR., Schuster, JM. Penetrating Spinal Column Injuries (pSI): An Institutional Experience with 100 Consecutive Cases in an Urban Trauma Center. World Neurosurgery. 2020 Jun;138:e551-e556. doi: 10.1016/j.wneu.2020.02.173. Epub 2020 Mar 7. PMID: 32156595
Conclusion: Management of pSI in urban trauma centers is complex, as these victims routinely have polytrauma that takes precedence. Indications for surgical intervention are narrow and secondary to surgery for polytrauma.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32156595
34. Blue, R., Yang, AI., Zhou, C., De Ravin, E., Teng, CW., Arguelles, GR., Huang, V., Wathen, C., Miranda, SP., Marcotte, P., Malhotra, NR., Welch, WC., Lee, JYK. Telemedicine in the Era of Coronavirus Disease 2019 (COVID-19): A Neurosurgical Perspective. 2020 Jul;139:549-557. doi: 10.1016/j.wneu.2020.05.066. Epub 2020 May 16. PMID: 32426065
Conclusion: In the era of COVID-19 and beyond, telemedicine remains a promising and effective approach to continue neurologic patient care.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32426065
35. Zhang, C., Gullbrand, S., Schaer, TP., Boorman, S., Elliott, DM., Chen, W., Dodge, GR., Mauck, RL., Malhotra, NR., Smith, LJ. Combined Hydrogel and Mesenchymal Stem Cell Therapy for Moderate Severity Disc Degeneration in Goats. Tissue Eng Part A. 2020 Aug 7. doi: 10.1089/ten.TEA.2020.0103. Online ahead of print. PMID: 32546053
Conclusion: In this study, using a clinically relevant goat model of moderate-severity disc degeneration, we demonstrate that a combined interpenetrating network hydrogel and mesenchymal stem cell therapy provides acute improvements in disc height, histological condition, and local inflammation.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32546053
36. Detchou, DK., Dimentberg, R., Vaughan, KA., Kolster, R., Braslow, BM., Malhotra, NR. Navigated Ultrasonic Osteotomy to Aid in En Bloc Chordoma Resection via Spondylectomy. 2020 Aug 10;143:319-324. doi: 10.1016/j.wneu.2020.08.021. Online ahead of print. PMID: 32791231
Conclusion: This approach offers a promising technological adjunct for the treatment of complex spine tumors requiring precise resection and reconstruction.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32791231
37. Farooqi, A., Dimentberg, R., Shultz, K., McClintock, SD., Malhotra, NR. Absence of Gender Disparity in 30-Day Morbidity and Mortality After Supratentorial Brain Tumor Resection. World Neurosurgery. 2020 Aug 27;S1878-8750(20)31915-X. doi: 10.1016/j.wneu.2020.08.146. Online ahead of print. PMID: 32861902
Conclusion: When gender is isolated from race, household economics, and other key factors, it does not seem to independently predict morbidity or mortality in the short-term postoperative window after supratentorial brain tumor resection.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32861902
38. Glauser, G., Sharma, N., Beatson, N., Dimentberg, R., Savarese, F., Gagliardi, M., Grady, MS., Malhotra, NR. Surgical CPT Coding Discrepancies: Analysis of Surgeons and Employed Coders. Am J Med Qual. 2020 Sep 22;1062860620959440. doi: 10.1177/1062860620959440. Online ahead of print. PMID: 32959674
Conclusion: These results demonstrate the existence of coding discrepancies. Future investigation will evaluate the communication between surgeons and billing professionals.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/32959674
39. Detchou, DK., Glauser, G., Dimentberg, R., Maloney, E., Yoshor, D., Malhotra, NR. Letter to the Editor: The Frazier Scholar Program at Penn Neurosurgery: An Adaptable Model for Nurturing Early Interest in Neurosurgery for Current and Aspiring Medical Students. J Neurosurg (Accepted)
Conclusion: In only a short time, the Frazier Scholar Program has increased opportunities for meaningful research exposure in neurosurgery for medical and pre-medical students, while promoting close mentorship with residents and attendings.
40. Dimentberg, R., Sinha, S., Glauser, G., Caplan, IF., Schuster, JM., McClintock, SD., Yoon, J., Marcotte, PJ., Ali, Z., Malhotra, NR. Short-Term Impact of Bracing in Multi-Level Posterior Lumbar Spinal Fusion. Journal of Spine Surgery. (Accepted)
Conclusion: Bracing following multi-level posterior lumbar fixation does not alter short-term post-operative course or reduce the risk for early adverse events.
41. Caplan, IF., Sullivan, PZ., Glauser, G., Choudhri, O., Kung, D., O’Rourke, DM., Osiemo, B., Goodrich, S., McClintock, SD., Malhotra, NR. The LACE+ index fails to predict 30-90 day readmission for supratentorial craniotomy patients: A retrospective series of 238 surgical procedures. Clinical Neurology and Neurosurgery. 2019 Jul;182:79-83. doi: 10.1016/j.clineuro.2019.04.026. Epub 2019 May 1. PMID: 31102908
Conclusion: The results of this study show that the LACE + index is ill-equipped to predict 30-90 day readmissions in the brain tumor population and further analysis of significant covariates or other prediction tools should be undertaken.
Pubmed link: https://www.ncbi.nlm.nih.gov/pubmed/31102908
42. Caplan, IF., Glauser, G., Goodrich, S., Chen, HI., Lucas, TH., Lee, JYK., McClintock, SD., Malhotra, NR. Undiagnosed obstructive sleep apnea as a predictor of 30-day readmission for brain tumor patients. Journal of Neurosurgery. 2019 Jul 19;1-6. doi: 10.3171/2019.4.JNS1968. Online ahead of print. PMID: 31323636
Conclusion: The results of this study suggest that undiagnosed OSA, as assessed via the STOP-Bang questionnaire, is a significant predictor of patient health status and readmission risk in the brain tumor craniotomy population.
Pubmed link: https://www.ncbi.nlm.nih.gov/pubmed/31323636
43. Glauser, G., Agarwal, P., Ramayya, AG., Chen, HI., Lee, JYK., Schuster, JM., Osiemo, B., Goodrich, S., Smith, LJ., McClintock, SD., Malhotra, NR. Association of Surgical Overlap During Wound Closure with Patient Outcomes Amongst Neurological Surgery Patients at a Large Academic Medical Center. Neurosurgery. 2019 Nov 1;85(5):E882-E888. doi: 10.1093/neuros/nyz142. PMID: 31058970
Conclusion: Surgical overlap during wound closure (STO) is associated with improved or at least noninferior patient outcomes, as it pertains to readmissions and wound revisions.
