Focused on the diverse scientific challenges associated with the development of PET radiotracers for imaging proteinopathies

The “Center Without Walls for Imaging Proteinopathies with PET (CW₂IP₂)” consists of a multi-institutional collaboration of PET Centers that spans the continental US.  It also consists of the scientific integration of individuals with an international reputation in the fields of neurobiology, neuropathology, neurology, structural biology, medicinal chemistry, PET radiochemistry and CNS PET imaging studies towards the common goal of developing PET radiotracers for imaging aggregated alpha synuclein and 4R tau, and their role in neurodegenerative disorders such as Parkinson’s disease, Multiple System Atrophy and Frontotemporal Dementia.  The scientific resources that emerge from this multi-disciplinary and multi-institutional research effort will have an important impact on the scientific mission of the National Institute on Neurological Disorders and Stroke (NINDS) and the National Institute on Aging (NIA).

Center Structure: