Accelerator Fund Projects 2016-2017
Measuring the Impact of ctDNA NGS on Clinical Decision Making for NSCLC Patients
Charu Aggarwal, MD
Principal Investigators (PIs):
- Erica L. Carpenter, MBA, PhD
Department of Medicine, Division of Hematology and Oncology - Charu Aggarwal, MD
Department of Medicine, Division of Hematology and Oncology
Co-Investigators (Co-Is):
- Kojo Elenitoba-Johnson, MD
Center for Personalized Diagnostics - Sharyn Katz, MD
MTR Radiology - Corey Langer, MD
Hematology/Oncology - Jennifer Morrissette, PhD
Center for Personalized Diagnostics - Andrea Troxel, ScD
Biostatistics and Epidemiology
A Pharmacogenetic Approach to Parkinson’s Disease
Principal Investigator (PI):
- Alice Chen-Plotkin, MD
Department of Neurology
Co-Investigators (Co-Is):
- Daniel Weintraub, MD
Psychiatry - Vivianna Van Deerlin, MD, PhD
Pathology and Laboratory Medicine - Allison Willis, MD
Department of Neurology
Optimizing Antimicrobial Prescribing Using a Precision Antibiogram
Principal Investigator (PI):
- Keith William Hamilton, MD
Department of Medicine, Division of Infectious Diseases
Co-Investigators (Co-Is):
- Valerie Cluzet, MD
Division of Infectious Diseases - Kevin Alby, PhD
Pathology and Laboratory Medicine
Precision Medicine and Digital Media: Exploring Applications for Clinical Care
Principal Investigator (PI):
- Raina M. Merchant, MD, MSHP, FAHA
Department of Emergency Medicine
Co-Investigators (Co-Is):
- David Asch, MD, MBA
Department of Medicine - David Grande, MD, MPA
Leonard Davis Institute for Health Economics - Lyle Ungar, PhD
Computer and Information Science
PARP Inhibition in Advanced Breast Cancer with non-BRCA-associated Deficient Homologous Recombination
Principal Investigator (PI):
- Payal D. Shah, MD
Department of Medicine, Division of Hematology and Oncology
Co-Investigators (Co-Is):
- Susan M. Domchek, MD
Basser Professor in Oncology - Katherine L. Nathanson, MD
Department of Medicine - Kara Maxwell, MD, PhD
Department of Medicine
Prehabilitation to Improve Postoperative Outcomes and Limit Complications
Principal Investigator (PI):
- Carsten C. Skarke, MD
Department of Medicine and Department of Systems Pharmacology and Translational Therapeutics
Co-Investigators (Co-Is):
- Nalaka Gooneratne, MD, MSs
Department of Medicine - Junxin Li, PhD
Department of Medicine - Greg Grant, PhD
Department of Genetics - Jason H. Moore, PhD
Department of Biostatistics and Epidemiology - Garret A. FitzGerald, MD
Institute for Translational Medicine and Therapeutics (ITMAT) - Elizabeth Mahanna, MD
Department of Anesthesiology and Critical Care - Gwo-Chin Lee, MD
Department of Orthopedics - Yvette Sheline, MD
Department of Psychiatry
Actionable Pharmacogenetic (PGx) Variants in the University of Pennsylvania Health System
Principal Investigator (PI):
- Sony Tuteja, PharmD, MS
Department of Medicine, Division of Translational Medicine and Human Genetics
Co-Investigators (Co-Is):
- Daniel J. Rader, MD
Department of Medicine - Sean Hennessy, PharmD, PhD
Department of Biostatistics and Epidemiology - Peter E. Gabriel, MD, MSE
Department of Radiation Oncology - Katharine Bar, MD
Department of Medicine
UsingT1rho MRI as a Surrogate for Detection of Early Cartilage Degeneration and Guide for Early Intervention in Patellofemoral Pain
Principal Investigator (PI):
- Miltiadis H. Zgonis, MD
Department of Orthopaedic Surgery
Co-Investigators (Co-Is):
- Ravinder Reddy, PhD
Department of Radiology - J. Bruce Kneeland, MD
Department of Radiology