Abstracts
- Yang S, Lee J, Liu X, Baik JY, Li D, Chen T, Shen L. (2024) Inferring phenotypes from tabular genotype data with pre-trained Large Language Model. ASHG’24: American Society of Human Genetics, 2024-A-1751-ASHG. Denver, CO, November 5-9, 2024. (Reviewers’ Choice Abstract, top 10%)
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Bao J, Mu S, Xu H, Mamourian E, Zhan Q, Erus G, Shou H, Davatzikos C, Zhang Q, Wen J, Long Q, Shen L. (2024) The genetic etiology of Alzheimer’s disease mediated by regional brain gray matter densities. ASHG’24: American Society of Human Genetics, 2024-A-1751-ASHG. Denver, CO, November 5-9, 2024
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Baik JY, Yang S, Liu X, Ning X, Kim D, Shen L. (2024) Identifying risk variants in the 3’ untranslated regions affecting Alzheimer’s Disease by integrative analysis of eQTL, microRNA, and protein binding profiling. ASHG’24: American Society of Human Genetics, 2024-A-1595-ASHG. Denver, CO, November 5-9, 2024.
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Xu J, Wei T, Hou B, Orzechowski P, Yang S, Demiris G, Shen L. (2024) MentalGPT: Harnessing AD for compassionate mental health support. AMIA'24: AMIA 2024 Annual Symposium, November 9-11, 2024, in press. (Podium Abstract, Oral Presentation)
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Feng Y, Hou B, Klein A, O'Connor K, Chen J, Mondragón A, Yang S, Gonzalez-Hernandez G, Shen L. (2024) Exploring Semantic Topics in Dementia Caregiver Tweets. AAIC'24: Alzheimer's Association Int Conf on Alzheimer's Disease, Lightning Presentation Round (LRP) Poster 93035. Philadelphia and Online, July 28 - August 1, 2024.
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Mamourian E, Bao J, Cui Y, Huang H, Saykin AJ, Thompson PM, Moore JH, Ritchie MD, Kim D, Davatzikos C, Shen L. (2024) Genetic associations with amyloid, tau, and neurodegeneration: an ADSP neuroimaging study. AAIC'24: Alzheimer's Association Int Conf on Alzheimer's Disease, Poster 94870. Philadelphia and Online, July 28 - August 1, 2024.
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Xu J, Wei T, Hou B, Demiris G, Shen L. (2024) Revolutionizing Dementia Care: Enhancing Talk Therapy with Fine-Tuned Large Language Models Using GPT Self-Generated Data. AAIC'24: Alzheimer's Association Int Conf on Alzheimer's Disease, Poster 93496. Philadelphia and Online, July 28 - August 1, 2024.
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Xu H, Mu S, Bao J, Davatzikos C, Shou H, Shen L. (2024) Physical activity pattern mediating the relationship between genetic variants and AD-like brain atrophy. AAIC'24: Alzheimer's Association Int Conf on Alzheimer's Disease, Poster 92392. Philadelphia and Online, July 28 - August 1, 2024.
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Garai S, Liu M, Xu F, Goñi J, Duong-Tran D, Zhao Y, Shen L, for the ADNI. (2024) Effect of brain network scale on Persistence Cycles: An ADNI comparative study. AAIC'24: Alzheimer's Association Int Conf on Alzheimer's Disease, Poster 92343. Philadelphia and Online, July 28 - August 1, 2024.
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Yang S, Wang A, Bao J, Mu S, Feng Y, Wen Z, Baik JY, Wen J, Hou B, Wang R, Huang H, Saykin AJ, Thompson PM, Davatzikos C, Shen L, for the ADNI and AI4AD. (2024) ‘Diet’ deep canonical correlation analysis for high-dimensional genetics study of brain imaging phenotypes in Alzheimer’s disease. AAIC'24: Alzheimer's Association Int Conf on Alzheimer's Disease, Poster 92330. Philadelphia and Online, July 28 - August 1, 2024.
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Hou B, Wen Z, Bao J, Zhang R, Tong B, Yang S, Wen J, Cui Y, Moore JH, Saykin AJ, Huang H, Thompson PM, Ritchie MD, Davatzikos C, Shen L, Alzheimer's Disease Neuroimaging Initiative. (2024) Interpretable Deep Clustering Survival Machines for Alzheimer's Disease Risk Groups Discovery. AAIC'24: Alzheimer's Association Int Conf on Alzheimer's Disease, Poster 92319. Philadelphia and Online, July 28 - August 1, 2024.
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Mu S, Rathore S, Bao J, Yang S, Hooli B, Shen L, for the ADNI. (2024) Genome-wide mediation analysis reveals amyloid and tau imaging genetics patterns in Alzheimer’s Disease. AAIC'24: Alzheimer's Association Int Conf on Alzheimer's Disease, Poster 89710. Philadelphia and Online, July 28 - August 1, 2024.
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Jung S-H, Woerner J, Lee D-g, Nam Y, Shen L, Won H-H, Kim D. (2024) Polygenic score-wide association study of comorbidities to incident dementia. AAIC'24: Alzheimer's Association Int Conf on Alzheimer's Disease, Poster 95150. Philadelphia and Online, July 28 - August 1, 2024.
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Lee D-g, Jung S-H, Shen L, Kim D. (2024) Integrative Analysis of Genetic Network and Brain Imaging using Generative Models for Alzheimer’s Disease Prediction. AAIC'24: Alzheimer's Association Int Conf on Alzheimer's Disease, Poster 91830. Philadelphia and Online, July 28 - August 1, 2024.
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Wang S, Wang Y, Xu F, Shen L, Zhao Y. (2024) Sex-specific topological structure associated with dementia identified via latent space network analysis. AAIC'24: Alzheimer's Association Int Conf on Alzheimer's Disease, Poster 90404. Philadelphia and Online, July 28 - August 1, 2024.
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Moore A, Bradford Y, Kumar R, Venkatesh R, Shivakumar M, Bao J, Shen L, Kim D, Ritchie MD. (2024) Known and novel genes significant to AD across tissues may help to uncover comprehensive changes of disease. AAIC'24: Alzheimer's Association Int Conf on Alzheimer's Disease, Poster 87088. Philadelphia and Online, July 28 - August 1, 2024.
- Nam Y, Woerner J, Jung S-H, Suh EH, Shou H, Shen L, Kim D. (2024) BrainNetScore: Enhancing Alzheimer's disease risk prediction using genetic-guided brain volumetric phenotype network. AAIC'24: Alzheimer's Association Int Conf on Alzheimer's Disease, Poster 84351. Philadelphia and Online, July 28 - August 1, 2024.
- Nguyen N, Hou T, Shen L, Duong-Tran D. (2024) Theta-alpha aperiodic dynamics covary with persistence homological scaffolds of hemodynamic networks. OHBM’24: Organization for Human Brain Mapping Ann Meeting, Poster 3818. Seoul, South Korea, July 23-27, 2024.
- Nam Y, Woerner J, Jung S-H, Suh E, Shou H, Shen L, Kim D. (2024) Enhancing Alzheimer's disease prediction using genetic-guided brain volumetric phenotype network. OHBM’24: Organization for Human Brain Mapping Ann Meeting, Poster 3818. Seoul, South Korea, July 23-27, 2024.
- Suh E, Nho K, Shen L, Saykin A, Kim D. (2024) Metabolomic-based risk score informed by neuroimaging biomarkers improves Alzheimer’s disease risk. OHBM’24: Organization for Human Brain Mapping Ann Meeting, Poster 3818. Seoul, South Korea, July 23-27, 2024.
- An S, Shen L, Park SH. (2024) Motor imagery EEG signal generation from resting-state signal. EMBC’24: 46th Annual International Conference of the IEEE Engineering in Medicine & Biology Society. Orlando, Florida, USA, July 15-19, 2024.
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Yang S, Sha J, Qu J, Wang X, Feng Y, Kim D, Davatzikos C, Shen L. (2023) Diet Factorization Net: efficient model parameterization for high dimensional genomics data to predict brain imaging trait of Alzheimer's disease. AMIA’23: AMIA Annual Symposium 2023, New Orleans, LA, November 11-15, 2023.
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Suh E, Shivakumar M, Naj A, Saykin A, Ritchie M, Shen L, Kim D. (2023) Improved late-onset Alzheimer’s disease risk prediction and stratification through a combined genetic risk score of common and rare variants. ASHG’23: American Society of Human Genetics, Platform Session 067: Genetic analysis of neurological disorders, Washington, DC, November 1-5, 2023.
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Lee DG, Jung SH, Shen L, Kim D. (2023) Predicting neurodegenerative disease risk using feature propagation on snp network with brain imaging endophenotypes. ASHG’23: American Society of Human Genetics, PB1728, Washington, DC, November 1-5, 2023.
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Shivakumar M, Jung SH, Suh E, Bao J, Shen L, Kim D. (2023) Enhancing Alzheimer’s disease prediction and portability through integration of transcription wide association study and polygenic risk scores in diverse populations. ASHG’23: American Society of Human Genetics, PB1449, Washington, DC, November 1-5, 2023.
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Machado-Reyes D, Chao H, Hahn J, Shen L, Yan P. (2023) A combined structural-functional classification of schizophrenia using hippocampal volume plus fMRI activation. BMES'23: Biomedical Engineering Society 2023 Annual Meeting, Poster # 238, Seattle, WA, October 11-24, 2023.
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Jung SH, Won HH, Shen L, Kim D. (2023) Multi-task transfer learning-based polygenic risk score modeling for identifying individuals with high risk of Alzheimer’s disease. ISMB/ECCB’23: The 31st Annual Intelligent Systems For Molecular Biology and the 22nd Annual European Conference on Computational Biology, Lyon, France, July 23-27, 2023.
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Lee BN, Kim M, Wang Z, Shen L. (2023) Genetic association study and functional annotation of highly-heritable brain entropy traits. OHBM’23: Organization for Human Brain Mapping Ann Meeting, Poster 2017. Montréal, Canada, July 22-26, 2023.
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Ballard JL, Shen L. (2023) Identifying subtypes of Alzheimer’s disease based on patient trajectory clustering. OHBM’23: Organization for Human Brain Mapping Ann Meeting, Poster 1467. Montréal, Canada, July 22-26, 2023.
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Garai S, Duong-Tran D, Xu F, Zhao Y, Shen L. (2023) Vertex Importance for forming Co-cycles and its correlation with cognitive performance. OHBM’23: Organization for Human Brain Mapping Ann Meeting, Poster 728. Montréal, Canada, July 22-26, 2023.
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Duong-Tran D, Kaufmann R, Wang X, Amico E, Kaplan A, Petri G, Zhao Y, Goñi J, Chung M, Shen L. (2023) On topological landscapes of human brain functional networks. OHBM’23: Organization for Human Brain Mapping Ann Meeting, Poster 341. Montréal, Canada, July 22-26, 2023.
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Nguyen NC, Shen L, Duong-Tran D. (2023) Thalamo-cortical mass model unveils aging-like slow wave-spindle dynamics. OHBM’23: Organization for Human Brain Mapping Ann Meeting, Poster 714. Montréal, Canada, July 22-26, 2023.
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Umair M, Shen L, Duong-Tran D, Wang X. (2023) Subject and Task Fingerprint using Dynamics Reconstruction from fMRI Time-series Data. OHBM’23: Organization for Human Brain Mapping Ann Meeting, Poster 546. Montréal, Canada, July 22-26, 2023.
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Wang S, Wang Y, Xu FH, Shen L, Zhao Y. (2023) Identifying gender based neuromarkers of alzheimer's disease using ABC network model. OHBM’23: Organization for Human Brain Mapping Ann Meeting, Poster 688. Montréal, Canada, July 22-26, 2023.
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Wen J, Yang Z, Skampardoni I, Pian MD, Erus G, Mamourian E, Cui Y, Zhao B, Nasrallah IM, Toga A, Shou H, Shen L, Davatzikos C. (2023) Genetic correlations between brain structural covariance and brain disorders. OHBM’23: Organization for Human Brain Mapping Ann Meeting, Poster 2024. Montréal, Canada, July 22-26, 2023.
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Wen J, Yang Z, Skampardoni I, Pian MD, Erus G, Mamourian E, Cui Y, Zhou Z, Zhao B, Toga A, Shou H, Shen L, Davatzikos C. (2023) Brain age prediction: a comparative study of three imaging modalities and four machine learning models OHBM’23: Organization for Human Brain Mapping Ann Meeting, Poster 232. Montréal, Canada, July 22-26, 2023.
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Shen L. (2023) Genome-Wide Mediation Analysis Reveals the Genetic Underpinnings of the Neuromorphometric Endophenotypes of Alzheimer’s Disease. AAIC'23: Alzheimer's Association Int Conf on Alzheimer's Disease, Poster 74776. Amsterdam, Netherlands and Online, July 16-20, 2023.
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Lee BN, Bao J, Tong B, Risacher SL, Saykin AJ, Moore JH, Kim D, Davatzikos C, Long Q, Ritchie MD, Shen L. (2023) Mediation Analysis Identifies Amyloid Imaging Genetic Patterns for Cognitive Outcomes in Alzheimer's Disease. AAIC'23: Alzheimer's Association Int Conf on Alzheimer's Disease, Poster 78634. Amsterdam, Netherlands and Online, July 16-20, 2023.
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Mu S, Bao J, Wen Z, Yang S, Hohman TJ, Huang H, Thompson PM, Saykin AJ, Davatzikos C, Kim D, Shen L, for the Alzheimer's Disease Neuroimaging Initiative and the AI4AD Initiative. (2023) Genome-wide association study on Alzheimer’s disease related cognitive, fluid, and neuropathology biomarkers in the African American population. AAIC'23: Alzheimer's Association Int Conf on Alzheimer's Disease, Poster 82878. Amsterdam, Netherlands and Online, July 16-20, 2023.
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Lee D-g, Jung S-H, Park S, Shen L, Shin H, Kim D, for the Alzheimer’s Disease Neuroimaging Initiative. (2023) NetPRISBI-AD: Network-based Polygenic Risk Scoring model with Brain Imaging for Alzheimer’s Disease. AAIC'23: Alzheimer's Association Int Conf on Alzheimer's Disease, Poster 79379. Amsterdam, Netherlands and Online, July 16-20, 2023.
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Jung S-H, Lee D-g, Shen L, Kim D. (2023) The potential utility of genetic susceptibility to life course modifiable factors for dementia prevention. AAIC'23: Alzheimer's Association Int Conf on Alzheimer's Disease, Poster 73780. Amsterdam, Netherlands and Online, July 16-20, 2023.
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Wen J, Yang Z, Skampardoni I, Pian MD, Erus G, Mamourian E, Cui Y, Zhao B, Nasrallah IM, Toga AW, Shou H, Shen L, Davatzikos C. (2023) Novel genomic loci shape two neuroanatomical dimensions of AD in non-demented populations. AAIC'23: Alzheimer's Association Int Conf on Alzheimer's Disease, Poster 71262. Amsterdam, Netherlands and Online, July 16-20, 2023.
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Yang Z, Wen J, Abdulkadir A, Cui Y, Erus G, Mamourian E, Melhem R, Srinivasan D, Govindarajan ST, Chen J, Habes M, Masters CL, Maruff P, Fripp J, Ferrucci L, Albert MS, Johnson SC, Morris JC, LaMontagne P, Marcus DS, Benzinger TLS, Wolk DA, Shen L, Bao J, Resnick SM, Tosun D, Shou H, Nasrallah IM, Davatzikos C, the Alzheimer’s Disease Neuroimaging Initiative, the Preclinical AD Consortium, the Baltimore Longitudinal Study of Aging, the iSTAGING study. (2023) Discovering Alzheimer’s disease subtypes with imaging and genetic signatures via multi-view weakly-supervised deep clustering. AAIC'23: Alzheimer's Association Int Conf on Alzheimer's Disease, Poster 75766. Amsterdam, Netherlands and Online, July 16-20, 2023.
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Skampardoni I, Nasrallah IM, Wen J, Cui Y, Abdulkadir A, Yang Z, Erus G, Mamourian E, Singh A, Shou H, Shen L, Nikita K, Davatzikos C, iSTAGING consortium. (2023) Genetic heterogeneity of structurally-defined brain morphologic patterns within cognitively unimpaired individuals. AAIC'23: Alzheimer's Association Int Conf on Alzheimer's Disease, Lightning Presentation Round (LPR) Poster 77195. Amsterdam, Netherlands and Online, July 16-20, 2023.
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Sahelijo N, Rajagopalan P, Priyadarshi D, Goldstein D, Nho K, Shen L, Huang H, Davatzikos C, Saykin AJ, Thompson PM, Jun GR. (2023) Cell-Based Genetic Subtypes Predict Neuroimaging Biomarkers and Clinical Conversion to Alzheimer’s Disease. AAIC'23: Alzheimer's Association Int Conf on Alzheimer's Disease, Featured Research Session (FRS) 73768. Amsterdam, Netherlands and Online, July 16-20, 2023.
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Sahelijo N, Rajagopalan P, Priyadarshi D, Goldstein D, Nho K, Shen L, Huang H, Davatzikos C, Saykin AJ, Thompson PM, Jun GR. (2023) Cell-Based Genetic Subtypes Predict Neuroimaging Biomarkers and Clinical Conversion to Alzheimer’s Disease. AIC'23: Alzheimer’s Imaging Consortium (AIC) Preconference, Poster 81629. Amsterdam, Netherlands and Online, July 15, 2023.
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Wei T, Yang S, Tarzanagh DA, Bao J, Xu J, Orzechowski P, Wagenaar JB, Long Q, Shen L. (2023) Clustering Alzheimer’s Disease Subtypes via Similarity Learning and Graph Diffusion. ICIBM’23: Int Conf on Intelligent Biology and Medicine. Tampa, FL, USA, July 16-19, 2023. (Oral Presentation)
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Shen L, Chen J, Lu Y, Lonita M, Hassinger K, Mckeague ML, Pattekar A, Greenplate AR, Wherry EJ. (2023) Cyto-UNET - A deep learning method for automated cytometric data pre-gating. CYTO 2023: The Congress for the International Society for the Advancement of Cytometry, Montreal, Canada, May 20-24, 2023. (Oral Presentation)
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Xu J, Xie Y, Zhang Y, Pala D, Shen L. (2023) Identification of the most determinant demographic and biological factors for the phenotypic and chronological age difference prediction in the NHANES cohort. AMIA-IS’23: AMIA Informatics Summit, pp 791-792, Seattle, WA, March 13-16, 2023. (Podium Abstract, Oral Presentation)
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Shen L. (2023) Integrating imaging and omics data for gene discovery in Alzheimer’s disease. ENAR’23: International Biometric Society Eastern North American Region (ENAR) 2023 Spring Meeting, Nashville, TN, March 19-22, 2023.
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Suh EH, Lee G, Jung SH, Wen W, Shen L, Kim D. (2022) Integrating common and rare variants into a genetic risk score for Alzheimer’s disease risk prediction. ASHG’22: American Society of Human Genetics, Los Angeles, CA, October 25-29, 2022.
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Wu R, Bao J, Kim M, Saykin AJ, Moore JH, Shen L. (2022) Mining high-level imaging genetic associations via clustering AD candidate variants with similar brain association patterns. ICIBM’22: Int. Conf. on Intelligent Biology and Medicine, Philadelphia, PA, USA, August 7-9, 2022.
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Wen Z, Bao J, Yang S, Kim M, Saykin AJ, Zhao Y, Shen L, and for the Alzheimer’s Disease Neuroimaging Initiative. (2022) Quantifying modality-specific brain signatures for cognitive traits in Alzheimer’s disease. ICIBM’22: Int. Conf. on Intelligent Biology and Medicine, Philadelphia, PA, USA, August 7-9, 2022.
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Lee B, Bao J, Zaranek SW, Chen J, Cui Y, Wen J, Yang S, Huang H, Saykin AJ, Thompson PM, Kim D, Davatzikos C, Zaranek AW, Shen L, for the ADNI and AI4AD initiative. (2022) Genome-wide association study using novel tiling array identifies genomic subsequences associated with Alzheimer’s disease quantitative traits. ICIBM’22: Int. Conf. on Intelligent Biology and Medicine, Philadelphia, PA, USA, August 7-9, 2022.
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Tong B, Feng Y, Wang X, Ritchie M, Moore J, Urbanowicz R, Shen L. (2022) Exploring automated machine learning for alzheimer’s disease classification and amyloid imaging biomarker discovery using STREAMLINE. ICIBM’22: Int. Conf. on Intelligent Biology and Medicine, Philadelphia, PA, USA, August 7-9, 2022.
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Pala D, Lee B, Ning X, Kim D, Shen L. (2022) Identifying stage-specific imaging genetic patterns in Alzheimer’s disease. ICIBM’22: Int. Conf. on Intelligent Biology and Medicine, Philadelphia, PA, USA, August 7-9, 2022.
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Yang S, Sha J, Liu K, Garai S, Bao J, Wen Z, Ng RT, Shen L. (2022) Predicting sequence specificities of experimentally unexplored RNA-binding proteins via optimizing the evolutionary correlation. ICIBM’22: Int. Conf. on Intelligent Biology and Medicine, Philadelphia, PA, USA, August 7-9, 2022.
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Yu J, Chen Y, Shen L, He L. (2022) Tensor-based multi-modality multi-target regression for Alzheimer’s disease diagnosis. ICIBM’22: Int. Conf. on Intelligent Biology and Medicine, Philadelphia, PA, USA, August 7-9, 2022.
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TumSuden S, Lee BN, Kim J, Ning X, Kim D, Shen L, for the ADNI (2022) Metabolite QTL analysis of ROSMAP and ADNI prioritized sequencing data identifies C14:2 genetic locus on Chr 2. AAIC'22: Alzheimer's Association Int Conf on Alzheimer's Disease, San Diego, USA and Online, July 31 - August 4, 2022.
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Bao J, Lee BN, Zaranek SW, Lee M, Shivakumar M, JunhaoWen, Chen J, Wen Z, Yang S, Huang H, Saykin AJ, Thompson PM, Davatzikos C, Kim D, Zaranek AW, Shen L, for the ADNI and AI4AD. (2022) Genetic association study of Alzheimer’s disease through whole genome tiling analysis. AAIC'22: Alzheimer's Association Int Conf on Alzheimer's Disease, San Diego, USA and Online, July 31 - August 4, 2022.
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Lee M, Lee BN, Zaranek SW, Bao J, Yang S, Jung S-H, Huang H, Saykin AJ, Thompson PM, Davatzikos C, Kim D, Zaranek AW, Shen L, for the ADNI. (2022) Machine learning for Alzheimer’s disease classification from genomic tiling variants. AAIC'22: Alzheimer's Association Int Conf on Alzheimer's Disease, San Diego, USA and Online, July 31 - August 4, 2022.
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Wu RR, Bao J, Kim M, Saykin AJ, Moore JH, Shen L, for the ADNI. (2022) Multigraph cluster analysis of AD candidate genes via human brain mapping. AAIC'22: Alzheimer's Association Int Conf on Alzheimer's Disease, San Diego, USA and Online, July 31 - August 4, 2022.
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Lee G, Suh EH, Jung S-H, Wen Z, Shen L, Kim D, for the ADNI. (2022) Developing an oligogenic risk score for Alzheimer’s disease (adORS). AAIC'22: Alzheimer's Association Int Conf on Alzheimer's Disease, San Diego, USA and Online, July 31 - August 4, 2022.
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Wen J, Cui Y, Yang Z, Bao J, Chen J, Erus G, Abdulkadir A, Mamourian E, Singh A, Yang S, Fan Y, Saykin AJ, Thompson PM, Jun GR, Ritchie MD, Shen L, Wolk DA, Shou H, Nasrallah IM, Davatzikos C. (2022) Genetic heterogeneity of four MCI/AD neuroanatomical dimensions discovered via deep learning. AAIC'22: Alzheimer's Association Int Conf on Alzheimer's Disease, San Diego, USA and Online, July 31 - August 4, 2022.
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Sahelijo N, Hu J, Priyadarshi D, Panitch R, Shen L, Thompson PM, Saykin AJ, Huang H, Nho K, Crane PK, Davatzikos C, Jun GR. (2022) Cell-level transcriptomic network analysis provides insights into distinct biological mechanisms for Alzheimer’s disease enabling targeted drug repositioning. AAIC'22: Alzheimer's Association Int Conf on Alzheimer's Disease, San Diego, USA and Online, July 31 - August 4, 2022.
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Yang S, Sha J, Garai S, Liu K, Bao J, Wen Z, Ng RT, Shen L. (2022) Correlated evolution-guided binding sequence specificity predictions for experimentally unexplored RNA-binding proteins. ISMB’22: 30th Conference on Intelligent Systems for Molecular Biology, Madison, USA and Online, July 10-14, 2022.
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Xu F, Garai S, Chung M, Caciagli L, Saykin AJ, Bassett DS, Shen L. (2022) Identifying topological changes of structural connectome in MCI and AD through persistent homology. OHBM’22: Organization for Human Brain Mapping Ann Meeting, Glasgow, Scotland, June 19-23, 2022.
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Kim J, Jung SH, Nho K, Shen L, Sohn KA, Won HH, Kim D. (2021) TransformerPRS: a deep learning-based polygenic risk model using bidirectional transformers derived from a language modeling model. ASHG’21: American Society of Human Genetics, Virtual, Oct 18-22, 2021.
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Mai H, Bao J, Thompson PM, Kim D, Shen L. (2021) Identifying genes associated with brain volumetric differences through tissue specific transcriptomic inference from GWAS summary data. ICIBM’21: Int. Conf. on Intelligent Biology and Medicine, Virtual Conference, August 8-10, 2021.
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Feng Y, Kim M, Yao X, Liu K, Long Q, Shen L, for the ADNI. (2021) Deep multiview learning to identify imaging-driven subtypes in mild cognitive impairment. ICIBM’21: Int. Conf. on Intelligent Biology and Medicine, Virtual Conference, August 8-10, 2021.
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Kim M, Wu R, Yao X, Saykin AJ, Moore JH, Shen L, for the ADNI. (2021) Identifying genetic markers enriched by brain imaging endophenotypes in Alzheimer's disease. ICIBM’21: Int. Conf. on Intelligent Biology and Medicine, Virtual Conference, August 8-10, 2021.
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Baik JY, Kim M, Bao J, Long Q, Shen L, for the ADNI. (2021) Identifying Alzheimer’s genes via brain transcriptome mapping. ICIBM’21: Int. Conf. on Intelligent Biology and Medicine, Virtual Conference, August 8-10, 2021.
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Lee B, Yao X, Shen L, for the ADNI. (2021) Integrative analysis of summary data from GWAS and eQTL studies implicates genes differentially expressed in Alzheimer’s disease. ICIBM’21: Int. Conf. on Intelligent Biology and Medicine, Virtual Conference, August 8-10, 2021.
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Kim M, Yao X, Saykin AJ, Moore JH, Long Q, Kim D, Shen L. (2021) Identifying imaging genetics biomarkers in Alzheimer’s disease via integrating graph convolutional neural network and canonical correlation analysis. AAIC'21: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Denver, USA and Online, July 26-30, 2021.
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Feng Y, Kim M, Liu K, Saykin AJ, Moore JH, Long Q, Shen L. (2021) Identifying Multimodal Imaging-Driven Subtypes in Mild Cognitive Impairment using Deep Multiview Learning. AAIC'21: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Denver, USA and Online, July 26-30, 2021.
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Lee BN, Wang J, Shen L. (2021) Identifying precision AD biomarkers with varying prognosis effects in genetics driven subpopulations. AAIC'21: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Denver, USA and Online, July 26-30, 2021.
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Jung SH, Nho K, Shen L, Kim D, Won HH. (2021) Novel polygenic risk score approach with transcriptome-based weighting for genetic risk prediction of late-onset Alzheimer’s disease. AAIC'21: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Denver, USA and Online, July 26-30, 2021.
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Zhang Y, Lee B, Shen L. (2021) Analysis of rate of change in quantitative traits for identifying biomarker-mediated genetic effects on MCI and AD. AAIC'21: Alzheimer's Association Int. Conf. on Alzheimer's Disease, (Developing Topics), Denver, USA and Online, July 26-30, 2021.
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Lee G, Nho K, Suh E, Kim M, Shen L, Sohn KA, Kim D. (2021) Prediction of MCI-to-AD progression via integration of genetic data and longitudinal biomarkers, imaging and clinical data. AIC'21: Alzheimer's Imaging Consortium, Denver, USA and Online, July 26-30, 2021.
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Abbas K, Wang M, Duong-Tran D, Liu M, Tipnis U, Shen L, Kaplan A, Harezlak J and Goni J. (2021) Tangent space projections of Functional Connectomes improve their phenotypic reliability as measured by their fingerprint gradient. NetNeuro’21: The Network Neuroscience Satellite to the Networks 2021 Conference, Virtual Conference, June 30 and July 1, 2021.
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Kim M, Wu R, Yao X, Saykin AJ, Moore JH, Shen L. (2021) Linking genetics to Alzheimer’s disease via human brain mapping. OHBM’21: Organization for Human Brain Mapping Ann Meeting, Virtual Conference, June 21-25, 2021.
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Bao J, Kim M, Yao X, Le T, Orzechowski P, Yan J, Saykin AJ, Moore JH, Shen L. (2021) Mining brain-wide gene expression data to identify imaging genomic modules via biclustering. OHBM’21: Organization for Human Brain Mapping Ann Meeting, Virtual Conference, June 21-25, 2021.
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Kim M, Qu J, Huang H, Shen L. (2021) Detecting imaging biomarkers for Alzheimer’s disease via interpretable graph convolutional network. OHBM’21: Organization for Human Brain Mapping Ann Meeting, Virtual Conference, June 21-25, 2021.
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Mai H, Bao J, Thompson P, Kim D, Shen L. (2021) Identifying tissue specific transcriptomic effects on brain volume measures from GWAS summary data. OHBM’21: Organization for Human Brain Mapping Ann Meeting, Virtual Conference, June 21-25, 2021.
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Lee BN, Wang J, Hall MA, Kim D, Stites SD, Shen L. (2021) Sex modifies predictive effects of imaging and CSF biomarkers on Alzheimer’s disease cognitive outcomes. DementiaDisparities'21: Promoting Diverse Perspectives: Addressing Health Disparities Related to Alzheimer’s and All Dementias, virtual conference, June 14-16, 2021.
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Shen L. (2021) Brain imaging genetics: integrated analysis and statistical machine learning. ENAR'21: ENAR 2021 Spring Meeting, Virtual Conference, March 14-17, 2021.
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Meng X, Li J, Zhang Q, Chen F, Bian C, Yao X, Yan J, Xu Z, Risacher SL, Saykin AJ, Liang H, Shen L, for the ADNI. (2020) Multivariate genome wide association and network analysis of subcortical imaging phenotypes in Alzheimer's disease. ICIBM’20: Int. Conf. on Intelligent Biology and Medicine, Virtual Conference, August 9-10, 2020.
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Li J, Bian C, Chen D, Meng X, Luo H, Liang H, Shen L, for the ADNI. (2020) Effect of APOE ε4 on multimodal brain connectomic traits: a persistent homology study. ICIBM’20: Int. Conf. on Intelligent Biology and Medicine, Virtual Conference, August 9-10, 2020.
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Lee B, Yao X, Shen L. (2020) Genome-wide association study of ADNI QT-PAD biomarkers identifies a novel locus on Chr 12. AAIC'20: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Virtual Conference, July 27-31, 2020.
