2025

July 3, 2025:

Katie is selected as an award recipient for the 2025 NIH Outstanding Scholars in Neuroscience Award Program (OSNAP)!

June 27, 2025:

Jim is awarded an Penn Institute on Aging Alzheimer’s Disease Therapeutics Accelerator Award!

June 18, 2025:

Collaborative work with Luc Dupuis on FUS mislocalization driving cognitive and behavioral impairment in ALS preprinted on medRxiv!

May 30, 2025:

Lina presents poster at RNA Society Annual Meeting in San Diego, CA.

May 22, 2025:

Jim presents seminar at The Kissick Family Foundation FTD Funded Investigators Meeting in San Francisco.

May 19, 2025:

Congratulations to our graduating Penn seniors, Vasu and Ken!

May 19, 2025:

Miriam presents seminar at the Neuro4D conference in Mainz, Germany.

May 13, 2025:

Miriam presents flash talk and poster at the 'Biomolecular condensates: From fundamental principles to applictions in health and biotech' conference at The Carlsberg Academy, Copenhagen, Denmark.

May 10, 2025:

Eddie's paper on chaperone safeguards buffering TDP-43 toxicity preprinted on bioRxiv!

May 5, 2025:

Zoe passes her prelim!!!

May 2, 2025:

Abby presents her Capstone Seminar for the Master in Chemical Sciences Progam.

May 1, 2025:

Jim is awarded a Department of Defense ALSRP Therapeutic Idea Award!

April 30, 2025:

Miriam is selected as a recipient of the 2025 ALS Scholars in Therapeutics Award from The Sean M. Healey & AMG Center for ALS, ALS Finding a Cure, & FightMND!

April 25, 2025:

Jim presents Keynote at the 23rd Annual Data and Dine Postdoctoral Research Symposium at Penn State College of Medicine.

April 22, 2025:

Jim presents invited seminar at the Dept. of Cell Biology at UTSW.

April 21, 2025:

Katie wins the 2025 Saul Winegrad Award for outstanding dissertation by a NGG student!

April 15, 2025:

Zarin presents lightning talk and poster at the 2025 Annual Meeting of the American Society for Biochemistry and Molecular Biology in Chicago.

April 15, 2025:

Penn Institute on Aging spotlights Jim.

April 12, 2025:

Zarin presents seminar at the 2025 Annual Meeting of the American Society for Biochemistry and Molecular Biology in Chicago.

April 4, 2025:

Zarin and JiaBei present at FRD!

March 21, 2025:

Collaborative work with György Hajnóczky on Skd3 regulating mitochondrial calcium signalling and dynamics published in Nat. Comm.!

March 10, 2025:

Katie defends her Ph.D. thesis!!!!

March 5, 2025:

Jim presents seminar at the 25th Annual Packard Center Symposium.

March 3, 2025:

Eddie presents poster at the 25th Annual Packard Center Symposium.

March 2, 2025:

Katie presents poster at the 25th Annual Packard Center Symposium.

February 19, 2025:

Miriam presents poster at BPS2025 in Los Angeles, CA & invited seminar at UCLA.

February 12, 2025:

Target ALS features Mari and Hana's paper.

January 20, 2025:

Jim visits the Gitler lab at Stanford.

January 17, 2025:

Jim presents invited seminar at the 15th Annual ALS Network Research Summit in San Francisco, CA.

January 15, 2025:

Mari and Hana's paper on opposing roles for p38α-mediated phosphorylation and PRMT1-mediated arginine methylation in driving TDP-43 proteinopathy published in Cell Rep.!

January 2, 2025:

Collaborative work with Lin Guo on engineering Kapβ2 against c9DPRs published in Commun. Biol.!

2024

December 15, 2024:

Katie's paper on short RNA chaperones for TDP-43 preprinted on bioRxiv!

December 12, 2024:

JiaBei's paper on design principles to tailor Hsp104 therapeutics published in Cell Rep.!

December 6, 2024:

Raju wins poster prize at the Dr. George W. Raiziss 40th Annual Retreat at Skytop Lodge, Poconos. PA.

December 6, 2024:

Zoe wins poster prize at the Dr. George W. Raiziss 40th Annual Retreat at Skytop Lodge, Poconos. PA.

December 6, 2024:

Jim delivers Keynote at the Colorado Proteinopathy Symposium 2024 at the Knoebel Institute for Healthy Aging, University of Denver.

November 18, 2024:

ALS Canada-Brain Canada Discovery Grant with Maria DeRosa at Carleton University recommended for funding!

November 7, 2024:

JiaBei presents seminar at Dr. George W. Raiziss Rounds Seminar Series.

October 3, 2024:

Collaborative work with Anita Manogaran on Sup35 prion processing by enhanced Hsp104 variants published in PLoS Genet.!

October 2, 2024:

JiaBei delivers seminar at the Philadelphia Symposium for Postdoctoral Initiatives in Neuroscience Excellence!

September 25, 2024:

The Kissick Family Foundation and Milken Institute funds our collaborative work with Chris Donnelly and Bob Kalb on FTD. See Milken Institute press release.

September 23, 2024:

The Packard Center for ALS Research at Johns Hopkins funds our work on TDP-43.

September 10, 2024:

Katie presents seminar at RNP Discussion Group.

September 9, 2024:

JiaBei selected as a Philadelphia Symposium for Postdoctoral Initiatives in Neuroscience Excellence (P-SPINE) Fellow!

August 20, 2024:

Miriam wins a Mildred Cohn Distinguished Postdoctoral Award!

August 15, 2024:

JiaBei wins a Biochemistry & Biophysics Department Research Excellence and Resilience Award!

August 5, 2024:

Jim wins Zenith Fellows Award from the Alzheimer's Association!

July 26-28, 2024:

Ishareet presents poster at The Leadership Alliance National Symposium 2024 in Hartford, CT.

July 25-27, 2024:

Miriam presents poster at the Live Like Lou Foundation’s invitation-only biennial ALS Research Symposium at the University of Michigan.

July 18, 2024:

Miriam wins an Alzheimer's Association Reseach Fellowship!

June 24, 2024:

Lina presents poster at the IRACDA 2024 Conference in Chapel Hill, NC.

June 11, 2024:

Collaborative work with Sandrine Da Cruz on FUS prionoids published in Mol. Neurodegen.!

June 3, 2024:

Collaborative work with Sandrine Da Cruz on FUS prionoids preprinted at bioRxiv!

May 30, 2024:

Katie presents poster at RNA Society Annual Meeting in Edinburgh, Scotland.

May 21, 2024:

Jim serves as Honors Examiner at Swarthmore College.

May 20, 2024:

Congratulations to our graduating Penn senior, Albert Wang!!

May 15, 2024:

Miriam presents poster at the EMBO|EMBL symposium on cellular mechanisms driven by phase separation in Heidelberg, Germany.

April 28, 2024:

JiaBei's paper on design principles to tailor Hsp104 therapeutics preprinted on bioRxiv!

