Naji Alamuddin, MD

Naji Alamuddin, MD
Naji Alamuddin, MD

Naji Alamuddin, MD, MTR, is an assistant professor of medicine at the Perelman School of Medicine at the University of Pennsylvania. He received his medical degree from the Royal College of Surgeons in Ireland, and Masters in Translational Research from the University of Pennsylvania. He completed an internal medicine residency at Pennsylvania Hospital, and fellowship in diabetes, endocrinology, and metabolism at the Hospital of the University of Pennsylvania. He is board certified in internal medicine, endocrinology, diabetes, and metabolism, and is a diplomate of the American Board of Obesity Medicine.

Dr. Alamuddin’s research focuses on the treatment of obesity, involving behavioral, pharmacological, and surgical approaches. He is primarily interested in understanding metabolic changes associated with weight loss and bariatric surgery.

Dr. Alamuddin can be contacted at: University of Pennsylvania Perelman School of Medicine, 3535 Market St., Suite 3021, Philadelphia, PA 19104. His e-mail address is

Recent publications

Tronieri, JS, Wadden TA, Berkowitz RI, Chao AO, Pearl RL, Alamuddin N, Leonard SM, Carvajal R, Bakizada ZM, Pinkasavage E, Gruber KA, Walsh OA, Alfaris N. A Randomized Controlled Trial of Lorcaserin and Lifestyle Counseling for Maintaining Weight Loss Achieved with a Low-Calorie Diet. Obesity (Silver Spring). 2017. In press

Tronieri JS, Alfaris N, Chao AM, Pearl RL, Alamuddin N, Bakizada ZM, Berkowitz RI, Wadden TA. Lorcaserin plus lifestyle modification for weight loss maintenance: Rationale and design for a randomized controlled trial. Contemp Clin Trials. 59:105-112. 2017

Pearl RL, Wadden TA, Hopkins CM, Shaw JA, Hayes MR, Bakizada ZM, Alfaris N, Chao AM, Pinkasavage E, Berkowitz RI, Alamuddin N. Association Between Weight Bias Internalization and Metabolic Syndrome Among Treatment-Seeking Individuals with Obesity. Obesity (Silver Spring). 25:317-322, 2017

Alamuddin N, Vetter ML, Ahima RS, Hesson L, Ritter S, Minnick A, Faulconbridge LF, Allison KC, Sarwer DB, Chittams J, Williams NN, Hayes MR, Loughead JW, Gur R, Wadden TA. Changes in Fasting and Prandial Gut and Adiposity Hormones Following Vertical Sleeve Gastrectomy or Roux-en-Y-Gastric Bypass: An 18-month controlled study. Obesity Surgery. 2016

Chao AM, Shaw JA, Pearl RL, Alamuddin N, Hopkins CM, Bakizada ZM, Berkowitz RI, Wadden TA. Prevalence and psychosocial correlates of food addiction in persons with obesity seeking weight reduction. Compr Psychiatry. 73:97-104, 2016

Alamuddin N, Bakizada Z, Wadden TA. Management of obesity. Journal of Clinical Oncology. 34:4295-4305, 2016

Chao AM, Wadden TA, Faulconbridge LF, Sarwer DB, Webb VL, Shaw J, Thomas JG, Hopkins CM, Bakizada ZM, Alamuddin N, Williams NN. Binge eating disorder and the outcome of bariatric surgery in a prospective, observational study: Two year results. Obesity (Silver Spring). 2016

Alamuddin N, Wadden TA. Behavioral treatment of the patient with obesity. Endocrinol Metab Clin North Am. 45:565-80, 2016

Skarke C, Alamuddin N, Lawson JA, Ferguson JF, Reilly MP, FitzGerald GA. Bioactive products formed in humans from fish oils.  J Lipid Res 56:1808-20, 2015

Hirankarn S, Barrett JS, Alamuddin N, FitzGerald GA, Skarke C.  CG100649, A Novel Cyclooxygenase-2 Inhibitor, Exhibits a Drug Disposition Profile in Healthy Volunteers Compatible With High Affinity to Carbonic Anhydrase-I/II: Preliminary Dose–Exposure Relationships to Define Clinical Development Strategies. Clin Pharmacol Drug Dev 2:379-86, 2013

Song WL, Stubbe J, Ricciotti E, Alamuddin N, Ibrahim S, Crichton I, Prempeh M, Lawson JA, Wilensky RL, Rasmussen LM, Puré E, Fitzgerald GA. Niacin and biosynthesis of PGD2 by platelet COX-1 in mice and humans. J Clin Invest 122:1459-68, 2012

Skarke C, Alamuddin N, Lawson JA, Cen L, Propert KJ, Fitzgerald GA. Comparative Impact on Prostanoid Biosynthesis of Celecoxib and the Novel Nonsteroidal Anti-Inflammatory Drug CG100649. Clin Pharmacol Ther 91:986-93, 2012



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