Brodkin Lab Representative Publications

Xu B, Ho Y, Fasolino M, Medina J, O'Brien WT, Lamonica JM, Nugent E, Brodkin ES, Fuccillo MV, Bucan M, Zhou Z. "Allelic contribution of Nrxn1α to autism-relevant behavioral phenotypes in mice." PLoS Genet. 2023 Feb 27;19(2):e1010659. doi: 10.1371/journal.pgen.1010659. eCollection 2023 Feb. PMID: 36848371

Taylor SC, Gehringer BN, Dow HC, Langer A, Rawot E, Smernoff Z, Steeman S, Almasy L, Rader DJ, Bučan M, Brodkin ES. "Contrasting Views of Autism Spectrum Traits in Adults, Especially in Self-Reports vs. Informant-Reports for Women High in Autism Spectrum Traits. "J Autism Dev Disord. 2022 Dec 9:1-13. doi: 10.1007/s10803-022-05822-6. Online ahead of print. PMID: 36484966

Taylor SC, Smernoff ZL, Rajan M, Steeman S, Gehringer BN, Dow HC, Barzilay R, Rader DJ, Bucan M, Almasy L, Brodkin ES. “Investigating the relationships between resilience, autism-related quantitative traits, and mental health outcomes among adults during the COVID-19 pandemic. " J Psychiatr Res. 2022 Apr;148:250-257. doi: 10.1016/j.jpsychires.2022.01.046. Epub 2022 Jan 29. PMID: 35151216

Taylor SC, Steeman S, Gehringer BN, Dow HC, Langer A, Rawot E, Perez L, Goodman M, Smernoff Z, Grewal M, Eshraghi O, Pallathra AA, Oksas C, Mendez M, Gur RC, Rader DJ, Bucan M, Almasy L, Brodkin ES.; “Heritability of quantitative autism spectrum traits in adults: A family-based study. “ Autism Res.2021 Jul 10. doi: 10.1002/aur.2571. Online ahead of print. PMID: 34245229

Greene RK, Parish-Morris J, Sullivan M, Kinard JL, Mosner MG, Turner-Brown LM, Penn DL, Wiesen CA, Pallathra AA, Brodkin ES, Schultz RT, Dichter GS.:"Dynamic Eye Tracking as a Predictor and Outcome Measure of Social Skills Intervention in Adolescents and Adults with Autism Spectrum Disorder. " J Autism Dev Disord. 2021 Apr;51(4):1173-1187. doi: 10.1007/s10803-020-04594-1. PMID: 32656738

Ferri SL, Dow HC, Schoch H, Lee JY, Brodkin ES, Abel T. :"Age- and sex-specific fear conditioning deficits in mice lacking Pcdh10, an Autism Associated Gene. "  Neurobiol Learn Mem. 2021 Feb;178:107364. doi: 10.1016/j.nlm.2020.107364. Epub 2020 Dec 16. PMID: 33340671

Mailey C, Day-Watkins J, Pallathra AA, Eckerman DA, Brodkin ES, Connell JE. “Using Adaptive Computer-based Instruction to Teach Staff to Implement a Social Skills Intervention.” J Organ Behav Manage. 2021;41(1):2-15. doi: 10.1080/01608061.2020.1776807. Epub 2020 Jun 22. PMID: 34239214

Taylor SC, Ferri SL, Grewal M, Smernoff Z, Bucan M, Weiner JA, Abel T, Brodkin ES. :“The Role of Synaptic Cell Adhesion Molecules and Associated Scaffolding Proteins in Social Affiliative Behaviors.” Biol Psychiatry, 2020 Sep 15;88(6):442-451. doi: 10.1016/j.biopsych.2020.02.012. Epub 2020 Feb 22. PMID: 32305215

Matsuzaki J, Ku M, Dipiero M, Chiang T, Saby J, Blaskey L, Kuschner ES, Kim M, Berman JI, Bloy L, Chen YH, Dell J, Liu S, Brodkin ES, Embick D, Roberts TPL.:”Delayed Auditory Evoked Responses in Autism Spectrum Disorder across the Life Span.” Dev Neurosci., 2019;41(3-4):223-233. doi: 10.1159/000504960. Epub 2020 Jan 31. PMID: 32007990

Ferri SL, Pallathra AA, Kim H, Dow HC, Raje P, McMullen M, Bilker WB, Siegel SJ, Abel T, Brodkin ES: “Sociability development in mice with cell-specific deletion of the NMDA receptor NR1 subunit gene. “ Genes Brain Behav. 2020 Jan;19(1):e12624. doi: 10.1111/gbb.12624. Epub 2019 Dec 12. PMID: 31721416

Parish-Morris J, Pallathra AA, Ferguson E, Maddox BB, Pomykacz A, Perez LS, Bateman L, Pandey J, Schultz RT, Brodkin ES. “Adaptation to different communicative contexts: an eye tracking study of autistic adults. “ J Neurodev Disord., 2019 Apr 13;11(1):5. doi:10.1186/s11689-019-9265-1. PMID: 30981277

de Marchena A, Kim ES, Bagdasarov A, Parish-Morris J, Maddox BB, Brodkin ES, Schultz RT. "Atypicalities of Gesture Form and Function in Autistic Adults. " J Autism Dev Disord. 2019 Apr;49(4):1438-1454. doi: 10.1007/s10803-018-3829-x. PMID: 30523479

Pallathra AA, Cordero L, Wong K, Brodkin ES. “Psychosocial Interventions Targeting Social Functioning in Adults on the Autism Spectrum: a Literature Review. “, Curr Psychiatry Rep. 2019 Jan 31;21(1):5. doi: 10.1007/s11920-019-0989-0. PMID: 30706149 Free PMC article. Review.

