Anesthesiology and Critical Care NIH T32 Trainers
Current and/or Incoming Trainers (Mentors) for Physician Postdoctoral Research Training in Perioperative Medicine (PPRTPM)
Perioperative Health Services Research
Perioperative Health Services |
Primary Department |
Research Interests |
---|---|---|
Meghan Lane-Fall, MD, MSPH (Director) |
Anesthesiology & Critical Care |
The advancement of patient safety with the use of implementation science to advance health equity, high-quality health care, and population health. |
Medicine |
Translational research studies of the risks, pathogenesis, treatment, and outcomes of acute lung injury in the transplant and non-transplant critically ill populations. |
|
Medicine, Epidemiology, and Medical Ethics and Health Policy |
Combining empirical approaches from the fields of epidemiology, health services research, and the decision-making sciences with conceptual work grounded in moral philosophy. |
|
Anesthesiology & Critical Care
|
Understanding the health-system level determinants of long-term outcomes of surgery and acute care among older adults |
|
CHOP- Anesthesiology & Critical Care
|
All aspects of pediatric critical illness, with a particular emphasis on epidemiology of acute respiratory failure, acute respiratory syndrome (ARDS), and mechanical ventilation. |
Perioperative Neuropharmacology Research
Perioperative Neuropharmacology Faculty |
Primary Department |
Research Interests |
---|---|---|
Alexander Proekt, MD, PhD (Director) |
Anesthesiology & Critical Care |
Neuroscience, Neurophysiology, Computational Neuroscience, Systems Neuroscience |
Seema Bhatnagar, PhD | CHOP-Anesthesiology & Critical Care | Understanding why some individuals are vulnerable or resilient to the potentially adverse effects of chronic stress and how chronic stress contributes to the development of affective and anxiety disorders, including post-traumatic stress disorder. |
Julie Blendy, PhD | Pharmacology | The molecular basis for the biochemical and behavioral changes associated with chronic drug use and addiction. |
Grace Brannigan, PhD | Center for Computational and Integrative Biology, Rutgers University, Camden | The mechanisms underlying general anesthetic actions, employing high performance computing and molecular dynamics simulation to investigate biophysical interactions of proteins, membranes, and small molecules. |
Anesthesiology & Critical Care |
Cellular & Molecular Mechanisms of Anesthetics & Psychedelic Actions in Cerebral Cortices |
|
CHOP-Anesthesiology & Critical Care |
Injury-induced altered brain excitability, circuit rearrangement and synaptic function |
|
Neuroscience |
Representation of information in thalamocortical networks. Intracellular and optical recordings in vivo. |
|
Manuel Covarrubias, PhD | Neuroscience, Thomas Jefferson University |
The molecular mechanisms governing the function and regulation of voltage-gated potassium channels expressed in the nervous system. |
Anesthesiology & Critical Care |
Perioperative neurocognitive disorders in older adults. |
|
Anesthesiology & Critical Care |
Molecular pharmacology of anesthetics and perioperative neurocognitive disorders. |
|
Amelia Eisch, PhD | CHOP-Anesthesiology & Critical Care |
How adult neurogenesis in the hippocampus influences normal behavior and cognitive functioning, as well as abnormal functioning, specifically psychiatric, and neurological disorders. |
Raquel Gur, MD, PhD | Psychiatry |
The study of brain and behavior in psychosis across the lifespan, employing translational research integrating basic and clinical neuroscience. |
Anesthesiology & Critical Care |
How general anesthetic drugs, which vary drastically on a molecular level, all lead to the same endpoint of unconsciousness/hypnosis. |
|
CHOP-Anesthesiology & Critical Care |
Metabolism and mitochondrial bioenergetic dysfunction in in vitro and in vivo models of critical illness alongside exploring therapeutic approaches for organ failure. |
|
Neurology |
Epilepsy, EEG, Clinical Neurophysiology, Brain Stimulation, Implantable devices, network neuroscience, deep brain stimulation, functional imaging, neuroengineering, biomedical engineering, computational neuroscience. |
|
Anesthesiology & Critical Care |
Neural circuits contributing to anesthetic hypnosis and recovery |
|
Vladimir Muzykantov, MD, PhD | Institute for Translational Medicine and Therapeutics | To boost mechanistic and spatiotemporal precision, effectiveness and safety of pharmacotherapy for cardiovascular, pulmonary, oncologic, metabolic, neurologic and other diseases. |
Huafeng Wei, MD, PhD | Anesthesiology & Critical Care | Investigating the role of intracellular calcium dysregulation on neuronal apoptosis, autophagy and neurodegeneration in cellular and animal models featuring various neurodegenerative diseases, especially in Alzheimer’s disease (AD). |
Perioperative Pain Research
Perioperative Pain Medicine Faculty |
Primary Department |
Research Interests |
---|---|---|
Gregory Corder, MD, PhD (Director) |
Psychiatry |
The neural basis of how the brain generates the perception of pain, and how pathological dysfunction within these brain networks promotes the transition to chronic pain and drug abuse. |
Michael Ashburn, MD | Anesthesiology & Critical Care | Large, multi-center clinical trials to evaluate the safety and efficacy of analgesics for the treatment of chronic pain. |
Pharmacology |
Molecular Basis of Addiction and Depression |
|
CHOP- Anesthesiology & Critical Care |
Neural circuitry underlying opioid addiction and neurological disorders. |
|
Biostatistics, Epidemiology, and Informatics |
Efficacy of pain therapeutics, design of pain clinical trails, and functional brain imaging in people with pain. |
|
Renyu Liu, MD, PhD | Anesthesiology & Critical Care |
Opioid and opioid receptor pharmacology, specifically the molecular recognition mechanism of opioids and their receptors using biophysical, biochemical, thermodynamic, protein engineering, and high-resolution structural approaches and the pharmacological effects of opioid receptor agonists. |
Neuroscience |
Molecular, Genetic, and Behavioral Studies of Somatosensation |
|
Anesthesiology & Critical Care |
Understanding the health-system level determinants of long-term outcomes of surgery and acute care among older adults |
|
Rosemary C Polomano, PhD, RN, FAAN | School of Nursing | Instrument development and testing of patient-reported outcome measures, advancing the translation of pain science to practice, and care of patients with cancer-related pain and military service members and Veterans experiencing pain from combat-related injuries. |