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Yao X, Shen L, for the ADNI. (2020) Integrative analysis of summary data from GWAS and eQTL studies predicts tissue-specific gene targets for Alzheimer’s disease. AAIC'20: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Virtual Conference, July 27-31, 2020.
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Yu M, Nho K, Risacher SL, Chumin EJ, West JD, Tharp Matt, Zhu J, Wen Q, Eastman B, Shen L, Apostolova LG, Wu Y, Sporns O, Saykin AJ. (2020) Transcriptomic profiles underlying functional brain networks at different stages of Alzheimer’s disease. AAIC'20: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Virtual Conference, July 27-31, 2020.
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Kim M, Yao X, Park B, Yan J, Shen L. (2020) Imaging genetic strategies for predicting the quality of sleep using depression-specific biomarkers. OHBM’20: Organization for Human Brain Mapping Ann Meeting, Virtual Conference, June 26-30, 2020.
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Cong S, Yao X, Kim M, Xie L, Yan J, Shen L. (2020) Genome-wide brain-wide analysis of betweenness centrality: A structural connectome study. OHBM’20: Organization for Human Brain Mapping Ann Meeting, Virtual Conference, June 26-30, 2020.
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Eng Y, Yao X, Liu K, Risacher S, Saykin A, Long Q, Zhao Y, Shen L. (2020) Polygenic mediation analysis of amyloid imaging phenotypes in Alzheimer's disease. OHBM’20: Organization for Human Brain Mapping Ann Meeting, Virtual Conference, June 26-30, 2020.
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Sun Q, Huang Z, Kim M, Hara A, Maupome G, Shen L. (2020) Identifying hard-tissue conditions from dental images using convolutional neural network. ISBI’20: IEEE International Symposium on Biomedical Imaging, Iowa City, Iowa, April 3 - 7, 2020.
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Maupomé G, Hara AT, Huang Z, Shen L. (2019) Machine-learning identification of dental hard-tissue conditions through fully convolutional neural networks. APHA’19: American Public Health Association Annual Meeting and Expo. Philadelphia, USA, November 2-6, 2019.
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Min EJ, Shen L, Long Q. (2019) Sparse tensor co-inertia analysis with application to integrative analysis of genomic data and imaging data. JSM’19: Joint Statistical Meetings. Denver, USA, July 27 – August 1, 2019.
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Inlow M, Cong S, Shen L. (2019) A new adaptive signal detection method for neuroimage analysis. JSM’19: Joint Statistical Meetings. Denver, USA, July 27 – August 1, 2019.
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Cong S, Yao X, Risacher SL, Nho K, Saykin AJ, Shen L, ADNI. (2019) GWAS of hippocampal subfield and neighboring cortical structure volumes identifies an ERC1 locus using ADNI high-resolution MRI data. AAIC'19: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Los Angeles, USA, July 14-18, 2019.
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Yao X, Tsang T, Qing Sun, Quinney S, Zhang P, Ning X, Li L, Shen L. (2019) Mining and visualizing high-order directional drug interaction effects using the FAERS database. ICIBM’19: Int. Conf. on Intelligent Biology and Medicine, Columbus, OH, USA, June 9-11, 2019.
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Chung MK, Huang SG, Gritsenko A, Shen L, Lee H (2019) Statistical inference on the number of cycles in structural brain networks. OHBM’19: Organization for Human Brain Mapping Ann Meeting, Rome, Italy, June 9-13, 2019.
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Tipnis U, Amico E, Kaplan A, Abbas K, Svaldi DO, Xie L, Yan J, Wang M, Dzemidzic M, Kareken D, Shen L, Goni J. (2019) Twin fingerprints: optimal mapping of heritable and environmental traits in the human connectome. NN’19: Network Neuroscience, Burlington, VT, May 28, 2019.
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Yao X, Yan J, Saykin AJ, Shen L, and for the ADNI. (2018) Genetic findings using ADNI multimodal quantitative phenotypes: A 2017 update. AAIC'18: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Chicago, USA, July 22-26, 2018.
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Tipnis U, Amico E, Xie L, Yan J, Wang M, Dzemidzic M, Kareken D, Shen L, Goni J. (2018) Twin fingerprinting: Optimal mapping of heritable traits in the human connectome. CNS’18: The 27-th Annual Computational Neuroscience Meeting, Seattle, USA, July 13-18, 2018.
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Yao X, Risacher SL, Nho K, Saykin AJ, Huang H, Wang Z, Shen L. (2018) Genetic analysis of cerebral blood flow imaging phenotypes in Alzheimer’s disease. PSB’18: Pac Symp Biocomput., Big Island of Hawaii, January 3-7, 2018.
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Shen L, Kennedy D, Haselgrove C, Paulson A, Preuss N, Buccigrossi R, Travers M, Crowley A, and The NITRC Team. (2018) The neuroimaging informatics tools and resources collaboratory (NITRC) and its imaging genomics domain. PSB’18: Pac Symp Biocomput., Big Island of Hawaii, January 3-7, 2018.
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Yao X, Yan J, Liu K, Risacher S, Nho K, Saykin A, Shen L. (2017) Discovering high level genetic associations with imaging phenotypes using tissue-specific functional interaction networks. BIN’17: Brain Informatics 2017 Special Session on Brain Informatics in Neurogenetics, Beijing, China, November 18, 2017.
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Liu W, Li J, Liang H, Shen L. (2017) An online visual exploratory system for mining large-scale imaging genomic data. BIN’17: Brain Informatics 2017 Special Session on Brain Informatics in Neurogenetics, Beijing, China, November 18, 2017.
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Chen F, Li J, Liang H, Shen L. (2017) Genome-wide network-based analysis of AV-45 PET measures in the ADNI cohort. BIN’17: Brain Informatics 2017 Special Session on Brain Informatics in Neurogenetics, Beijing, China, November 18, 2017.
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Raja VV, Risacher SL, Nho K, Shen L, Saykin AJ, Yan J. (2017) Investigation of genetic influences on atrophy rate during the MCI disease stage using a bootstrap-enhanced sparse association model. AAIC'17: Alzheimer's Association Int. Conf. on Alzheimer's Disease, London, UK, July 16-19, 2017.
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Saykin AJ, Nho K, Yan J, Nudelman KNH, Risacher SL, Kim S, Apostolova LG, Shen L, Kaddurah-Daouk RF. (2017) Integrating multi-modality imaging and multi-layer -omics to advance the systems biology of Alzheimer’s disease. AAIC'17: Alzheimer's Association Int. Conf. on Alzheimer's Disease, London, UK, July 16-19, 2017.
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Yao X, Yan J, Nho K, Risacher SL, Borner K, Saykin AJ, Shen L, and for the ADNI. (2017) Genetic findings using ADNI multimodal quantitative phenotypes: A 2016 update. AAIC'17: Alzheimer's Association Int. Conf. on Alzheimer's Disease, London, UK, July 16-19, 2017.
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Yan J, Liu K, Li H, Amico E, Risacher SL, Wu Y, Fang S, Sporns O, Saykin AJ, Goni J, Shen L, and for the ADNI. (2017) Joint exploration and mining of memory-relevant brain anatomic and connectomic patterns via a three-way association model. NN’17: NetSci 2017 Satellite on Network Neuroscience, Indianapolis, IN, June 20, 2017. [Platform talk]
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Yan J, Liu K, Risacher SL, Nho K, Saykin AJ, Shen L, and for the ADNI. (2017) Graph embedded sparse association model for joint identification of discriminative imaging proteomic markers and their associations. NN’17: NetSci 2017 Satellite on Network Neuroscience, Indianapolis, IN, June 20, 2017.
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Yao X, Yan J, Nho K, Risacher S, Greene C, Moore J, Saykin A, Shen L. (2017) Identifying phenotype-relevant modules from a tissue-specific biological network: Application to an amygdala imaging genetics study. NetSci’17: Int. School and Conf. on Network Science, Indianapolis, IN, June 21-23, 2017. [Platform talk]
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Liu K, Li H, Fang S, Amico E, West J, Yan J, Wu Y, Sporns O, Saykin A, Goni J, Shen L. (2017) Simultaneous community detection in structural brain networks across multiple subjects. NetSci’17: Int. School and Conf. on Network Science, Indianapolis, IN, June 21-23, 2017.
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Ning X, Li L, Shen L. (2017) Pattern discovery from directional high-order drug-drug interaction relations. NetSci’17: Int. School and Conf. on Network Science, Indianapolis, IN, June 21-23, 2017.
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Chasioti D, Yao X, Zhang P, Quinney S, Ning X, Li L, Shen L. (2017) Mining and visualizing the network of directional drug interaction effects. NetSci’17: Int. School and Conf. on Network Science, Indianapolis, IN, June 21-23, 2017.
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Yao X, Yan J, Risacher S, Greene C, Moore J, Saykin A, Shen L. (2017) Network-based genome wide study of hippocampal imaging phenotype in Alzheimer’s disease to identify functional interaction modules. IIGC’17: 13th International Imaging Genetics Conference, Irvine, CA, Feb 13-14, 2017. (Best Poster Award, 1st Place)
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The NITRC Team. (2017) Imaging Genomics at NITRC. IIGC’17: 13th International Imaging Genetics Conference, Irvine, CA, Feb 13-14, 2017.
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Chasioti D, Yao X, Zhang P, Ning X, Li L, Shen L. (2017) Mining directional drug interaction effects on myopathy using the FAERS database. PSB’17: Pac Symp Biocomput., poster #71, Big Island of Hawaii, January 3-7, 2017
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Kim S, Nho K, Shen L, Franklin E, Morris JC, Cairns N, Saykin AJ, and for the ADNI. (2016) Influence of Parkinson’s disease candidate genes on Lewy body pathology in autopsy-confirmed Alzheimer's disease cases. AAIC'16: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Toronto, Canada, July 24-28, 2016.
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Nho K, Kim S, Risacher SL, Shen L, Thompson PM, Gunn-Moore F, Saykin AJ, and for the ADNI. (2016) Whole brain surfaced-based analysis identified brain atrophy associated with SNPs in FRMD6 linked to Alzheimer's disease. AAIC'16: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Toronto, Canada, July 24-28, 2016.