April 26, 2024:

Zarin presents poster at 'Protein Homeostasis in Health and Disease', Cold Spring Harbor Meeting.

April 25, 2024:

Eddie presents poster at 'Protein Homeostasis in Health and Disease', Cold Spring Harbor Meeting.

April 2, 2024:

Atomwise Aims Program paper published in Sci. Rep. See Atomwise press release.

March 19, 2024:

Ken wins Career Services Summer Funding Award!

March 10, 2024:

Katie presents poster at the 24th Annual Packard Center Symposium.

February 14, 2024:

Katie presents poster at BPS2024 in Philadelphia.

February 11, 2024:

JiaBei, Miriam, and Zarin present posters at BPS2024 in Philadelphia.

February 10, 2024:

Alondra presents poster at BPS2024 in Philadelphia.

February 10, 2024:

JiaBei presents seminar at BPS2024 in Philadelphia.

February 5, 2024:

Collaborative work with Ophir Shalem's group on SRRD and aggresome assembly published in PLoS Genet.

January 25, 2024:

ITMAT funds our Pilot Grant with Lijun Zhou in the Transdisciplinary Awards Program in Translational Medicine and Therapeutics!

January 22, 2024:

Miriam's review with Bilal and Courtney from the Rossoll lab on nuclear-import receptors as gatekeepers for pathological phase transitions published in Mol. Neurodegen.

January 19, 2024:

Ryan's Skd3 review published in special issue of Isr. J. Chem. to honor Jeff Kelly upon winning the Wolf Prize in Chemistry! Congratulations Jeff!!

January 18, 2024:

Lina's spotlight published in Cell Chem. Biol.

January 12, 2024:

Eddie Chuang's paper on small-molecule stimulators of the human Hsp70-disaggregase system preprinted on bioRxiv!

2023

December 1, 2023:

Raju wins first prize for biophysics poster at the Dr. George W. Raiziss 39th Annual Retreat at Skytop Lodge, Poconos. PA.

December 1, 2023:

JiaBei wins second prize for biophysics poster at the Dr. George W. Raiziss 39th Annual Retreat at Skytop Lodge, Poconos. PA.

December 1, 2023:

Eddie delivers invited seminar at the Dr. George W. Raiziss 39th Annual Retreat at Skytop Lodge, Poconos. PA.

November 14, 2023:

Katie presents invited seminar at the Society for Neuroscience Annual Meeting.

November 13, 2023:

Jim presents invited seminar at the RNA Medicine Program at Stanford University.

November 6, 2023:

Jim presents invited seminar at the 13th Annual Les Turner ALS Symposium at Feinberg School of Medicine at Northwestern University.

November 2, 2023:

Katie presents invited seminar at Confluence Therapeutics.

October 10, 2023:

MNDA highlights our work on RNA oligonucleotides that reverse deleterious phase transitions of TDP-43.

October 6, 2023:

Jim delivers The James A. Aleveras Formal Research Seminar at the Buck Institute.

October 4, 2023:

Raju, JiaBei, Zarin, and Zoe present seminars at our super group meeting with Southworth and Jain labs at UCSF.

October 3, 2023:

Jim presents 'The Basic Science Seminar:  A Celebration of Audacious Fundamental Research' at UCSF.

September 6, 2023:

Jim presents invited seminar at the Arturo Falaschi Conference “1st biennial conference on TDP-43 function and dysfunction in disease” in Trieste, Italy.

September 5, 2023:

Collaborative work with Lin Guo and Chris Donnelly on RNA oligonucleotides that reverse deleterious phase transitions of FUS and TDP-43 preprinted at bioRxiv!

August 24, 2023:

Korrie's paper on tuning Hsp104 specificity to selectively detoxify alpha-synuclein published in Mol. Cell!

August 23, 2023:

Lina wins a Ruth L. Kirschstein Postdoctoral National Research Service Award from NINDS!

August 18, 2023:

JiaBei wins a Mildred Cohn Distinguished Postdoctoral Award!

July 29, 2023:

Brennen presents seminar at The Leadership Alliance National Symposium 2023 in Hartford, CT.

July 26, 2023:

Chem. Rev. issue on phase separation published with editorial from Jim and Sua Myong.

July 20, 2023:

Collaborative work with Lin Guo, Marcus Fändrich, and Kartikay Sharma on hnRNPA1 fibril structure published in J. Mol. Biol.

July 12, 2023:

Collaborative work with Jernej Ule and Adrian Isaacs on genome-wide RNA binding analysis of C9orf72 poly(PR) dipeptides published in Life Sci. Alliance.

July 3, 2023:

Jim presents invited seminar at the Stress Proteins GRC at Tuscany Il Ciocco, Italy.

June 30, 2023:

Good luck to Sylvanne as she heads off to Carnegie Mellon University to pursue her MSBA!

June 26, 2023:

Lina presents poster at the IRACDA 2023 Conference in San Antonio, TX.

June 16, 2023:

Zarin wins poster award at the Proteins GRC at Holderness School, NH!

June 15, 2023:

Zarin presents flash talk and poster at the Proteins GRC at Holderness School, NH.

June 14, 2023:

Jim presents invited seminar at the Proteins GRC at Holderness School, NH.

June 14, 2023:

Zarin presents poster at the Proteins GRC at Holderness School, NH.

June 9, 2023:

Good luck to Shariq has he heads on to the BRIDGE program NYIT to pursue an M.S. and D.O.!

May 24, 2023:

Hana becomes the next Johnson Foundation Fellow!

May 15, 2023:

Congratulations to our graduating Penn senior, Ashleigh Smirnov!!

May 12, 2023:

Congratulations to Zoe Chen who graduated with her Masters in Biotechnology from Penn today!

May 9, 2023:

Katie presents seminar at RNP Discussion Group.

April 28, 2023:

Review with Kevin Rhine, Hana Odeh, and Sua Myong on regulation of biomolecular condensates by poly(ADP-ribose) published in Chem. Rev.

April 13, 2023:

Alondra presents seminar at the Penn FERBS symposium

April 11, 2023:

Jim presents invited seminar at the Department of Molecular and Cellular Biology, University of Arizona.

March 31, 2023:

Collaborative work with Elke Bogaert and Bart Dermaut at Ghent University on C-terminal frameshift variant of TDP-43 linked to rimmed vacuole myopathy published in Acta. Neuropathol.

March 28, 2023:

Jim presents invited seminar in the 'Disordered protein in diseases' symposium at the ASBMB Annual Meeting DiscoverBMB2023 in Seattle, WA.

March 17, 2023:

Katie's review on repetitive elements in aging and neurodegeneration is published in Trends Genet.!

March 15, 2023:

Jim presents invited seminar at the Department of Biological Sciences, Carnegie Mellon University.

March 10, 2023:

Katie and Zarin present at FRD!

March 3, 2023:

Eddie wins an NIH Pathway to Independence Award (K99/R00) from the National Institute on Aging (NIA)!!

February 27, 2023:

Katie and Miriam present posters at the 23rd Annual Packard Center Symposium.