Pubmed link: https://www.ncbi.nlm.nih.gov/pubmed/31058970
44. Ramayya, AG., Glauser, G., Mcshane, B., Branche, M., Sinha, S., Kvint, S., Buch, V., Abdullah, KG., Kung, DK., Chen, HI., Malhotra, NR., Ozturk, AK. Factors Predicting Ventriculostomy Revision at a Large Academic Medical Center. World Neurosurgery. 2019 Mar;123:e509-e514. doi: 10.1016/j.wneu.2018.11.196. Epub 2018 Nov 29. PMID: 30503293
Conclusion: Bedside external ventricular drain placement is associated with a 15% rate of revision, that typically occurred after drain blockage and postprocedure hemorrhage.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/30503293
45. Petrov, D., Spadola, M., Berger, C., Glauser, G., Mahmoud, A., O’Malley, B., Malhotra, NR. Novel Approach using Ultrasonic Bone Curettage and TransOral Robotic Surgery for En Bloc Resection of Cervical Spine Chordoma. Journal of Neurosurgery: Spine. 2019 Mar 1;1-6. doi: 10.3171/2018.11.SPINE181162. Online ahead of print. PMID: 30835711
Conclusion: In this case report, authors describe the first-documented transoral approach using both transoral robotic surgery (TORS) for exposure and the Sonopet bone scalpel under navigational guidance to achieve en bloc resection of a cervical chordoma.
Pubmed link: https://www.ncbi.nlm.nih.gov/pubmed/30835711
46. Berger, I., Piazza, M., Sharma, N., Glauser, G., Osiemo, B., McClintock, SD., Lee, JYK., Schuster, JM., Ali, ZS., Malhotra, NR. Evaluation of the Risk Assessment and Prediction Tool for Post-Operative Disposition Needs After Cervical Spine Surgery. Neurosurgery. 2019 Nov 1;85(5):E902-E909. doi: 10.1093/neuros/nyz161. PMID: 31134280
Conclusion: RAPT score combined with age is a useful tool in the cervical spine surgery population to predict postdischarge needs.
Pubmed link: https://www.ncbi.nlm.nih.gov/pubmed/31134280
47. Jivraj, I., Liu, GT., Sharma, N., Glauser, G., Grady, MS., Malhotra, NR. Resolution of Papilledema Associated with Chiari I Malformation with Ventriculoperitoneal Shunting. Asian J Neurosurg Apr-Jun 2019;14(2):598-601. doi: 10.4103/ajns.AJNS_33_19. PMID: 31143293
Conclusion: We present a case of a patient with bilateral papilledema and CMI but with no long-standing CMI symptoms.
Pubmed link: https://www.ncbi.nlm.nih.gov/pubmed/31143293
48. Agarwal, P., Ramayya, AG., Osiemo, B., Goodrich, S., Glauser, G., McClintock, SD., Chen, HI., Schuster, JM., Grady, MS., Malhotra, NR. Association of Overlapping Neurosurgery with Patient Outcomes at a Large Academic Medical Center. Neurosurgery. 2019 Dec 1;85(6):E1050-E1058. doi: 10.1093/neuros/nyz243. PMID: 31432069
Conclusion: Overlapping neurosurgery is associated with noninferior patient outcomes that may be driven by surgeon selection of healthier patients, regardless of specific overlap timing.
Pubmed link: https://www.ncbi.nlm.nih.gov/pubmed/31432069
49. Caplan, IF., Sinha, S., Schuster, JM., Piazza, M., Glauser, G., Osiemo, B., McClintock, SD., Welch, WC., Sharma, N., Ozturk, AK., Malhotra, NR. The Utility of Cervical Spine Bracing as a Postoperative Adjunct to Single-Level Anterior Cervical Spine Surgery. Asian J Neurosurg. Apr-Jun 2019;14(2):461-466. doi: 10.4103/ajns.AJNS_236_18. PMID: 31143262
Conclusion: Bracing following single-level cervical fixation does not alter short-term postoperative course or reduce the risk for early adverse outcomes in a significant manner.
Pubmed link: https://www.ncbi.nlm.nih.gov/pubmed/31143262
50. Ramayya, AG., Chen, HI., Marcotte, PJ., Brem, S., Zager, EL., Osiemo, B., Piazza, M., Sharma, N., McClintock, SD., Schuster, JM., Ali, ZS., Connolly, P., Heuer, GG., Grady, MS., Kung, DK., Ozturk, AK., O’Rourke, DM., Malhotra, NR. Assessing variability in surgical decision making among attending neurosurgeons at an academic center. J Neurosurg. 2019 May 31;1-7. doi: 10.3171/2019.2.JNS182658. Online ahead of print. PMID: 31151100
Conclusion: There was general agreement among neurosurgeons in terms of indication for surgery; however, revision surgery of all types and spine surgery with fusion procedures had the lowest amount of decision consensus.
Pubmed link: https://www.ncbi.nlm.nih.gov/pubmed/31151100
51. Caplan, IF., Sullivan, PZ., Kung, D., O’Rourke, DM., Choudhri, O., Glauser, G., Osiemo, B., Goodrich, S., McClintock, SD., Malhotra, NR. The LACE+ index as a predictor of 30-day readmission in a brain tumor population. World Neurosurgery. 2019 Jul;127:e443-e448. doi: 10.1016/j.wneu.2019.03.169. Epub 2019 Mar 27. PMID: 30926557
Conclusion: The results of this study demonstrate that the LACE+ index is not yet suitable as a prediction model for 30-day readmission in a brain tumor population.
Pubmed link: https://www.ncbi.nlm.nih.gov/pubmed/30926557
52. Glauser, G., Osiemo, B., Goodrich, S., McClintock, SD., Vollmer, C., DeMatteo, R., Malhotra, NR. Association of Overlapping, Nonconcurrent, Surgery with Patient Outcomes at a Large Academic Medical Center: A Coarsened Exact Matching Study. Ann Surg. 2019 Oct;270(4):620-629. doi: 10.1097/SLA.0000000000003494. PMID: 31348043
Conclusion: Overlapping, nonconcurrent surgery is not associated with an increase in reoperation, readmission, ER visits, or unanticipated return to surgery.