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Yan J, Risacher SL, Shen L, Saykin AJ, and for the ADNI. (2016) Identification of discriminative brain imaging and genomic associations: An Alzheimer’s disease study. AAIC'16: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Toronto, Canada, July 24-28, 2016. [Platform talk]
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Kim S, Toledo J, Nho K, Risacher SL, Shen L, Thompson JW, Williams LSJ, Tenenbaum J, Han X, Baillie R, Thambisetty M, Casanova R, Varma S, Legido-Quigley C, Mahmoudiandehkordi S, Motsinger-Reif A, Zhu H, Kastenmueller G, Suhre K, Dallmann G, Klavins K, Koal T, Moseley MA, Trojanowski JQ, Shaw LM, Weiner MW, Doraiswamy PM, Kaddurah-Daouk R, Saykin AJ, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI) and the Alzheimer Disease Metabolomics Consortium. (2016) Genetic influence on levels of targeted metabolites associated with Alzheimer’s disease. AAIC'16: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Toronto, Canada, July 24-28, 2016. [Platform talk]
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Cong S, Risacher SL, West JD, Wu Y, Apostolova L, Tallman E, Rizkalla M, Salama P, Saykin AJ, Shen L. (2016) Volumetric comparison of automatically segmented hippocampal subfields from 4-min accelerated versus 8-min t2-weighted 3T MRI scans. AAIC'16: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Toronto, Canada, July 24-28, 2016.
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Yao X, Yan J, Ginda M, Borner K, Kim S, Nho K, Risacher SL, Foroud TM, Potkin SG, Thompson PM, Moore JH, Weiner MW, Saykin AJ, Shen L, and for the ADNI. (2016) The growth and impact of ADNI genetics publications as measured by science mapping. AAIC'16: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Toronto, Canada, July 24-28, 2016.
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Liang H, Zhang Q, Meng X, Chen F, Yao X, Yan J, Kim S, Wang L, Feng W, Saykin AJ, Li J, Shen L, and for the ADNI. (2016) Genome-wide association and network analysis of the CSF biomarker Tau in the ADNI cohort. IIGC’16: 12th International Imaging Genetics Conference, Irvine, CA, Jan 18-19, 2016.
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Yan J, Du L, Risacher SL, Shen L, Saykin AJ, and for the ADNI. (2016) Identification of diagnosis related imaging genomics associations through outcome-guided sparse CCA: An Alzheimer’s disease study. IIGC’16: 12th International Imaging Genetics Conference, Irvine, CA, Jan 18-19, 2016.
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The NITRC Team. (2016) A NITRC Update on Imaging Genomics. IIGC’16: 12th International Imaging Genetics Conference, Irvine, CA, Jan 18-19, 2016.
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Ramanan VK, Risacher SL, Nho K, Kim S, Shen L, Foroud TM, Aisen PS, Petersen RC, Toga AW, Green RC, Jagust WJ, Weiner MW, Saykin AJ, and for the ADNI. (2015) GWAS of longitudinal amyloid PET identifies IL1RAP as a new potential Alzheimer's disease target. AAIC'15: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Washington DC, USA, July 18-23, 2015.
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Risacher SL, Shen L, Goñi J, Contreras JA, West JD, Sujuan Gao, Paul M. Thompson, Aisen PS, Jack Jr. CR, Petersen RC, Weiner MW, Saykin AJ, and for the ADNI. (2015) Association of eye disease with increased diffusivity in the sagittal stratum. AAIC'15: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Washington DC, USA, July 18-23, 2015.
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Risacher SL, Shen L, West JD, Zheng Y, Kim S, Nho K, Crane PK, Aisen PS, Petersen RC, Jack Jr. CR, Weiner MW, Saykin AJ, and for the ADNI. (2015) Effect of hypertension and antihypertensive medication on executive function, brain atrophy, and white matter hyperintensities. AAIC'15: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Washington DC, USA, July 18-23, 2015.
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Risacher SL, Kim S, Nho K, Shen L, Crane PK, Aisen PS, Petersen RC, Jack Jr. CR, Weiner MW, Saykin AJ, and for the ADNI. (2015) Anticholinergic medication use in older adults is associated with memory and hippocampal volume. AAIC'15: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Washington DC, USA, July 18-23, 2015.
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Nho K, Kim S, Risacher SL, Ramanan VK, Shen L, Foroud TM, Gibbons LE, Crane PK, Weiner MW, Green RC, Toga AW, Saykin AJ, and for the ADNI. (2015) Genome-wide rare variant analysis identifies candidate genes significantly associated with composite scores for memory. AAIC'15: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Washington DC, USA, July 18-23, 2015.
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Kim S, Nho K, Risacher SL, Shen L, Shaw LM, Trojanowski JQ, Weiner MW, Saykin AJ, and for the ADNI. (2015) MAPRE2 as a novel Alzheimer's disease target gene from GWAS of CSF amyloid beta 1-42, tau and hyper-phosphorylated tau in the ADNI cohort. AAIC'15: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Washington DC, USA, July 18-23, 2015.
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Kaddurah-Daouk R, Kling MA, Shaw LM, Arnold SE, Trojanowski JQ, Toledo JB, Saykin AJ, Kim S, Shen L, Han X, Goodenowe DB, Smith T, Senanayake V, Doraiswamy PM. (2015) The Alzheimer’s metabolome: Identification of novel markers and treatment targets. AAIC'15: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Washington DC, USA, July 18-23, 2015.
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Yan J, Kim S, Nho K, Yao X, Risacher SL, Moore JH, Saykin AJ, Shen L, and for the ADNI. (2015) Identification of common genetic biomarkers across correlated episodic memory performances. AAIC'15: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Washington DC, USA, July 18-23, 2015.
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Cong W, Meng X, Liang H, Zhang Q, Chen F, Feng W, Yan J, Kim S, Saykin AJ, Li J, Shen L, and for the ADNI. (2015) Genome-wide network-based pathway analysis of CSF biomarker t-tau in the ADNI cohort. AAIC'15: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Washington DC, USA, July 18-23, 2015.
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Yao X, Yan J, Kim S, Nho K, Risacher SL, Borner K, Foroud TM, Thompson PM, Potkin SG, Sarwar N, Munsie L, Soares H, Green RC, Toga AW, Weiner MW, Saykin AJ, Shen L, and for the ADNI. (2015) Genetic findings using ADNI multimodal quantitative phenotypes: A 2014 update. AAIC'15: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Washington DC, USA, July 18-23, 2015.
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Zhang Q, Li J, Chen F, Yan J, Kim S, Wang L, Feng W, Saykin AJ, Liang H, Shen L, and for the ADNI. (2015) Genome-wide interaction study of amyloid imaging phenotypes in the ADNI cohort. IIGC’15: 11th International Imaging Genetics Conference, Irvine, CA, Jan 17-18, 2015. (Best Poster Award, 1st Place)
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Yao X, Kim S, Yan J, Risacher SL, Inlow M, Moore JH, Saykin AJ, Shen L, and for the ADNI. (2015) Joint analysis of multiple amyloid imaging phenotypes in a genome wide association study of the ADNI cohort. IIGC’15: 11th International Imaging Genetics Conference, Irvine, CA, Jan 17-18, 2015.
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The NITRC Team. (2015) The neuroimaging informatics tools and resources clearinghouse (NITRC). IIGC’15: 11th International Imaging Genetics Conference, Irvine, CA, Jan 17-18, 2015.
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Nho K, Kim S, Risacher SL, Shen L, Foroud T, Aisen PS, Petersen RC, Jack CR, Shaw LM, Trojanowski JQ, Weiner MW, Green RC, Toga AW, Saykin AJ, for the ADNI (2014) Influence of Rare PSEN1 Variants on Quantitative Structural Imaging and CSF Phenotypes in Late Onset Alzheimer’s Disease. AAIC'14: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Copenhagen, Denmark, July 12-17, 2014.
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Nho K, Kim S, Risacher SL, Shen L, Foroud T, Aisen PS, Petersen RC, Jack CR, Weiner MW, Green RC, Toga AW, Saykin AJ, for the ADNI (2014) Rare variant in PLD3 is associated with Alzheimer’s pattern of neurodegenerative changes. AAIC'14: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Copenhagen, Denmark, July 12-17, 2014.
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Nho K, Kim S, Risacher SL, Shen L, Foroud T, Shaw LM, Trojanowski JQ, Aisen PS, Petersen RC, Jack CR, Weiner MW, Green RC, Toga AW, Saykin AJ, for the ADNI (2014) Association Analysis of Rare Variants near the APOE region with cerebrospinal fluid (CSF) biomarkers of Alzheimer’s Disease. AAIC'14: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Copenhagen, Denmark, July 12-17, 2014.
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Risacher SL, Kim S, KwangsiNho K, Shen L, West JD, Wang Y, Petersen R, Jack CR, Aisen PS, Jagust WJ, Koeppe RM, John Q. Trojanowski9, Leslie M. Shaw9, Michael W. Weiner10,11, Saykin Aj, for the ADNI (2014) Increased amyloid deposition in older adults at risk for progression to Alzheimer’s disease due to genetic background and/or the presence of significant memory concerns. AAIC'14: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Copenhagen, Denmark, July 12-17, 2014.
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Risacher SL, Kim S, Nho K, Shen L, West JD, Petersen R, Jack CR, Aisen PS, Jagust WJ, Koeppe RM, Weiner MW, Saykin Aj, for the ADNI (2014) Two-Year Longitudinal Change in Amyloid Deposition, Glucose Metabolism, Hippocampal Atrophy and Cognition in ADNI-2 Participants. AAIC'14: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Copenhagen, Denmark, July 12-17, 2014.
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Kim S, Risacher SL, Nho K, Shen L, Shaw LM, Trojanowski JQ, Weiner MW, Saykin AJ, for the ADNI (2014) Association of plasma leptin/adiponectin ratio in men with CSF biomarkers in the ADNI-1 cohort. AAIC'14: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Copenhagen, Denmark, July 12-17, 2014.
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Kim S, Nho K, Risacher SL, Rajagopalan P, Shen L, Shaw LM, Trojanowski JQ, Kling MA, Han X, Goodenowe D, Rotroff D, Motsinger-Reif AA, Doraiswamy PM, Kaddurah-Daouk R, Green RC, Toga AW, Weiner MW, Saykin AJ, Alzheimer’s Metabolomics Network, for the ADNI (2014) Whole gene-based association of baseline plasma homocysteine in the ADNI-1 cohort. AAIC'14: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Copenhagen, Denmark, July 12-17, 2014.
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Yan J, Kim S, Nho K, Risacher SL, Moore JH, Saykin AJ, Shen L, for the Alzheimer's Disease Neuroimaging Initiative (2014) Effects of newly identified top AD genes on memory performance: SNP, Gene and Epistasis Analyses in ADNI. AAIC'14: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Copenhagen, Denmark, July 12-17, 2014.
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Yan J, Kim S, Nho K, Risacher SL, Moore JH, Saykin AJ, Shen L, for the Alzheimer's Disease Neuroimaging Initiative (2014) Genome-wide protein interaction guided epistatic analysis on memory performance: An ADNI study. AAIC'14: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Copenhagen, Denmark, July 12-17, 2014.