February 27, 2023:

Jim presents invited seminar at the 23rd Annual Packard Center Symposium.

February 3, 2023:

Jim presents invited seminar to the Biology Dept. at Swarthmore College

January 20, 2023:

Review article that captures the discussion at the Telluride science research center phase separation workshop published in J. Mol. Biol.

January 17, 2023:

Miriam featured by ALSA: Early Career ALS Researchers Receive Vital Support through The ALS Association’s Milton Safenowitz Postdoctoral Fellowship

January 17, 2023:

Charlotte's paper on molecular determinants of Karyopherin-β2 chaperone and disaggregation activity published in J. Biol. Chem.

2022

December 22, 2022:

Good luck to Charlotte as she heads off to Johns Hopkins to pursue her post-doc with Jeff Rothstein.

December 15, 2022:

Charlotte's paper on molecular determinants of Karyopherin-β2 chaperone and disaggregation activity published in press at J. Biol. Chem.

December 8, 2022:

Collaborative work with Wilfried Rossoll at Mayo Clinic on nuclear-import receptors and TDP-43 proteinopathy published in Mol. Neurodegen.

December 2, 2022:

Miriam wins best postdoc poster prize at the Dr. George W. Raiziss 38th Annual Retreat at Skytop Lodge, Poconos. PA.

December 2, 2022:

Katie wins best biochemistry poster prize (Kathryn M. Ferguson Award) at the Dr. George W. Raiziss 38th Annual Retreat at Skytop Lodge, Poconos. PA.

December 1, 2022:

Jim presents seminar at the Dr. George W. Raiziss 38th Annual Retreat at Skytop Lodge, Poconos. PA.

November 3, 2022:

Jim presents invited seminar at the Pennsylvania Biotechnology Center, Blumberg Institute, and Fox Chase Chemical Diversity Center in Doylestown, PA.

October 26, 2022:

Charlotte defends her Ph.D. thesis!!!!

October 11, 2022:

Collaborative work with Jernej Ule and Adrian Isaacs on genome-wide RNA binding analysis of C9orf72 poly(PR) dipeptides preprinted at BioRxiv.

September 27, 2022:

Ryan and Alex's paper on Skd3 structure and mechanism with Dan Southworth published in Cell Reports!

September 16, 2022:

Jim presents invited seminar at the Department of Molecular, Cellular, and Developmental Biology at the University of Michigan.

September 15, 2022:

Charlotte's paper on molecular determinants of Karyopherin-β2 chaperone and disaggregation activity prepinted at BioRxiv.

September 6, 2022:

Collaborative work with Schrader, Sanchez-Garcia, and Münch labs on viral disruption by advanced molecular tweezers published in JACS Au!

September 1, 2022:

Katie is awarded a Ruth L. Kirschstein National Research Service Award (NRSA) from the National Institute of Neurological Disorders and Stroke (NINDS)!

August 19, 2022:

Jim presents invited seminar at Robert Packard Center, Pederson Brain Science Institute at Johns Hopkins University.

August 18, 2022:

R21 proposal funded by the National Institute of Aging (NIA)!

July 29, 2022:

Miriam wins a Milton Safenowitz Post-Doctoral Fellowship from the ALS Association!

July 28, 2022:

Jim presents invited seminar at the Molecular and Cellular Neurobiology Gordon Research Conference at Ventura Beach, CA.

July 20, 2022:

Zarin presents invited seminar at the Department of Biochemistry and Molecular Biology, University of Dhaka, Bangladesh.

July 17, 2022:

Jim presents invited seminar at the Whitehead Institute for Biomedical Research for Sue-palooza 2022.

July 8, 2022:

Good luck to Erica as she heads off to be a visiting assistant professor at Ursinus College.

July 1, 2022:

Good luck to Jack as he heads off to MIT to pursue his Ph.D.

June 16, 2022:

Miriam earns post-doctoral fellowship from Swiss National Science Foundation (SNSF)!

June 15, 2022:

Good luck to Ben as he heads off to Thomas Jefferson University to pursue his M.D.

May 26, 2022:

JiaBei presents seminar at Dr. George W. Raiziss Rounds Seminar Series.

May 18, 2022:

Collaborative work with Yale Goldman and Kathy Liu on DDX3X/Y phase separation published in Mol. Cell.

May 17, 2022:

Collaborative work with Leeanne McGurk and May Khanna on HspA5 and TDP-43 published in Scientific Reports.

May 16, 2022:

Jim presents invited seminar at Dept. of Molecular Biophysics and Biochemistry at Yale University.

May 16, 2022:

Congratulations to our graduating Penn seniors Max Tjauw and Sylvanne Braganza!

May 12, 2022:

Collaborative work with Iris Lindberg on proSAAS and TDP-43 published in ACS Chem Neurosci.

May 11, 2022:

Zarin passes her prelim!!!

May 9, 2022:

Jim presents invited seminar at the 'Molecular Bases of Proteinopathies' zoominar series at the University of Michigan.

May 4, 2022:

Congratulations to our graduating Temple senior George Padilla!

May 3, 2022:

Jim presents seminar at Target ALS Annual Meeting as part of consortium with Chris Donnelly and Merck.

April 29, 2022:

Jim co-chairs session and presents invited seminar at the Cold Spring Harbor Protein Homeostasis Meeting.

April 28, 2022:

Collaborative work with Paul Taylor and Carsten Bönnemann on hnRNPA2 variants causing early-onset oculopharyngeal muscular dystrophy published in Nat. Comm.

April 26, 2022:

Jim presents invited seminar at the Condensate Colloquium Series.

April 25, 2022:

Jim presents Grand Rounds at the Penn Alzheimer's Disease Research Center.

April 22, 2022:

Ryan wins the 2022 Saul Winegrad Award for best dissertation by a PGG student!

April 14, 2022:

Katie's Preview on TMEM106B(120-254) fibrils is published in Cell.

April 5, 2022:

Katie wins Penn Prize for Teaching Excellence by Graduate Students!

April 4, 2022:

Charlotte, Katie, and Jack present posters at the 2022 Annual ASBMB Meeting in Philadelphia.

April 4, 2022:

Jack, Alexis, and Lauren win National Science Foundation Graduate Research Fellowships!

April 3, 2022:

Charlotte presents seminar at the 2022 Annual ASBMB Meeting in Philadelphia.

April 3, 2022:

Zarin, Ben, George, Evan, and Erica present posters at the 2022 Annual ASBMB Meeting in Philadelphia.

April 2, 2022:

JiaBei presents poster at the 2022 Annual ASBMB Meeting in Philadelphia.

March 31, 2022:

JiaBei's review with Aaron Lucius on AAA+ protein mechanisms is published in Biochem. Soc. Trans.

March 23, 2022:

Jim presents invited seminar at Telluride Science Research Center Workshop on phase separation in biology and disease.

March 22, 2022:

Lina is accorded an Honorable Mention from the Ford Foundation.

March 1, 2022:

Jim presents invited seminar at the 22nd Annual Packard Center Symposium.

