Why Genome Integrity?
Genome integrity is essential for organism survival and for the inheritance of traits to offspring. The maintenance of genome integrity plays a critical role in the prevention of cancer and other age-associated diseases. Genomic instability is caused by DNA damage, aberrant DNA replication or uncoordinated cell division, which can lead to chromosomal aberrations and gene mutations. The Penn Genome Integrity Group brings together laboratories from Penn, the Children's Hospital of Philadelphia, and The Wistar Institute interested in the mechanisms that safeguard the genome, and how failures in these processes impact tissue homeostasis and cancer risk.
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The Highs and the Lows: End-of-Life Care in the U.S.
- PGIG Symposium - Keynote Steve Kowalczykowski
May 9, 2018 - BRB Auditorium & Lobby
DNA Repair: From Fundamental Mechanisms to Human Disease
- PGIG Seminar - Dr. Prasad V. Jallepalli
June 11, 2018 - 3:00 pm in BRB Auditorium
"Surfing the cell cycle with chemical genetics"
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