PUBLICATIONS

2023 PUBLICATIONS

Culkin MC, Bele P, Georges AP, Lopez AJ, Niziolek G, Jacovides CL, Song H, Johnson VE, Kaplan LJ, Smith DH, Pascual JL. Early Post-Traumatic Brain Injury Txa Prevents Blood Brain Barrier Hyperpermeability and Surrogates of Neuroclinical Recovery. J Trauma Acute Care Surg. 2023. Epub 2023/04/12. doi: 10.1097/TA.0000000000003971. PubMed PMID: 37038259.

Kopczynski A, Carteri RB, Rodolphi MS, Oses JP, Portela LO, Geller CA, de Oliveira VG, De Bastiani MA, Strogulski NR, Smith DH, Portela LV. Lower and higher volumes of physical exercise build up brain reserves against memory deficits triggered by a head injury in mice. Exp Neurol. 2023;363:114352. Epub 2023/02/23. doi: 10.1016/j.expneurol.2023.114352. PubMed PMID: 36813223; PMCID: PMC10103909.

Lee EB, Kennedy-Dietrich C, Geddes JF, Nicoll JAR, Revesz T, Smith DH, Stewart W. The perils of contact sport: pathologies of diffuse brain swelling and chronic traumatic encephalopathy neuropathologic change in a 23-year-old rugby union player. Acta Neuropathol. 2023;145(6):847-50. Epub 2023/04/22. doi: 10.1007/s00401-023-02576-y. PubMed PMID: 37086326; PMCID: PMC10175208.

2022 PUBLICATIONS

Smith DH, Burrell JC, Browne KD, Katiyar KS, Ezra MI, Dutton JL, Morand JP, Struzyna LA, Laimo FA, Chen HI, Wolf JA, Kaplan HM, Rosen JM, Ledebur HC, Zager EL, Ali ZS, Cullen DK. Tissue-engineered grafts exploit axon-facilitated axon regeneration and pathway protection to enable recovery after 5-cm nerve defects in pigs. Sci Adv. 2022;8(44):eabm3291. Epub 2022/11/05. doi: 10.1126/sciadv.abm3291. PubMed PMID: 36332027; PMCID: PMC9635828.

Song H, McEwan PP, Ameen-Ali KE, Tomasevich A, Kennedy-Dietrich C, Palma A, Arroyo EJ, Dolle JP, Johnson VE, Stewart W, Smith DH. Concussion leads to widespread axonal sodium channel loss and disruption of the node of Ranvier. Acta Neuropathol. 2022. Epub 2022/09/16. doi: 10.1007/s00401-022-02498-1. PubMed PMID: 36107227.

Lopez AJ, ElSaadani M, Culkin MC, Jacovides CL, Georges AP, Song H, Kaplan LJ, Kumar MA, Smith DH, Pascual JL. Persistent Blunting of Penumbral Leukocyte Mobilization by Beta Blockade Administered for 2 Weeks After TBI. J Surg Res. 2022;280:196-203. Epub 2022/08/23. doi: 10.1016/j.jss.2022.06.069. PubMed PMID: 35994981.

Song H, Chen C, Kelley B, Tomasevich A, Lee H, Dolle JP, Cheng J, Garcia B, Meaney DF, Smith DH. Traumatic brain injury recapitulates developmental changes of axons. Prog Neurobiol. 2022;217:102332. Epub 2022/07/24. doi: 10.1016/j.pneurobio.2022.102332. PubMed PMID: 35870679; PMCID: PMC9454890.

Yang Z, Atiyas Y, Shen H, Siedlik MJ, Wu J, Beard K, Fonar G, Dolle JP, Smith DH, Eberwine JH, Meaney DF, Issadore DA. Ultrasensitive Single Extracellular Vesicle Detection Using High Throughput Droplet Digital Enzyme-Linked Immunosorbent Assay. Nano Lett. 2022;22(11):4315-24. Epub 2022/05/20. doi: 10.1021/acs.nanolett.2c00274. PubMed PMID: 35588529.

Ameen-Ali KE, Bretzin A, Lee EB, Folkerth R, Hazrati LN, Iacono D, Keene CD, Kofler J, Kovacs GG, Nolan A, Perl DP, Priemer DS, Smith DH, Wiebe DJ, Stewart W, Investigators C-T. Detection of astrocytic tau pathology facilitates recognition of chronic traumatic encephalopathy neuropathologic change. Acta Neuropathol Commun. 2022;10(1):50. Epub 2022/04/13. doi: 10.1186/s40478-022-01353-4. PubMed PMID: 35410438; PMCID: PMC8996534.

Mayer AR, Ling JM, Patton DA, Stephenson DD, Dodd AB, Dodd RJ, Rannou-Latella JG, Smith DH, Johnson VE, Cullen DK, Meier TB, Kinsler RE. Non-Linear Device Head Coupling and Temporal Delays in Large Animal Acceleration Models of Traumatic Brain Injury. Ann Biomed Eng. 2022;50(6):728-39. Epub 2022/04/04. doi: 10.1007/s10439-022-02953-w. PubMed PMID: 35366746; PMCID: PMC9079018.

