2023

January 20, 2023:

Review article that captures the discussion at the Telluride science research center phase separation workshop published in J. Mol. Biol.

January 17, 2023:

Miriam featured by ALSA: Early Career ALS Researchers Receive Vital Support through The ALS Association’s Milton Safenowitz Postdoctoral Fellowship

January 17, 2023:

Charlotte's paper on molecular determinants of Karyopherin-β2 chaperone and disaggregation activity published in J. Biol. Chem.

2022

December 22, 2022:

Good luck to Charlotte as she heads off to Johns Hopkins to pursue her post-doc with Jeff Rothstein.

December 15, 2022:

Charlotte's paper on molecular determinants of Karyopherin-β2 chaperone and disaggregation activity published in press at J. Biol. Chem.

December 8, 2022:

Collaborative work with Wilfried Rossoll at Mayo Clinic on nuclear-import receptors and TDP-43 proteinopathy published in Mol. Neurodegen.

December 2, 2022:

Miriam wins best postdoc poster prize at the Dr. George W. Raiziss 38th Annual Retreat at Skytop Lodge, Poconos. PA.

December 2, 2022:

Katie wins best biochemistry poster prize (Kathryn M. Ferguson Award) at the Dr. George W. Raiziss 38th Annual Retreat at Skytop Lodge, Poconos. PA.

December 1, 2022:

Jim presents seminar at the Dr. George W. Raiziss 38th Annual Retreat at Skytop Lodge, Poconos. PA.

November 3, 2022:

Jim presents invited seminar at the Pennsylvania Biotechnology Center, Blumberg Institute, and Fox Chase Chemical Diversity Center in Doylestown, PA.

October 26, 2022:

Charlotte defends her Ph.D. thesis!!!!

October 11, 2022:

Collaborative work with Jernej Ule and Adrian Isaacs on genome-wide RNA binding analysis of C9orf72 poly(PR) dipeptides preprinted at BioRxiv.

September 27, 2022:

Ryan and Alex's paper on Skd3 structure and mechanism with Dan Southworth published in Cell Reports!

September 16, 2022:

Jim presents invited seminar at the Department of Molecular, Cellular, and Developmental Biology at the University of Michigan.

September 15, 2022:

Charlotte's paper on molecular determinants of Karyopherin-β2 chaperone and disaggregation activity prepinted at BioRxiv.

September 6, 2022:

Collaborative work with Schrader, Sanchez-Garcia, and Münch labs on viral disruption by advanced molecular tweezers published in JACS Au!

September 1, 2022:

Katie is awarded a Ruth L. Kirschstein National Research Service Award (NRSA) from the National Institute of Neurological Disorders and Stroke (NINDS)!

August 19, 2022:

Jim presents invited seminar at Robert Packard Center, Pederson Brain Science Institute at Johns Hopkins University.

August 18, 2022:

R21 proposal funded by the National Institute of Aging (NIA)!

July 29, 2022:

Miriam wins a Milton Safenowitz Post-Doctoral Fellowship from the ALS Association!

July 28, 2022:

Jim presents invited seminar at the Molecular and Cellular Neurobiology Gordon Research Conference at Ventura Beach, CA.

July 17, 2022:

Jim presents invited seminar at the Whitehead Institute for Biomedical Research for Sue-palooza 2022.

July 8, 2022:

Good luck to Erica as she heads off to be a visiting assistant professor at Ursinus College.

July 1, 2022:

Good luck to Jack as he heads off to MIT to pursue his Ph.D.

June 16, 2022:

Miriam earns post-doctoral fellowship from Swiss National Science Foundation (SNSF)!

June 15, 2022:

Good luck to Ben as he heads off to Thomas Jefferson University to pursue his M.D.

May 26, 2022:

JiaBei presents seminar at Dr. George W. Raiziss Rounds Seminar Series.

May 18, 2022:

Collaborative work with Yale Goldman and Kathy Liu on DDX3X/Y phase separation published in Mol. Cell.

May 17, 2022:

Collaborative work with Leeanne McGurk and May Khanna on HspA5 and TDP-43 published in Scientific Reports.

May 16, 2022:

Jim presents invited seminar at Dept. of Molecular Biophysics and Biochemistry at Yale University.

May 16, 2022:

Congratulations to our graduating Penn seniors Max Tjauw and Sylvanne Braganza!

May 12, 2022:

Collaborative work with Iris Lindberg on proSAAS and TDP-43 published in ACS Chem Neurosci.

May 11, 2022:

Zarin passes her prelim!!!

May 9, 2022:

Jim presents invited seminar at the 'Molecular Bases of Proteinopathies' zoominar series at the University of Michigan.

May 4, 2022:

Congratulations to our graduating Temple senior George Padilla!

May 3, 2022:

Jim presents seminar at Target ALS Annual Meeting as part of consortium with Chris Donnelly and Merck.

April 29, 2022:

Jim co-chairs session and presents invited seminar at the Cold Spring Harbor Protein Homeostasis Meeting.

April 28, 2022:

Collaborative work with Paul Taylor and Carsten Bönnemann on hnRNPA2 variants causing early-onset oculopharyngeal muscular dystrophy published in Nat. Comm.

April 26, 2022:

Jim presents invited seminar at the Condensate Colloquium Series.

April 25, 2022:

Jim presents Grand Rounds at the Penn Alzheimer's Disease Research Center.

April 22, 2022:

Ryan wins the 2022 Saul Winegrad Award for best dissertation by a PGG student!

April 14, 2022:

Katie's Preview on TMEM106B(120-254) fibrils is published in Cell.

April 5, 2022:

Katie wins Penn Prize for Teaching Excellence by Graduate Students!

April 4, 2022:

Charlotte, Katie, and Jack present posters at the 2022 Annual ASBMB Meeting in Philadelphia.

April 4, 2022:

Jack, Alexis, and Lauren win National Science Foundation Graduate Research Fellowships!

April 3, 2022:

Charlotte presents seminar at the 2022 Annual ASBMB Meeting in Philadelphia.

April 3, 2022:

Zarin, Ben, George, Evan, and Erica present posters at the 2022 Annual ASBMB Meeting in Philadelphia.

April 2, 2022:

JiaBei presents poster at the 2022 Annual ASBMB Meeting in Philadelphia.

March 31, 2022:

JiaBei's review with Aaron Lucius on AAA+ protein mechanisms is published in Biochem. Soc. Trans.

March 23, 2022:

Jim presents invited seminar at Telluride Science Research Center Workshop on phase separation in biology and disease.

March 22, 2022:

Lina is accorded an Honorable Mention from the Ford Foundation.

March 1, 2022:

Jim presents invited seminar at the 22nd Annual Packard Center Symposium.

February 28, 2022:

Charlotte and Katie present posters at the 22nd Annual Packard Center Symposium.

February 24, 2022:

The Packard Center for ALS Research at Johns Hopkins funds our work on TDP-43.

February 23, 2022:

Collaborative work with Aaron Gitler, Len Petrucelli, and Sua Myong et al. on TDP-43 repressing cryptic exon inclusion in UNC13A published in Nature. See also accompanying study from Ward & Fratta labs, and also News & Views and STAT news article.

February 21, 2022:

Charlotte presents seminar at 66th Biophysical Society Annual Meeting in San Francisco.

February 18, 2022:

Collaborative work with Anthony Leung and Sua Myong on FUS-PAR interactions published in Mol. Cell.

February 17, 2022:

Ryan and Alex's paper on Skd3 structure and mechanism with Dan Southworth posted on BioRxiv

February 8, 2022:

Jack presents seminar at RNP Discussion Group.

February 3, 2022:

Collaborative work with Daniel Link on Skd3 (human ClpB) variants causing severe congenital neutropenia featured in a Commentary in Blood.