Pubmed link: https://www.ncbi.nlm.nih.gov/pubmed/31348043
53. Peck, SH., Bendigo, JR., Tobias, JW., Dodge, GR., Malhotra, NR., Mauck, RL., Smith, LJ. Hypoxic Preconditioning Enhances Bone Marrow-Derived Mesenchymal Stem Cell Survival in a Low Oxygen and Nutrient-Limited 3D Microenvironment. Cartilage. 2019 Apr 11;1947603519841675. doi: 10.1177/1947603519841675. Online ahead of print. PMID: 30971109
Conclusion: These results strongly support the use of hypoxic preconditioning to improve postimplantation MSC survival in avascular tissues such as disc and cartilage.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/30971109
54. Smith, LJ., Silverman, L., Sakai, D., Le Maitre, CL., Mauck, RL., Malhotra, NR., Lotz, JC., Buckley, CT. Advancing cell therapies for intervertebral disc regeneration from the lab to the clinic: Recommendations of the ORS spine section. JOR Spine. 2018 Dec;1(4):e1036. doi: 10.1002/jsp2.1036. Epub 2018 Oct 8. PMID: 30895277
Conclusion: In this perspective we highlight primary obstacles and provide recommendations to help accelerate successful clinical translation of cell-based disc regeneration therapies.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/30895277
55. Nayak, NR., Stephen, JH., Piazza, MA., Obayemi, AA., Stein, SC., Malhotra, NR. Quality of Life in Patients Undergoing Spine Surgery: Systematic Review and Meta-Analysis. Global Spine J. 2019 Feb;9(1):67-76. doi: 10.1177/2192568217701104. Epub 2018 Jul 29. PMID: 30775211
Conclusion: The pooled HRQoL values presented in this study may be used by practitioners who would otherwise be precluded from quantifying their surgical outcomes due to a lack of baseline data.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/30775211
56. Ali, ZS., Flanders, TM., Ozturk, AK., Malhotra, NR., Leszinsky, L., McShane, BJ., Gardiner, D., Rupich, K., Chen, HI., Schuster, J., Marcotte, PJ., Kallan, MJ., Grady, MS., Fleisher, LA., Welch, WC. Enhanced recovery after elective spinal and peripheral nerve surgery: pilot study from a single institution. J Neurosurg Spine. 2019 Jan 25;1-9. doi: 10.3171/2018.9.SPINE18681. Online ahead of print. PMID: 30684933
Conclusion: Implementation of this novel ERAS pathway safely reduces patients' postoperative opioid requirements during hospitalization and 1 month postoperatively. ERAS results in improved postoperative mobilization and ambulation.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/30684933
57. Sharma, N., Piazza, M., Marcotte, PJ., Welch, W., Ozturk, AK., Chen, HI., Ali, ZS., Schuster, J., Malhotra, NR. Implications of anesthetic approach, spinal versus general, for the treatment of spinal disc herniation. J Neurosurg Spine. 2018 Nov 2;30(1):78-82. doi: 10.3171/2018.7.SPINE18460. PMID: 30497221
Conclusion: Both SA and GA exhibit the qualities of a good anesthetic, and the utilization of these modalities for lumbar spine surgery is safe and effective.
Pubmed link: https://www.ncbi.nlm.nih.gov/pubmed/30497221
58. McCann, AC., Berger, C., Mahmoud, AF., Kuan, EC., Malhotra, NR., O’Malley, BW Jr. Novel approach using transoral robotic surgery for resection of cervical spine chordoma. Laryngoscope. 2019 Jun;129(6):1395-1399. doi: 10.1002/lary.27489. Epub 2018 Nov 19. PMID: 30456816
Conclusion: To obtain en bloc resection of the lesion while both overcoming limitations due to access and without introducing morbidity from traditional anterior approaches, we elected using transoral robotic surgery for resection.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/30456816
59. Hitti, FL., McShane, BJ., Yang, AI., Rinehart, C., Albayar, A., Branche, M., Malhotra, NR., Janjua, MB., Ali, ZS., Schuster, JM., Ozturk, AK. Predictors of Failure of Nonoperative Management Following Subaxial Spine Trauma and Creation of Modified Subaxial Injury Classification System. World Neurosurg. 2019 Feb;122:e1359-e1364. doi: 10.1016/j.wneu.2018.11.048. Epub 2018 Nov 15. PMID: 30448573
Conclusion: In our cohort, SLIC scoring did not adequately predict odds of failure of nonoperative management.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/30448573
60. Malhotra, NR., Piazza, M., Demoor, R., McClintock, SD., Hamilton, K., Sharma, N., Osiemo, B., Berger, I., Hossain, E., Borovskiy, Y., Maloney, E., Smith, LJ., Grady, MS. Impact of Reduced Preincision Antibiotic Infusion Time on Surgical Site Infection Rates: A Retrospective Cohort Study. Ann Surg. 2020 Apr;271(4):774-780. doi: 10.1097/SLA.0000000000003030. PMID: 30169395
Conclusion: The retrospective data here suggest a critical infusion time for infection reduction (24.6 min before incision). Prospective implementation of an algorithm led to 100% compliance.
Pubmed link: https://www.ncbi.nlm.nih.gov/pubmed/30169395
61. Goel, NJ., Agarwal, P., Mallela, AN., Abdullah, KG., Ali, ZS., Ozturk, AK., Malhotra, NR., Schuster, JM., Chen, HI. Liver disease is an independent predictor of poor 30-day outcomes following surgery for degenerative disease of the cervical spine. Spine J. 2019 Mar;19(3):448-460. doi: 10.1016/j.spinee.2018.07.010. Epub 2018 Jul 24. PMID: 30053522
Conclusion: Liver disease independently predicts poor perioperative outcome following surgery for degenerative disease of the cervical spine.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/30053522
62. Piazza, M., Sharma, N., Osiemo, B., McClintock, S., Missimer, E., Gardiner, D., Maloney, E., Callahan, D., Smith, JL., Welch, W., Schuster, J., Grady, MS., Malhotra, NR. Initial Assessment of the Risk Assessment and Prediction Tool in a Heterogeneous Neurosurgical Patient Population. Neurosurgery. 2019 Jul 1;85(1):50-57. doi: 10.1093/neuros/nyy197. PMID: 29788192
Conclusion: Our analysis identified age, lower lumbar/lumbosacral surgery, and RAPT walk score as independent predictors of discharge to SNF, and demonstrated superior predictive power compared with the total RAPT Score when combined in a novel grading scale.