Strogulski NR, Stefani MA, Bohmer AE, Hansel G, Rodolphi MS, Kopczynski A, de Oliveira VG, Stefani ET, Portela JV, Schmidt AP, Oses JP, Smith DH, Portela LV. Cerebrospinal fluid purinomics as a biomarker approach to predict outcome after severe traumatic brain injury. J Neurochem. 2022;161(2):173-86. Epub 2022/02/15. doi: 10.1111/jnc.15590. PubMed PMID: 35157328; PMCID: PMC9035090.

Lopez AJ, ElSaadani M, Jacovides CL, George A, Culkin MC, Ahmed S, Kumar MA, Kaplan LJ, Smith DH, Pascual JL. Beta blockade in TBI: Dose-dependent reductions in BBB leukocyte mobilization and permeability in vivo. J Trauma Acute Care Surg. 2022;92(5):781-91. Epub 2022/01/20. doi: 10.1097/TA.0000000000003537. PubMed PMID: 35045056; PMCID: PMC9038675.

Smith DH, Rogers J, Dolle JP, Wedel M. Giraffes vs. blue whales vs. dinosaurs: contest reveals which one builds its nervous system fastest to evade predators. Scientific American. 2022.

2021 PUBLICATIONS

LaPlaca MC, Huie JR, Alam HB, Bachstetter AD, Bayir H, Bellgowan PF, Cummings D, Dixon CE, Ferguson AR, Ferland-Beckham C, Floyd CL, Friess SH, Galanopoulou AS, Hall ED, Harris NG, Hawkins BE, Hicks RR, Hulbert LE, Johnson VE, Kabitzke PA, Lafrenaye AD, Lemmon VP, Lifshitz CW, Lifshitz J, Loane DJ, Misquitta L, Nikolian VC, Noble-Haeusslein LJ, Smith DH, Taylor-Burds C, Umoh N, Vovk O, Williams AM, Young M, Zai LJ. Pre-Clinical Common Data Elements for Traumatic Brain Injury Research: Progress and Use Cases. J Neurotrauma. 2021;38(10):1399-410. Epub 2020/12/11. doi: 10.1089/neu.2020.7328. PubMed PMID: 33297844; PMCID: PMC8082734.

Dams-O'Connor K, Bellgowan PSF, Corriveau R, Pugh MJ, Smith DH, Schneider JA, Whitaker K, Zetterberg H. Alzheimer's Disease-Related Dementias Summit 2019: National Research Priorities for the Investigation of Traumatic Brain Injury as a Risk Factor for Alzheimer's Disease and Related Dementias. J Neurotrauma. 2021;38(23):3186-94. Epub 2021/10/30. doi: 10.1089/neu.2021.0216. PubMed PMID: 34714152; PMCID: PMC8820282.

ElSaadani M, Ahmed SM, Jacovides C, Lopez A, Johnson VE, Kaplan LJ, Schwab CW, Smith DH, Pascual JL. Antithrombin III ameliorates post-traumatic brain injury cerebral leukocyte mobilization enhancing recovery of blood brain barrier integrity. J Trauma Acute Care Surg. 2021;90(2):274-80. Epub 2020/10/24. doi: 10.1097/TA.0000000000003000. PubMed PMID: 33093292; PMCID: PMC8878290.

Mayer AR, Dodd AB, Ling JM, Stephenson DD, Rannou-Latella JG, Vermillion MS, Mehos CJ, Johnson VE, Gigliotti AP, Dodd RJ, Chaudry IH, Meier TB, Smith DH, Bragin DE, Lai C, Wagner CL, Guedes VA, Gill JM, Kinsler R. Survival Rates and Biomarkers in a Large Animal Model of Traumatic Brain Injury Combined With Two Different Levels of Blood Loss. Shock. 2021;55(4):554-62. Epub 2020/09/04. doi: 10.1097/SHK.0000000000001653. PubMed PMID: 32881755; PMCID: PMC8112147.

Kant A, Johnson VE, Arena JD, Dolle JP, Smith DH, Shenoy VB. Modeling links softening of myelin and spectrin scaffolds of axons after a concussion to increased vulnerability to repeated injuries. Proc Natl Acad Sci USA. 2021;118(28). Epub 2021/07/09. doi: 10.1073/pnas.2024961118. PubMed PMID: 34234016; PMCID: PMC8285893.

Smith DH, Kochanek PM, Rosi S, Meyer R, Ferland-Beckham C, Prager EM, Ahlers ST, Crawford F. Roadmap for Advancing Pre-Clinical Science in Traumatic Brain Injury. J Neurotrauma. 2021;38(23):3204-21. Epub 2021/07/03. doi: 10.1089/neu.2021.0094. PubMed PMID: 34210174; PMCID: PMC8820284.