January 5, 2022:

Hana and Charlotte get the cover of J. Mol. Biol.

2021

December 8, 2021:

Hana's News & Views on TDP-43 fibril structure published in Nature.

December 8, 2021:

Collaborative work with Leeanne McGurk and May Khanna on HspA5 and TDP-43 preprinted at Research Square.

December 2, 2021:

Hana wins the Ruth Keris Award for Departmental and Graduate Group Service!

December 2, 2021:

JiaBei wins best postdoc poster prize at the Dr. George W. Raiziss 37th Annual Retreat at Penn Museum!

December 2, 2021:

Charlotte presents seminar at the Dr. George W. Raiziss 37th Annual Retreat at Penn Museum.

November 12, 2021:

Jim presents seminar at the Penn IOA/CNDR Retreat.

November 10, 2021:

Jim presents seminar at the Symposium on Structural Biology 2021 (SimBE 2021).

November 8, 2021:

Hana presents seminar at the Second Annual Diversity and Science Symposium.

November 4, 2021:

Ryan presents seminar at MitoCare.

November 3, 2021:

Jim presents seminar at the Cell Symposium on Biological Assemblies: Phase transitions and more.

November 2, 2021:

Charlotte presents poster at the Cell Symposium on Biological Assemblies: Phase transitions and more.

October 31, 2021:

Collaborative work with Marmorstien lab on N-alpha-acetylation of Huntingtin protein published in J. Biol. Chem.

October 29, 2021:

Good luck to Ryan as he heads off to NIH to pursue his post-doc with Richard Youle.

October 20, 2021:

Ryan defends his Ph.D. thesis!!!!

October 12, 2021:

Katie presents seminar at RNP Discussion Group.

October 8, 2021:

Jim presents invited seminar at The Department of Chemistry at Villanova University.

October 5, 2021:

Jim presents invited seminar in the Cellular and Protein Homeostasis Webinar Series hosted by Paolo De Los Rios, Pierre Goloubinoff, Nadinath Nillegoda, and Alessandro Barducci.

September 24, 2021:

Ryan presents seminar at mitochondrial homeostasis and human disease EMBO workshop in Girona, Spain.

September 23, 2021:

Jim presents invited virtual seminar at the Molecular & Cell Biology & Genetics Seminar Series at Drexel College of Medicine.

September 15, 2021:

Lina starts her PENN-PORT post-doctoral fellowship in the lab.

September 10, 2021:

Jim presents invited virtual seminar at the Second UCL Queen Square Motor Neuron Disease Centre International Symposium.

August 31, 2021:

Good luck to April as she heads off to Lacerta Therapeutics.

August 28, 2021:

Hana and Charlotte's review on nuclear-import receptors is published in J. Mol. Biol.

August 25, 2021:

Hana wins an Alzheimer’s Association Research Fellowship (AARF)!

August 18, 2021:

Collaborative work with Xiaolu Yang on DAXX as a new type of protein-folding enabler published in Nature. See Penn press release.

August 12, 2021:

Jim presents virtual seminar for RBNC Therapeutics (Neumora).

August 10, 2021:

Collaborative work with Martina Hallegger and Jernej Ule on TDP-43 condensation and regulation published in Cell.

August 4, 2021:

Collaborative work with AstraZeneca, Steve Finkbeiner, and Aaron Gitler on p38alpha and TDP-43 preprinted at BioRxiv.

July 22, 2021:

Collaborative work with Paul Taylor and Jonathan Baets on hnRNPA1 variants in hereditary motor neuropathy, ALS, and myopathy published in JCI Insight.

July 20, 2021:

Collaborative work with Anthony Leung and Sua Myong on FUS-PAR interactions preprinted at Cell Press Sneak Peek.

July 2, 2021:

Katie selected as a 2021 predoctoral trainee for the Structural Biology & Molecular Biophysics (SBMB) training program.

June 25, 2021:

Jim presents virtual seminar at FASEB Meeting 'Protein Aggregation Conference: Function, Dysfunction, and Disease'.

June 15, 2021:

Charlotte, Alexis, and Lauren's review of higher-order organization of biomolecular condensates published in Open Biology.

June 11, 2021:

Collaborative work with Daniel Link on Skd3 (human ClpB) variants causing severe congenital neutropenia published in Blood.

June 10, 2021:

Jim presents invited seminar at the Middle Atlantic Regional Meeting of the American Chemical Society 2021.

June 8, 2021:

Hana presents seminar at RNP Discussion Group.

June 2, 2021:

Onsite research of Shorter lab ramps up in Phase 3 reopening (100% occupancy).

May 28, 2021:

Good luck to Allan as he heads off to pursue his M.D. at The University of Minnesota.

May 19, 2021:

Erica's Preview published in Neuron.

May 18, 2021:

Katie passes her prelim!!!

May 17, 2021:

Congratulations to Andrew Lam on winning a Penn Alumni Student Award of Merit!

May 17, 2021:

Congratulations to our graduating Penn seniors Sarah Khan, Baotram Nguyen, Andrew Lam, and Kenneth Li!

May 10, 2021:

Jim presents invited virtual seminar at SickKids at The University of Toronto.

May 4, 2021:

Jim presents seminar at virtual Target ALS Annual Meeting as part of consortium with Chris Donnelly and Merck.

May 4, 2021:

Charlotte's review published in Dis. Mod. Mech.

April 27, 2021:

Zach wins the 2021 Saul Winegrad Award for best dissertation by a BMB student!

April 26, 2021:

Bede presents invited virtual seminar at the ASBMB Protein Interest Group.

April 23, 2021:

Jim presents invited virtual seminar at the Advances in Biomedical Research Seminar Series at The University of Ottawa.

April 16, 2021:

Collaborative work with Paul Taylor and Carsten Bönnemann on hnRNPA2 variants in early-onset oculopharyngeal muscular dystrophy preprinted in MedRxiv.

April 14, 2021:

Jim serves as Sterling Drug Visiting Lecturer virtually at the Department of Pharmacology & Experimental Therapeutics at Boston University.

April 5, 2021:

Good luck to Bede as he heads off to Dewpoint Therapeutics.

March 19, 2021:

Bede and Eddie present seminar at the virtual Group Meeting with May Khanna's lab!

March 17, 2021:

Bede and Jack present seminars at the virtual Gitler-Myong-Shorter-Ha (GMSH) Meeting!

March 16, 2021:

Eddie, Ryan, and Charlotte present seminars at the virtual Gitler-Myong-Shorter-Ha (GMSH) Meeting!

March 11, 2021:

Jim delivers virtual keynote seminar at the CReATe Consortium Annual Meeting.

March 8, 2021:

Jim presents invited virtual seminar at the 21st Annual Packard Center Symposium.

March 8, 2021:

Bede presents invited virtual seminar at Syracuse University Biology Department.

March 4, 2021:

Jim presents invited virtual seminar at the Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences.

February 26, 2021:

Hana presents invited virtual seminar at the B&B/BMB Mini-Symposium.

February 23, 2021:

Jim presents invited virtual seminar at the Department of Biochemistry at West Virginia University.

February 16, 2021:

Jim presents invited virtual seminar at Biophysics of Amyloid Formation Meeting at Ulm University.

February 5, 2021:

April's review published in BBA.

February 4, 2021:

Charlotte's spotlight published in Trends Genet.

February 3, 2021:

Collaborative work with Paul Taylor and Jonathan Baets on hnRNPA1 variants in hereditary motor neuropathy, ALS, and myopathy preprinted in MedRxiv.

January 11, 2021:

Bede and Linda's review on FUS and TDP-43 phases published in Trends Biochem. Sci.

2020

December 30, 2020:

Bede's review on biochemical timekeeping via reentrant phase transitions published in J. Mol. Biol.

