The PennPET Explorer is an extended field-of-view PET scanner designed for clinical and research uses. Potential uses include total-body dynamic imaging, high throughput patient imaging, and imaging novel PET tracers to better understand cancers. The PennPET Explorer boasts a 250 ps timing resolution, a 4.0 mm spatial resolution, and is built as a modular configuration that can be extended over time depending on applications.
Advantages of the long axial FOV scanner include
- Enhance the ability to image in vivo systems simultaneously across multiple organs
- Reduce administered dose and imaging time
- Improve image quality and accuracy
- Dynamically image whole-body bio-distribution studies for drug dosing, along with a variety of other applications not possibly with standard, commercial PET/CT scanners
This work is part of the EXPLORER consortium including the University of California, Davis.
PennPET Explorer papers are in JNM!!
A.R. Pantel, V. Viswanath, M.E. Daube-Witherspoon, J.G. Dubroff, G. Muehllehner, M.J. Parma, D.A. Pryma, E.K.Schubert, D.A. Mankoff, J.S. Karp. PennPET Explorer: Human imaging on a whole-body imager. J Nucl Med, vol. 61, pp. 144-151, 2020.
J.S. Karp, V. Viswanath, M.J. Geagan, G. Muehllehner, A.R. Pantel, M.J. Parma, A.E. Perkins, J.P. Schmall, M.E. Werner, M.E. Daube-Witherspoon. PennPET Explorer: Design and preliminary performance of a whole-body imager. J Nucl Med, vol. 61, pp. 136-143, 2020.
Detectability paper accepted to PMB!!
Viswanath V, Daube-Witherspoon ME, Karp JS, Surti S. Numerical observer study of lesion detectability for a long axial field-of-view whole-body PET imager using the PennPET Explorer. Physics in Medicine and Biology (Accepted).