Mayer AR, Ling JM, Dodd AB, Rannou-Latella JG, Stephenson DD, Dodd RJ, Mehos CJ, Patton DA, Cullen DK, Johnson VE, Pabbathi Reddy S, Robertson-Benta CR, Gigliotti AP, Meier TB, Vermillion MS, Smith DH, Kinsler R. Reproducibility and Characterization of Head Kinematics During a Large Animal Acceleration Model of Traumatic Brain Injury. Front Neurol. 2021;12(852):658461. Epub 2021/06/29. doi: 10.3389/fneur.2021.658461. PubMed PMID: 34177763; PMCID: PMC8219951.

Smith DH, Dolle JP, Ameen-Ali KE, Bretzin A, Cortes E, Crary JF, Dams-O'Connor K, Diaz-Arrastia R, Edlow BL, Folkerth R, Hazrati LN, Hinds SR, Iacono D, Johnson VE, Keene CD, Kofler J, Kovacs GG, Lee EB, Manley G, Meaney D, Montine T, Okonkwo DO, Perl DP, Trojanowski JQ, Wiebe DJ, Yaffe K, McCabe T, Stewart W. COllaborative Neuropathology NEtwork Characterizing ouTcomes of TBI (CONNECT-TBI). Acta Neuropathol Commun. 2021;9(1):32. Epub 2021/03/03. doi: 10.1186/s40478-021-01122-9. PubMed PMID: 33648593; PMCID: PMC7919306.

ElSaadani M, Ahmed SM, Jacovides C, Lopez A, Johnson VE, Kaplan LJ, Smith DH, Pascual JL. Post-traumatic brain injury antithrombin III recovers Morris water maze cognitive performance, improving cued and spatial learning. J Trauma Acute Care Surg. 2021;91(1):108-13. Epub 2021/02/20. doi: 10.1097/TA.0000000000003112. PubMed PMID: 33605694; PMCID: PMC8528176.

Katiyar KS, Burrell JC, Laimo FA, Browne KD, Bianchi JR, Walters A, Ayares DL, Smith DH, Ali ZS, Ledebur HC, Cullen DK. Biomanufacturing of Axon-Based Tissue Engineered Nerve Grafts Using Porcine GalSafe Neurons. Tissue Eng Part A. 2021;27(19-20):1305-20. Epub 2021/01/31. doi: 10.1089/ten.TEA.2020.0303. PubMed PMID: 33514288; PMCID: PMC8610031.

Sullivan PZ, AlBayar A, Burrell JC, Browne KD, Arena J, Johnson V, Smith DH, Cullen DK, Ozturk AK. Implantation of Engineered Axon Tracts to Bridge Spinal Cord Injury Beyond the Glial Scar in Rats. Tissue Eng Part A. 2021;27(19-20):1264-74. Epub 2021/01/13. doi: 10.1089/ten.TEA.2020.0233. PubMed PMID: 33430694; PMCID: PMC8851225.

2020 PUBLICATIONS

Ezra Sadik M, Ozturk AK, Albayar A, Branche M, Zadnik Sullivan P, Schlosser, LO, Browne KD, Jaye AH, Smith DH. A Strategy Toward Bridging a Complete Spinal Cord Lesion Using Stretch-Grown Axons. Tissue Eng Part A. 2020 Jan 14. doi: 10.1089/ten.TEA.2019.0230. PMID 31852361 Impact factor = 4.

Arena, JD, Smith DH*, Lee EB, Gibbons GS, Irwin DJ, Robinson JL, Lee VMY, Trojanowski JQ, Stewart W, Johnson VE. Tau immunophenotypes in chronic traumatic encephalopathy recapitulate those of ageing and Alzheimer's disease. Brain 2020 May 1;143(5):1572-1587. doi: 10.1093/brain/awaa071. PMID 32390044 Impact factor = 11. 

Siman R, Cui H, Wewerka SS, Hamel L, Smith DH*, Zwank MD. Serum SNTF, a Surrogate Marker of Axonal Injury, Is Prognostic for Lasting Brain Dysfunction in Mild TBI Treated in the Emergency Department. Frontiers in Neurology. 2020 Apr 8;11:249. doi: 10.3389/fneur.2020.00249. eCollection 2020. PMID 32322237 Impact factor = 4.

Katiyar KS, Struzyna LA, Morand JP, Burrell JC, Clements B, Laimo FA, Browne KD Kohn J, Ali Z, Ledebur HC, Smith DH, Cullen DK. Tissue Engineered Axon Tracts Serve as Living Scaffolds to Accelerate Axonal Regeneration and Functional Recovery Following Peripheral Nerve Injury in Rats. Frontiers in Bioengineering and Biotechnology. 2020 May 25;8:492. doi: 10.3389/fbioe.2020.00492. eCollection 2020. PMID 32523945 Impact factor = 4.

