The GMP Vector Core produces gene therapy vectors intended for use in early stage clinical development. The Core works closely with clients, sponsors, and business manages and provides the necessary support for investigational drug applications and regulatory submissions.
William Chung, M.S.
William Chung has the Director of the CAROT Good Manufacturing Practices (GMP) Clinical Vector Core and earned a Molecular Cell Biology degree from University of California, Berkeley and a Medical Sciences degree from Boston University. He has had more than a dozen years of work experience in various regulated laboratory environments. The scope of his work has included analytical support in pharmaceutical companies, laboratory/project management in GLP-compliant contract laboratories, and oversight of assay validation and quality controls. At CAROT, he has developed the process for generating clinical grade recombinant viral vectors and using those processes, he has led more than a dozen different campaigns to generate reagents that have been used in clinical trials.
William Righter, B.S.
Bill Righter graduated from Temple University with a B.S. in Biology and gained extensive experience in both academia and biotechnology. He was recruited to CAROT in 2015 as a Research Technologist. At CAROT, he conducts GMP manufacture of clinical grade lentiviral and AAV recombinant viruses, and performs environmental monitoring and quality control testing.
Tiffany Kincaid, B.A.
Tiffany Kincaid is a Quality Assurance professional, with more than a decade of experience in Good Manufacturing Practices (GMP)-regulated environments. Her work has included manufacture of monoclonal antibodies, recombinant viral vectors, and gene therapy reagents for phase I/II clinical trials. She earned her degree from Indiana University of Pennsylvania in Biology and Chemistry and is currently completing her M.S. in Quality Assurance/Regulatory Affairs at Temple University.
Aaron M. Brodsky
Aaron Brodsky earned his B.S. in Chemistry with a minor in Biochemistry from University of Delaware and worked as an IPC chemist, computer systems coordinator, Associate Scientist in Chemical Repository and in Mammalian Mutations in the Toxicology Department at Merck (BioReliance) and at WuXi AppTec in the Viral Clearance Laboratory before being recruited to CAROT. At CAROT, he conducts GMP manufacture of clinical grade lentiviral and AAV recombinant viruses, and performs environmental monitoring and quality control testing. He is currently earning a Master of Chemical Sciences degree in his spare time.
Olga Lozynska M.S.
Olga Lozynska received her M.S. degree in Biochemistry from Kiev State University (Ukraine). She has >1,5 decades of experience in biomedical research, with projects spanning from cell and developmental biology to physiology, laser capture micro-dissection and drug discovery. Ms. Lozynska has participated in many CAROT research projects, including whole exome screening of patients and family members to identify novel genes and disease-causing mutations. Ms. Lozynska was recruited to the CAROT Good Manufacturing Practice (GMP) clinical vector core facility soon after it was built and has participated in more than a dozen different campaigns to generate recombinant viral vectors used in human clinical trials.