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Yao X, Chen R, Kim S, Yan J, Du L, Nho K, Foroud TM, Moore JH, Weiner MW, Saykin AJ, Shen L, for the Alzheimer's Disease Neuroimaging Initiative (2014) Genetic Findings using ADNI Multimodal Quantitative Phenotypes: A Review of Papers Published in 2013. AAIC'14: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Copenhagen, Denmark, July 12-17, 2014.
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Chen R, Kim S, Huang H, Shen L, Wang J. (2014) Genome-wide analysis of newly developed quantitative phenotypes of astigmatism. ARVO’14: Association for Research in Vision and Ophthalmology, Orlando, FL, May 4-8, 2014.
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Cong S, Rizkalla M, Yan J, West J, Kim S, Risacher S, Saykin A, Shen L, for the ADNI (2014) Reproducibility of hippocampal subfield segmentation using FreeSurfer and FIRST. ISBI’14: IEEE Int. Sym. on Biomedical Imaging, Beijing, China, 28 April - 2 May, 2014.
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The NITRC Team (2014) The neuroimaging informatics tools and resources clearinghouse (NITRC). IIGC’14: 10th International Imaging Genetics Conference, Irvine, CA, Jan 20-21, 2014.
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Wang J, Ren X, Shen L, Yanni SE, Leffler JN, Birch EE. Progression of anisometropia in children with regressed ROP (2013) SNEC/AAPOS'13: The joint meeting of Singapore National Eye Center (SNEC) & AAPOS, Singapore, July 14-16, 2013
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Risacher SL, Kim S, Yoder KK, Shen L, West JD, McDonald BC, Wang Y, Nho K, Tallman E, Hutchins GD, Fletcher JW, Ghetti B, Gao S, Farlow MR, Saykin AJ (2013) Relationship of microglial activation measured by [11C]PBR28 PET, atrophy on MRI, and plasma biomarkers in individuals with and at-risk for Alzheimer’s disease. AAIC'13: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Boston, MA, July 13-18, 2013.
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Saykin AJ, Risacher SL, McDonald BC, West JD, Tallman EF, Flashman LA, Wishart HA, Rabin LA, Paré N, O’Neill DP, Wang Y, Shen L, Santulli RB, Farlow MR (2013) Two-year outcome in older adults with subjective cognitive decline: Relation to baseline cognition, self and informant complaints, genetics, and imaging. AAIC'13: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Boston, MA, July 13-18, 2013.
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Risacher SL, Kim S, Klaunig JE, Shen L, McDonald BC, Farlow MR, Ghetti B, Gao S, Wang Z, Zhou S, Saykin AJ (2013) DNA damage in peripheral blood cells is associated with Alzheimer’s-related plasma proteins in individuals at risk for progression to Alzheimer’s disease. AAIC'13: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Boston, MA, July 13-18, 2013.
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Saykin AJ, Risacher SL, McDonald BC, West JD, Tallman EF, Flashman LA, Wishart HA, Rabin LA, Pare N, O'Neill DP, Wang Y, Shen L, Santulli RB, Farlow MR (2013) Two year outcome in older adults with cognitive complaints: Relation to baseline cognition, self and informant ratings, genetics and imaging. AAIC'13: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Boston, MA, July 13-18, 2013.
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Wang Y, West JD, Shen L, Risacher SL, Sporns O, McDonald BC, Tallman E, Ghetti B, Gao S, Farlow MR, O'Neill D, Xiao H, Saykin AJ (2013) Altered connectome mapping in prodromal Alzheimer's disease and older adults with cognitive complaints. AAIC'13: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Boston, MA, July 13-18, 2013.
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Ramanan VK, KwangsiNho K, Shen L, Risacher SL, Kim S, Foroud TM, Bennett DA, and Saykin AJ, for the Alzheimer’s Disease Neuroimaging Initiative (2013) Predictors of memory performance in a large stratified random population sample of older Americans: clinical, demographic, lifestyle, and genetic factors. AAIC'13: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Boston, MA, July 13-18, 2013. [Platform talk]
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Nho K, Corneveaux JJ, Kim S, Lin H, Risacher SL, Shen L, Swaminathan S, Ramanan VK, Liu Y, Foroud T, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, Green RC, Jack CR, Weiner MW, Baldwin CT, Lunetta K, Farrer LA, for the Multi-Institutional Research on Alzheimer Genetic Epidemiology (MIRAGE) Study, Furney SJ, Lovestone S, Simmons A, Mecocci P, Vellas B, Tsolaki M, Kloszewska I, Soininen H, for the AddNeuroMed Consortium, McDonald BC, Farlow MR Ghetti B, for the Indiana Memory and Aging Study, Huentelman MJ, Saykin AJ, for the Alzheimer's Disease Neuroimaging Initiative (2013) Protective variant for rate of hippocampal volume loss identified by whole exome sequencing in APOE e3/e3 males with MCI. AAIC'13: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Boston, MA, July 13-18, 2013. [Platform talk]
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Nho K, Swaminathan S, Kim S, Risacher SL, Ramanan VK, Shen L, Mackin RS, Alsen PS, Petersen RC, Weiner MW, McDonald BC, Farlow MR, Ghetti B, Gao S, for the Indiana Memory and Aging Study, Saykin AJ, for the Alzheimer's Disease Neuroimaging Initiative (2013) Genome-Wide Analysis of Genetic Variants Associated with Depressive Symptoms in Older Adults. AAIC'13: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Boston, MA, July 13-18, 2013.
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Nho K, Kim S, Risacher SL, Shen L, Sherva R, Green RC, Weiner MW, Saykin AJ, for the Alzheimer's Disease Neuroimaging Initiative (2013) Imaging Genetics of SPON1 Gene Variant rs11023139 in Alzheimer’s Disease. AAIC'13: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Boston, MA, July 13-18, 2013.
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Kim S, Nho K, Risacher SL, Swaminathan S, Yoder KK, Shen L, West JD, McDonald BC, Tallman EF, Hutchins GD, Fletcher JW, Farlow MR, Ghetti B, Saykin AJ (2013) Influence of PARP1 gene on [11C]PBR28 PET Brain Uptake. AAIC'13: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Boston, MA, July 13-18, 2013.
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Kim S, Nho K, Shen L, Kling MA, Han X, Zhu H, Sullivan PM, Arnold SE, Risacher SL, Ramanan VK, Doraiswamy PM, Trojanowski JQ, Kaddurah-Daouk R, Saykin AJ, for Alzheimer’s Disease Neuroimaging Initiative (2013) Targeted lipidomic pathway-guided genetic association with Alzheimer’s disease-relevant endophenotypes. AAIC'13: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Boston, MA, July 13-18, 2013. [Platform talk]
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Shen L, Thompson PM, Potkin SG, Stone DJ, Kim S, Nho K, Ramanan VJ, Green RC, Foroud TM, Farrer LA, Moore JH, Bertram L, Weiner MW, Saykin AJ, for the ADNI (2013) A review of published genetic studies using ADNI multimodality quantitative phenotypes: MRI, PET, Fluid biomarkers, cognition, and clinical status. AAIC'13: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Boston, MA, July 13-18, 2013.
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Shen L, Kennedy DN, Preuss N, for the NITRC Team (2013) The three NITRC's: Software, data and cloud computing for brain science and dementia research. AAIC'13: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Boston, MA, July 13-18, 2013.
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Yan J, Kim S, Nho K, Chen R, Risacher SL, Moore JH, Saykin AJ, Shen L, for the ADNI (2013) Hippocampal transcriptome-guided gene-gene interaction of memory phenotype in MCI and AD. AAIC'13: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Boston, MA, July 13-18, 2013. [Platform talk at The Alzheimer's Imaging Consortium (AIC) pre-conference]
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Wan J, Zhang Z, Fang S, Risacher SL, Saykin AJ, Shen L, for the ADNI (2013) Sparse Bayesian learning for identifying the neuroanatomical basis of cognitive impairment in AD. AAIC'13: Alzheimer's Association Int. Conf. on Alzheimer's Disease, Boston, MA, July 13-18, 2013.
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Yan J, Risacher SL, Kim S, Huang H, Saykin AJ, Shen L, for the ADNI (2013) Network-guided sparse learning for improved MRI-based prediction of cognitive performance. OHBM’13: Organization for Human Brain Mapping Ann Meeting, June 16-20, 2013, Seattle, WA.
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Nho K, Corneveaux J, Kim S, Lin H, Risacher SL, Shen L, Liu Y, Foroud T, Inlow M, Siniard A, Reiman R, Clifford J, Weiner M, Huentelman M, Saykin AJ (2013) Integration of bioinformatics and imaging informatics for identifying variants from whole-exome sequencing. AMIA-JS'13: AMIA Joint Summits on Translational Science, San Francisco, CA, March 18-22, 2013. (Silver Medallion poster)
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The NITRC Team (2013) The neuroimaging informatics tools and resources clearinghouse (NITRC). IIGC’13: 10th International Imaging Genetics Conference, Irvine, CA, Jan 20-21, 2013.
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Ramanan VK, Shen L, West JD, Kim S, Risacher SL, Nho K, Wang Y, Wan J, Foroud TM, Farrer LA, Saykin AJ, for the ADNI (2012) Genome-wide pathway analysis in multiple cohorts implicates histone genes and inflammation in hippocampal atrophy. ASHB’12: The 62nd Annual Meeting of the American Society of Human Genetics, San Francisco, CA, November 6-10, 2012.
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Li T, Yan J, Kim S, Swaminathan S, Risacher SL, Shaw LM, Trojanowski JQ, Aisen PS, Petersen RC, Weiner MW, Saykin AJ, Shen L, for the ADNI (2012) Classification of MCI and AD from CSF biomarkers: An ADNI study of Abeta, tau and p-tau versus 83 proteomic analytes. AAIC’12: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, Vancouver, Canada, July 14-19, 2012. [Platform talk]
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Yan J, Li T, Risacher SL, McDonald BC, WuDunn D, Farlow MR, Pepin SM, Flashman LA, Wishart HA, Santulli RB, Saykin AJ, Shen L (2012) Visual contrast sensitivity as a novel biomarker: Discriminative analysis using elastic net to classify AD, MCI and older adults with cognitive complaints. AAIC’12: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, Vancouver, Canada, July 14-19, 2012.