Xu ZX, Albayar A, Dolle JP, Hansel G, Bianchini J, Sullivan PZ, Cullen DK, Smith DH, Ozturk AK. Dorsal root ganglion axons facilitate and guide cortical neural outgrowth: In vitro modeling of spinal cord injury axonal regeneration. Restorative Neurology and Neuroscience. 2020; 38(1):1-9. PMID 31594262  Impact factor = 2.

2020 REVIEWS AND COMMENTARIES

Smith DH, Stewart, W. ‘Concussion’ is not a true diagnosis. Nature Reviews Neurology. 2020 July 9. doi.org/10.1038/s41582-020-0382-y. PMID 32647140 Impact factor = 21.

Smith DH, Stewart W. Genetic interplay with soccer ball heading. Nature Reviews Neurology. 2020 Mar 9; pii: 10.1038/s41582-020-0334-6. doi: 10.1038/s41582-020-0334-6. PMID 32152459 Impact factor = 21.

Jgamadze D, Johnson VE, Wolf JA. Cullen DK, Song, H, Ming G, Smith DH, Chen HI. Modeling traumatic brain injury with human brain organoids. Current Opinion in Biomedical engineering. 2020 May 24 doi.org/10.1016/j.cobme.2020.05.004. Impact factor = 3.

2019 ORIGINAL RESEARCH

Verma R, Swanson RL, Parker D, Ould Ismail AA, Shinohara RT, Alappatt JA, Doshi J, Davatzikos C, Gallaway M, Duda D, Chen HI, Kim JJ, Gur RC, Wolf RL, Grady MS, Hampton S, Diaz-Arrastia R, Smith DH. Neuroimaging Findings in US Government Personnel With Possible Exposure to Directional Phenomena in Havana, Cuba. JAMA. 2019 Jul 23;322(4):336-347. doi: 10.1001/jama.2019.9269. PMID 31334794 Impact factor = 51.

Lee EB, Kinch K, Johnson VE, Trojanowski JQ, Smith DH*, Stewart W. Chronic traumatic encephalopathy is a common co-morbidity, but less frequent primary dementia in former soccer and rugby players. Acta Neuropathol. 2019 Jun 1. doi: 10.1007/s00401-019-02030-y. [Epub ahead of print]. PMID:31152201. Impact factor = 18. 

Gan ZS, Stein SC, Swanson R, Guan S, Garcia L, Mehta D, Smith DH. Blood Biomarkers for Traumatic Brain Injury: A Quantitative Assessment of Diagnostic and Prognostic Accuracy. Front Neurol. 2019 Apr 26;10:446. doi: 10.3389/fneur.2019.00446. eCollection 2019. PMID:31105646 | PMCID:PMC6498532. Impact factor = 4. 

Su YS, Schuster JM, Smith DH*, Stein SC. Cost-Effectiveness of Biomarker Screening for Traumatic Brain Injury. J Neurotrauma. 2019 Jul 1;36(13):2083-2091. doi: 10.1089/neu.2018.6020. Epub 2019 Mar 26. PMID:30547708. Impact factor = 4. 

Chen HI, Jgamadze D, Lim J, Mensah-Brown K, Wolf JA, Mills JA, Smith DH. Functional Cortical Axon Tracts Generated from Human Stem Cell-Derived Neurons. Tissue Eng Part A. 2019 May;25(9-10):736-745. doi: 10.1089/ten.TEA.2018.0270. Epub 2019 Mar 29. PMID:30648482 | PMCID:PMC6535960. Impact factor = 4.

Carteri RB, Kopczynski A, Rodolphi MS, Strogulski NR, Sartor M, Feldmann M, De Bastiani MA, Duval Wannmacher CM, de Franceschi ID, Hansel G, Smith DH*, Portela LV. Testosterone Administration after Traumatic Brain Injury Reduces Mitochondrial Dysfunction and Neurodegeneration. J Neurotrauma. 2019 Jul 15;36(14):2246-2259. doi: 10.1089/neu.2018.6266. Epub 2019 Apr 9. PMID:30794079. Impact factor = 4. 

Suto Y, Nagata K, Ahmed SM, Jacovides CL, Browne KD, Cognetti J, Johnson VE, Leone R, Kaplan LJ, Smith DH*, Pascual JL. Cerebral Edema and Neurological Recovery after Traumatic 

Brain Injury Are Worsened if Accompanied by a Concomitant Long Bone Fracture. J Neurotrauma. 2019 Feb 15;36(4):609-618. doi: 10.1089/neu.2018.5812. Epub 2018 Sep 7. PMID:30084745. Impact factor = 4. 