February 28, 2022:

Charlotte and Katie present posters at the 22nd Annual Packard Center Symposium.

February 24, 2022:

The Packard Center for ALS Research at Johns Hopkins funds our work on TDP-43.

February 23, 2022:

Collaborative work with Aaron Gitler, Len Petrucelli, and Sua Myong et al. on TDP-43 repressing cryptic exon inclusion in UNC13A published in Nature. See also accompanying study from Ward & Fratta labs, and also News & Views and STAT news article.

February 21, 2022:

Charlotte presents seminar at 66th Biophysical Society Annual Meeting in San Francisco.

February 18, 2022:

Collaborative work with Anthony Leung and Sua Myong on FUS-PAR interactions published in Mol. Cell.

February 17, 2022:

Ryan and Alex's paper on Skd3 structure and mechanism with Dan Southworth posted on BioRxiv

February 8, 2022:

Jack presents seminar at RNP Discussion Group.

February 3, 2022:

Collaborative work with Daniel Link on Skd3 (human ClpB) variants causing severe congenital neutropenia featured in a Commentary in Blood.

January 5, 2022:

Hana and Charlotte get the cover of J. Mol. Biol.

2021

December 8, 2021:

Hana's News & Views on TDP-43 fibril structure published in Nature.

December 8, 2021:

Collaborative work with Leeanne McGurk and May Khanna on HspA5 and TDP-43 preprinted at Research Square.

December 2, 2021:

Hana wins the Ruth Keris Award for Departmental and Graduate Group Service!

December 2, 2021:

JiaBei wins best postdoc poster prize at the Dr. George W. Raiziss 37th Annual Retreat at Penn Museum!

December 2, 2021:

Charlotte presents seminar at the Dr. George W. Raiziss 37th Annual Retreat at Penn Museum.

November 12, 2021:

Jim presents seminar at the Penn IOA/CNDR Retreat.

November 10, 2021:

Jim presents seminar at the Symposium on Structural Biology 2021 (SimBE 2021).

November 8, 2021:

Hana presents seminar at the Second Annual Diversity and Science Symposium.

November 4, 2021:

Ryan presents seminar at MitoCare.

November 3, 2021:

Jim presents seminar at the Cell Symposium on Biological Assemblies: Phase transitions and more.

November 2, 2021:

Charlotte presents poster at the Cell Symposium on Biological Assemblies: Phase transitions and more.

October 31, 2021:

Collaborative work with Marmorstien lab on N-alpha-acetylation of Huntingtin protein published in J. Biol. Chem.

October 29, 2021:

Good luck to Ryan as he heads off to NIH to pursue his post-doc with Richard Youle.

October 20, 2021:

Ryan defends his Ph.D. thesis!!!!

October 12, 2021:

Katie presents seminar at RNP Discussion Group.

October 8, 2021:

Jim presents invited seminar at The Department of Chemistry at Villanova University.

October 5, 2021:

Jim presents invited seminar in the Cellular and Protein Homeostasis Webinar Series hosted by Paolo De Los Rios, Pierre Goloubinoff, Nadinath Nillegoda, and Alessandro Barducci.

September 24, 2021:

Ryan presents seminar at mitochondrial homeostasis and human disease EMBO workshop in Girona, Spain.

September 23, 2021:

Jim presents invited virtual seminar at the Molecular & Cell Biology & Genetics Seminar Series at Drexel College of Medicine.

September 15, 2021:

Lina starts her PENN-PORT post-doctoral fellowship in the lab.

September 10, 2021:

Jim presents invited virtual seminar at the Second UCL Queen Square Motor Neuron Disease Centre International Symposium.

August 31, 2021:

Good luck to April as she heads off to Lacerta Therapeutics.

August 28, 2021:

Hana and Charlotte's review on nuclear-import receptors is published in J. Mol. Biol.

August 25, 2021:

Hana wins an Alzheimer’s Association Research Fellowship (AARF)!

August 18, 2021:

Collaborative work with Xiaolu Yang on DAXX as a new type of protein-folding enabler published in Nature. See Penn press release.

August 12, 2021:

Jim presents virtual seminar for RBNC Therapeutics (Neumora).

August 10, 2021:

Collaborative work with Martina Hallegger and Jernej Ule on TDP-43 condensation and regulation published in Cell.

August 4, 2021:

Collaborative work with AstraZeneca, Steve Finkbeiner, and Aaron Gitler on p38alpha and TDP-43 preprinted at BioRxiv.

July 22, 2021:

Collaborative work with Paul Taylor and Jonathan Baets on hnRNPA1 variants in hereditary motor neuropathy, ALS, and myopathy published in JCI Insight.

July 20, 2021:

Collaborative work with Anthony Leung and Sua Myong on FUS-PAR interactions preprinted at Cell Press Sneak Peek.

July 2, 2021:

Katie selected as a 2021 predoctoral trainee for the Structural Biology & Molecular Biophysics (SBMB) training program.

June 25, 2021:

Jim presents virtual seminar at FASEB Meeting 'Protein Aggregation Conference: Function, Dysfunction, and Disease'.

June 15, 2021:

Charlotte, Alexis, and Lauren's review of higher-order organization of biomolecular condensates published in Open Biology.

June 11, 2021:

Collaborative work with Daniel Link on Skd3 (human ClpB) variants causing severe congenital neutropenia published in Blood.

June 10, 2021:

Jim presents invited seminar at the Middle Atlantic Regional Meeting of the American Chemical Society 2021.

June 8, 2021:

Hana presents seminar at RNP Discussion Group.

June 2, 2021:

Onsite research of Shorter lab ramps up in Phase 3 reopening (100% occupancy).

May 28, 2021:

Good luck to Allan as he heads off to pursue his M.D. at The University of Minnesota.

May 19, 2021:

Erica's Preview published in Neuron.

May 18, 2021:

Katie passes her prelim!!!

May 17, 2021:

Congratulations to Andrew Lam on winning a Penn Alumni Student Award of Merit!

May 17, 2021:

Congratulations to our graduating Penn seniors Sarah Khan, Baotram Nguyen, Andrew Lam, and Kenneth Li!

May 10, 2021:

Jim presents invited virtual seminar at SickKids at The University of Toronto.

May 4, 2021:

Jim presents seminar at virtual Target ALS Annual Meeting as part of consortium with Chris Donnelly and Merck.

May 4, 2021:

Charlotte's review published in Dis. Mod. Mech.

April 27, 2021:

Zach wins the 2021 Saul Winegrad Award for best dissertation by a BMB student!

April 26, 2021:

Bede presents invited virtual seminar at the ASBMB Protein Interest Group.

April 23, 2021:

Jim presents invited virtual seminar at the Advances in Biomedical Research Seminar Series at The University of Ottawa.

April 16, 2021:

Collaborative work with Paul Taylor and Carsten Bönnemann on hnRNPA2 variants in early-onset oculopharyngeal muscular dystrophy preprinted in MedRxiv.

