Department of Psychiatry
Penn Behavioral Health

Depression Research Unit (DRU)

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Faculty and Staff


Jay D. Amsterdam, MD
Director, Depression Research Unit (DRU)
Professor of Psychiatry

Dr. Amsterdam is Professor of Psychiatry at the Perelman School of Medicine at the University of Pennsylvania and Director of the Depression Research Unit (DRU). Dr. Amsterdam is a graduate of Syracuse University with a degree in American Studies. He received his MD degree from Jefferson Medical College and his postgraduate training in psychiatry at Thomas Jefferson University Hospital and Maudsley Hospital of the University of London. Dr. Amsterdam undertook a post-doctoral fellowship, training in affective disorders, at the Perelman School of Medicine at the University of Pennsylvania, and a second NIMH-sponsored post-doctoral fellowship in neuropsychopharmacology at the University of Pennsylvania. He was appointed Assistant Professor of Psychiatry at the Perelman School of Medicine at the University of Pennsylvania in 1980, Associate Professor in 1986, and full Professor in 1992. He previously held an appointment as Adjunct Professor at the Wistar Institute in Philadelphia.

Dr. Amsterdam has been Director of the DRU at Penn since 1980. His research interests in mood disorders have included work in the areas of psychopharmacology, new antidepressant drug development, psychoneuroendocrinology, psychoimmunovirology, molecular brain imaging, and studies of bipolar disorder and resistant depression. He is principal author or co-author of over 225 original articles, reviews and chapters, and has edited and co-authored 5 textbooks on the psychopharmacology of mood disorders. Dr. Amsterdam has received awards acknowledging his expertise as a clinical researcher and teacher including the Marie H. Eldredge Award of the American Psychiatric Association, the Curt P. Richter Prize of the International Society of Psychoneuroendocrinology, and is a distinguished Fellow of the American Psychiatric Association. Dr. Amsterdam serves as a reviewer for many scientific and research journals, and is on the editorial board of national and international journals. He has been the principal investigator on many research grants and is the administrator of the Jack Warsaw Fund for Research in Biological Psychiatry.

DerubeisRobert J. DeRubeis, PhD                                         

Professor of Psychology, SAS
Professor of Psychology in Psychiatry, SOM

Dr. DeRubeis is Professor of Psychology in the School of Arts and Sciences at the University of Pennsylvania, and Professor of Psychology in Psychiatry at the Perelman School of Medicine at the University of Pennsylvania. He received his undergraduate degree in Psychology from the University of Wisconsin, and earned his PhD in Clinical Psychology at the University of Minnesota. He is former Chair of the Department of Psychology at Penn, and former Associate Dean of Social Sciences in the School of Arts and Sciences at the University of Pennsylvania. Dr. DeRubeis is the principal investigator of the National Institute of Mental Health funded study entitled "Preventing the Recurrence of Depression Using Drugs and Cognitive Therapy". He is clinical supervisor of the cognitive therapy research and clinical program on the DRU. Dr. DeRubeis' research interests focus on the causes of depression, the effectiveness of various treatments, and the psychological and biological mechanisms of cognitive therapy.

Penn Psychology: Robert J. DeRubeis, Ph.D.

Jun Mao, M.D.Jun James Mao, MD, MSCE

Associate Professor of Family Medicine and Community Health

Dr. Mao is an Associate Professor and Director of Integrative Medicine in the Department of Family Medicine and Community Health at the Perelman School of Medicine at the University of Pennsylvania. He is a board certified family physician who is also trained in Chinese medicine and acupuncture. Dr. Mao combines Eastern and Western approaches to the study and treatment of mood and anxiety disorders. He is a co-investigator (along with his DRU colleagues) on research studies of complementary and alternative medicines that are being conducted on the DRU.



Ian Bennett, M.D., Ph.D.Ian Bennett, M.D., Ph.D.

Associate Professor, Department of Family Medicine and Community Health and the Center of Public Health Initiatives Perelman School of Medicine of the University of Pennsylvania

Dr. Bennett is a family physician providing full spectrum primary care including obstetric, pediatric and general adult health care. He also conducts health services research in the implementation of evidence based care models for perinatal depression. He is the primary investigator or co-investigator of multiple grants funded by the National Institutes of Health as well as foundations (WK Kellog Foundation and the Robert Wood Johnson Foundation) investigating perinatal depression care in low income race/ethnic minority populations in diverse geographic settings. He has particular expertise in the delivery of health services within Federally Qualified Health Centers and is the PI of a three year prospective study of the implementation of team based care for perinatal depression in four FQHCs in southcentral and southeast Pennsylvania. He is currently a fellow in the Implementation Research Institute funded by the NIMH at Washington University with a project focus on implementing collaborative care models for perinatal depression in FQHCs.



Irene Soeller, CRNP
Nurse Practitioner
Theresa Tiliakos
Clinical Research Coordinator




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