December 22, 2020:

Collaborative work with Dorothee Dormann on nuclear-import receptors and c9DPRs published in Cell Rep.

December 16, 2020:

Jim presents invited virtual seminar at Faze Medicines.

December 15, 2020:

Zach's paper on therapeutic genetic variation in Hsp104 homologs published in eLife

December 11, 2020:

Hana's artwork featured on the cover of Emerg. Top. Life Sci.

December 9, 2020:

Jim presents invited virtual seminar at Institute for Quantitative Biomedicine at Rutgers University.

December 5, 2020:

Ryan's methods paper published in Bio-Protocol

December 4, 2020:

Hana presents invited virtual seminar at Cold Spring Harbor Laboratory Meeting: Neurodegenerative Diseases: Biology & Therapeutics.

December 1, 2020:

Collaborative work with Xiaolu Yang on TRIM disaggregases published in Cell Rep.!

November 13, 2020:

Ryan presents invited virtual seminar at Cold Spring Harbor Laboratory Meeting: Protein Homeostasis in Health and Disease.

November 13, 2020:

Jim presents invited seminar at the RNA at the Bench and Bedside II Virtual Conference.

November 9, 2020:

Shariq presents poster at the Annual Biomedical Research Conference for Minority Students (ABRCMS) 2020.

November 6, 2020:

Collaborative work with Sua Myong on FUS variants published in Mol. Cell!

October 26, 2020:

Hana's renews her AstraZeneca post-doctoral fellowship.

October 15, 2020:

Hana presents virtual seminar for AstraZeneca Neuroscience.

October 13, 2020:

Jim presents invited virtual seminar for Florida Atlantic University Brain Institute.

October 13, 2020:

Bede presents seminar at RNP Discussion Group.

September 19, 2020:

Charlotte and Ryan present at FRD!

September 14, 2020:

Collaborative work with Schrader, Sanchez-Garcia, and Münch labs on viral disruption by molecular tweezers published in JACS! See also, Chembites coverage.

September 14, 2020:

Erica starts her PENN-PORT post-doctoral fellowship in the lab.

September 4, 2020:

Good luck to Zach as he heads off to NIH to pursue his post-doc with Priyanka Narayan.

September 2, 2020:

Hana's co-first author paper on collaborative work with Yong-Jie Zhang and Len Petrucelli on poly(GR) stimulating TDP-43 aggregation out in Sci. Trans. Med.! See also, Penn press release, Alzforum coverage, Fierce biotech story, and Packard Center.

September 1, 2020:

Good luck to Eddie Chuang as he heads off to Rutgers to pursue his post-doc with Monica Driscoll in the INSPIRE IRACDA program.

August 26, 2020:

Jim presents invited virtual seminar for the Northwestern, Harvard, Stanford, UCSF, and Scripps Proteostasis Consortium.

August 25, 2020:

Jim becomes consultant for Dewpoint Therapeutics.

August 20, 2020:

Lin's methods paper published in Bio-Protocol

August 19, 2020:

Eddie defends his Ph.D. thesis!!!!!

August 10, 2020:

April's spotlight published in Trends Neurosci.

August 6, 2020:

Bede presents invited seminar at Telluride Science Research Center Virtual Worshop: Biomolecular Interactions in the Cellular Environments.

July 31, 2020:

Good luck to Jacob as he heads off to UMass to pursue his Ph.D.!

July 24, 2020:

Good luck to Linda as she heads off to Drexel University to pursue her MD/Ph.D.!

July 22, 2020:

Bede presents invited seminar to Dewpoint Therapeutics.

July 14, 2020:

Zach defends his Ph.D. thesis!!!!!

July 13, 2020:

Onsite research of Shorter lab ramps up in Phase 2 reopening (50% occupancy).

July 8, 2020:

Hana's review is published in Emerg. Top. Life Sci.

July 1, 2020:

April wins a post-doctoral fellowship from the American Parkinson Disease Association!

June 30, 2020:

Good luck to Alexis as she heads off to UCSF to pursue her Ph.D.!

June 23, 2020:

Ryan's paper on Skd3 published in eLife.

June 8, 2020:

Onsite research of Shorter lab resumes in Phase 1 reopening (25% occupancy).

May 29, 2020:

Bede presents invited seminar at Alzheimer's Afternoons online seminar series.

May 26, 2020:

Charlotte presents virtual poster at the 25th Annual RNA Society Meeting.

May 24, 2020:

Congratulations to our graduating Swarthmore senior Runa Cheng!

May 19, 2020:

Jim presents invited virtual seminar for the Cell & Molecular Biology Seminar Series at St. Jude Children’s Research Hospital.

May 18, 2020:

Congratulations to our graduating Penn seniors Mustafa Salim and Lauren Drake!

April 23, 2020:

Bede presents invited seminar at IDPSIG and friends virtual symposium.

April 20, 2020:

Collaborative work with Dan Southworth at UCSF and Aaron Lucius at UAB on cryo-EM structures of ClpAP translocating substrate published in Nat. Struct. Mol. Biol.!

April 18, 2020:

Collaborative work with Iris Lindberg on proSAAS phase separation posted on BioRxiv

April 16, 2020:

Korrie's paper on tuning Hsp104 specificity to selecively detoxify alpha-synuclein posted on BioRxiv

April 16, 2020:

Preview with Aaron Gitler, Taekjip Ha, and Sua Myong published in Mol. Cell!

April 10, 2020:

Collaborative work with Walter Englander on HXMS of potentiated Hsp104 variants is published in PNAS!!

April 8, 2020:

Hana's Preview is published in Neuron!

March 31, 2020:

Katie is accorded an Honorable Mention from the National Science Foundation.

March 26, 2020:

Zach's paper on therapeutic genetic variation in Hsp104 homologs posted on BioRxiv

March 17, 2020:

All onsite research activities of Shorter lab are suspended due to COVID-19.

March 11, 2020:

Target ALS fund our Industry-Led Consortium on TDP-43 LLPS with Merck, Vivid, and Chris Donnelly!

March 5, 2020:

Ryan presents seminar at the Gitler-Myong-Shorter-Ha (GMSH) Meeting at Johns Hopkins University!

March 4, 2020:

Zach and JiaBei present seminars at the Gitler-Myong-Shorter-Ha (GMSH) Meeting at Johns Hopkins University!

March 3, 2020:

Chris Donnelly presents on collaborative work with Shorter lab at The 20th Annual Packard Center Symposium.

February 11, 2020:

Bede presents seminar at RNP Discussion Group.

January 29, 2020:

Jim presents invited seminar at Keystone Symposium: AAA+ proteins from atomic structures to organisms.

January 28, 2020:

Review with AstraZeneca on ALS clinical trials accepted at Med. Res. Rev.!

January 27-28, 2020:

Amber, Ryan, Allan, Jacob, Eddie Barbieri, Zach, and JiaBei present posters at Keystone Symposium: AAA+ proteins from atomic structures to organisms.

January 27, 2020:

Ryan presents invited seminar at Keystone Symposium: AAA+ proteins from atomic structures to organisms.

January 22, 2020:

Jim presents invited seminar at the Dementia Discovery Fund.

January 18, 2020:

Ryan's paper on Skd3 posted on BioRxiv

January 13, 2020:

JiaBei wins the 2nd Annual Warren Alpert Foundation Distinguished Scholars Fellowship!

January 10, 2020:

R21 proposal funded by the National Institute of Aging (NIA)!

2019

December 30, 2019:

Review with Dean Brown and Heike Wobst on emerging small-molecule therapeutics for ALS/FTD published in Bioorganic & Medicinal Chemistry Letters!

December 27, 2019:

XF-MS study of Hsp104 published in J. Biol. Chem.!