April 14, 2021:

Jim serves as Sterling Drug Visiting Lecturer virtually at the Department of Pharmacology & Experimental Therapeutics at Boston University.

April 5, 2021:

Good luck to Bede as he heads off to Dewpoint Therapeutics.

March 19, 2021:

Bede and Eddie present seminar at the virtual Group Meeting with May Khanna's lab!

March 17, 2021:

Bede and Jack present seminars at the virtual Gitler-Myong-Shorter-Ha (GMSH) Meeting!

March 16, 2021:

Eddie, Ryan, and Charlotte present seminars at the virtual Gitler-Myong-Shorter-Ha (GMSH) Meeting!

March 11, 2021:

Jim delivers virtual keynote seminar at the CReATe Consortium Annual Meeting.

March 8, 2021:

Jim presents invited virtual seminar at the 21st Annual Packard Center Symposium.

March 8, 2021:

Bede presents invited virtual seminar at Syracuse University Biology Department.

March 4, 2021:

Jim presents invited virtual seminar at the Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences.

February 26, 2021:

Hana presents invited virtual seminar at the B&B/BMB Mini-Symposium.

February 23, 2021:

Jim presents invited virtual seminar at the Department of Biochemistry at West Virginia University.

February 16, 2021:

Jim presents invited virtual seminar at Biophysics of Amyloid Formation Meeting at Ulm University.

February 5, 2021:

April's review published in BBA.

February 4, 2021:

Charlotte's spotlight published in Trends Genet.

February 3, 2021:

Collaborative work with Paul Taylor and Jonathan Baets on hnRNPA1 variants in hereditary motor neuropathy, ALS, and myopathy preprinted in MedRxiv.

January 11, 2021:

Bede and Linda's review on FUS and TDP-43 phases published in Trends Biochem. Sci.

2020

December 30, 2020:

Bede's review on biochemical timekeeping via reentrant phase transitions published in J. Mol. Biol.

December 22, 2020:

Collaborative work with Dorothee Dormann on nuclear-import receptors and c9DPRs published in Cell Rep.

December 16, 2020:

Jim presents invited virtual seminar at Faze Medicines.

December 15, 2020:

Zach's paper on therapeutic genetic variation in Hsp104 homologs published in eLife

December 11, 2020:

Hana's artwork featured on the cover of Emerg. Top. Life Sci.

December 9, 2020:

Jim presents invited virtual seminar at Institute for Quantitative Biomedicine at Rutgers University.

December 5, 2020:

Ryan's methods paper published in Bio-Protocol

December 4, 2020:

Hana presents invited virtual seminar at Cold Spring Harbor Laboratory Meeting: Neurodegenerative Diseases: Biology & Therapeutics.

December 1, 2020:

Collaborative work with Xiaolu Yang on TRIM disaggregases published in Cell Rep.!

November 13, 2020:

Ryan presents invited virtual seminar at Cold Spring Harbor Laboratory Meeting: Protein Homeostasis in Health and Disease.

November 13, 2020:

Jim presents invited seminar at the RNA at the Bench and Bedside II Virtual Conference.

November 9, 2020:

Shariq presents poster at the Annual Biomedical Research Conference for Minority Students (ABRCMS) 2020.

November 6, 2020:

Collaborative work with Sua Myong on FUS variants published in Mol. Cell!

October 26, 2020:

Hana's renews her AstraZeneca post-doctoral fellowship.

October 15, 2020:

Hana presents virtual seminar for AstraZeneca Neuroscience.

October 13, 2020:

Jim presents invited virtual seminar for Florida Atlantic University Brain Institute.

October 13, 2020:

Bede presents seminar at RNP Discussion Group.

September 19, 2020:

Charlotte and Ryan present at FRD!

September 14, 2020:

Collaborative work with Schrader, Sanchez-Garcia, and Münch labs on viral disruption by molecular tweezers published in JACS! See also, Chembites coverage.

September 14, 2020:

Erica starts her PENN-PORT post-doctoral fellowship in the lab.

September 4, 2020:

Good luck to Zach as he heads off to NIH to pursue his post-doc with Priyanka Narayan.

September 2, 2020:

Hana's co-first author paper on collaborative work with Yong-Jie Zhang and Len Petrucelli on poly(GR) stimulating TDP-43 aggregation out in Sci. Trans. Med.! See also, Penn press release, Alzforum coverage, Fierce biotech story, and Packard Center.

September 1, 2020:

Good luck to Eddie Chuang as he heads off to Rutgers to pursue his post-doc with Monica Driscoll in the INSPIRE IRACDA program.

August 26, 2020:

Jim presents invited virtual seminar for the Northwestern, Harvard, Stanford, UCSF, and Scripps Proteostasis Consortium.

August 25, 2020:

Jim becomes consultant for Dewpoint Therapeutics.

August 20, 2020:

Lin's methods paper published in Bio-Protocol

August 19, 2020:

Eddie defends his Ph.D. thesis!!!!!

August 10, 2020:

April's spotlight published in Trends Neurosci.

August 6, 2020:

Bede presents invited seminar at Telluride Science Research Center Virtual Worshop: Biomolecular Interactions in the Cellular Environments.

July 31, 2020:

Good luck to Jacob as he heads off to UMass to pursue his Ph.D.!

July 24, 2020:

Good luck to Linda as she heads off to Drexel University to pursue her MD/Ph.D.!

July 22, 2020:

Bede presents invited seminar to Dewpoint Therapeutics.

July 14, 2020:

Zach defends his Ph.D. thesis!!!!!

July 13, 2020:

Onsite research of Shorter lab ramps up in Phase 2 reopening (50% occupancy).

July 8, 2020:

Hana's review is published in Emerg. Top. Life Sci.

July 1, 2020:

April wins a post-doctoral fellowship from the American Parkinson Disease Association!

June 30, 2020:

Good luck to Alexis as she heads off to UCSF to pursue her Ph.D.!

June 23, 2020:

Ryan's paper on Skd3 published in eLife.

June 8, 2020:

Onsite research of Shorter lab resumes in Phase 1 reopening (25% occupancy).

May 29, 2020:

Bede presents invited seminar at Alzheimer's Afternoons online seminar series.

May 26, 2020:

Charlotte presents virtual poster at the 25th Annual RNA Society Meeting.

May 24, 2020:

Congratulations to our graduating Swarthmore senior Runa Cheng!

May 19, 2020:

Jim presents invited virtual seminar for the Cell & Molecular Biology Seminar Series at St. Jude Children’s Research Hospital.

May 18, 2020:

Congratulations to our graduating Penn seniors Mustafa Salim and Lauren Drake!

April 23, 2020:

Bede presents invited seminar at IDPSIG and friends virtual symposium.

April 20, 2020:

Collaborative work with Dan Southworth at UCSF and Aaron Lucius at UAB on cryo-EM structures of ClpAP translocating substrate published in Nat. Struct. Mol. Biol.!