Pubmed link: https://www.ncbi.nlm.nih.gov/pubmed/29788192
63. Piazza M., Peck SH., Gullbrand SE., Bendigo JR., Arginteanu T., Zhang Y., Smith HE., Malhotra NR., Smith LJ. Quantitative MRI correlates with histological grade in a percutaneous needle injury mouse model of disc degeneration. J Orthop Res. 2018 Oct;36(10):2771-2779. doi: 10.1002/jor.24028. Epub 2018 May 24. PMID: 29687490
Conclusion: In this study, we demonstrated that quantitative MRI can detect disc degeneration in the mouse caudal spine 4 weeks following percutaneous needle injury and may therefore serve as a surrogate for histology in longitudinal studies of both disc degeneration and cell-based therapies for disc regeneration using this model.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/29687490
64. Nayak NR., Piazza M., Milby A., Thawani JP., Smith LJ., Stein SC., Malhotra NR. Surgical Approaches for the Treatment of Multilevel Cervical Ossification of the Posterior Longitudinal Ligament: Results of a Decision Analysis. World Neurosurg. 2018 Apr;112:e375-e384. doi: 10.1016/j.wneu.2018.01.051. Epub 2018 Jan 31. PMID: 29355800
Conclusion: The results suggest that owing to the higher rates of complications associated with anterior cervical approaches, laminoplasty may result in improved long-term outcomes from an HRQoL standpoint.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/29355800
65. Nayak NR, Richard CE, Martinez-Lage M, Smith H, Malhotra NR. Synovial-type giant cell tumors of the axial spine. J Neurosurg Sci. 2017 Feb;61(1):106-109. PMID: 26868266
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/26868266/
66. Pisapia JM, Nayak NR, Salinas RD, Macyszyn L, Lee JY, Lucas TH, Malhotra NR, Isaac Chen H, Schuster JM. Navigated odontoid screw placement using the O-arm: technical note and case series. J Neurosurg Spine. 2017 Jan;26(1):10-18. PMID: 27517526
Conclusion: The results suggest that O-arm-assisted odontoid screw fixation is a viable approach for odontoid process fractures
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/27517526/
67. Tong W, Lu Z, Qin L, Mauck RL, Smith HE, Smith LJ, Malhotra NR, Heyworth MF, Caldera F, Enomoto-Iwamoto M, Zhang Y. Cell therapy for the degenerating intervertebral disc. Transl Res. 2017 Mar;181:49-58. PMID: 27986604
Conclusion: Hydrogel scaffolds may prevent cell leakage and provide biomechanical support until cells can become established matrix producers.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/27986604/
68. Jiang X, Orton M, Feng R, Hossain E, Malhotra NR, Zager EL, Liu R. Chronic Opioid Usage in Surgical Patients in a Large Academic Center. Ann Surg. 2017 Apr;265(4):722-727. PMID: 27163960
Conclusion:
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/27163960/
69. Nayak NR, Bauman JA, Stein SC, Thawani JP, Malhotra NR. Surgical Approaches for the Treatment of Thoracic Disk Herniation: Results of a Decision Analysis. Clin Spine Surg. 2017 Aug;30(7):E901-E908. PMID: 27018910
Conclusion: Overall prevalence of chronic opioid usage in surgical patients is high with widespread disparity among different sex, age, ethnicity, BMI, and subspecialty groups. Information obtained from this study provides clues to reduce chronic opioid usage in surgical patients.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/27018910/
70. Ali ZS., Ma TS., Ozturk AK., Malhotra NR., Schuster JM., Marcotte PJ., Grady MS., Welch WC. Pre-optimization of spinal surgery patients: Development of a neurosurgical enhanced recovery after surgery (ERAS) protocol. Clin Neurol Neurosurg. 2018 Jan;164:142-153. doi: 10.1016/j.clineuro.2017.12.003. Epub 2017 Dec 8. PMID: 29232645
Conclusion: The present proposal aims to provide supporting data for the application of these specific ERAS components in the spine surgery population and provide rationale/justification of this type of care pathway.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/29232645
71. Peck SH., McKee KK., Tobias JW., Malhotra NR., Harfe BD., Smith LJ. Whole Transcriptome Analysis of Notochord-Derived Cells during Embryonic Formation of the Nucleus Pulposus. Sci Rep. 2017 Sep 5;7(1):10504. PMID: 28874804
Conclusion: These results suggest that signaling and biosynthesis of embryonic notochord-derived cells (NDCs) change dramatically as a function of developmental stage; important as recapitulation of developmental signals represents a promising strategy for treating intervertebral disc degeneration.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/28874804/
72. Hitti FL., Hudgins ED., Chen HI., Malhotra NR., Zager EL., Schuster JM. Intraoperative Navigation Is Associated with Reduced Blood Loss During C1-C2 Posterior Cervical Fixation. World Neurosurg. 2017 Nov;107:574-578. PMID: 28842229
Conclusion: Our results suggest that surgical navigation significantly reduced blood loss compared with non-navigated cases without increasing surgical time or risk of complication.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/28842229/
73. Gullbrand SE., Schaer TP., Agarwal P., Bendigo JR., Dodge GR., Chen W., Elliott DM., Mauck RL., Malhotra NR., Smith LJ. Translation of an injectable triple-interpenetrating-network hydrogel for intervertebral disc regeneration in a goat model. Acta Biomater. 2017 Sep 15;60:201-209. PMID: 28735027
Conclusion: These results support evaluation of this hydrogel as a minimally invasive disc therapeutic in long-term preclinical studies as a precursor to future clinical application in patients with disc degeneration and low back pain.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/28735027/
74. Piazza M., Nayak N., Ali Z., Heuer G., Sanborn M., Stein S., Schuster J., Grady MS., Malhotra NR. Trends in Resident Operative Teaching Opportunities for Treatment of Intracranial Aneurysms. World Neurosurg. 2017 Jul;103:194-200. PMID: 28377249
Conclusion: Our results suggest a significant decrease in opportunity for operative exposure to craniotomy for ruptured aneurysm clipping over the past decade, whereas the volume of endovascular procedures for aneurysms has dramatically increased, highlighting the need for a shift in training strategy for those neurosurgeons graduating from residency desiring to subspecialize in neurovascular neurosurgery.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/28377249/
75. Berger I., Nayak N., Schuster J., Lee J., Stein S., Malhotra NR. Microvascular Decompression Versus Stereotactic Radiosurgery for Trigeminal Neuralgia: A Decision Analysis. Cureus. 2017 Jan 26;9(1):e1000. PMID: 28280653
