Center for
Global Health

Scholar

Languages: English, Spanish

BIO STATEMENT

Dr. Chirinos is a Professor of Medicine and Co-Director of the Clinical Research T32 Training Program in Cardiovascular Biology and Medicine. He is the President of the North American Artery Society. He is also an adjunct Faculty member at the University of Ghent in Belgium. His research program is focused on the role of arterial stiffness and pulsatile hemodynamics in cardiovascular disease and mechanisms of heart failure with preserved ejection fraction. He co-leads a Global Heart Failure biomarker consortium investigating proteomics in heart failure. He has multiple international collaborations and has led international randomized trials.

Recent Global Health Projects

• I led 2 international multicenter trials testing therapeutic strategies related to the intersection of COVID-19 and cardiovascular disease.
• I'm co-chair of the Global Heart Failure Biomarker Consortium, and a Steering Committee Member of HeartShare. Both of these multicenter consortia are focused on the study of heart failure with preserved ejection fraction (HFpEF).
• I maintain an active collaboration with the Asklepios investigators studying cardiovascular aging at U. of Ghent.

Select Publications

Dib MJ, Azzo JD, Zhao L, Salman O, Gan S, De Buyzere ML, De Meyer T, Ebert C, Gunawardhana K, Liu L, Gordon D, Seiffert D, Ching-Pin C, Zamani P, Cohen JB, Pourmussa B, Kun S, Gill D, Burgess S, van Empel V, Richards AM, Dennis J, Javaheri A, Mann DL, Cappola TP, Rietzschel E, Chirinos JA. Proteome-Wide Genetic Investigation of Large Artery Stiffness. JACC Basic Transl Sci. 2024 Aug 21;9(10):1178-1191. doi: 10.1016/j.jacbts.2024.05.017. PMID: 39534640; PMCID: PMC11551872.

Cohen JB, Hanff TC, William P, Sweitzer N, Rosado-Santander NR, Medina C, Rodriguez-Mori JE, Renna N, Chang TI, Corrales-Medina V, Andrade-Villanueva JF, Barbagelata A, Cristodulo-Cortez R, Díaz-Cucho OA, Spaak J, Alfonso CE, Valdivia-Vega R, Villavicencio-Carranza M, Ayala-García RJ, Castro-Callirgos CA, González-Hernández LA, Bernales-Salas EF, Coacalla-Guerra JC, Salinas-Herrera CD, Nicolosi L, Basconcel M, Byrd JB, Sharkoski T, Bendezú-Huasasquiche LE, Chittams J, Edmonston DL, Vasquez CR, Chirinos JA. Continuation versus discontinuation of renin-angiotensin system inhibitors in patients admitted to hospital with COVID-19: a prospective, randomised, open-label trial. Lancet Respir Med. 2021 Mar;9(3):275-284. doi: 10.1016/S2213-2600(20)30558-0. Epub 2021 Jan 7. PMID: 33422263; PMCID: PMC7832152.

Chirinos JA, Lopez-Jaramillo P, Giamarellos-Bourboulis EJ, Dávila-Del-Carpio GH, Bizri AR, Andrade-Villanueva JF, Salman O, Cure-Cure C, Rosado-Santander NR, Cornejo Giraldo MP, González-Hernández LA, Moghnieh R, Angeliki R, Cruz Saldarriaga ME, Pariona M, Medina C, Dimitroulis I, Vlachopoulos C, Gutierrez C, Rodriguez-Mori JE, Gomez-Laiton E, Cotrina Pereyra R, Ravelo Hernández JL, Arbañil H, Accini-Mendoza J, Pérez-Mayorga M, Milionis C, Poulakou G, Sánchez G, Valdivia-Vega R, Villavicencio-Carranza M, Ayala-García RJ, Castro-Callirgos CA, Alfaro Carrasco RM, Garrido Lecca Danos W, Sharkoski T, Greene K, Pourmussa B, Greczylo C, Ortega-Legaspi J, Jacoby D, Chittams J, Katsaounou P, Alexiou Z, Sympardi S, Sweitzer NK, Putt M, Cohen JB; FERMIN Investigators. A randomized clinical trial of lipid metabolism modulation with fenofibrate for acute coronavirus disease 2019. Nat Metab. 2022 Dec;4(12):1847-1857. doi: 10.1038/s42255-022-00698-3. Epub 2022 Nov 7. PMID: 36344766; PMCID: PMC9640855.

Last Updated: 16 December 2024