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Saykin AJ, Shen L, Risacher SL, Swaminathan S, Kim S, Nho K, Thompson PM, Potkin SG, Farrer LA, Lovestone S, Jack CR, Jagust WJ, Weiner MW, the ADNI (2012) Structural, functional and molecular imaging as intermediate phenotypes for studies of candidate genes, pathways and GWAS in Alzheimer’s disease. AAIC’12: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, Vancouver, Canada, July 14-19, 2012. [Platform talk]
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Melville S, Buros J, Parrado A, Vardarajan B, Shen L, Risacher SL, Kim S, Jun G, DeCarli C, Lunetta KL, Baldwin CT, Saykin AJ, Farrer LA (2012) Genome-wide association study of Alzheimer-related brain MRI traits identifies several loci influencing degeneration of the hippocampus. AAIC’12: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, Vancouver, Canada, July 14-19, 2012. [Platform talk]
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Risacher SL, Kim S, Shen L, Nho K, Foroud T, Petersen RC, Aisen PS, Jack CR, Koeppe RA, Jagust WJ, Weiner MW, Saykin AJ, ADNI (2012) The role of APOE genotype in early mild cognitive impairment (E-MCI): Preliminary results from ADNI-2. AAIC’12: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, Vancouver, Canada, July 14-19, 2012. [Platform talk]
Risacher SL, Wang Y, West JD, MaGee TR, WuDunn D, Shen L, McDonald BC, Farlow MR, O'Neill DP, -
Risacher SL, Wang Y, West JD, MaGee TR, WuDunn D, Shen L, McDonald BC, Farlow MR, O'Neill DP, Saykin AJ (2012) Visual contrast sensitivity in MCI and older adults with cognitive complaints is associated with altered resting connectivity in the visual network. AAIC’12: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, Vancouver, Canada, July 14-19, 2012.
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Ramanan VK, Kim S, Holohan KN, Shen L, Nho K, Risacher SL, Foroud TM, Mukherjee S, Crane PK, Aisen PS, Petersen RC, Weiner MW, Saykin AJ, for the ADNI (2012) Common gene networks underlying memory impairment: a comparison of pathway analysis methods in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort. AAIC’12: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, Vancouver, Canada, July 14-19, 2012.
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Ramanan VK, Shen L, Risacher SL, Kim S, Boddu M, West JD, Wan J, Wang Y, Crane PK, Jack CR, Weiner MW, Saykin AJ, for the ADNI (2012) Hippocampal Subfield Atrophy in the Alzheimer's Disease Neuroimaging Initiative (ADNI) Cohort: Relationships to Diagnosis and Memory Impairment. AAIC’12: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, Vancouver, Canada, July 14-19, 2012.
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Wang Y, West JD, Magee TR, McDonald BC, Risacher SL, Shen L, Ramanan V, O'Neill DP, Farlow MR, Ghetti B, Saykin AJ (2012) Hippocampal subfield atrophy on 3T MRI in prodromal Alzheimer's disease and older adults with cognitive complaints. AAIC’12: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, Vancouver, Canada, July 14-19, 2012.
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Swaminathan S, Huentelman MJ, Corneveaux JJ, Myers AJ, Faber KM, Foroud T, Mayeux R, Shen L, Kim S, Hardy J, Reiman EM, Saykin AJ, for the ADNI and the NIA-LOAD/NCRAD Family Study Group (2012) Replication and meta-analysis of the CHRFAM7A copy number variant in a cohort of clinically characterized and neuropathologically verified individuals. AAIC’12: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, Vancouver, Canada, July 14-19, 2012.
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Kim S, Swaminathan S, Nho K, Risacher SL, Shen L, Foroud T, Shaw LM, Trojanowski JQ, Soares H, Weiner MW, Saykin AJ, for the ADNI (2012) Relationship between CSF and plasma proteomic data in the ADNI-1 cohort. AAIC’12: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, Vancouver, Canada, July 14-19, 2012.
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Kim S, Swaminathan S, Nho K, Risacher SL, Shen L, Foroud T, Shaw LM, Trojanowski JQ, Weiner MW, Saykin AJ, for the ADNI (2012) Pairwise gene-protein association analysis on CSF proteomics in the ADNI-1 cohort. AAIC’12: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, Vancouver, Canada, July 14-19, 2012.
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Shen L, Ai H, Liang Y, Anthony CB, Goodlett C, Ward R, Zhou FC, the CIFASD Consortium (2012) Effect of fetal alcohol exposure on craniofacial bone development in c57bl/6j mouse models: A dose and timing study. RSA’12: 35th Annual Research Society on Alcoholism Scientific Meeting, June 23-27, 2012, San Francisco, CA.
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Li T, Yan J, Wang H, Nie F, Huang H, Kim S, Risacher SL, Saykin AJ, Shen L (2012) Joint estimation of AD status and cognitive performance using VBM summary statistics. OHBM’12: Organization for Human Brain Mapping Ann Meeting, June 10-14, 2012, Beijing, China.
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Wan J, Ramanan V, Kim S, West JD, Boddu M, Risacher SL, Fang S, Saykin AJ, Shen L (2012) Classification of AD and MCI using hippocampal subfields: an ADNI study. OHBM’12: Organization for Human Brain Mapping Ann Meeting, June 10-14, 2012, Beijing, China.
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Yan J, Li T, Huang H, Risacher SL, West JD, Kim S, Saykin AJ, Shen L (2012) Clustering voxel-based gray matter maps for improved discrimination: An amygdala study in AD. OHBM’12: Organization for Human Brain Mapping Ann Meeting, June 10-14, 2012, Beijing, China.
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Luo D, Wang Y, Huang H, Sheng J, Cheng H, Saykin AJ, Shen L (2012) Detecting common connectivity modules from complex brain networks. OHBM’12: Organization for Human Brain Mapping Ann Meeting, June 10-14, 2012, Beijing, China.
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Wang Y, Shen L, Guo Y, Boddu M, West JD, Kim S, Hummer T, Kronenberger WG, Mathews VP, Saykin AJ (2012) Scan-rescan reliability of automated segmentation of cerebral cortex at multiple scales. OHBM’12: Organization for Human Brain Mapping Ann Meeting, June 10-14, 2012, Beijing, China.
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Swaminathan S, Shen L, Kim S, Inlow M, West JD, Foroud T, Faber KM, Mayeux R, Saykin AJ, The NIA-LOAD/NCRAD Family Study Group (2011) Analysis of copy number variation in Alzheimer's disease: the NIA-LOAD/NCRAD Family Study. ICHG’11: 12th Int Congress of Human Genetics, Montreal, Canada, October 11-15, 2011.
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Risacher SL, Shen L, West JD, Flashman LA, Wishart HA, Rabin LA, Paré N, Englert JJ, Schwartz ES, Kim S, McDonald BC, Curtain JR, Pixley HS, Santulli RB, Saykin AJ (2011) Longitudinal Structural MRI Changes in Alzheimer's Disease, Mild Cognitive Impairment, Older Adults with Cognitive Complaints: Relationship to Conversion Status. AAIC’11: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, July 16-21, 2011, Paris, France.
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Kim S, Swaminathan S, Inlow M, Risacher SL, Shen L, Foroud T, Shaw LM, Trojanowski JQ, Soares H, Weiner MW, Saykin AJ, ADNI (2011) Influence of genetic variation on plasma proteomics in AD, MCI and controls: Pairwise gene-protein analysis in the ADNI-1 cohort. AAIC’11: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, July 16-21, 2011, Paris, France.
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Swaminathan S, Risacher SL, Yoder KK, West JD, Shen L, Kim S, Inlow M, Foroud T, Jagust WJ, Koeppe RA, Mathis CA, Shaw LM, Trojanowski JQ, Soares H, Aisen PS, Petersen RC, Weiner MW, Saykin AJ, ADNI (2011) APOE E4 status modulates the association of plasma and cortical AB: Relation of plasma AB and [11C]PiB PET in the ADNI cohort. AAIC’11: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, July 16-21, 2011, Paris, France.
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Hemond CC, Nho K, Shen L, Risacher SL, Kim S, Saykin AJ, Greicius MD, ADNI (2011) Reelin interacts with ApoE to exacerbate Alzheimer's disease endophenotypes. ICAD'11: International Conference on Alzheimer's Disease, July 16-21, 2011, Paris, France.
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Shen L, Qi Y, Kim S, Nho K, Wan J, Risacher S, Saykin AJ, ADNI (2011) Sparse Bayesian learning for predicting MCI conversion to AD and identifying MRI biomarkers. OHBM’11: Organization for Human Brain Mapping Ann Meeting, Québec City, Canada, June 26-30, 2011.
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Wan J, Kim S, Nho K, Risacher S, Swaminathan S, Bertram L, Jack C, Weiner M, Beg F, Wang L, Saykin AJ, Shen L, ADNI (2011) Influence of candidate AlzGene SNPs on hippocampal shape: A study of the ADNI cohort. OHBM’11: Organization for Human Brain Mapping Ann Meeting, Québec City, Canada, June 26-30, 2011.
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Conroy SK, Nho K, McDonald BC, Risacher SL, Kim S, Shen L, Saykin AJ, ADNI (2011) ESR1 genetic variation differentially influences several aspects of brain morphology by gender in cognitively normal elders: A voxel-based morphometry and SurfStat analysis of the ADNI cohort. OHBM’11: Organization for Human Brain Mapping Ann Meeting, Québec City, Canada, June 26-30, 2011.
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Hibar D, Stein JL, Kohannim O, Jahanshad N, Saykin AJ, Shen L, Kim S, Pankratz N, Foroud F, Huentelman MJ, Potkin SG, Jack CR, Weiner MW, Toga AW, Thompson PM, ADNI (2011) Voxelwise gene-wide association study (vGeneWAS): multivariate gene-based association testing in 731 elderly subjects. OHBM’11: Organization for Human Brain Mapping Ann Meeting, Québec City, Canada, June 26-30, 2011.
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Shen L, Ai H, Liang Y, Wan J, Anthony B, Zhou FC, the CIFASD Consortium (2011) Influence of fetal alcohol on nasal bone development in c57bl/6j mouse models. RSA’11: 34th Annual RSA (Research Society on Alcoholism) Scientific Meeting, June 25-29, 2011, Atlanta, Georgia.
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Wan J, Fang S, Vinci-Booher S, Rogers J, Wetherill L, Robinson L, Hoyme E, Molteno C, Foroud T, Jacobson J, Jacobson S, Shen L, the CIFASD Consortium (2011) Effects of fetal alcohol on 3D facial morphology using surface-based morphometry. RSA’11: 34th Annual RSA (Research Society on Alcoholism) Scientific Meeting, June 25-29, 2011, Atlanta, Georgia.
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Meda S, Narayanan B, Calhoun V, Liu J, Bizzozero-Peron N, Risacher S, Shen L, Saykin AJ, Pearlson G (2010) Parallel independent component analysis successfully identifies clusters of interacting genes and structural mri brain regions from the large-scale ADNI Alzheimer’s/MCI data set. ACNP'10: The ACNP 49th Annual Meeting, Neuropsychopharmacology 35:S347, Miami Beach, Florida, December 5-9, 2010.