Day-Watkins J, Pallathra AA, Connell JE, Brodkin ES.: “Behavior Skills Training with Voice-Over Video Modeling. “ J Organ Behav Manage. 2018;38(2-3):258-273. doi: 10.1080/01608061.2018.1454871. Epub 2018 May 3. PMID: 31571704 Free PMC article.

Pallathra AA, Calkins ME, Parish-Morris J, Maddox BB, Perez LS, Miller J, Gur RC, Mandell DS, Schultz RT, Brodkin ES.: “Defining behavioral components of social functioning in adults with autism spectrum disorder as targets for treatment.” Autism Res. 2018 Mar;11(3):488-502. doi: 10.1002/aur.1910. Epub 2018 Jan 17. PMID: 29341497 Free PMC article.

Ferri SL, Abel T, Brodkin ES.: “Sex Differences in Autism Spectrum Disorder: a Review. “ Curr Psychiatry Rep. 2018 Mar 5;20(2):9. doi: 10.1007/s11920-018-0874-2. PMID: 29504047 Free PMC article. Review.

Baker-Ericzén MJ, Brookman-Frazee L, Brodkin ES.: "Accelerating research on treatment and services for transition age youth and adults on the autism spectrum." Autism, 2018, Jan; 22(1):2-5. doi: 10.1177/1362361317738646. No abstract available. PMID:29369717  

Port RG, Gajewski C, Krizman E, Dow HC, Hirano S, Brodkin ES, Carlson GC, Robinson MB, Roberts TPL, Siegel SJ.: “Protocadherin 10 alters γ oscillations, amino acid levels, and their coupling; baclofen partially restores these oscillatory deficits.”  Neurobiology of Disease, 2017, Aug 24;108:324-338. doi: 10.1016/j.nbd.2017.08.013. [Epub ahead of print] PMID: 28844789

Maddox BB, Brodkin ES, Calkins ME, Shea K, Mullan K, Hostager J, Mandell DS, Miller JS.: “The Accuracy of the ADOS-2 in Identifying Autism among Adults with Complex Psychiatric Conditions.” The Journal of Autism and Developmental Disorders, 2017, Jun 6. doi: 10.1007/s10803-017-3188-z. [Epub ahead of print] PMID: 28589494

Port RG, Gaetz W, Bloy L, Wang DJ, Blaskey L, Kuschner ES, Levy SE, Brodkin ES, Roberts TPL.: “Exploring the relationship between cortical GABA concentrations, auditory gamma-band responses and development in ASD: Evidence for an altered maturational trajectory in ASD.”  Autism Research, 2017, Apr;10(4):593-607. doi: 10.1002/aur.1686. Epub 2016 Oct 1. PMID: 27696740

Schoch H, Kreibich AS, Ferri SL, White RS, Bohorquez D, Banerjee A, Port RG, Dow HC, Cordero L, Pallathra AA, Kim H, Li H, Bilker WB, Hirano S, Schultz RT, Borgmann-Winter K, Hahn CG, Feldmeyer D, Carlson GC, Abel T, Brodkin ES.: “Sociability Deficits and Altered Amygdala Circuits in Mice Lacking Pcdh10, an Autism Associated Gene.” Biological Psychiatry, 2017, Feb 1;81(3):193-202. doi: 10.1016/ j.biopsych.2016.06.008. Epub 2016 Jun 16. PMID: 27567313

Ferri SL, Kreibich AS, Torre M, Piccoli CT, Dow H, Pallathra AA, Li H, Bilker WB, Gur RC, Abel T, Brodkin ES.: “Activation of basolateral amygdala in juvenile C57BL/6J mice during social approach behavior.” Neuroscience, 2016, Oct 29;335:184-94. doi: 10.1016/ j.neuroscience.2016.08.006. Epub 2016 Aug 9. PMID: 27520082

Wood KH, Johnson BS, Welsh SA, Lee JY, Cui Y, Krizman E, Brodkin ES, Blendy JA, Robinson MB, Bartolomei MS, Zhou Z.: “Tagging methyl-CpG-binding domain proteins reveals different spatiotemporal expression and supports distinct functions.” Epigenomics, 2016, Apr;8(4):455-73. doi: 10.2217/epi-2015-0004. Epub 2016 Apr 12. PMID: 27066839

Briand LA, Hilario M, Dow HC, Brodkin ES, Blendy JA, Berton O.: “Mouse model of OPRM1 (A118G) polymorphism increases sociability and dominance and confers resilience to social defeat.” Journal of Neuroscience, 2015, Feb 25;35(8):3582-90. doi: 10.1523/JNEUROSCI.4685-14.2015. PMID: 25716856