Conclusion: With a decision-analytic model, we calculated that microvascular decompression (MVD) provides more favorable outcomes than stereotactic radiosurgery (SRS) for the treatment of trigeminal neuralgia.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/28280653/
76. Nayak NR, Stephen JH, Abdullah KG, Stein SC, Malhotra NR. Comparing Utility Scores in Common Spinal Radiculopathies: Results of a Prospective Valuation Study. Global Spine J. 2016 May;6(3):270-6. PMID: 27099818
Conclusion: Utility values associated with the most common levels of cervical and lumbar radiculopathy do not significantly differ from each other, validating the current practice of grouping utility by spinal segment rather than by specific root levels.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/27099818/
77. Malhotra NR, Lewis D, Attiah M, Burnett M, Stein S. To the Editor. Spine (Phila Pa 1976). 2016 Feb;41(3):E185. PMID: 26866745
Conclusion: Anterior cervical discectomy (ACD) without fusion is not frequently performed in the United States but is common practice in many parts of the world. As we begin to consider value in healthcare, alternative approaches must be either validated for further study, or refuted.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/26866745/
78. Peck SH, Casal ML, Malhotra NR, Ficicioglu C, Smith LJ. Pathogenesis and treatment of spine disease in the mucopolysaccharidoses. Mol Genet Metab. 2016 Aug;118(4):232-43. PMID: 27296532
Conclusion: In this study, we reviewed current understanding of the underlying pathophysiology of spine disease in mucopolysaccharidoses (MPS), how the tissues of the spine respond to current clinical and experimental treatments, and discuss future strategies for improving the efficacy of these treatments
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/27296532/
79. Gullbrand SE, Malhotra NR, Schaer TP, Zawacki Z, Martin JT, Bendigo JR, Milby AH, Dodge GR, Vresilovic EJ, Elliott DM, Mauck RL, Smith LJ. A large animal model that recapitulates the spectrum of human intervertebral disc degeneration. Osteoarthritis Cartilage. 2017 Jan;25(1):146-156. PMID: 27568573
Conclusion: A large animal model of disc degeneration was established that recapitulates the spectrum of structural, compositional and biomechanical features of human disc degeneration, a model that may serve as a robust platform for evaluating the efficacy of therapeutics targeted towards varying degrees of disc degeneration.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/27568573/
80. Agarwal P, Burke JF, Abdullah KG, Piazza M, Smith BP, Thawani JP, Malhotra NR. Stab wound to the intramedullary spinal cord: Presurgical and surgical management options for a retained blade to optimize neurological preservation. Surg Neurol Int. 2016 Dec 26;7(Suppl 42):S1096-S1098. PMID: 28144493
Conclusion: The surgical management of NMPSI in patients who are neurologically intact is controversial. Here, we report surgical excision of a knife that penetrated the spinal cord at the T11 level, without the patient incurring further neurological deterioration.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/28144493/
81. Gorth DJ, Lothstein KE, Chiaro JA, Farrell MJ, Dodge GR, Elliott DM, Malhotra NR, Mauck RL, Smith LJ. Hypoxic regulation of functional extracellular matrix elaboration by nucleus pulposus cells in long-term agarose culture. J Orthop Res. 2015 May;33(5):747-54. PMID: 25640328
Conclusion: Culture under physiological oxygen levels is an important consideration for successful development of cell and growth factor-based regenerative strategies for the disc.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/25640328/
82. Showalter BL, Elliott DM, Chen W, Malhotra NR. Evaluation of an In Situ Gelable and Injectable Hydrogel Treatment to Preserve Human Disc Mechanical Function Undergoing Physiologic Cyclic Loading Followed by Hydrated Recovery. J Biomech Eng. 2015 Aug;137(8):081008. PMID: 25950273
Conclusion: Implant interdigitates with the nucleus pulposus, preventing its expulsion during 10,000 cycles of compressive loading and preserves disc creep within human L5-S1 discs. This and previous studies provide a solid foundation for continuing to evaluate the efficacy of the hydrogel implant.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/25950273/
83. Whitmore RG, Curran JN, Ali ZS, Mummaneni PV, Shaffrey CI, Heary RF, Kaiser MG, Asher AL, Malhotra NR, Cheng JS, Hurlbert J, Smith JS, Magge SN, Steinmetz MP, Resnick DK, Ghogawala Z. Predictive value of 3-month lumbar discectomy outcomes in the NeuroPoint-SD Registry. J Neurosurg Spine. 2015 Oct;23(4):459-66. PMID: 26140406
Conclusion: This national spine registry demonstrated successful collection of high-quality outcomes data for spinal procedures in actual practice, providing a practical foundation for the acquisition of outcome data following lumbar discectomy.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/26140406/
84. Peck SH, O'Donnell PJ, Kang JL, Malhotra NR, Dodge GR, Pacifici M, Shore EM, Haskins ME, Smith LJ. Delayed hypertrophic differentiation of epiphyseal chondrocytes contributes to failed secondary ossification in mucopolysaccharidosis VII dogs. Mol Genet Metab. 2015 Nov;116(3):195-203. PMID: 26422116
Conclusion: Failed vertebral bone formation in MPS VII can be traced to the failure of epiphyseal chondrocytes to undergo hypertrophic differentiation at the appropriate developmental stage and suggest that aberrant processing of Sox9 protein may contribute to this cellular dysfunction.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/26422116/
85. Nayak NR, Coats JM, Abdullah KG, Stein SC, Malhotra NR. Tracking patient-reported outcomes in spinal disorders. Surg Neurol Int. 2015 Oct 8;6(Suppl 19):S490-9. PMID: 26605111
Conclusion: While a number of PROMs are available for tracking outcomes in spine surgery, only a handful appear to be widely used. At least one instrument from each category should be measured pre- and post-operatively to quantify treatment effect.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/26605111/
86. Stein SC, Malhotra NR, Burnett MG. Letter to the Editor: Cost-effectiveness analysis. J Neurosurg Spine. 2014 Apr;20(4):474. PMID: 24527823
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/24527823/
87. Smith LJ, Gorth DJ, Showalter BL, Chiaro JA, Beattie EE, Elliott DM, Mauck RL, Chen W, Malhotra NR. In vitro characterization of a stem-cell-seeded triple-interpenetrating-network hydrogel for functional regeneration of the nucleus pulposus. Tissue Eng Part A. 2014 Jul;20(13-14):1841-9. PMID: 24410394
Conclusion: Collectively, our results establish the therapeutic potential of a novel hydrogel for functional regeneration of the nucleus pulposus (NP).