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Deters K, Saykin AJ, Swaminathan S, Risacher SL, Nho K, Kim S, Foroud T, Shen L, ADNI (2010) Association of haplotypes of the MAPT gene with Alzheimer's disease and quantitative neuroimaging phenotypes. ABRCMS’10: Annual Biomedical Research Conference for Minority Students, Charlotte, North Carolina, November 10-13, 2010.
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Swaminathan S, Shen L, Risacher SL, Kim S, Nho K, West JD, Foroud T, Yoder KK, Potkin SG, Huentelman MJ, Craig DW, Jagust WJ, Mathis CA, Weiner MW, Saykin AJ, ADNI (2010) Amyloid pathway-based candidate gene analysis of [11C]PiB-PET in the Alzheimer’s Disease Neuroimaging Initiative (ADNI) cohort. ASHG’10: American Society of Human Genetics 60th Annual Meeting, Washington DC, Nov 2-6, 2010.
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Shen L, Ai H, Liang Y, Anthony B, Zhou FC, CIFASD (2010) Effect of fetal alcohol on craniofacial bone development in C57BL/6J mouse models. RSA’10: Annual Research Society on Alcoholism Scientific Meeting, San Antonio, Texas, June 26-30, 2010.
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Wan J, Kim S, McCullough K, Kwangsik Nho, Swaminathan S, West JD, Fang S, McHugh T, Flashman LA, Wishart HA, Rabin LA, Rhodes CH, Guerin SJ, Moore JH, Santulli RB, Saykin AJ, Shen L (2010) Association analysis of candidate SNPs on hippocampal volume and shape in mild cognitive impairment and older adults with cognitive complaints. ICAD’10: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, Honolulu Hawaii, July 10-15, 2010. [Platform talk]
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Kim S, Swaminathan S, Shen L, Risacher SL, Nho K, Foroud T, Shaw LM, Trojanowski JQ, Potkin SG, Huentelman MJ, Craig DW, DeChairo BM, Weiner MW, Saykin AJ, ADNI (2010) Genome-wide association study of CSF biomarkers amyloid beta 1-42, tau and tau phosphorylated at threonine 181 in the ADNI cohort. ICAD’10: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, Honolulu Hawaii, July 10-15, 2010. [Platform talk]
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Swaminathan S, Kim S, Shen L, Risacher SL, Foroud T, Pankratz N, Potkin SG, Huentelman MJ, Craig DW, Weiner MW, Saykin AJ, ADNI (2010) Preliminary analysis of copy number variation in the ADNI cohort. ICAD’10: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, Honolulu Hawaii, July 10-15, 2010.
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Risacher SL, Saykin AJ, Pepin S, WuDunn D, Magee T, Englert J, Flashman LA, Pixley HA, Wishart HA, Shen L, West JD, McDonald BC, O’Neill DP, Santulli RB, Newman RW (2010) Visual contrast sensitivity as a novel biomarker for neurodegeneration in early Alzheimer’s disease, mild cognitive impairment, older adults with cognitive complaints. ICAD’10: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, Honolulu Hawaii, July 10-15, 2010.
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Saykin AJ, Yoder KK, Risacher SL, Magee TR, McDonald BC, Zheng QH, Wang M, Mock BH, Shen L, West JD, Fletcher JW, Farlow MR, Hutchins GD (2010) Neuroinflammation and amyloid deposition: concurrent [11c]PBR28 and [11c]PIB pet in patients with Alzheimer’s disease, mild cognitive impairment, older adults with cognitive complaints. AIC'10: Alzheimer's Imaging Consortium, Honolulu, Hawaii, July 10, 2010. [Platform talk]
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Yoder KK, Risacher SL, MaGee TR, McDonald BC, Zheng QH, Wang M, Mock BH, West JD, Shen L, Hutchins GD, Saykin AJ (2010) Age-related neuroinflammation in non-demented elderly adults: Preliminary findings with the TSPO ligand [11C]PBR28. NRM’10: 8th Int Symp on Functional Neuroreceptor Mapping of the Living Brain, Glasgow, UK, July 22-24, 2010. [Platform talk]
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Ho AJ, Stein JL, Hua X, Lee S, Hibar DP, Toga AW, Saykin AJ, Shen L, Foroud T, Potkin SG, Jack CR, Weiner MW, Raji CA, Lopez OL, Becker JT, Thompson PM (2010) Obesity gene, FTO, is associated with lower brain volumes in 206 healthy elderly subjects. OHBM’10: Organization for Human Brain Mapping Ann Meeting, Barcelona, Spain, June 2010.
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Stein J, Hua X, Lee S, Ho A, Leow A, Toga A, Saykin AJ, Shen L, Foroud T, Pankratz N, Huentelman M, Craig D, DeChairo B, Potkin S, Weiner M, Thompson PM (2010) Voxelwise genome-wide association study (vGWAS). OHBM’10: Organization for Human Brain Mapping Ann Meeting, Barcelona, Spain, June 2010.
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Shen L, Kim S, Risacher SL, Nho K, Swaminathan S, West JD, Foroud TM, Pankratz ND, Moore JH, Sloan CD, Huentelman MJ, Craig DW, DeChairo BM, Potkin SG, Jack CR, Weiner MW, Saykin AJ, ADNI (2010) Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort. IIGC’10: International Imaging Genetics Conference, Irvine, CA, January 16-17, 2010.
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Sheehan K, Wishart H, Roth R, Shen L, Wan J, MacDonald J, Ford J, Seville J, Oliver B, Kasper L (2009) The relationship of thalamic volume and shape to pain in relapsing-remitting MS. ECTRMS'09: The European Conference on Treatment and Research in MS, Dusseldorf, Germany, Sept 2009.
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Shen L, Kim S, West JD, Saykin AJ (2009) Building an imaging genomic browsing system for examining genetic effects on brain. OHBM’09: Organization for Human Brain Mapping Ann Meeting, Neuroimage, 7(Sup. 1):S32, June 18 - 23, 2009, San Francisco, CA. [Platform talk]
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Saykin AJ, Shen L, Risacher SL, Kim S, Nho K, West JD, Foroud TM, the ADNI (2009) Genetic predictors of 12 month change in MRI hippocampal volume in the Alzheimer’s Disease Neuroimaging Initiative cohort: Analysis of leading candidates from the AlzGene database. ICAD’09: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, Vienna, Austria, July 11-16, 2009. [Platform talk]
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Risacher SL, Saykin AJ, Shen L, West JD, Kim S, McDonald BC, the ADNI (2009) Volumetric, cortical thickness, grey matter density changes on MRI over 12 months: Relationship to conversion status in the ADNI cohort. ICAD’09: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, Vienna, Austria, July 11-16, 2009.
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Barkay G, Dzemidzic M, Shen L, Saykin AJ, French AD, Vanam R, Anand A (2009) Brain morphological abnormalities in unmedicated bipolar disorder and major depression: an automated segmentation analysis. SOBP'09: Society of Biological Psychiatry: 64th Annual Scientific Convention, Vancover, Canada, May 14-16, 2009.
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Shen L, Saykin AJ, Firpi HA, West JD, McHugh TL, Wishart HA, Flashman LA, Wessels AM, McDonald BC, Cannon A (2008) Comparison of manual and automated determination of hippocampal volumes in MCI and older adults with cognitive complaints. ICAD’08: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, Chicago, IL, July 26 - 31, 2008.
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Saykin AJ, West JD, Shen L, Firpi HA, Wessels AM, Cannon A, Risacher S, McDonald BC, the Alzheimer's Disease Neuroimaging Initiative (2008) Hippocampal and Distributed Gray Matter Abnormalities in MCI and Early AD in the ADNI Baseline 1.5T MRI Scans: Cross-Sectional Analysis and Relation to Verbal Learning. ICAD’08: Alzheimer’s Association Int. Conf. on Alzheimer's Disease, Chicago, IL, July 26 - 31, 2008.
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Shen L, Saykin AJ, McHugh TL, West JD, Rabin LA, Wishart HA, Chung MK, Makedon FS (2005) Morphometric MRI study of hippocampal shape in MCI using spherical harmonics. AAIC'05: Alzheimer’s Association Int Conf on Prevention of Dementia: Early diagnosis and intervention, P-120, Washington, D.C., June 18-21, 2005.
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Huang H, Shen L, Makedon FS, Gao L, Pearlman JD (2004) Three-dimensional analysis of cardiac magnetic resonance imaging using spherical harmonics model. ACC'04: Annual Scientific Session of the American College of Cardiology, New Orleans, March 7-10, 2004.
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Shen L, Ford JC, Makedon FS, Flashman LA, Saykin AJ (2003) Surface-based morphometric analysis for hippocampal shape in schizophrenia. OHBM’03: Organization for Human Brain Mapping Ann Meeting, Neuroimage, 19(2):e1966-e1970, New York, USA, June 18-22, 2003.
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Saykin AJ, Flashman LA, T. McHugh, C. Pietras, McAllister TW, A. C. Mamourian, R. Vidaver, Shen L, Ford JC, Wang L, Makedon FS (2003) Principal components analysis of hippocampal shape in schizophrenia. SR'03: Schizophrenia Research, 60(1):206, March 29 - April 2, 2003.
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Saykin AJ, Wishart HA, Flashman LA, McAllister TW, T. McHugh, Ford JC, Shen L, Steinberg T, Makedon FS (2002) Structure/function relationships in brain disorders: Strategies for mining volume, shape, lesion and bold fMRI activation data. SBP'02: Society for Biological Psychiatry Meeting, Philadelphia, PA, May 16-18, 2002.
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Ford JC, Makedon FS, Megalooikonomou V, Shen L, Steinberg T, Saykin AJ (2001) Spatial comparison of fMRI activation maps for data mining. OHBM’01: Organization for Human Brain Mapping Ann Meeting, Neuroimage, 13(6):s1302, Brighton, UK, June 10-14, 2001.
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Cheng L, Shen L, Makedon FS, Donnelly AM, Flashman LA, Saykin AJ (2001) TROI: a training and research system for tracing regions of interest in brain images. OHBM’01: Organization for Human Brain Mapping Ann Meeting, Neuroimage, 13(6):s1298, Brighton, UK, June 10-14, 2001.
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Saykin AJ, Flashman LA, Shen L, Ashburner J, Sparling M, Donnelly AM, Makedon FS, Isecke D, Ford JC, Megalooikonomou V, McAllister TW (2001) Hippocampal shape in schizophrenia: A deformation-based morphometric analysis. OHBM’01: Organization for Human Brain Mapping Ann Meeting, Neuroimage,13(6):s1096, Brighton, UK, June 2001.