December 11, 2019:

Collaborative work with Gary Kleiger, Rich Gardner, and colleagues on Ssa1/Ssa2 in nuclear protein-quality control published in Mol. Biol. Cell!

December 9, 2019:

Zach presents poster at the ASCB|EMBO 2019 Meeting in Washington D.C.

December 6, 2019:

Bede presents seminar at the Dr. George W. Raiziss 36th Annual Retreat at Skytop Lodge, Poconos. PA!

December 6, 2019:

Eddie Barbieri wins best postoc poster prize at the Dr. George W. Raiziss 36th Annual Retreat at Skytop Lodge, Poconos. PA!

December 5, 2019:

Jim's Department of Defense Amyotrophic Lateral Sclerosis Research Program (ALSRP) Therapeutic Idea Award recommended for funding!

November 16, 2019:

Alexis presents poster at Annual Biomedical Research Conference for Minority Students (ABRCMS) in Anaheim, CA.

November 13, 2019:

Bede's Spotlight published in Trends. Biochem. Sci.

November 12, 2019:

Eddie Chuang presents seminar at the PGG symposium at the National Constitution Center and wins the John S. O'Brien Award for best oral presentation!

November 8, 2019:

JiaBei and Eddie Chuang present at FRD!

October 28, 2019:

Collaborative work with Dan Southworth at UCSF and Aaron Lucius at UAB on cryo-EM structures of ClpAP translocating substrate posted on BioRxiv

October 17, 2019:

Collaborative work with Sua Myong and colleagues on ALS/FTD-linked FUS mutants published in Molecular Cell!

October 17, 2019:

Jim presents invited seminar to Dewpoint Therapeutics.

October 8, 2019:

Charlotte presents seminar at RNP Discussion Group.

October 3, 2019:

Collaborative work with Shuying Sun and colleagues on DDX3X as a repressor of RAN translation published in Neuron! See also Preview by Adrian Isaacs et al. See Packard Center press release.

September 30, 2019:

Eddie Barbieri is awarded a Ruth L. Kirschstein National Research Service Award (NRSA) from the National Institute of Neurological Disorders and Stroke (NINDS)!

August 20, 2019:

Amber, JiaBei, and Meredith's paper on mining disaggregase sequence space is published in Cell Reports!

August 15, 2019:

ALSA funds our work on TDP-43 and FUS phase separation!

August 1, 2019:

Bede presents seminar at the 38th Summer Symposium in Molecular Biology at Penn State.

August 1, 2019:

Hsp104 on the cover of Cold Spring Harb. Perspect. Biol.

July 31, 2019:

Bede presents poster at the 38th Summer Symposium in Molecular Biology at Penn State.

July 30, 2019:

Ryan wins a Blavatnik Family Fellowship in Biomedical Research!

July 20, 2019:

Jim delivers Keynote at the Amyotrophic Lateral Sclerosis and Related Motor Neuron Diseases Gordon Research Seminar at Mount Snow, VT!

July 11, 2019:

The G. Harold & Leila Y. Mathers Foundation funds our work on disaggregases!

July 1, 2019:

Bede wins Post-Doctoral fellowship from the BrightFocus Foundation!

July 1, 2019:

Jim becomes a member of the Drug Discovery for the Nervous System (DDNS) Study Section.

June 18, 2019:

Korrie defends her Ph.D. thesis!!!!!

June 17, 2019:

Mariana Torrente returns from Brooklyn College for special seminar at Penn!

June 5, 2019:

Collaborative work with Meredith Jackrel at Wash U on Hsp104 variants mitigating toxicity of FUS-CHOP and EWS-FLI published in J.Biol.Chem.

June 3, 2019:

Collaborative work with Dan Southworth at UCSF on cryo-EM structures of ClpB translocating substrate published in Nat. Comm.

May 8, 2019:

Jim, Bede, Eddie Barbieri, Charlotte, Linda, and Hana present seminars at the Gitler-Myong-Shorter-Ha (GMSH) Meeting at Penn!

April 30, 2019:

Jim presents seminar at Target ALS Annual Meeting.

April 22, 2019:

Daniel Rodriguez, Baotram Nguyen, and Gracelynn Soesanto cover work on FUS, ALS, and Kapbeta-2 in video: The Implication of Mutated FUS in ALS.

April 22, 2019:

Addie Shelley, Sean Na, and Joseph Chong cover our work in video: Hsp104 Disaggregation of Amyloid Fibrils

April 22, 2019:

Eddie Barbieri featured by ALSA.

April 17, 2019:

Collaborative work with Sandrine Da Cruz, Don Cleveland, and Chris Donnelly featured on the cover of Neuron!

April 15, 2019:

Charlotte is awarded a Ruth L. Kirschstein National Research Service Award (NRSA) from the National Institute of Neurological Disorders and Stroke (NINDS)!

April 12, 2019:

Amber and Korrie present at FRD!

April 5, 2019:

Collaborative work with Aaron Lucius on Hsp104 translocase activity is published in Biophys. J.!!

April 4, 2019:

Jim's editorial is published in J. Biol. Chem.

March 27, 2019:

Collaborative work with Walter Englander on HXMS of Hsp104 is published in PNAS!!

March 22, 2019:

Zach & Korrie's Biophysical Perspective is published in Biophys. J.!

March 20, 2019:

Jim presents colloquium at the Dept. of Chemistry & Biochemistry, University of Toledo.

March 12, 2019:

Bede presents seminar at RNP Discussion Group.

March 7, 2019:

Collaborative work with Sandrine Da Cruz and Don Cleveland on neurotoxic TDP-43 phase separation is published in Neuron! See also Preview by Ben Wolozin and Alzforum coverage.

March 5, 2019:

Bede presents poster at the 64th Annual Meeting of the Biophysical Society in Baltimore.

March 4, 2019:

JiaBei presents poster at the 64th Annual Meeting of the Biophysical Society in Baltimore.

March 4, 2019:

Jim presents seminar at The 19th Annual Packard Center Symposium

March 2, 2019:

Jim presents invited seminar for the IDP subgroup at the 64th Annual Meeting of the Biophysical Society in Baltimore!

March 1, 2019:

Good luck to Lin as she heads off to establish her own research program as an Assistant Professor in the Department of Biochemistry & Molecular Biology at Jefferson University!

February 27, 2019:

Collaborative work with Chris Donnelly on RNA antagonizing toxic TDP-43 phase separation is published in Neuron! See Preview by Ben Wolozin, Pitt press release, Alzforum, and Nature coverage.

February 27, 2019:

Jim presents invited seminar at the AFTD workshop in Miami.

February 25, 2019:

Jim presents invited seminar at Pathology & Lab Medicine Grand Rounds at Penn.

February 20, 2019:

Bede wins poster prize at the NYAS meeting on phase separation in biology and disease!

February 19, 2019:

Baotram and Ouen featured in Daily Pennsylvanian as leaders of Penn Heroes Club!

February 14, 2019:

Collaborative work with Len Petrucelli on C9orf72 poly(PR) toxicity is published in Science!! See Alzforum coverage.

February 12, 2019:

Review with Dan Southworth published in Cold Spring Harb. Perspect. Biol.!

February 12, 2019:

AstraZeneca visit Penn for Target ALS consortium update.

February 5, 2019:

Target ALS/ALS Finding a cure (ALSFAC) Industry-Led Consortium with AstraZeneca, Aaron Gitler, and Steve Finkbeiner recommended for funding!

February 1, 2019:

Jim presents invited seminar at the Stanford Brain Rejuvenation Project Mini-Symposium at the Wu Tsai Neurosciences Institute at Stanford.

January 31, 2019:

Jim visits the Southworth lab at UCSF.

January 18, 2019:

R21 proposal funded by the National Institute of Aging (NIA)!