Jacovides CL, Ahmed S, Suto Y, Paris AJ, Leone R, McCarry J, Christofidou-Solomidou M, Kaplan LJ, Smith DH, Holena DN, Schwab CW, Pascual JL. An Inflammatory Pulmonary Insult Post-TBI Worsens Subsequent Spatial Learning and Neurological Outcomes. J Trauma Acute Care Surg. 2019 Sep;87(3):552-558. doi: 10.1097/TA.0000000000002403.PMID 31205212 Impact factor = 3.

2019 REVIEWS AND COMMENTARIES

Smith DH, Johnson VE, Trojanowski JQ, Stewart W. Chronic traumatic encephalopathy - confusion and controversies. Nat Rev Neurol. 2019 Mar;15(3):179-183. doi: 10.1038/s41582-018-0114-8. Review. PMID:30664683 | PMCID:PMC6532781. Impact factor = 21.

Verma, R, Swanson, RL, Smith, DH. Neuroimaging of US Government Personnel Exposed to Directional Phenomena-Reply. JAMA. 2019 Dec; 322(22): 2249-50. doi: 10.1001/jama.2019.16573. PMID 31821428 Impact factor = 51.

Stewart W, Allinson K, Al-Sarraj S, Bachmeier C, Barlow K, Belli A, Burns MP, Carson A, Crawford F, Dams-O'Connor K, Diaz-Arrastia R, Dixon CE, Edlow BL, Ferguson S, Fischl B, Folkerth RD, Gentleman S, Giza CC, Smith DH. Primum non nocere: a call for balance when reporting on CTE. Lancet Neurol. 2019 Mar;18(3):231-233. doi: 10.1016/S1474-4422(19)30020-1. Epub 2019 Feb 12. PMID 30784550 Impact factor = 30.

Albayar AA, Roche A, Swiatkowski P, Antar S, Ouda N, Emara E, Smith DH, Ozturk AK, Awad BI. Biomarkers in Spinal Cord Injury: Prognostic Insights and Future Potentials. Front Neurol. 2019 Jan 29;10:27. doi: 10.3389/fneur.2019.00027. eCollection 2019. Review. PMID:30761068 PMCID:PMC6361789. Impact factor = 4.

M Risling, DH Smith, TD Stein, EP Thelin, ER Zanier, M Ankarcrona. Modelling human pathology of traumatic brain injury in animal models. Journal of Internal Medicine 285 (6), 594-60 2019 JunPMID: 30963638. Impact factor = 7.

Knoll RM, Reinshagen KL, Barber SR, Ghanad I, Swanson R, Smith DH, Abdullah KG, Jung DH, Remenschneider AK, Kozin ED. High Resolution Computed Tomography Atlas of the Porcine Temporal Bone and Skull Base: Anatomical Correlates for Traumatic Brain Injury Research. J Neurotrauma. 2019 Apr 1;36(7):1029-1039. doi: 10.1089/neu.2018.5808. Epub 2018 Oct 5. PMID:29969939. Impact factor = 4.

2018 ORIGINAL RESEARCH

Swanson RL 2nd, Hampton S, Green-McKenzie J, Diaz-Arrastia R, Grady MS, Verma R, Biester R, Duda D, Wolf RL, Smith DH. Neurological Manifestations Among US Government Personnel Reporting Directional Audible and Sensory Phenomena in Havana, Cuba. JAMA. 2018 Mar 20;319(11):1125-1133. doi: 10.1001/jama.2018.1742.PMID:29450484 | PMCID:PMC5885885. Impact factor = 51.

Johnson VE, Weber MT, Xiao R, Cullen DK, Meaney DF, Stewart W, Smith DH. Mechanical disruption of the blood-brain barrier following experimental concussion. Acta Neuropathol. 2018 May;135(5):711-726. doi: 10.1007/s00401-018-1824-0. Epub 2018 Feb 19. PMID:29460006 | PMCID:PMC6532777. Impact factor = 18.

Dolle JP, Jaye A, Anderson SA, Ahmadzadeh H, Shenoy VB, Smith DH. Newfound sex differences in axonal structure underlie differential outcomes from in vitro traumatic axonal injury. Exp Neurol. 2018 Feb;300:121-134. doi: 10.1016/j.expneurol.2017.11.001. Epub 2017 Nov 22. PMID:29104114 | PMCID:PMC6495524. Impact factor = 5.

Dolle JP, Rodgers JM, Browne KD, Troxler T, Gai F, Smith DH. Newfound effect of N-acetylaspartate in preventing and reversing aggregation of amyloid-beta in vitro. Neurobiol Dis. 2018 Sep;117:161-169. doi: 10.1016/j.nbd.2018.05.023. Epub 2018 May 31. PMID:29859874 | PMCID:PMC6553457. Impact factor = 5.

Zanier ER, Bertani I, Sammali E, Pischiutta F, Chiaravalloti MA, Vegliante G, Masone A, Corbelli A, Smith DH, Menon DK, Stocchetti N, Fiordaliso F, De Simoni MG, Stewart W, Chiesa R. Induction of a transmissible tau pathology by traumatic brain injury. Brain. 2018 Sep 1;141(9):2685-2699. doi: 10.1093/brain/awy193.PMID:30084913 | PMCID:PMC6113646. Impact factor = 11.