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/24410394/
88. Malhotra NR, Kosty J, Sanborn M, Bekisz JM, Mooncai TW, Neustein TM, Ou J, Zhu A, Bernstein A, Stein SC. Optimal approach to circumferential decompression and reconstruction for thoracic spine metastatic disease. Ann Surg Oncol. 2014 Sep;21(9):2864-72. PMID:
Conclusion: Using a decision-analytic model, we found no significant difference in QOL resulting from anterior versus posterior approaches to metastatic lesions in the thoracic spine; decisions should instead be based on surgeon comfort, tumor characteristics, anatomy of the lesion, patient-related factors, and goals of the operation.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/24728819/
89. Mummaneni PV, Whitmore RG, Curran JN, Ziewacz JE, Wadhwa R, Shaffrey CI, Asher AL, Heary RF, Cheng JS, Hurlbert RJ, Douglas AF, Smith JS, Malhotra NR, Dante SJ, Magge SN, Kaiser MG, Abbed KM, Resnick DK, Ghogawala Z. Cost-effectiveness of lumbar discectomy and single-level fusion for spondylolisthesis: experience with the NeuroPoint-SD registry. Neurosurg Focus. 2014 Jun;36(6):E3. PMID: 24881635
Conclusion: This national spine registry demonstrated successful collection of high-quality outcomes data for spinal procedures in actual practice. This work sets the stage for real-world analysis of the value of health interventions.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/24881635/
90. Lang SS, Chen HI, Koch MJ, Kurash L, McGill-Armento KR, Palella JM, Stein SC, Malhotra NR. Development of an outpatient protocol for lumbar discectomy: our institutional experience. World Neurosurg. 2014 Nov;82(5):897-901. PMID: 24907436
Conclusion: Our data demonstrate that a collaborative protocol for outpatient discectomy can be implemented in a safe and effective manner despite a statistical increase in hospital readmissions.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/24907436/
91. Showalter BL, Malhotra NR, Vresilovic EJ, Elliott DM. Nucleotomy reduces the effects of cyclic compressive loading with unloaded recovery on human intervertebral discs. J Biomech. 2014 Aug 22;47(11):2633-40. PMID: 24957922
Conclusion: Results of this study provide an ideal protocol and control data for evaluating the effectiveness of a mechanically-based disc degeneration treatment, such as a nucleus replacement.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/24957922/
92. Gorth DJ, Martin JT, Dodge GR, Elliott DM, Malhotra NR, Mauck RL, Smith LJ. In vivo retention and bioactivity of IL-1ra microspheres in the rat intervertebral disc: a preliminary investigation. J Exp Orthop. 2014 Dec;1(1):15. PMID: 26914760
Conclusion: Microspheres can successfully be delivered to the disc in vivo and retained for a clinically relevant time frame. IL-1ra released from microspheres can effectively prevent IL-1β-induced NP glycosaminoglycan loss in vivo.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/26914760/
93. Chiaro JA, O'Donnell P, Shore EM, Malhotra NR, Ponder KP, Haskins ME, Smith LJ. Effects of neonatal enzyme replacement therapy and simvastatin treatment on cervical spine disease in mucopolysaccharidosis I dogs. J Bone Miner Res. 2014 Dec;29(12):2610-7. PMID: 24898323
Conclusion: These results indicate that ERT begun from a very early age attenuates the severity of cervical spine disease in MPS I, particularly for the vertebral bone and odontoid process, and that additional treatment with simvastatin does not provide a significant additional benefit over ERT alone.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/24898323/
94. Lewis DJ, Attiah MA, Malhotra NR, Burnett MG, Stein SC. Anterior surgical management of single-level cervical disc disease: a cost-effectiveness analysis. Spine (Phila Pa 1976). 2014 Dec 1;39(25):2084-92. PMID: 25271510
Conclusion: Anterior cervical discectomy without fusion (ACD) is a cost-effective alternative to anterior cervical discectomy with fusion and cervical disc replacemen (CDR) in patients with single-level cervical disc disease.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/25271510/
95. Chen HI, Lang SS, Coyne TM, Malhotra NR, Schuster JM. Intramedullary spinal sarcoidosis masquerading as cervical stenosis. World Neurosurg. 2013 Dec;80(6):e375-80. PMID: 23041066
Conclusion: Spinal sarcoidosis can mimic more common disease processes, such as cervical spondylosis. It is an important consideration in the diagnosis of intramedullary or intradural lesions of the spinal cord because early medical treatment may improve the course of the disease process.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/23041066/
96. Clement RC, Carr BG, Kallan MJ, Wolff C, Reilly PM, Malhotra NR. Volume-outcome relationship in neurotrauma care. J Neurosurg. 2013 Mar;118(3):687-93. PMID: 23240697
Conclusion: A volume-outcome relationship (VOR) exists in the treatment of neurotrauma, and a meaningful threshold for significantly improved mortality is 6 cases per year. Emergency and interfacility transport policies based on this threshold might improve national outcomes
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/23240697/
97. Syre P, Petrov D, Malhotra NR. Management of upper cervical spine injuries: a review. J Neurosurg Sci. 2013 Sep;57(3):219-40. PMID: 23877268
Conclusion: We present these common injuries found in the occipital-atlantoaxial complex and their management based on the current and historical literature.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/23877268/
98. Ghogawala Z, Shaffrey CI, Asher AL, Heary RF, Logvinenko T, Malhotra NR, Dante SJ, Hurlbert RJ, Douglas AF, Magge SN, Mummaneni PV, Cheng JS, Smith JS, Kaiser MG, Abbed KM, Sciubba DM, Resnick DK. The efficacy of lumbar discectomy and single-level fusion for spondylolisthesis: results from the NeuroPoint-SD registry: clinical article. J Neurosurg Spine. 2013 Nov;19(5):555-63. PMID: 24010898
Conclusion: It is feasible to build a national spine registry for the collection of high-quality prospective data to demonstrate the effectiveness of spinal procedures in actual practice.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/24010898/
99. Syre P 3rd, Rodriguez-Cruz L, Desai R, Greene KA, Hurst R, Schuster J, Malhotra NR, Marcotte P. Civilian gunshot wounds to the atlantoaxial spine: a report of 10 cases treated using a multidisciplinary approach. J Neurosurg Spine. 2013 Dec;19(6):759-66. PMID: 24053375
Conclusion: Unilateral gunshot wounds to the atlantoaxial complex are usually stable and the need for acute surgical intervention is rare. Unilateral vertebral artery injury is well tolerated, and any information provided by angiography does not alter the acute management of the patient. Vascular complications from gunshot wounds can be managed effectively by endovascular techniques.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/24053375/
100. Sanborn MR, Thawani JP, Whitmore RG, Shmulevich M, Hardy B, Benedetto C, Malhotra NR, Marcotte P, Welch WC, Dante S, Stein SC. Cost-effectiveness of confirmatory techniques for the placement of lumbar pedicle screws. Neurosurg Focus. 2012 Jul;33(1):E12. PMID: 22746229
Conclusion: Use of the O-arm for confirming pedicle screw placement is the least costly and therefore most cost-effective strategy of the 3 techniques analyzed.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/22746229/
101. Malhotra NR, Han WM, Beckstein J, Cloyd J, Chen W, Elliott DM. An injectable nucleus pulposus implant restores compressive range of motion in the ovine disc. Spine (Phila Pa 1976). 2012 Aug 15;37(18):E1099-105. PMID: 22588378
Conclusion: An injectable implant that mimics nondegenerate nucleus pulposus (NP) has the potential to return motion segment ROM to normal subsequent to injury.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/22588378/
102. O'Connell GD, Malhotra NR, Vresilovic EJ, Elliott DM. The effect of nucleotomy and the dependence of degeneration of human intervertebral disc strain in axial compression. Spine (Phila Pa 1976). 2011 Oct 1;36(21):1765-71. PMID: 21394074
Conclusion: Nucleotomy alters the internal radial and axial AF strains in the neutral position, which may leave the AF vulnerable to damage and microfractures. Some of the nucleotomy effects are modulated by degeneration, where the mechanical effect of nucleotomy was magnified in degenerated discs and may further induce mechanical damage and degeneration.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/21394074/
103. Lega BC, Danish SF, Malhotra NR, Sonnad SS, Stein SC. Choosing the best operation for chronic subdural hematoma: a decision analysis. J Neurosurg. 2010 Sep;113(3):615-21. PMID: 19877806
Conclusion: Bur-hole craniostomy is the most efficient choice for surgical drainage of uncomplicated CSDH. Bur-hole craniostomy balances a low recurrence rate with a low incidence of highly morbid complications.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/19877806/
104. Malhotra NR, Shaffrey CI. Intraoperative electrophysiological monitoring in spine surgery. Spine (Phila Pa 1976). 2010 Dec 1;35(25):2167-79. PMID: 21102290
Conclusion: As spine surgery, and patient comorbidity, becomes increasingly complex, IOM permits more aggressive deformity correction and tumor resection.