January 16, 2019:

Lin and Charlotte's review on nuclear-import receptors published in Trends Cell Biol.!

January 16, 2019:

Disaggregase strategy featured in Science.

2018

December 27, 2018:

Zach's paper in collaboration with Wah Chiu and Andrzej Joachimiak on C. thermophila Hsp104 structure and function published in Structure.

December 21, 2018:

Science features Lin Guo's Cell paper among others as a runner-up for the 2018 Breakthrough of the Year (How cells marshal their contents).

December 19, 2018:

ALS Research Forum features our collaborative work with Nancy Bonini.

December 17, 2018:

Eddie Barbieri's News & Views published in Nat. Neurosci.!

December 12, 2018:

Leeanne, Ed, and Lin's latest paper published in Biochemistry!

December 11, 2018:

Lin and Charlotte present posters at the ASCB|EMBO 2018 Meeting in San Diego.

December 10, 2018:

Zach, Eddie Chuang, and Ryan present posters at the ASCB|EMBO 2018 Meeting in San Diego.

December 7, 2018:

The Role of AAA+ Proteins in Protein Repair and Degradation, ebook published online.

December 3, 2018:

Bede's Preview published in Dev. Cell.

December 1, 2018:

Jim presents invited seminar at Cold Spring Harbor Laboratory Meeting. Neurodegenerative Diseases: Biology & Therapeutics.

November 27, 2018:

Jim presents invited seminar at the Dept. of Anatomy and Neurobiology, University of Maryland School of Medicine in Baltimore, MD.

November 19, 2018:

Hana is awarded an AstraZeneca Post-Doctoral Fellowship!

November 13, 2018:

Lin presents seminar at RNP Discussion Group.

November 9, 2018:

Ryan wins poster prize at the Dr. George W. Raiziss 35th Annual Retreat at Skytop Lodge, Poconos. PA!

November 8, 2018:

Bede is awarded an American Heart Association post-doctoral fellowship!

November 8, 2018:

Jim presents invited seminar at the USF Health Byrd Alzheimer’s Center and Research Institute in Tampa, FL.

November 2, 2018:

Jim presents invited seminar at the 2nd Annual Massachusetts ALS Partnership Symposium in Cambridge, MA.

October 31, 2018:

Collaborative work with Roy Parker on TDP-43 myogranules is published in Nature! See also news story at Medical Xpress and News & Views by Lindsay Becker and Aaron Gitler.

October 25, 2018:

Zach wins poster prize at the CNDR 2018 Marian S. Ware Research Retreat!

October 25, 2018:

Lin presents invited seminar at the CNDR 2018 Marian S. Ware Research Retreat.

October 24, 2018:

Jim presents invited seminar at the 18th Eibsee Meeting on Cellular Mechanisms of Neurodegeneration at Lake Eibsee, Germany.

October 23, 2018:

Ryan presents seminar at the PGG symposium at the National Constitution Center and wins the John S. O'Brien Award for best oral presentation!

October 18, 2018:

Jim presents invited seminar at VIB-KU Leuven Center for Brain & Disease Research.

October 8, 2018:

Lin is selected as a Class of 2018 Stat Wunderkind!

October 4, 2018:

Lab is featured in the official ALSA blog!

September 26, 2018:

Collaborative work with Dan Southworth at UCSF on cryo-EM structures of ClpB translocating substrate posted on BioRxiv

September 13, 2018:

Jim presents invited seminar at Dept. of Pharmacology at UTSW.

September 8, 2018:

Editorial with Walid Houry on the The Role of AAA+ Proteins in Protein Repair and Degradation published in Front. Mol. Biosci.

September 5, 2018:

Emily, Mustafa, Lauren, and Baotram present posters at CURF Research Expo and Open House!

September 5, 2018:

Ryan and Korrie present seminars at the MINS “Year of Neurodegenerative Research” Student Kick-off Event!

August 29, 2018:

Collaborative work with Bonini lab led by Leeanne McGurk on nuclear poly(ADP-ribose) as a therapeutic target in ALS is published in Acta. Neuropathol. Commun.

August 27, 2018:

Jim delivers Keynote Lecture at the LiveLikeLou Symposium at the University of Pittsburgh Brain Institute.

August 9, 2018:

Collaborative work with Bonini lab led by Leeanne McGurk and Ed Gomes on poly(ADP-ribose) preventing pathological TDP-43 phase separation is published in Mol. Cell! See also Penn press release, news stories at Fierce Biotech and Endpoints, and Preview by Stepen Boeynaems and Aaron Gitler

July 25, 2018:

Ed Gomes' review is published in J. Biol. Chem.

July 18, 2018:

Eddie Chuang wins a Blavatnik Family Fellowship in Biomedical Research! Meet Eddie and the other 2018 recipients here.

July 17, 2018:

Collaborative work on FUS with Steven Boeynaems and Ludo Van Den Bosch published in Cell Reports!

July 9, 2018:

Ryan is awarded a Ruth L. Kirschstein National Research Service Award (NRSA) from the National Institute of Aging (NIA)!

July 8, 2018:

Charlotte selected as a 2018 predoctoral trainee for Dr. Josh Wand’s T32 Grant: Structural Biology and Molecular Biophysics Training Program

July 1, 2018:

Jim becomes Professor of Biochemistry and Biophysics.

June 25, 2018:

Collaborative work with Steve Bart and Paul Bates on seminal amyloid enhancement of Ebola virus infection published in PNAS. See also Penn press release.

June 24-29, 2018:

Korrie attends the 68th Lindau Nobel Laureate Meeting in Lindau, Germany.

June 21, 2018:

Jim presents two invited seminars at the Annual ENCALS Meeting in Oxford, U.K.

June 16, 2018:

Good luck to Sanny as she heads off to pursue her M.D./Ph.D. at NYU!

June 14, 2018:

Eddie Barbieri wins a Milton Safenowitz Post-Doctoral Fellowship from the ALS Association!

June 12, 2018:

Good luck to Ed Gomes as he heads off to pursue his M.D. at the Perelman School of Medicine at the University of Pennsylvania!

June 7, 2018:

Jim presents invited seminar at the Lankenau Institute for Medical Research.

May 29, 2018:

Good luck to Elena as she heads off to the University of Chicago to pursue her Ph.D.!

May 15, 2018:

Good luck to Olivia as she heads off to Stanford to pursue her M.D./Ph.D.!

May 15, 2018:

Good luck to Saurabh as he heads off to pursue his M.D. at Columbia University!

May 15, 2018:

Good luck to Jacob as he heads off to pursue his M.Res. in Molecular and Cellular Biosciences at Imperial College London!

May 14, 2018:

Zach presents poster at the EMBO|EMBL Symposium on Cellular Mechanisms Driven by Liquid Phase Separation in Heidelberg, Germany.

May 8, 2018:

Elena presents poster at the 7th Annual PREP Regional Symposium at Albert Einstein College of Medicine.

May 3, 2018:

Lin presents seminar at Target ALS Annual Meeting.

May 1, 2018:

Jim presents seminar at Target ALS Annual Meeting.

April 30, 2018:

Korrie presents seminar at AstraZeneca Neuroscience.

April 23, 2018:

Jim delivers the Cecile M. Pickart Memorial Lecture at the Dept. of Biochemistry and Molecular Biology at Johns Hopkins Bloomberg School of Public Health.

April 20, 2018:

Charlotte passes her candidacy exam!!

April 19, 2018:

Jim presents invited seminar at the Dept. of Biochemistry at Emory University.

April 19, 2018:

Lin, Hong Joo, and Henry's paper on nuclear-import receptors reversing aberrant phase transitions of RNA-binding proteins with prion-like domains is published in Cell! See also Mini-Review by Mikhaleva & Lemke in Cell, Penn press release, ALS Research Forum, and Alzforum.

