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PICI @ Penn Research Projects
- Define the Intersection of CARs and Oncolytic Viruses
- Development of engineered T cell therapy for cancer in companion animals
- Identifying and dissecting the anti-tumor regulation networks of CAR T cells in Pancreatic Cancer and Chronic Lymphoblastic Leukemia using CRISPR-based genetic approaches
- The Role of CD40 Activation in Tumor Immunology and Immunotherapy
- Development of Chimeric Antigen Receptor T Cells Against T Cell Lymphoma and Leukemia Using CRISPR/Cas9 Gene-editing
- Role of Antigen Strength in Regulating Tumor
- Clinical and Immune Evaluation of Establishing T Cell Immunity In Immunologically Cold Tumors
- In Vitro T Cell Exhaustion Modeling and High Throughput Screening
- Checkpoint Blockade Cellular and Molecular Mechanisms
- Human Immunoprofiling and Mechanisms
- Basic Mechanisms of T Cell Exhaustion
- Tissue Engineering Approaches for Tumor Immunotherapy
- RadVax: Cellular and molecular mechanisms of interaction between radiation and checkpoint blockade
- Novel Immune Prevention and Therapies For Cancer
- Neoantigen-specific Adoptive T cell Therapies in Cancer
- Plasma banking for immunotherapy monitoring
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PICI@Penn Cancer Clinical Immunotherapy Trials
- Safety and Efficacy of APX005M With Gemcitabine and Nab-Paclitaxel With or Without Nivolumab in Patients With Previously Untreated Metastatic Pancreatic Adenocarcinoma
- Mature Dendritic Cell Vaccination Against Mutated Antigens in Patients with Advanced Melanoma
- Ipilimumab vs Ipilimumab Plus Nivolumab in Patients With Stage III-IV Melanoma Who Have Progressed or Relapsed on PD-1 Inhibitor Therapy
- NY-ESO-1-redirected CRISPR (TCRendo and PD1) Edited T Cells (NYCE T Cells)
- Technology Transfer
- Search Penn Cancer Clinical Trials
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- Benci Cell 2016
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- Data Project Meetings 2021
- Our Work