Shape-shifting Disease Proteins May Explain Variable Appearance of Neurodegenerative Diseases, Penn Study Finds
Targeting Distinct Alpha-synuclein Strains a Potential Treatment Approach
Neurodegenerative diseases are not all alike. Two individuals suffering from the same disease may experience very different age of onset, symptoms, severity, and constellation of impairments, as well as different rates of disease progression. Researchers in the Perelman School of Medicine at the University of Pennsylvania have shown one disease protein can morph into different strains and promote misfolding of other disease proteins commonly found in Alzheimer's, Parkinson's and other related neurodegenerative diseases.
IOA in the News
Sylvan M. Cohen 2014 Annual Retreat: "The Gender Gap in Aging & The 21st Century Longevity Revolution"
co-sponsored by Penn Center for the Study of Sex and Gender in Behavioral Health and Medicine
featuring Susan M. Resnick, PhD, C. Neill Epperson, MD, and Tracy L. Bale, PhD
Wednesday, May 14, 2014 | Smilow Center | 11:30am - 5:00pm
To register for the event and/or submit a poster, please Email: Aging@mail.med.upenn.edu OR Call: 215-898-7801 with the following information, by Friday, May 2:
- Your name, poster title, category (basic science, clinical research, or education and community), your affiliation, names of authors (contributors) and presenter
Join the nearly 300 Institute on Aging Fellows and Associate Fellows and experience robust collaborative opportunities in aging at Penn, for funding opportunity alerts, pilot research grant opportunities, and updates on IOA activities.Get Involved
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