April 17, 2018:

Alex Zhou covers our work on Hsp104 in video: Utilizing Protein Disaggregase Chaperones to Treat Neurodegenerative Diseases: Hsp104.

April 16, 2018:

Bede is featured in eLife.

April 13, 2018:

Eddie, Acacia, and Christina's review on amyloid assembly and disassembly published in J. Cell Sci.!

April 12, 2018:

Mustafa publishes video: Disaggregation of alpha-synuclein amyloid fibrils by Hsp70.

April 12, 2018:

Amber, JiaBei, and Megan's paper is published in FEMS Yeast Res. for a special issue to commemorate Sue Lindquist.

March 27, 2018:

Phase separation review published in Trends Cell Biol.

March 20, 2018:

Jim promoted to Professor of Biochemistry and Biophysics, effective July 1!

March 15, 2018:

Sanny's Preview published in Mol. Cell.

March 14, 2018:

Nature news feature on phase separation.

March 13, 2018:

Lin presents seminar at RNP Discussion Group.

March 6, 2018:

Jim presents seminar at The 18th Annual Packard Center Symposium

March 1, 2018:

Collaborative work with Jiou Wang's lab is published in Mol. Cell.

February 27, 2018:

Korrie is selected to participate in the 68th Lindau Nobel Laureate Meeting!

February 26, 2018:

Ryan presents SPATT seminar.

February 21, 2018:

Ryan presents poster at the 62nd Annual Biophysical Society Meeting in San Francisco.

February 20, 2018:

Jim presents invited seminar at the Davee Dept. of Neurology, Northwestern University Feinberg School of Medicine.

February 19, 2018:

Sanofi supports our work on disaggregases.

February 12, 2018:

Eddie Chuang presents SPATT seminar.

February 9, 2018:

Jim presents invited seminar at the Dept. of Molecular Biology and Genetics, Cornell University.

February 5, 2018:

JiaBei wins an Alzheimer's Association Research Fellowship!

January 30, 2018:

Jim presents invited seminar at the Dept. of Biochemistry & Molecular Biology, University of Chicago.

January 23, 2018:

Jim presents invited seminar at the Dept. of Neurology, University of Massachusetts Medical School.

January 19, 2018:

Lin wins award for outstanding presentation at the 3rd International Brainstorm Symposium at the Center for NeuroGenetics at the University of Florida.

January 19, 2018:

Jim presents invited seminar at the 3rd International Brainstorm Symposium at the Center for NeuroGenetics at the University of Florida.

January 18, 2018:

Lin presents poster at the 3rd International Brainstorm Symposium at the Center for NeuroGenetics at the University of Florida.

January 17, 2018:

Lin presents seminar at the 3rd International Brainstorm Symposium at the Center for NeuroGenetics at the University of Florida.

January 11, 2018:

Jim presents invited seminar at Penn CNDR.

2017

December 20, 2017:

Lin wins Target ALS Springboard Fellowship!

December 13, 2017:

Olivia wins ASCB Undergraduate Poster Competition!

December 11, 2017:

Jim presents invited seminar at the Dept. of Biochemistry & Molecular Biology at Thomas Jefferson University.

December 5, 2017:

Ed, Sanny, Ryan, and Saurabh present posters at the ASCB|EMBO 2017 Meeting in Philadelphia.

December 4, 2017:

Lin, JiaBei, Korrie, Zach, Eddie, and Olivia present posters at the ASCB|EMBO 2017 Meeting in Philadelphia.

December 1, 2017:

Jim presents invited seminar at the Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, FL.

November 28, 2017:

Jim presents invited seminar at the Donnelly Centre for Cellular and Biomolecular Research at the University of Toronto.

November 21, 2017:

Jim presents invited seminar at Sanofi.

November 20, 2017:

Jim presents invited seminar at Amgen.

November 10, 2017:

Korrie presents seminar at the Dr. George W. Raiziss 34th Annual Retreat at Skytop Lodge, Poconos. PA.

November 9, 2017:

Disaggregators repeat and defend Retreat Quizzo title!

November 4, 2017:

Jenny Ramirez presents seminar at the Annual Biomedical Research Conference for Minority Students (ABRCMS) in Phoenix, AZ and wins award!

October 31, 2017:

Jim presents invited seminar at the Dept. of Biological Sciences at the University of the Sciences.

October 26, 2017:

Jim presents invited seminar at MeiraGTx.

October 24, 2017:

Jim presents invited seminar at the Dept. of Biochemistry at the Albert Einstein College of Medicine.

October 18, 2017:

Jim presents invited seminar at the Dept. of Biochemistry at the University of Oxford.

October 16, 2017:

Jim presents invited seminar at The Francis Crick Institute.

October 11, 2017:

Jim presents invited seminar at the Fall Meeting of the International Graduate School in Molecular Medicine at Ulm University.

September 28, 2017:

Jim's News & Views published in EMBO J.

September 21, 2017:

Jim's Preview published in Cell.

September 19, 2017:

Zach is awarded a Ruth L. Kirschstein National Research Service Award (NRSA) from the National Institute of Neurological Disorders and Stroke (NINDS)!

September 15, 2017:

Lin and Ed Gomes present FRD!

August 14, 2017:

Olivia returns from screening sojourn in Gitler lab.

July 29, 2017:

Jenny presents seminar at the Leadership Alliance National Symposium in Hartford, CT.

July 26, 2017:

Jim presents invited seminar at the ALS Gordon Conference in Stowe, VT.

July 20, 2017:

Good luck to Meredith as she heads off to establish her own research program as an Assistant Professor in the Chemistry Department at Washington University in St. Louis!

July 10, 2017:

Good luck to Oscar as he heads off to pursue his Ph.D. in Molecular and Cellular Biology at Harvard University!

July 7, 2017:

Jim presents seminar at the Celebrate Susan Lindquist Symposium at the Whitehead Institute for Biomedical Research, MIT.

July 6, 2017:

Olivia wins poster prize at Penn CBI Retreat!

July 6, 2017:

Ryan presents seminar at Penn CBI Retreat.

June 29, 2017:

Great to host the Southworth lab at Penn for the day!

June 20, 2017:

Ryan selected as a 2017 predoctoral trainee for Dr. Josh Wand’s T32 Grant: Structural Biology and Molecular Biophysics Training Program

June 15, 2017:

Collaborative work with Dan Southworth at Univeristy of Michigan on cryo-EM structures of Hsp104 translocating substrate published in Science. See animation by Janet Iwasa, Penn press release and UM press release.

June 15, 2017:

R21 proposal funded by the National Institute of Neurological Disorders and Stroke (NINDS)!

June 14, 2017:

Meredith presents webinar at CReATe Virtual Journal Club.

June 13, 2017:

Jim presents seminar at FASEB Meeting 'Protein Aggregation in Health and Disease' in Steamboat Springs, CO.

May 31, 2017:

Alzforum covers Phase Transitions in Biology and Disease' meeting at VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium.

May 30, 2017:

BCBP pilot award funds our collaborative efforts with Ben Black's group.

May 16, 2017:

Jim presents seminar at Target ALS Annual Meeting at Biogen.

May 15, 2017:

Meredith presents seminar at Target ALS Annual Meeting at Biogen.

May 12, 2017:

Ryan passes his prelim!

May 12, 2017:

Olivia is elected to Phi Beta Kappa!

May 5, 2017:

Jim presents seminar at UCL Institute of Neurology.

May 5, 2017:

Jim joins the editorial board of Dis. Mod. Mech.

May 3, 2017:

Jim presents seminar at the 'Phase Transitions in Biology and Disease' meeting at VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium.