Kumar M, Duda JT, Hwang WT, Kenworthy C, Ittyerah R, Pickup S, Brodkin ES, Gee JC, Abel T, Poptani H.: “High resolution magnetic resonance imaging for characterization of the neuroligin-3 knock-in mouse model associated with autism spectrum disorder.” PLoS One, 2014, Oct 9;9(10):e109872. doi: 10.1371/journal.pone.0109872. eCollection 2014. PMID: 25299583

Goffin D, Brodkin ES, Blendy JA, Siegel SJ, Zhou Z.: “Cellular origins of auditory event-related potential deficits in Rett syndrome.” Nature Neuroscience, 2014, Jun;17(6):804-6. doi: 10.1038/nn.3710. Epub 2014 Apr 28. PMID: 24777420

Liu J, Richmond TS, Raine A, Cheney R, Brodkin ES, Gur RC, Gur RE.: “The Healthy Brains and Behavior Study: objectives, design, recruitment, and population coverage.” International Journal of Methods in Psychiatric Research, 2013, Sep;22(3):204-16. doi: 10.1002/mpr.1394. PMID: 25931327

Fairless AH, Katz JM, Vijayvargiya N, Dow HC, Kreibich AS, Berrettini WH, Abel T, Brodkin ES.: “Development of home cage social behaviors in BALB/cJ vs. C57BL/6J mice.” Behavioural Brain Research, 2013, Jan 15;237:338-47. doi: 10.1016/j.bbr.2012.08.051. Epub 2012 Sep 5. PMID: 22982070

Wang IT, Allen M, Goffin D, Zhu X, Fairless AH, Brodkin ES, Siegel SJ, Marsh ED, Blendy JA, Zhou Z.: “Loss of CDKL5 disrupts kinome profile and event-related potentials leading to autistic-like phenotypes in mice.” Proceedings of the National Academy of Sciences of the United States of America, 2012, Dec 26;109(52):21516-21. doi: 10.1073/pnas.1216988110. Epub 2012 Dec 10. PMID: 23236174

Chevallier C, Kohls G, Troiani V, Brodkin ES, Schultz RT.: “The social motivation theory of autism.” Trends in Cognitive Sciences, 2012, Apr;16(4):231-9. doi: 10.1016/j.tics.2012.02.007. Epub 2012 Mar 17. Review. PMID: 22425667

Fairless AH, Dow HC, Kreibich AS, Torre M, Kuruvilla M, Gordon E, Morton EA, Tan J, Berrettini WH, Li H, Abel T, Brodkin ES.: “Sociability and brain development in BALB/cJ and C57BL/6J mice.”  Behavioural Brain Research, 2012, Mar 17;228(2):299-310. doi: 10.1016/j.bbr.2011.12.001. Epub 2011 Dec 9. PMID: 22178318

Fairless A.H., Shah R.Y., Guthrie A.J., Li H., Brodkin E.S.: “Deconstructing sociability, an autism-relevant phenotype, in mouse models.” The Anatomical Record (Special Issue: “New Concepts in Developing Brain Disorders--Autism”), 2011, Oct;294(10):1713-25. doi: 10.1002/ar.21318. Epub 2011 Sep 8. PMID: 21905241

Dow HC, Kreibich AS, Kaercher KA, Sankoorikal GM, Pauley ED, Lohoff FW, Ferraro TN, Li H, Brodkin ES.: “Genetic dissection of intermale aggressive behavior in BALB/cJ and A/J mice.” Genes, Brain and Behavior, 2011 Feb;10(1):57-68. doi: 10.1111/j.1601-183X.2010.00640.x. Epub 2010 Oct 5. PMID: 20731721

Brodkin ES.: “Social behavior phenotypes in fragile X syndrome, autism, and the Fmr1 knockout mouse: theoretical comment on McNaughton et al. (2008).” Behavioral Neuroscience, 2008, Apr;122(2):483-9. doi: 10.1037/0735-7044.122.2.483. Review. PMID: 18410188

Brodkin ES.: “BALB/c mice: low sociability and other phenotypes that may be relevant to autism.” Behavioural Brain Research, 2007, Jan 10;176(1):53-65. Epub 2006 Aug 4. Review. PMID: 16890300

Sankoorikal GM, Kaercher KA, Boon CJ, Lee JK, Brodkin ES.: “A mouse model system for genetic analysis of sociability: C57BL/6J versus BALB/cJ inbred mouse strains.” Biological Psychology, 2006, Mar 1;59(5):415-23. Epub 2005 Sep 30. PMID: 16199013

Brodkin ES.: “Quantitative trait locus analysis of aggressive behaviours in mice.” Novartis Foundation Symposium, 2005;268:57-69; discussion 69-77, 96-9. Review. PMID: 16206875

Brodkin ES, Hagemann A, Nemetski SM, Silver LM.: “Social approach-avoidance behavior of inbred mouse strains towards DBA/2 mice.” Brain Research, 2004, Mar 26;1002(1-2):151-7. PMID: 14988045