Ulyanova AV, Koch PF, Cottone C, Grovola MR, Adam CD, Browne KD, Weber MT, Russo RJ, Gagnon KG, Smith DH, Isaac Chen H, Johnson VE, Kacy Cullen D, Wolf JA. Electrophysiological Signature Reveals Laminar Structure of the Porcine Hippocampus. eNeuro. 2018 Sep 18;5(5). pii: ENEURO.0102-18.2018. doi: 10.1523/ENEURO.0102-18.2018. eCollection 2018 Sep-Oct. PMID:30229132 | PMCID:PMC6142048. Impact factor = 4.

Kovacs GG, Xie SX, Robinson JL, Lee EB, Smith DH, Schuck T, Lee VM, Trojanowski JQ. Sequential stages and distribution patterns of aging-related tau astrogliopathy (ARTAG) in the human brain. Acta Neuropathol Commun. 2018 Jun 11;6(1):50. doi: 10.1186/s40478-018-0552-y. PMID:29891013 | PMCID:PMC5996526. Impact factor = 6.

Suto Y, Nagata K, Ahmed SM, Jacovides C, Browne KD, Cognetti J, Weber MT, Johnson VE, Leone R, Kaplan LJ, Smith DH, Pascual JL. A concomitant bone fracture delays cognitive recovery from traumatic brain injury. J Trauma Acute Care Surg. 2018 Aug;85(2):275-284. doi: 10.1097/TA.0000000000001957. PMID:29787539. Impact factor = 3.

Nagata K, Suto Y, Cognetti J, Browne KD, Kumasaka K, Johnson VE, Kaplan L, Marks J, Smith DH, Pascual JL.Early low-anticoagulant desulfated heparin after traumatic brain injury: Reduced brain edema and leukocyte mobilization is associated with improved watermaze learning ability weeks after injury. J Trauma Acute Care Surg. 2018 May;84(5):727-735. doi: 10.1097/TA.0000000000001819. PMID:29373460. Impact factor = 3.

2018 REVIEWS AND COMMENTARIES

Smith DH, Stewart W. Traumatic brain injury: a platform for studies in Ab processing: Commentary on: "Rapid Aboligomer and protofibril accumulation in traumatic brain injury". Brain Pathol. 2018 Jul;28(4):463-465. doi: 10.1111/bpa.12534. PMID:30133864 | PMCID:PMC6544357. Impact factor = 7.

Hampton S, Swanson RL 2nd, Smith DH. Neurological Symptoms in US Government Personnel in Cuba-Reply.JAMA. 2018 Aug 14;320(6):604-605. doi: 10.1001/jama.2018.8737.PMID:30120475. Impact factor = 51.

DeWitt DS, Hawkins BE, Dixon CE, Kochanek PM, Armstead W, Bass CR, Helen M Bramlett, Buki A, Dietrich WD, Ferguson AR, Hall ED, Hayes RL, Hinds SR, LaPlaca MC, Joseph B Long, David F Meaney, Stefania Mondello, Linda J Noble-Haeusslein, Poloyac SM, Prough DS, Robertson CS, Saatman KE, Shultz SR, Shear DA, Smith DH, Valadka AB, VandeVord P, Zhang L. Pre-Clinical Testing of Therapies for Traumatic Brain Injury. J Neurotrauma. 2018 Dec 1;35(23):2737-2754. doi: 10.1089/neu.2018.5778. Epub 2018 Aug 30. PMID:29756522. Impact factor = 5.

2017 ORIGINAL RESEARCH

Chen HI, Wolf JA, Smith DH. Multichannel activity propagation across an engineered axon network. J Neural Eng. 2017 Apr;14(2):026016. doi: 10.1088/1741-2552/aa5ccd. Epub 2017 Jan 31. PMID: 28140365;  PMCID: PMC5417339. Impact factor = 5.

Wolf JA, Johnson BN, Johnson VE, Putt ME, Browne KD, Mietus CJ, Brown DP, Wofford KL, Smith DH, Grady MS, Cohen AS, Cullen DK. Concussion Induces Hippocampal Circuitry Disruption in Swine. J Neurotrauma. 2017 Jul 15;34(14):2303-2314. doi: 10.1089/neu.2016.4848. Epub 2017 May 4. PMID: 28298170. Impact factor = 5.

Stefani MA, Modkovski R, Hansel G, Zimmer ER, Kopczynski A, Muller AP, Strogulski NR, Rodolphi MS, Carteri RK, Schmidt AP, Oses JP, Smith DH, Portela LV. Elevated glutamate and lactate predict brain death after severe head trauma. Ann Clin Transl Neurol. 2017 May 4;4(6):392-402. doi: 10.1002/acn3.416. eCollection 2017 Jun. PMID: 28589166;  PMCID: PMC5454398. Impact factor = 4.

