Mohan S. Narasimhamurthy, MD

Associate Scholar

  •  Resident, Pathology & Laboratory Medicine | University of Pennsylvania
  •  Botswana | India
  •   Oncology | Pathology | Training Laboratory Professionals

Languages: English, Hindi, Kannada

BIO STATEMENT

I practiced pathology for nine years in Botswana in various capacities, including assistant program director of the pathology residency program at the University of Botswana and the National Health Laboratory. I was involved in developing a pathology residency program, laboratory accreditation, scaling up diagnostic services with the introduction of immunohistochemistry, and setting up multidisciplinary tumor board meetings. I also initiated rapid on-site evaluation in FNA clinics, which received the Best Public Service Initiative from the Ministry of Health, Botswana, in 2017. I have taught medical students, pathology residents, laboratory scientists, full-bright scholars, and MPhil students. In addition, I participated in several projects, including HPV genotyping and breast cancer-related studies, and published several papers.
I was the informal technical committee member for WHO to develop a technical package on strengthening and scaling-up services for the management of invasive cervical cancer. I also contributed to drafting and reviewing the WHO Guide for establishing a pathology laboratory in the context of cancer control and WHO-IAEA Framework for Setting up a Comprehensive Cancer Centre, 2021.

Recent Global Health Projects

1. The impact of neoadjuvant chemotherapy on breast cancer in HIV and looking at pathologic response rate.


2. I reviewed the framework guidelines for laboratory protocols in setting up a comprehensive cancer center


3. Cervical cancer screening in Nepal, the challenges related to cytology screening and HPV DNA testing. The manuscript is in the final stages of acceptance in Frontiers of Public Health.

Publication 

Promoter Hypermethylation Analysis of Host Genes in Cervical Cancer Patients With and Without Human Immunodeficiency Virus in Botswana. L Tawe, S Grover, N Zetola, ES Robertson, S Gaseitsiwe, S Moyo, Mohan Narasimhamurthy, Frontiers in Oncology 11, 509.2021
https://pubmed.ncbi.nlm.nih.gov/33718129/

Breast Cancer Pathology Turnaround Time in Botswana: Yehoda M. Martei, Mohan Narasimhamurthy, Pooja Prabhakar, Jeré Hutson, Surbhi Grover et al, Journal of Global Oncology DOI:10.1200/JGO.17.00090, 2020
https://ascopubs.org/doi/full/10.1200/JGO.17.00090

Martei YM, Grover S, Narasimhamurthy M, Setlhako DI, Ayane GN, Ralefala TB, Chiyapo SP, Gross R, DeMichele A, Shulman LN: Relative dose intensity and pathologic response rates in HIV-infected and HIV-uninfected breast cancer patients who received neoadjuvant chemotherapy. Journal of Clinical Oncology 18(15 Suppl e19140), 2020.
https://pubmed.ncbi.nlm.nih.gov/35584347/


Narasimhamurthy, M., Bhatia, R.K., Martei, Y.M. et al. Report of clinico-pathological features of breast cancer in HIV-infected and uninfected women in Botswana. Infect Agents Cancer 14, 28 (2019). https://doi.org/10.1186/s13027-019-0245-6
https://infectagentscancer.biomedcentral.com/articles/10.1186/s13027-019-0245-6

Multidisciplinary gynecologic oncology clinic in Botswana: a model for multidisciplinary oncology care in low-and middle-income settings. S Grover, SP Chiyapo, P Puri, M Narasimhamurthy, BE Gaolebale, et al: Journal of global oncology 2017; 3 (5), 666-670
https://pubmed.ncbi.nlm.nih.gov/29094103/

WHO-IAEA Framework for Setting up a Comprehensive Cancer Centre, 2021
https://www.iaea.org/publications/15052/setting-up-a-cancer-centre-a-who-iaea-framework