April 18, 2020:

Collaborative work with Iris Lindberg on proSAAS phase separation posted on BioRxiv

April 16, 2020:

Korrie's paper on tuning Hsp104 specificity to selectively detoxify alpha-synuclein posted on BioRxiv

April 16, 2020:

Preview with Aaron Gitler, Taekjip Ha, and Sua Myong published in Mol. Cell!

April 10, 2020:

Collaborative work with Walter Englander on HXMS of potentiated Hsp104 variants is published in PNAS!!

April 8, 2020:

Hana's Preview is published in Neuron!

March 31, 2020:

Katie is accorded an Honorable Mention from the National Science Foundation.

March 26, 2020:

Zach's paper on therapeutic genetic variation in Hsp104 homologs posted on BioRxiv

March 17, 2020:

All onsite research activities of Shorter lab are suspended due to COVID-19.

March 11, 2020:

Target ALS fund our Industry-Led Consortium on TDP-43 LLPS with Merck, Vivid, and Chris Donnelly!

March 5, 2020:

Ryan presents seminar at the Gitler-Myong-Shorter-Ha (GMSH) Meeting at Johns Hopkins University!

March 4, 2020:

Zach and JiaBei present seminars at the Gitler-Myong-Shorter-Ha (GMSH) Meeting at Johns Hopkins University!

March 3, 2020:

Chris Donnelly presents on collaborative work with Shorter lab at The 20th Annual Packard Center Symposium.

February 11, 2020:

Bede presents seminar at RNP Discussion Group.

January 29, 2020:

Jim presents invited seminar at Keystone Symposium: AAA+ proteins from atomic structures to organisms.

January 28, 2020:

Review with AstraZeneca on ALS clinical trials accepted at Med. Res. Rev.!

January 27-28, 2020:

Amber, Ryan, Allan, Jacob, Eddie Barbieri, Zach, and JiaBei present posters at Keystone Symposium: AAA+ proteins from atomic structures to organisms.

January 27, 2020:

Ryan presents invited seminar at Keystone Symposium: AAA+ proteins from atomic structures to organisms.

January 22, 2020:

Jim presents invited seminar at the Dementia Discovery Fund.

January 18, 2020:

Ryan's paper on Skd3 posted on BioRxiv

January 13, 2020:

JiaBei wins the 2nd Annual Warren Alpert Foundation Distinguished Scholars Fellowship!

January 10, 2020:

R21 proposal funded by the National Institute of Aging (NIA)!

2019

December 30, 2019:

Review with Dean Brown and Heike Wobst on emerging small-molecule therapeutics for ALS/FTD published in Bioorganic & Medicinal Chemistry Letters!

December 27, 2019:

XF-MS study of Hsp104 published in J. Biol. Chem.!

December 11, 2019:

Collaborative work with Gary Kleiger, Rich Gardner, and colleagues on Ssa1/Ssa2 in nuclear protein-quality control published in Mol. Biol. Cell!

December 9, 2019:

Zach presents poster at the ASCB|EMBO 2019 Meeting in Washington D.C.

December 6, 2019:

Bede presents seminar at the Dr. George W. Raiziss 36th Annual Retreat at Skytop Lodge, Poconos. PA!

December 6, 2019:

Eddie Barbieri wins best postoc poster prize at the Dr. George W. Raiziss 36th Annual Retreat at Skytop Lodge, Poconos. PA!

December 5, 2019:

Jim's Department of Defense Amyotrophic Lateral Sclerosis Research Program (ALSRP) Therapeutic Idea Award recommended for funding!

November 16, 2019:

Alexis presents poster at Annual Biomedical Research Conference for Minority Students (ABRCMS) in Anaheim, CA.

November 13, 2019:

Bede's Spotlight published in Trends. Biochem. Sci.

November 12, 2019:

Eddie Chuang presents seminar at the PGG symposium at the National Constitution Center and wins the John S. O'Brien Award for best oral presentation!

November 8, 2019:

JiaBei and Eddie Chuang present at FRD!

October 28, 2019:

Collaborative work with Dan Southworth at UCSF and Aaron Lucius at UAB on cryo-EM structures of ClpAP translocating substrate posted on BioRxiv

October 17, 2019:

Collaborative work with Sua Myong and colleagues on ALS/FTD-linked FUS mutants published in Molecular Cell!

October 17, 2019:

Jim presents invited seminar to Dewpoint Therapeutics.

October 8, 2019:

Charlotte presents seminar at RNP Discussion Group.

October 3, 2019:

Collaborative work with Shuying Sun and colleagues on DDX3X as a repressor of RAN translation published in Neuron! See also Preview by Adrian Isaacs et al. See Packard Center press release.

September 30, 2019:

Eddie Barbieri is awarded a Ruth L. Kirschstein National Research Service Award (NRSA) from the National Institute of Neurological Disorders and Stroke (NINDS)!

August 20, 2019:

Amber, JiaBei, and Meredith's paper on mining disaggregase sequence space is published in Cell Reports!

August 15, 2019:

ALSA funds our work on TDP-43 and FUS phase separation!

August 1, 2019:

Bede presents seminar at the 38th Summer Symposium in Molecular Biology at Penn State.

August 1, 2019:

Hsp104 on the cover of Cold Spring Harb. Perspect. Biol.

July 31, 2019:

Bede presents poster at the 38th Summer Symposium in Molecular Biology at Penn State.

July 30, 2019:

Ryan wins a Blavatnik Family Fellowship in Biomedical Research!

July 20, 2019:

Jim delivers Keynote at the Amyotrophic Lateral Sclerosis and Related Motor Neuron Diseases Gordon Research Seminar at Mount Snow, VT!

July 11, 2019:

The G. Harold & Leila Y. Mathers Foundation funds our work on disaggregases!

July 1, 2019:

Bede wins Post-Doctoral fellowship from the BrightFocus Foundation!

July 1, 2019:

Jim becomes a member of the Drug Discovery for the Nervous System (DDNS) Study Section.

June 18, 2019:

Korrie defends her Ph.D. thesis!!!!!

June 17, 2019:

Mariana Torrente returns from Brooklyn College for special seminar at Penn!

June 5, 2019:

Collaborative work with Meredith Jackrel at Wash U on Hsp104 variants mitigating toxicity of FUS-CHOP and EWS-FLI published in J.Biol.Chem.

June 3, 2019:

Collaborative work with Dan Southworth at UCSF on cryo-EM structures of ClpB translocating substrate published in Nat. Comm.

May 8, 2019:

Jim, Bede, Eddie Barbieri, Charlotte, Linda, and Hana present seminars at the Gitler-Myong-Shorter-Ha (GMSH) Meeting at Penn!

April 30, 2019:

Jim presents seminar at Target ALS Annual Meeting.

April 22, 2019:

Daniel Rodriguez, Baotram Nguyen, and Gracelynn Soesanto cover work on FUS, ALS, and Kapbeta-2 in video: The Implication of Mutated FUS in ALS.

April 22, 2019:

Addie Shelley, Sean Na, and Joseph Chong cover our work in video: Hsp104 Disaggregation of Amyloid Fibrils

April 22, 2019:

Eddie Barbieri featured by ALSA.