Nagata K, Browne KD, Suto Y, Kumasaka K, Cognetti J, Johnson VE, Marks J, Smith DH, Pascual JL. Early Heparin Administration After TBI: Prolonged Cognitive Recovery Associated With Reduced Cerebral Edema and Neutrophil Sequestration. J Trauma Acute Care Surg. 2017 May 22. doi: 10.1097/TA.0000000000001590. [Epub ahead of print] PMID: 28538627. Impact factor = 3.

Kovacs GG, Xie SX, Lee EB, Robinson JL, Caswell C, Irwin DJ, Toledo JB, Johnson VE, Smith DH, Alafuzoff I, Attems J, Bencze J, Bieniek KF, Bigio EH, Bodi I, Budka H, Dickson DW, Dugger BN, Duyckaerts C, Ferrer I, Forrest SL, Gelpi E, Gentleman SM, Giaccone G, Grinberg LT, Halliday GM, Hatanpaa KJ, Hof PR, Hofer M, Hortobagyi T, Ironside JW, King A, Kofler J, Kovari E, Kril JJ, Love S, Mackenzie IR, Mao Q, Matej R, McLean C, Munoz DG, Murray ME, Neltner J, Nelson, PT, Ritchie D, Rodriguez RD, Rohan Z, Rozemuller A., Sakai K, Schultz C, Seilhean D, Smith V, Tacik P, Takahashi H, Takao, M, Rudolf Thal D, Weis S, Wharton SB, White CL 3^rd, Woulfe JM, Yamada M, Trojanowski JQ. Multisite Assessment of Aging-Related Tau Astrogliopathy (ARTAG). J Neuropathol Exp Neurol. 2017 Jul 1;76(7):605-619. 

doi: 10.1093/jnen/nlx041. PMID 28591867 Impact factor = 3.

2017 REVIEWS AND COMMENTARIES

Cernak I, Stein DG, Elder GA, Ahlers S, Curley K, DePalma RG, Duda J, Ikonomovic M, Iverson GL, Kobeissy F, Koliatsos VE, Leggieri MJ Jr, Pacifico AM, Smith DH, Swanson R, Thompson FJ, Tortella FC. Preclinical modelling of militarily relevant traumatic brain injuries: Challenges and recommendations for future directions. Brain Inj. 2017;31(9):1168-1176. doi: 10.1080/02699052.2016.1274779. Review. PMID:28981339. Impact factor = 2.

Johnson VE, Stewart W, Arena JD, Smith DH. Traumatic Brain Injury as a Trigger of Neurodegeneration. Adv Neurobiol. 2017; 15:383-400. doi: 10.1007/978-3-319-57193-5_15. PMID: 28674990. 

2016 ORIGINAL RESEARCH

Johnson VE, Stewart W, Weber MT, Cullen DK, Siman R, Smith DH. SNTF immunostaining reveals previously undetected axonal pathology in traumatic brain injury. Acta Neuropathol. 2016 Jan;131(1):115-35. doi: 10.1007/s00401-015-1506-0. PMID: 26589592;  PMCID: PMC4780426. Impact factor = 18.

Purohit PK, Smith DH. A model for stretch of neurons. J Biomech. 2016 Dec 8;49(16):3934-3942. doi: 10.1016/j.jbiomech.2016.11.045. PMID: 27890538. Impact factor = 3 

Ali ZS, Johnson VE, Stewart W, Zager EL, Xiao R, Heuer GG, Weber MT, Mallela AN, Smith DH. Neuropathological Characteristics of Brachial Plexus Avulsion Injury With and Without Concomitant Spinal Cord Injury. J Neuropathol Exp Neurol. 2016 Jan; 75(1):69-85. PMID: 26671984. Impact factor = 3.

Cullen DK, Harris JP, Browne KD, Wolf JA, Duda JE, Meaney DF, Margulies SS, Smith DH. A Porcine Model of Traumatic Brain Injury via Head Rotational Acceleration. Methods Mol Biol. 2016;1462:289-324. doi:10.1007/978-1-4939-3816-2_17. PMID: 27604725. Impact factor = 11.

Li S, Eisenstadt R, Kumasaka K, Johnson VE, Marks J, Nagata K, Browne KD, Smith DH, Pascual JL. Does enoxaparin interfere with HMGB1 signaling after TBI? A potential mechanism for reduced cerebral edema and neurologic recovery. J Trauma Acute Care Surg. 2016 Mar;80(3):381-7; discussion 387-9. doi:10.1097/TA.0000000000000935. PMID: 26670109. Impact factor = 3.

Nagata K, Kumasaka K, Browne KD, Li S, St-Pierre J, Cognetti J, Marks J, Johnson VE, Smith DH, Pascual JL. Unfractionated heparin after TBI reduces in vivo cerebrovascular inflammation, brain edema and accelerates cognitive recovery. J Trauma Acute Care Surg. 2016 Dec;81(6):1088-1094. PMID: 27533909. Impact factor = 3.