May 1, 2017:

Special collection, Neurodegeneration:From Models to Mechanisms to Therapies edited by Aaron Gitler and Jim published in Dis. Mod. Mech.

April 24, 2017:

Meredith presents poster and seminar at the ASBMB 2017 meeting in Chicago.

April 23, 2017:

Korrie and Zach present posters at the ASBMB 2017 meeting in Chicago.

April 15, 2017:

Oscar presents at the EAM Ivy League STAR conference.

April 8, 2017:

Olivia presents at the EAM Ivy League STAR conference.

April 5, 2017:

Collaborative work with Aaron Lucius accepted at Biochemistry.

April 4, 2017:

Jim featured in Biophysical Society Newsletter.

April 3, 2017:

Editorial with Aaron Gitler accepted at Dis. Mod. Mech.

March 31, 2017:

Alice's figure gets selected for the cover of Biochemical Journal!

March 30, 2017:

Jim presents seminar at the MPI-CBG in Dresden, Germany.

March 28, 2017:

Jim presents seminar at Molecular Tweezer Meeting at The Distalz Laboratory of Excellence, Lille, France.

March 27, 2017:

Jim presents seminar at International Workshop Inhibition of Protein-Protein Interactions in Alzheimer's Disease and Related Proteinopathies at The Distalz Laboratory of Excellence, Lille, France.

March 20, 2017:

Courtney is inducted to Pi Sigma Alpha!

March 16, 2017:

Ryan is accorded an Honorable Mention from the National Science Foundation.

March 9, 2017:

Jim presents seminar on collaborative work with Gitler, Taylor, and Pandey labs at The 17th Annual Packard Center Symposium.

February 24, 2017:

Lin presents to the Brangwynne lab at Princeton University.

February 20, 2017:

Eddie delivers seminar to The Department of Systems Pharmacology and Translational Therapeutics at Penn.

February 15, 2017:

Meredith's review accepted at Front. Neurosci.

February 13, 2017:

Korrie presents poster at the ADDF 11th Annual Drug Discovery for Neurodegeneration Conference.

February 9, 2017:

Alice's review accepted at Biochem. J.

January 26, 2017:

Korrie presents seminar at AstraZeneca Neuroscience.

January 26, 2017:

Jim's review accepted at Curr. Opin. Genet. Dev.

January 24, 2017:

Target ALS/ALS Finding a cure (ALSFAC) Industry-Led Consortium with AstraZeneca, Aaron Gitler, and Steve Finkbeiner recommended for funding!

January 20, 2017:

Zach and Korrie present at FRD!

January 19, 2017:

Collaborative work with Voula Mili accepted in JCB!

January 10, 2017:

Meredith and Zach win ASBMB 2017 Postdoctoral/Graduate Travel Awards.

2016

December 20, 2016:

Korrie wins ADDF 2017 Drug Discovery for Neurodegeneration Scholarship!

December 15, 2016:

Korrie presents seminar at AstraZeneca Neuroscience.

December 13, 2016:

Jim presents invited seminar at Dept. of Genetics and Development at Columbia University.

December 12, 2016:

Oscar wins Thermo Fisher Scientific Antibody Scholarship Award!

December 5, 2016:

Lin's review published in Cold Spring Harb. Persp. Med.

November 30 2016:

Obituary for Susan Lindquist by Jim and Aaron Gitler published in Nature. See also obituaries by: Jim in TiBS, Luke Whitesell and Sandro Santagata in Science, Elaine Fuchs in Cell , Rick Morimoto in NSMB, Brooke Bevis in JCB, Vivian Siegal in DMM, Tricia Serio in Nat. Chem. Biol., and Ulrich Hartl in EMBO J.

November 23, 2016:

Alex Fellows wins Bogue Research Fellowship from UCL to study in the Shorter Lab!

November 22, 2016:

Jim wins Department of Defense Therapeutic Idea Award!

November 18, 2016:

Jim presents seminar at the Dr. George W. Raiziss 33rd Annual Retreat at Skytop Lodge, Poconos. PA.

November 18, 2016:

Korrie wins poster prize at Dr. George W. Raiziss 33rd Annual Retreat!

November 17, 2016:

Disaggregators (Sanny, Christina, Meredith, Eddie, Ed, and Zach) triumph at Dr. George W. Raiziss 33rd Annual Retreat quizzo!

November 16, 2016:

Jim presents invited seminar at Dept. of Pharmacology and Cancer Biology at Duke University.

November 14, 2016:

Jim wins Sanofi Innovation Award!

November 10, 2016:

Jim presents invited seminar at Penn Chemistry Dept. Biological Chemistry Seminar Series.

November 7, 2016:

Alice defends her Ph.D. thesis!!!!

October 27, 2016:

Jim presents invited seminar at the Dept. of Neurosciences at Case Western Reserve University.

October 26, 2016:

Jim presents invited seminar at the Cleveland Clinic Lerner Research Institute.

October 19, 2016:

Jim presents invited seminar at Regeneron for the David J. Heslin Memorial Symposium.

October 17, 2016:

Olivia wins poster prize at the Penn Science and Engineering Undergraduate Research Poster Session!

October 11, 2016:

Lin presents seminar at RNP Discussion Group.

October 4, 2016:

Meredith and JiaBei present to the Southworth lab at the University of Michigan.

September 26, 2016:

Mike defends his Ph.D. thesis!!!!

September 13, 2016:

Jim presents invited seminar at Pfizer.

September 12, 2016:

Korrie and JiaBei present posters at the 17th International Conference on Alzheimer’s Drug Discovery in Jersey City!

August 24, 2016:

Jim presents seminar at the 252nd American Chemical Society National Meeting & Exposition in Philadelphia.

August 22, 2016:

Saurabh and JiaBei present posters at the 252nd American Chemical Society National Meeting & Exposition in Philadelphia.

August 22, 2016:

Lin wins an Alzheimer's Association Research Fellowship!

August 21, 2016:

Korrie, Lin, and Eddie present posters at the 252nd American Chemical Society National Meeting & Exposition in Philadelphia.

August 21, 2016:

Zach and Meredith present seminars at the 252nd American Chemical Society National Meeting & Exposition in Philadelphia.

August 2, 2016:

Korrie and JiaBei featured by the ADDF.

August 1, 2016:

Collaborative work with Dan Southworth at Univeristy of Michigan on cryo-EM structure of Hsp104 published in Nat. Struct. Mol. Biol. pdb emd See also News & Views by Steven Glynn and Peter Chien.

July 26, 2016:

Jim presents ALSA webinar.

July 19, 2016:

Korrie and JiaBei win an ADDF Young Investigator Scholarship to be received at the 17th International Conference on Alzheimer’s Drug Discovery!

June 14, 2016:

Eddie is reappointed to the Predoctoral Training Grant in Pharmacology!

June 14, 2016:

Alice presents seminar at RNP Discussion Group.

June 13, 2016:

Meredith presents invited seminar at the CBI Retreat at Bryn Mawr College.

June 8, 2016:

Jim presents invited seminar at Laboratory of Molecular Biology at NIH.

June 8, 2016:

Zach wins Chemistry-Biology Interface (CBI) Fellowship!

June 6, 2016:

Lin presents poster at the AFAR Scientific Conference in Santa Barbara.

May 31, 2016:

Eddie passes his prelim!

May 26, 2016:

Jim's News & Views on membraneless organelles appears in Nat. Chem.

May 20, 2016:

Jim serves as Honors Examiner at Swarthmore College.

May 18, 2016:

Rachel goes forth to pursue her M.D. at Harvard Medical School.

May 18, 2016:

Acacia goes forth to pursue her M.D./Ph.D. at USC/Caltech.

May 16, 2016:

R21 proposal funded by the National Institute of Neurological Disorders and Stroke (NINDS)!