April 17, 2019:

Collaborative work with Sandrine Da Cruz, Don Cleveland, and Chris Donnelly featured on the cover of Neuron!

April 15, 2019:

Charlotte is awarded a Ruth L. Kirschstein National Research Service Award (NRSA) from the National Institute of Neurological Disorders and Stroke (NINDS)!

April 12, 2019:

Amber and Korrie present at FRD!

April 5, 2019:

Collaborative work with Aaron Lucius on Hsp104 translocase activity is published in Biophys. J.!!

April 4, 2019:

Jim's editorial is published in J. Biol. Chem.

March 27, 2019:

Collaborative work with Walter Englander on HXMS of Hsp104 is published in PNAS!!

March 22, 2019:

Zach & Korrie's Biophysical Perspective is published in Biophys. J.!

March 20, 2019:

Jim presents colloquium at the Dept. of Chemistry & Biochemistry, University of Toledo.

March 12, 2019:

Bede presents seminar at RNP Discussion Group.

March 7, 2019:

Collaborative work with Sandrine Da Cruz and Don Cleveland on neurotoxic TDP-43 phase separation is published in Neuron! See also Preview by Ben Wolozin and Alzforum coverage.

March 5, 2019:

Bede presents poster at the 64th Annual Meeting of the Biophysical Society in Baltimore.

March 4, 2019:

JiaBei presents poster at the 64th Annual Meeting of the Biophysical Society in Baltimore.

March 4, 2019:

Jim presents seminar at The 19th Annual Packard Center Symposium

March 2, 2019:

Jim presents invited seminar for the IDP subgroup at the 64th Annual Meeting of the Biophysical Society in Baltimore!

March 1, 2019:

Good luck to Lin as she heads off to establish her own research program as an Assistant Professor in the Department of Biochemistry & Molecular Biology at Jefferson University!

February 27, 2019:

Collaborative work with Chris Donnelly on RNA antagonizing toxic TDP-43 phase separation is published in Neuron! See Preview by Ben Wolozin, Pitt press release, Alzforum, and Nature coverage.

February 27, 2019:

Jim presents invited seminar at the AFTD workshop in Miami.

February 25, 2019:

Jim presents invited seminar at Pathology & Lab Medicine Grand Rounds at Penn.

February 20, 2019:

Bede wins poster prize at the NYAS meeting on phase separation in biology and disease!

February 19, 2019:

Baotram and Ouen featured in Daily Pennsylvanian as leaders of Penn Heroes Club!

February 14, 2019:

Collaborative work with Len Petrucelli on C9orf72 poly(PR) toxicity is published in Science!! See Alzforum coverage.

February 12, 2019:

Review with Dan Southworth published in Cold Spring Harb. Perspect. Biol.!

February 12, 2019:

AstraZeneca visit Penn for Target ALS consortium update.

February 5, 2019:

Target ALS/ALS Finding a cure (ALSFAC) Industry-Led Consortium with AstraZeneca, Aaron Gitler, and Steve Finkbeiner recommended for funding!

February 1, 2019:

Jim presents invited seminar at the Stanford Brain Rejuvenation Project Mini-Symposium at the Wu Tsai Neurosciences Institute at Stanford.

January 31, 2019:

Jim visits the Southworth lab at UCSF.

January 18, 2019:

R21 proposal funded by the National Institute of Aging (NIA)!

January 16, 2019:

Lin and Charlotte's review on nuclear-import receptors published in Trends Cell Biol.!

January 16, 2019:

Disaggregase strategy featured in Science.

2018

December 27, 2018:

Zach's paper in collaboration with Wah Chiu and Andrzej Joachimiak on C. thermophila Hsp104 structure and function published in Structure.

December 21, 2018:

Science features Lin Guo's Cell paper among others as a runner-up for the 2018 Breakthrough of the Year (How cells marshal their contents).

December 19, 2018:

ALS Research Forum features our collaborative work with Nancy Bonini.

December 17, 2018:

Eddie Barbieri's News & Views published in Nat. Neurosci.!

December 12, 2018:

Leeanne, Ed, and Lin's latest paper published in Biochemistry!

December 11, 2018:

Lin and Charlotte present posters at the ASCB|EMBO 2018 Meeting in San Diego.

December 10, 2018:

Zach, Eddie Chuang, and Ryan present posters at the ASCB|EMBO 2018 Meeting in San Diego.

December 7, 2018:

The Role of AAA+ Proteins in Protein Repair and Degradation, ebook published online.

December 3, 2018:

Bede's Preview published in Dev. Cell.

December 1, 2018:

Jim presents invited seminar at Cold Spring Harbor Laboratory Meeting. Neurodegenerative Diseases: Biology & Therapeutics.

November 27, 2018:

Jim presents invited seminar at the Dept. of Anatomy and Neurobiology, University of Maryland School of Medicine in Baltimore, MD.

November 19, 2018:

Hana is awarded an AstraZeneca Post-Doctoral Fellowship!

November 13, 2018:

Lin presents seminar at RNP Discussion Group.

November 9, 2018:

Ryan wins poster prize at the Dr. George W. Raiziss 35th Annual Retreat at Skytop Lodge, Poconos. PA!

November 8, 2018:

Bede is awarded an American Heart Association post-doctoral fellowship!

November 8, 2018:

Jim presents invited seminar at the USF Health Byrd Alzheimer’s Center and Research Institute in Tampa, FL.

November 2, 2018:

Jim presents invited seminar at the 2nd Annual Massachusetts ALS Partnership Symposium in Cambridge, MA.

October 31, 2018:

Collaborative work with Roy Parker on TDP-43 myogranules is published in Nature! See also news story at Medical Xpress and News & Views by Lindsay Becker and Aaron Gitler.

October 25, 2018:

Zach wins poster prize at the CNDR 2018 Marian S. Ware Research Retreat!

October 25, 2018:

Lin presents invited seminar at the CNDR 2018 Marian S. Ware Research Retreat.

October 24, 2018:

Jim presents invited seminar at the 18th Eibsee Meeting on Cellular Mechanisms of Neurodegeneration at Lake Eibsee, Germany.

October 23, 2018:

Ryan presents seminar at the PGG symposium at the National Constitution Center and wins the John S. O'Brien Award for best oral presentation!

October 18, 2018:

Jim presents invited seminar at VIB-KU Leuven Center for Brain & Disease Research.

October 8, 2018:

Lin is selected as a Class of 2018 Stat Wunderkind!

October 4, 2018:

Lab is featured in the official ALSA blog!

September 26, 2018:

Collaborative work with Dan Southworth at UCSF on cryo-EM structures of ClpB translocating substrate posted on BioRxiv

September 13, 2018:

Jim presents invited seminar at Dept. of Pharmacology at UTSW.

September 8, 2018:

Editorial with Walid Houry on the The Role of AAA+ Proteins in Protein Repair and Degradation published in Front. Mol. Biosci.