2016 REVIEWS AND COMMENTARIES

Stewart W, Smith DH. Time to be blunt about blast traumatic brain injury. Lancet Neurol. 2016 Aug;15(9):896-8. doi: 10.1016/S1474-4422(16)30058-8. PMID: 27291519.  Impact factor = 30.

Smith DH, Stewart W. Tackling concussion, beyond Hollywood. Lancet Neurol. 2016 Jun;15(7):662-3. doi: 10.1016/S1474-4422(16)30037-0. PMID: 27302233. Impact factor = 30.

Chen HI, Jgamadze D, Serruya MD, Cullen DK, Wolf JA, Smith DH. Neural Substrate Expansion for the Restoration of Brain Function. Front Syst Neurosci. 2016 Jan 25;10:1. doi: 10.3389/fnsys.2016.00001. Review. PMID: 26834579;  PMCID: PMC4724716. Impact factor = 4.

Smith DH. Neuromechanics and Pathophysiology of Diffuse Axonal Injury in Concussion. Bridge. 2016 Spring;46(1):79-84. Epub 2016 Apr 12. PMID 28867874 Impact factor = 3.

Hay J, Johnson VE, Smith DH*, Stewart W. Chronic Traumatic Encephalopathy: The Neuropathological Legacy of Traumatic Brain Injury. Annu Rev Pathol. 2016 May 23;11:21-45. doi: 10.1146/annurev-pathol-012615-044116. PMID: 26772317. Impact factor = 12. 

2015 ORIGINAL RESEARCH

Smith DH, Hicks RR, Johnson VE, Bergstrom DA, Cummings DM, Noble LJ, Hovda D, Whalen M, Ahlers ST, LaPlaca M, Tortella FC, Duhaime AC, Dixon CE. Pre-Clinical Traumatic Brain Injury Common Data Elements: Toward a Common Language Across Laboratories. J Neurotrauma. 2015 Nov 15;32(22):1725-35. doi:10.1089/neu.2014.3861. PMID: 26058402; PMCID: PMC4651035. Impact factor = 5.

Ahmadzadeh H, Smith DH*, Shenoy VB. Mechanical Effects of Dynamic Binding between Tau Proteins on Microtubules during Axonal Injury. Biophys J. 2015 Dec 1;109(11):2328-37. doi: 10.1016/j.bpj.2015.09.010. PMID: 26636944; PMCID: PMC4675823. Impact factor = 4. 

Siman R, Shahim P, Tegner Y, Blennow K, Zetterberg H, Smith DH. Serum SNTF Increases in Concussed Professional Ice Hockey Players and Relates to the Severity of Postconcussion Symptoms. J Neurotrauma. 2015 Sep 1;32(17):1294-300. doi: 10.1089/neu.2014.3698. PMID: 25419578; PMCID: PMC4543483. Impact factor = 5.

Hay JR, Johnson VE, Young AM, Smith DH*, Stewart W. Blood-Brain Barrier Disruption Is an Early Event That May Persist for Many Years After Traumatic Brain Injury in Humans. J Neuropathol Exp Neurol. 2015 Dec;74(12):1147-57. doi: 10.1097/NEN.0000000000000261.  PMID: 26574669. Impact factor = 3. 

Struzyna LA, Wolf JA, Mietus CJ, Adewole DO, Chen HI, Smith DH, Cullen DK. Rebuilding Brain Circuitry with Living Micro-Tissue Engineered Neural Networks. Tissue Eng Part A. 2015 Nov;21(21-22):2744-56. doi: 10.1089/ten.TEA.2014.0557. PMID: 26414439; PMCID: PMC4652241. Impact factor = 4.

Li S, Marks JA, Eisenstadt R, Kumasaka K, Samadi D, Johnson VE, Holena DN, Allen SR, Browne KD, Smith DH, Pascual JL. Enoxaparin ameliorates post-traumatic brain injury edema and neurologic recovery, reducing cerebral leukocyte endothelial interactions and vessel permeability in vivo. J Trauma Acute Care Surg. 2015 Jul;79(1):78-84. doi: 10.1097/TA.0000000000000697. PMID: 26091318. Impact factor = 3.

2015 REVIEWS AND COMMENTARIES

Meaney DF, Smith DH. Cellular biomechanics of central nervous system injury. Handb Clin Neurol. 2015;127:105-14. doi: 10.1016/B978-0-444-52892-6.00007-6. PMID: 25702212; PMCID: PMC4946950. Impact factor = 2.

Johnson VE, Meaney DF, Cullen DK, Smith DH. Animal models of traumatic brain injury. Handb Clin Neurol.2015;127:115-28. doi:10.1016/B978-0-444-52892-6.00008-8. PMID: 25702213; PMCID: PMC4946951. Impact factor = 2.