May 12, 2016:

Jim's perspective is published at Mol. Biol. Cell.

May 10, 2016:

Ed and Rachel elected to Phi Beta Kappa.

May 2, 2016:

Zach's AudioSlides presentation "Prion-like domains as epigenetic regulators, scaffolds for subcellular organization, and drivers of neurodegenerative disease" is released.

April 25, 2016:

Zach passes his prelim!

April 25, 2016:

Jim presents invited seminar at The Vollum Institute/Junger's Center/OHSU.

April 18, 2016:

Lin's chapter for Cold Spring Harbor, Vol. 2, Prion Diseases is accepted.

April 14, 2016:

Meredith presents seminar at Target ALS Annual Meeting at Columbia University.

April 14, 2016:

Lin presents seminar at Target ALS Annual Meeting at Columbia University.

April 13, 2016:

Jim presents two seminars at Target ALS Annual Meeting at Columbia University.

April 8, 2016:

Korrie presents invited seminar at the 2016 Chemical Biophysics Mini-Symposium.

April 4, 2016:

Jim presents invited seminar at Calico.

March 30, 2016:

The Life Extension Foundation supports our work on Hsp104.

March 29, 2016:

Zach is accorded an Honorable Mention from the National Science Foundation.

March 14, 2016:

Aaron Gitler presents on our collaboration at The Packard Center Annual Symposium.

February 29, 2016:

Korrie's review is accepted at Frontiers Mol. Biosci.!

February 22, 2016:

The Packard Center for ALS Research at Johns Hopkins funds our collaborative efforts with Aaron Gitler's group.

February 20, 2016:

Zach's review is accepted at Brain Research!

February 3, 2016:

The Life Extension Foundation supports our work on Hsp104.

January 27, 2016:

Jim presents invited seminar at Keystone Symposium: Axons: From Cell Biology to Pathology.

January 15, 2016:

Meredith, Korrie, and Zach present at FRD.

January 8, 2016:

Mariana's paper is accepted and published at J. Biol. Chem.!

January 6, 2016:

Alice and Korrie present seminars at Target ALS Consortium Meeting at AstraZeneca Neuroscience.

January 6, 2016:

Jim presents seminar to AstraZeneca Neuroscience.

January 1, 2016:

Jim joins editorial board of the Biophysical Journal.

2015

December 22, 2015:

The Life Extension Foundation supports our work on Hsp104.

December 11, 2015:

Oscar is accepted into The University Scholars Program.

December 8, 2015:

Lin presents seminar at RNP Discussion Group.

December 1, 2015:

Liz's review is published at J. Mol. Biol.!

November 20, 2015:

Jim presents invited seminar at Department of Chemistry at the University of Alabama, Birmingham.

November 14, 2015:

Alzforum features our work on optimized protein disaggregases.

November 13, 2015:

Lin presents seminar at the Dr. George W. Raiziss 32nd Annual Retreat at Skytop Lodge, Poconos. PA.

October 19, 2015:

Jim presents invited seminar at Chaperones in Neurodegeneration Mini-Symposium at 2015 Meeting of the Society for Neuroscience.

October 15, 2015:

Lin's Preview is published in Molecular Cell!

October 15, 2015:

Jim presents invited seminar at 10th Brain Research Conference: RNA metabolism in neurological disease (official satellite to the 2015 Meeting of the Society for Neuroscience).

October 14, 2015:

Chaperones in neurodegeneration review with Iris Lindberg, Luke Wiseman, Fabrizio Chiti, Chad Dickey, and Pam McLean is published at J. Neurosci.

October 8, 2015:

Alice's Preview is published in Cell!

October 7, 2015:

Jim presents invited seminar at Penn CNDR Retreat.

October 5, 2015:

Meredith's paper is accepted and published at ACS Chem. Biol!

September 29, 2015:

Jim presents invited seminar at the CRC 1093 International Symposium on Supramolecular Chemistry on Proteins at the University of Duisburg‐Essen, Essen, Germany.

September 22, 2015:

Jim presents invited seminar at Department of Neuroscience at Thomas Jefferson University.

September 22, 2015:

Jim invited to join editorial board of the Biophysical Journal

September 16, 2015:

Jim presents invited seminar at The Huck Institutes of the Life Sciences at Penn State University.

August 28, 2015:

Laura and Rebecca's paper is published at Biology Open!

August 18, 2015:

Laura's collaborative paper with the Münch lab is published at eLife! See also eLife digest, eLife press release, Drug Target Review, IFLScience, Wired , WHYY Newsworks & Penn press release.

August 10, 2015:

Good luck to Mariana as she goes on to set up her own research program as an Assistant Professor in the Chemistry Department at Brooklyn College!

August 6, 2015:

Laura's paper is published at Chemistry & Biology! See also preview by Ram Krishnan and Penn press release.

July 30, 2015:

Jim presents invited seminar at the Whitehead Institute for Biomedical Research at MIT.

July 25, 2015:

Laura and Rebecca's paper is accepted at Biology Open!

July 21, 2015:

Meredith's proposal to be tested by the Target ALS in vivo target validation core!

July 20, 2015:

Laura's collaborative paper with the Münch lab is accepted at eLife!

July 9, 2015:

Laura's paper is accepted at Chemistry & Biology!

July 6, 2015:

Jim presents invited seminar at Gordon Conference: 'Stress Proteins in Growth, Development and Disease'

June 24, 2015:

Jim presents seminar at Abramson Cancer Center Sarcoma meeting.

June 18, 2015:

Eddie is appointed to the Predoctoral Training Grant in Pharmacology!

May 19, 2015:

Meredith presents seminar at RNP Discussion Group.

May 15, 2015:

Korrie and Alice present at FRD.

May 1, 2015:

Korrie passes her prelim!

April 29, 2015:

Jim presents invited seminar at Dept. of Chemical and Biological Engineering at Princeton University.

April 21, 2015:

MDA features our work on Hsp104.

April 19, 2015:

Megan publishes video: Characterizing Hyperactive Mutations of Hsp104 in terms of Protein Structure.

April 16, 2015:

Meredith presents seminar at Target ALS Annual Meeting at Columbia University.

April 16, 2015:

Alice presents seminar at Target ALS Annual Meeting at Columbia University.

April 15, 2015:

Jim presents seminar at Target ALS Annual Meeting at Columbia University.

April 9, 2015:

Jim presents invited seminar at the Huffington Center on Aging & Department of Biochemistry and Molecular Biology at Baylor College of Medicine.

April 7, 2015:

The Life Extension Foundation supports our work on Hsp104.

April 3, 2015:

Jim presents invited seminar at the Motor Neuron Center at Columbia University.

March 31, 2015:

Zach is accorded an Honorable Mention from the National Science Foundation.

March 26, 2015:

Jim presents invited seminar at Dept. of Pharmacology & Molecular Sciences at Johns Hopkins University.

March 19, 2015:

Jim presents invited seminar at Dept. of Biology at The University of Virginia.

March 18, 2015:

Paper with Münch lab accepted at Cell Reports!

March 10, 2015:

Jim presents invited seminar at Dept. of Biological Chemistry at The University of Michigan.

March 5, 2015:

Oscar is selected for a summer internship via a German Academic Exchange Service (DAAD) scholarship!

February 26, 2015:

Jim presents seminar on collaborative work with Gitler, Taylor, and Pandey labs at The Packard Center Annual Symposium.

February 12, 2015:

Meredith's review is accepted at Prion!

January 30, 2015:

Mariana's NINDS Advanced Postdoctoral Career Transition Award to Promote Diversity in Neuroscience Research (K22) is approved for funding!!!

January 22, 2015:

Elizabeth's paper published at Molecular Cell!!! See Penn press release.

January 13, 2015:

Alice presents seminar at RNP Discussion Group.