Pubmed link: https://pubmed.ncbi.nlm.nih.gov/21102290/
105. Espinoza Orías AA, Malhotra NR, Elliott DM. Rat disc torsional mechanics: effect of lumbar and caudal levels and axial compression load. Spine J. 2009 Mar;9(3):204-9. PMID: 18495544
Conclusion: Use of the caudal disc as a model may be appropriate if the mechanical focus is within the linear region of the loading regime, providing support for use of this animal model in basic science studies with respect to torsional mechanics
Pubmed Link: https://pubmed.ncbi.nlm.nih.gov/18495544/
106. Chen HI, Malhotra NR, Oddo M, Heuer GG, Levine JM, LeRoux PD. Barbiturate infusion for intractable intracranial hypertension and its effect on brain oxygenation. Neurosurgery. 2008 Nov;63(5):880-6; discussion 886-7. PMID: 19005378
Conclusion: Pentobarbital administered for intractable intracranial hypertension is associated with a significant and independent increase in PbtO2 in the majority of patients. In some patients with more compromised brain physiology, pentobarbital may have a negative effect on PbtO2, however, particularly if administered late.
Pubmed Link: https://pubmed.ncbi.nlm.nih.gov/19005378/
107. Cloyd JM, Malhotra NR, Weng L, Chen W, Mauck RL, Elliott DM. Material properties in unconfined compression of human nucleus pulposus, injectable hyaluronic acid-based hydrogels and tissue engineering scaffolds. Eur Spine J. 2007 Nov;16(11):1892-8. PMID: 17661094
Conclusion: The synthetic HA-based hydrogels approximated NP well and may serve as suitable NP implant materials.
Pubmed Link: https://pubmed.ncbi.nlm.nih.gov/17661094/
108. Gaston B, Ratjen F, Vaughan JW, Malhotra NR, Canady RG, Snyder AH, Hunt JF, Gaertig S, Goldberg JB. Nitrogen redox balance in the cystic fibrosis airway: effects of antipseudomonal therapy. Am J Respir Crit Care Med. 2002 Feb 1;165(3):387-90. PMID: 11818326
Conclusion: We conclude that treatment of pseudomonal lung infections is associated with decreased NH(4)(+) concentrations in the CF airways. In epithelial cells, NH(4)(+) inhibits chloride transport, and nitrogen oxides inhibit amiloride-sensitive sodium transport and augment chloride transport.
Pubmed Link: https://pubmed.ncbi.nlm.nih.gov/11818326/
109. Glauser, G., Detchou, DK., Dimentberg, R., Ramayya, AG., Malhotra, NR. Social Determinants of Health and Neurosurgical Outcomes: Current State and Future Directions. Neurosurgery (in press)
110. Farooqi, A., Detchou, DK., Glauser, G., Strouz, K., McClintock, SD., Malhotra, NR. Overlapping Single-Level Lumbar Fusion and Adverse Short-Term Outcomes. Journal of Neurosurgery: Spine. (in press)
111. Huang, V., Miranda, SP., Dimentberg, R., Glauser, G., Shultz, K., McClintock, SD., Malhotra, NR. The Role of Socioeconomic Status on Outcomes Following Cerebellopontine Angle Tumor Resection. British Journal of Neurosurgery. (in press)
112. Farooqi, A., Detchou, DK., Glauser, G., Strouz, K., McClintock, SD., Malhotra, NR. Gender is Associated with Long-Term Mortality After Cerebellopontine Angle Tumor Resection. Clinical Neurology and Neurosurgery. (in press)
PubMed Link: https://pubmed.ncbi.nlm.nih.gov/33422925/
113. Winter E, Hynes AM, Shultz K, Holena DN, Malhotra NR, Cannon JW. Association of Police Transport With Survival Among Patients With Penetrating Trauma in Philadelphia, Pennsylvania. JAMA Netw Open. 2021 Jan 4;4(1):e2034868. doi: 10.1001/jamanetworkopen.2020.34868. PMID: 33492375.
Pubmed Link: https://pubmed.ncbi.nlm.nih.gov/33492375/
Articles in Process / Upcoming Publications
114. Arginteanu, T., Glauser, G., Smith, LJ., Pasha, S., DeTurck, D., Malhotra, NR. Quantifying Scoliosis Severity using Differential Geometry. International Journal of Spine Surgery.
115. Haldar, D., Glauser, G., Winter, E., Dimentberg, R., Goodrich, S., Shultz, K., McClintock, SD., Malhotra, NR. The Influence of Race on Outcomes Following Pituitary Tumor Resection. Clinical Neurology and Neurosurgery.
116. Sinha, S., Glauser, G., Kvint, S., Ramayya, AG., Vaughan, K., Dimentberg, R., Malhotra, NR., Marcotte, PJ. The Intertransverse Approach for Far Lateral Lumbar Disc Herniation: Case Series of 63 Patients and Review of the Literature. Asian J Neurosurg.
117. Farooqi, A., Dimentberg, R., Glauser, G., Shultz, K., McClintock, SD., Malhotra, NR. The Impact of Gender on Long-Term Outcomes Following Supratentorial Brain Tumor Resection. British Journal of Neurosurgery. In revision.
118. Howard, S., Kvint, S., Dimentberg, R., Shultz, K., McClintock, SD., Malhotra, NR. Social Determinants of Health: Patient Gender and Meningioma Resection Outcomes. Clinical Neurology and Neurosurgery
119. Spadola, M., Farooqi, A., Dimentberg R., Blue, R., Shultz, K., McClintock, SD., Malhotra, NR. The Impact of Household Income on 30-Day Outcomes Following Supratentorial Meningioma Resection. Neurochirurgie.