September 5, 2018:

Emily, Mustafa, Lauren, and Baotram present posters at CURF Research Expo and Open House!

September 5, 2018:

Ryan and Korrie present seminars at the MINS “Year of Neurodegenerative Research” Student Kick-off Event!

August 29, 2018:

Collaborative work with Bonini lab led by Leeanne McGurk on nuclear poly(ADP-ribose) as a therapeutic target in ALS is published in Acta. Neuropathol. Commun.

August 27, 2018:

Jim delivers Keynote Lecture at the LiveLikeLou Symposium at the University of Pittsburgh Brain Institute.

August 9, 2018:

Collaborative work with Bonini lab led by Leeanne McGurk and Ed Gomes on poly(ADP-ribose) preventing pathological TDP-43 phase separation is published in Mol. Cell! See also Penn press release, news stories at Fierce Biotech and Endpoints, and Preview by Stepen Boeynaems and Aaron Gitler

July 25, 2018:

Ed Gomes' review is published in J. Biol. Chem.

July 18, 2018:

Eddie Chuang wins a Blavatnik Family Fellowship in Biomedical Research! Meet Eddie and the other 2018 recipients here.

July 17, 2018:

Collaborative work on FUS with Steven Boeynaems and Ludo Van Den Bosch published in Cell Reports!

July 9, 2018:

Ryan is awarded a Ruth L. Kirschstein National Research Service Award (NRSA) from the National Institute of Aging (NIA)!

July 8, 2018:

Charlotte selected as a 2018 predoctoral trainee for Dr. Josh Wand’s T32 Grant: Structural Biology and Molecular Biophysics Training Program

July 1, 2018:

Jim becomes Professor of Biochemistry and Biophysics.

June 25, 2018:

Collaborative work with Steve Bart and Paul Bates on seminal amyloid enhancement of Ebola virus infection published in PNAS. See also Penn press release.

June 24-29, 2018:

Korrie attends the 68th Lindau Nobel Laureate Meeting in Lindau, Germany.

June 21, 2018:

Jim presents two invited seminars at the Annual ENCALS Meeting in Oxford, U.K.

June 16, 2018:

Good luck to Sanny as she heads off to pursue her M.D./Ph.D. at NYU!

June 14, 2018:

Eddie Barbieri wins a Milton Safenowitz Post-Doctoral Fellowship from the ALS Association!

June 12, 2018:

Good luck to Ed Gomes as he heads off to pursue his M.D. at the Perelman School of Medicine at the University of Pennsylvania!

June 7, 2018:

Jim presents invited seminar at the Lankenau Institute for Medical Research.

May 29, 2018:

Good luck to Elena as she heads off to the University of Chicago to pursue her Ph.D.!

May 15, 2018:

Good luck to Olivia as she heads off to Stanford to pursue her M.D./Ph.D.!

May 15, 2018:

Good luck to Saurabh as he heads off to pursue his M.D. at Columbia University!

May 15, 2018:

Good luck to Jacob as he heads off to pursue his M.Res. in Molecular and Cellular Biosciences at Imperial College London!

May 14, 2018:

Zach presents poster at the EMBO|EMBL Symposium on Cellular Mechanisms Driven by Liquid Phase Separation in Heidelberg, Germany.

May 8, 2018:

Elena presents poster at the 7th Annual PREP Regional Symposium at Albert Einstein College of Medicine.

May 3, 2018:

Lin presents seminar at Target ALS Annual Meeting.

May 1, 2018:

Jim presents seminar at Target ALS Annual Meeting.

April 30, 2018:

Korrie presents seminar at AstraZeneca Neuroscience.

April 23, 2018:

Jim delivers the Cecile M. Pickart Memorial Lecture at the Dept. of Biochemistry and Molecular Biology at Johns Hopkins Bloomberg School of Public Health.

April 20, 2018:

Charlotte passes her candidacy exam!!

April 19, 2018:

Jim presents invited seminar at the Dept. of Biochemistry at Emory University.

April 19, 2018:

Lin, Hong Joo, and Henry's paper on nuclear-import receptors reversing aberrant phase transitions of RNA-binding proteins with prion-like domains is published in Cell! See also Mini-Review by Mikhaleva & Lemke in Cell, Penn press release, ALS Research Forum, and Alzforum.

April 17, 2018:

Alex Zhou covers our work on Hsp104 in video: Utilizing Protein Disaggregase Chaperones to Treat Neurodegenerative Diseases: Hsp104.

April 16, 2018:

Bede is featured in eLife.

April 13, 2018:

Eddie, Acacia, and Christina's review on amyloid assembly and disassembly published in J. Cell Sci.!

April 12, 2018:

Mustafa publishes video: Disaggregation of alpha-synuclein amyloid fibrils by Hsp70.

April 12, 2018:

Amber, JiaBei, and Megan's paper is published in FEMS Yeast Res. for a special issue to commemorate Sue Lindquist.

March 27, 2018:

Phase separation review published in Trends Cell Biol.

March 20, 2018:

Jim promoted to Professor of Biochemistry and Biophysics, effective July 1!

March 15, 2018:

Sanny's Preview published in Mol. Cell.

March 14, 2018:

Nature news feature on phase separation.

March 13, 2018:

Lin presents seminar at RNP Discussion Group.

March 6, 2018:

Jim presents seminar at The 18th Annual Packard Center Symposium

March 1, 2018:

Collaborative work with Jiou Wang's lab is published in Mol. Cell.

February 27, 2018:

Korrie is selected to participate in the 68th Lindau Nobel Laureate Meeting!

February 26, 2018:

Ryan presents SPATT seminar.

February 21, 2018:

Ryan presents poster at the 62nd Annual Biophysical Society Meeting in San Francisco.

February 20, 2018:

Jim presents invited seminar at the Davee Dept. of Neurology, Northwestern University Feinberg School of Medicine.

February 19, 2018:

Sanofi supports our work on disaggregases.

February 12, 2018:

Eddie Chuang presents SPATT seminar.

February 9, 2018:

Jim presents invited seminar at the Dept. of Molecular Biology and Genetics, Cornell University.

February 5, 2018:

JiaBei wins an Alzheimer's Association Research Fellowship!

January 30, 2018:

Jim presents invited seminar at the Dept. of Biochemistry & Molecular Biology, University of Chicago.

January 23, 2018:

Jim presents invited seminar at the Dept. of Neurology, University of Massachusetts Medical School.

January 19, 2018:

Lin wins award for outstanding presentation at the 3rd International Brainstorm Symposium at the Center for NeuroGenetics at the University of Florida.

January 19, 2018:

Jim presents invited seminar at the 3rd International Brainstorm Symposium at the Center for NeuroGenetics at the University of Florida.

January 18, 2018:

Lin presents poster at the 3rd International Brainstorm Symposium at the Center for NeuroGenetics at the University of Florida.

January 17, 2018:

Lin presents seminar at the 3rd International Brainstorm Symposium at the Center for NeuroGenetics at the University of Florida.

January 11, 2018:

Jim presents invited seminar at Penn CNDR.