Andrew P. Steenhoff, MBBCh, DCH

Scholar

  •  Attending Physician | Division of Infectious Diseases at Children's Hospital
  •  Ethiopia | Botswana | Dominican Republic | Nigeria
  •   HIV/AIDS | Partnerships | Pediatrics | Tuberculosis

Languages: English (native), Zulu (basic), French (basic), Afrikaans (basic)

Bio statement

Dr. Andrew Steenhoff MBBCh, FAAP trained at the Univ. of the Witwatersrand, Johannesburg. After completing pediatric residencies at Chris-Hani Baragwanath Hospital & Albert Einstein Medical Center, Philadelphia, he did Infectious Diseases Fellowship at the Children’s Hospital of Philadelphia (CHOP), then was based in Botswana for 7.5 years as Associate Country Director & Research Director, Botswana-UPenn Partnership. In 7/2015, he was appointed Medical Director of CHOP’s Global Health Center. Andrew combines clinical, public health and research skills to improve pediatric outcomes in low and middle-income countries. His research focuses on pediatric infectious diseases with a particular interest in tuberculosis, HIV, pneumonia and gastroenteritis. Andrew is the author of over 100 peer-reviewed manuscripts and book chapters. He teaches and mentors students, residents and fellows in Botswana, the Dominican Republic and Philadelphia. He is an Assistant Professor of Pediatrics at UPenn, Adjunct Senior Lecturer, University of Botswana, and a member of the American Board of Pediatrics Global Health Task Force. 

Recent global health projects

"Partnerships for global child health" state of the art review - this was completed in collaboration with colleagues around the world and with the American Board of Pediatrics. The final product, which seeks to play a role in optimizing partnerships to improve global child health, was published in Pediatrics and can be accessed here: https://www.ncbi.nlm.nih.gov/pubmed/28931576 

Chair of the 2017 CHOP Global Health conference - this conference drew attention to the plight of immigrants and refugees, which is both a local global and a global global challenge. The conference brought together more than 170 experts from across the country and some form other countries to network, learn and advocate on this important topic. See http://www.chop.edu/events/pediatric-global-health-conference

Selected publications

  1. Pernica JM, Steenhoff AP, Mokomane M, Moorad B, Lechiile K, Smieja M, Mazhani L, Cheng J, Kelly MS, Loeb M, Stordal K, Goldfarb DM. (2017) Rapid enteric testing to permit targeted antimicrobial therapy, with and without Lactobacillus reuteri probiotics, for paediatric acute diarrhoeal disease in Botswana: A pilot, randomized, factorial, controlled trial.PLoS One. 9 Oct 2017; 12(10):e0185177. doi: 10.1371/journal.pone.0185177. 
  2. Reid MJA, Steenhoff AP, Thompson J, Gabaitiri L, Cary MS, Steele K, Mayisela S, Dickinson D, Ehrenkranz P, Friedman HM, Linkin DR (2017). Evaluation of the effect of cellular SMS reminders on consistency of antiretroviral therapy pharmacy pickups in HIV-infected adults in Botswana: a randomized controlled trial. Health Psychol Behav Med. 9 Jan 2017; 5(1):101-109. doi: 10.1080/21642850.2016.1271333.

  3. Steenhoff AP, Crouse HL, Lukolyo H, Larson CP, Howard C, Mazhani L, Pak-Gorstein S, Niescierenko ML, Musoke P, Marshall R, Soto MA, Butteris SM, Batra M; GH Task Force of the American Board of Pediatrics (2017).Partnerships for Global Child Health.Pediatrics. Oct 2017; 140(4). pii: e20163823. doi: 10.1542/peds.2016-3823.

  4. Handy LK, Maroudi S, Powell M, Nfila B, Moser C, Japa I, Monyatsi N, Tzortzi E, Kouzeli I, Luberti A, Theodoridou M, Offit P, Steenhoff AP, Shea JA, Feemster KA (2017). The impact of access to immunization information on vaccine acceptance in three countries. PLoS One. 3 Aug 2017; 12(8):e0180759. doi: 10.1371/journal.pone.0180759. 

  5. Gross R, Bellamy SL, Ratshaa B, Han X, Vujkovic M, Aplenc R, Steenhoff AP, Mosepele M, Moorthy G, Zuppa AF, Strom BL, Bisson GP (2017). CYP2B6 genotypes and early efavirenz-based HIV treatment outcomes in Botswana. AIDS. 24 Sep 2017; 31(15):2107-2113. doi: 10.1097/QAD.0000000000001593.

  6. Tenforde MW, Mokomane M, Leeme T, Patel RKK, Lekwape N, Ramodimoosi C, Dube B, Williams EA, Mokobela KO, Tawanana E, Pilatwe T, Hurt WJ, Mitchell H, Banda DL, Stone H, Molefi M, Mokgacha K, Phillips H, Mullan PC, Steenhoff AP, Mashalla Y, Mine M, Jarvis JN (2017). Advanced HIV disease in Botswana following successful antiretroviral therapy rollout: Incidence of and temporal trends in cryptococcal meningitis. Clin Infect Dis. 13 May 2017. doi: 10.1093/cid/cix430.

  7. Vujkovic M, Bellamy SL, Zuppa AF, Gastonguay M, Moorthy GS, Ratshaa BR, Han X, Steenhoff AP, Mosepele M, Strom BL, Aplenc R, Bisson GP, Gross R (2017). Brief Report: CYP2B6 516G>T Minor Allele Protective of Late Virologic Failure in Efavirenz-Treated HIV-Infected Patients in Botswana.J Acquir Immune Defic Syndr. 1 Aug 2017; 75(4):488-491. doi: 10.1097/QAI.0000000000001442.

  8. Arscott-Mills T, Masole L, Ncube R, Steenhoff AP (2017). Survey of health care worker knowledge about childhood tuberculosis in high-burden centers in Botswana. Int J Tuberc Lung Dis. 1 May 2017; 21(5):586-591. doi: 10.5588/ijtld.16.0668.

  9. Kelly MS, Surette MG, Smieja M, Pernica JM, Rossi L, Luinstra K, Steenhoff AP, Feemster KA, Goldfarb DM, Arscott-Mills T, Boiditswe S, Rulaganyang I, Muthoga C, Gaofiwe L, Mazhani T, Rawls JF, Cunningham CK, Shah SS, Seed PC (2017). The Nasopharyngeal Microbiota of Children With Respiratory Infections in Botswana. Pediatr Infect Dis J. 2017 Sep; 36(9):e211-e218. doi: 10.1097/INF.0000000000001607.

  10. Ravimohan S, Tamuhla N, Nfanyana K, Ni H, Steenhoff AP, Gross R, Weissman D, Bisson GP. Elevated Pre-Antiretroviral Therapy CD39+CD8+ T Cell Frequency Is Associated With Early Mortality in Advanced Human Immunodeficiency Virus/Tuberculosis Co-infection. Clin Infect Dis. 15 May 2017; 64(10):1453-1456. doi: 10.1093/cid/cix155.