120. Huang, V., Miranda, SP., Dimentberg, R., Shultz, K., McClintock, SD., Malhotra, NR. Effect of Household Income on Short-Term Outcomes Following Cerebellopontine Angle Tumor Resection. J Neurol Surg B Skull Base.
121. Detchou, DK., Glauser, G., Dimentberg, R., Schuster, JM., Malhotra, NR. Case Series of Ultrasonic Navigated Osteotomy for the Treatment of Chordomas. World Neurosurgery.
122. Glauser, G., Sharma, N., Amendolia, O., Cimoch, J., Callahan, D., Durkan, J., Hoke, N., Maloney, E., Grady, MS., Malhotra, NR. Performance Improvement in Action: Quality Initiative for the Administration of Vancomycin Prophylaxis in Penicillin Allergic Neurosurgery Patients. Journal of Neuroscience Nursing.
123. Farooqi, A., Detchou, DK., Glauser, G., Strouz, K., McClintock, SD., Malhotra, NR. Gender is Associated with Long-Term Mortality After Cerebellopontine Angle Tumor Resection. Clinical Neurology and Neurosurgery. In revision.
124. Farooqi, A., Detchou, DK., Glauser, G., Strouz, K., McClintock, SD., Malhotra, NR. Increasing Nonconcurrent Overlap is not Associated with Outcome Changes in Lumbar Fusion. Neurosurgery. In revision.
125. Connolly, J., Borja, AJ., Kvint. S, Detchou, DK., Glauser, G., Shultz, K., McClintock, SD., Marcotte, PJ., Malhotra, NR. Open Versus Minimally Invasive Endoscopic Approaches for Treatment of Far Lateral Disc Herniations. World Neurosurgery.
126. Borja, AJ., Connolly, J., Kvint. S, Detchou, DK., Glauser, G., Shultz, K., McClintock, SD., Marcotte, PJ., Malhotra, NR. Charlson Comorbidity Index Score Is Associated with 90-Day Return to Surgery Following Endoscopic Discectomy for Far Lateral Disc Herniation. Irish Journal of Medical Sciences.
127. Connolly, J., Borja, AJ., Kvint. S, Detchou, DK., Glauser, G., Strouz, K., McClintock, SD., Marcotte, PJ., Malhotra, NR. Binary STOP-Bang Score is not Associated with Adverse Outcomes Following Endoscopic Discectomy for Far Lateral Disc Herniation. Asian J Neurosurg.
128. Connolly, J., Borja, AJ., Kvint. S, Detchou, DK., Glauser, G., Strouz, K., McClintock, SD., Marcotte, PJ., Malhotra, NR. Outcomes of Endoscopic Discectomy for Far Lateral Disc Herniation are not Predicted by Undiagnosed Obstructive Sleep Apnea. Journal of Neurological Surgery Part A: Central European Neurosurgery.
129. Connolly, J., Borja, AJ., Kvint. S, Detchou, DK., Glauser, G., Strouz, K., McClintock, SD., Marcotte, PJ., Malhotra, NR. Undiagnosed Obstructive Sleep Apnea is not Associated with Adverse Outcomes Following Open Discectomy for Far Lateral Disc Herniation. Neurologia medico-chirurgica.
130. Borja, AJ., Connolly, J., Kvint. S, Detchou, DK., Glauser, G., Strouz, K., McClintock, SD., Marcotte, PJ., Malhotra, NR. Household Income Is Not Predictive of Postsurgical Outcomes Following Endoscopic Discectomy for Far Lateral Disc Herniation. International Journal of Spine Surgery.
131. Connolly, J., Borja, AJ., Kvint. S, Detchou, DK., Glauser, G., Strouz, K., McClintock, SD., Marcotte, PJ., Malhotra, NR. Binary STOP-Bang Score does not Predict Morbidity and Mortality Following Open Discectomy for Far Lateral Disc Herniation. British Journal of Neurosurgery.
132. Borja, AJ., Connolly, J., Kvint. S, Detchou, DK., Glauser, G., Strouz, K., McClintock, SD., Marcotte, PJ., Malhotra, NR. Household Income is Associated with Return to Surgery Following Open Discectomy for Far Lateral Disc Herniation. Journal of Neurosurgical Sciences.
133. Farooqi, AS., Borja, AJ., Detchou, DK., Glauser, G., Shultz, K., McClintock, SD., Malhotra, NR. Overlap Before the Critical Step of Lumbar Fusion Does Not Lead to Increased Short-Term Morbidity. Spine.
134. Farooqi, AS., Borja, AJ., Detchou, DK., Glauser, G., Shultz, K., McClintock, SD., Malhotra, NR. Postoperative Outcomes are Not Affected by Overlap Before or After the Critical Step of Lumbar Fusion. Journal of Neurosurgery: Spine.
135. Farooqi, A., Glauser, G., Detchou, DK., Strouz, K., McClintock, SD., Malhotra, NR. Gender Disparity in Short-Term Patient Outcomes after Cerebellopontine Angle (CPA) Tumor Resection. Journal of Neurological Surgery Part B: Skull Base.
136. Borja, AJ., Connolly, J., Kvint. S, Detchou, DK., Glauser, G., Strouz, K., McClintock, SD., Marcotte, PJ., Malhotra, NR. Charlson Comorbidity Index Score Predicts Adverse Post-Operative Outcomes Following Discectomy for Far Lateral Disc Herniation. Global Spine Journal.
137. Connolly, J., Borja, AJ., Kvint. S, Detchou, DK., Glauser, G., Strouz, K., McClintock, SD., Marcotte, PJ., Malhotra, NR. Outcomes Following Discectomy for Far Lateral Disc Herniation are not Predicted by Binary STOP-Bang Score. Journal of Neurosurgical Sciences.
138. Borja, AJ., Connolly, J., Kvint. S, Detchou, DK., Glauser, G., Strouz, K., McClintock, SD., Marcotte, PJ., Malhotra, NR. Charlson Comorbidity Index Score Predicts Unfavorable Outcomes Following Open Far Lateral Discectomy. Clinical Neurology and Neurosurgery.
139. Borja, AJ., Connolly, J., Kvint. S, Detchou, DK., Glauser, G., Strouz, K., McClintock, SD., Marcotte, PJ., Malhotra, NR. Household Income Predicts 90-Day Return to Surgery Following Discectomy for Far Lateral Disc Herniation. European Spine Journal.
140. Connolly, J., Borja, AJ., Kvint. S, Detchou, DK., Glauser, G., Strouz, K., McClintock, SD., Marcotte, PJ., Malhotra, NR. Undiagnosed Obstructive Sleep Apnea Does Not Predict Adverse Outcomes in Patients Undergoing Discectomy for Far Lateral Disc Herniation. Irish Journal of Medical Sciences.